DY257714

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: ITCH_MOUSE (E3 ubiquitin-protein ligase Itchy OS=Mus musculus GN=Itch PE=1 SV=2)

HSP 1 Score: 98.5969 bits (244), Expect = 9.050e-20
Identity = 75/238 (31.51%), Postives = 115/238 (48.32%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPG-YPDYILKPGDENVDIN--NLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRREL----WEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLI 886
            ++YFR +GR +A AL  G+ +D  FS  FYK +L   + L D+   D EF   L     I  ++ ++E       E  +++ F         +D  + G    + LKP   N+ +   N EEYI +V +  +  G+  Q +AF  GFN++     LQ F   EL+ LLCG +E+    W+  A+  H      YT  S  I+   + + E   +++    QFVTG  RLP GG A L+
Sbjct:  596 LKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSL-----IWVKENNIE-------ECGLEMYFS--------VDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRH------YTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLM 807          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: ITCH_HUMAN (E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens GN=ITCH PE=1 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 1.182e-19
Identity = 73/237 (30.80%), Postives = 109/237 (45.99%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYPDYILKPGDENVDIN--NLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRREL----WEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLI 886
            ++YFR +GR +A AL  G+ +D  FS  FYK +L   + L D+   D EF   L                  +N  E  DL    +  +++     L     + LKP   N+ +   N EEYI +V +  +  G+  Q +AF  GFN++     LQ F   EL+ LLCG +E+    W+  A+  H      Y   S  I+   + + E   +++    QFVTG  RLP GG A L+
Sbjct:  635 LKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSL--------------IWVKENNIEECDLEMYFSVDKEI-----LGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRH------YARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLM 846          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: HACE1_HUMAN (E3 ubiquitin-protein ligase HACE1 OS=Homo sapiens GN=HACE1 PE=1 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 3.439e-19
Identity = 70/258 (27.13%), Postives = 121/258 (46.90%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYPDYI-------LKPGDENVDI--NNLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRRELWEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLIPKLTIVRKHSSTAPNTPS 940
            + YFR  G+++  AL   +L+++ F+ +FYK +LG  ++  D+   D E+ K LQ +               DN             I DL L+ T     D         LKPG  ++ +  NN  EY+ LV +  +   I  Q+ AF  GF+     + +Q+F  +EL+ LL G  E+ + +   ++ ++  GY  + P I    E++ + T +++    QFVTG+ R+P GG A ++    +     +  P TP+
Sbjct:  638 LNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWI--------------LDN------------DISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEI-DVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPN 868          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: HACE1_MOUSE (E3 ubiquitin-protein ligase HACE1 OS=Mus musculus GN=Hace1 PE=2 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 7.661e-19
Identity = 70/258 (27.13%), Postives = 120/258 (46.51%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYPDYI-------LKPGDENVDI--NNLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRRELWEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLIPKLTIVRKHSSTAPNTPS 940
            + YFR  G+++  AL   +L+++ F+ +FYK +LG  ++  D+   D E+ K LQ +               DN             I DL L+ T     D         LKPG  ++ +  NN  EY+ LV +  +   I  Q+ AF  GF+     + +Q+F  +EL+ LL G  E+ +     ++ ++  GY  + P I    E++ + T +++    QFVTG+ R+P GG A ++    +     +  P TP+
Sbjct:  638 LNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWI--------------LDN------------DISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEI-DVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPN 868          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: WWP1_MOUSE (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Mus musculus GN=Wwp1 PE=1 SV=2)

HSP 1 Score: 92.8189 bits (229), Expect = 4.966e-18
Identity = 72/237 (30.38%), Postives = 108/237 (45.57%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYPDYILKPGDENVDIN--NLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRREL----WEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLI 886
            + YF  +GR +A AL  G+ +D  FS  FYK +L  +L + D+   D EF   L     I  R  ++E    +    +VD+   G                 + LK G  N+ +   N +EYI L+ +     G+  Q +AF  GFN+V  +  LQ F   EL+ +LCG +E+    W+   +  H      YT  S  I+   + + E   + +    QFVTG  RLP GG A L+
Sbjct:  650 LSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSL-----IWIRDNNIEECGLE-MYFSVDMEILGK-------------VTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRH------YTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELM 861          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: WWP1_HUMAN (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Homo sapiens GN=WWP1 PE=1 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 4.966e-18
Identity = 72/237 (30.38%), Postives = 108/237 (45.57%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYPDYILKPGDENVDIN--NLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRREL----WEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLI 886
            + YF  +GR +A AL  G+ +D  FS  FYK +L  +L + D+   D EF   L     I  R  ++E    +    +VD+   G                 + LK G  N+ +   N +EYI L+ +     G+  Q +AF  GFN+V  +  LQ F   EL+ +LCG +E+    W+   +  H      YT  S  I+   + + E   + +    QFVTG  RLP GG A L+
Sbjct:  654 LSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSL-----IWIRDNNIEECGLE-MYFSVDMEILGK-------------VTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRH------YTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELM 865          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: UBE3A_HUMAN (Ubiquitin-protein ligase E3A OS=Homo sapiens GN=UBE3A PE=1 SV=4)

HSP 1 Score: 92.0485 bits (227), Expect = 8.470e-18
Identity = 74/249 (29.72%), Postives = 120/249 (48.19%), Query Frame = 2

Query:  203 FRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLP-----GYPD-YILKPGDENVDINN--LEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQ-IFTPHELDHLLCGRRELWEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLIPKLTIVRKHSST 922
            F L+G V+  A+ +  +LD+ F    Y+ ++G +    D           L + H ++   Q L+ +          L + G   +D+ + F +      G P  Y LK   + + I N   +E+++L  D  +   + +Q +AFR GF+ V + + L+ +F P E++ L+CG R L +  AL E  ++D GYT  S  I    EI+  FT +Q+R F QF TG  R P GGL  L  K+ I +    T
Sbjct:  612 FTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRD-----------LGDSHPVLY--QSLKDL----------LEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNL-DFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKL--KMIIAKNGPDT 834          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: NEDD4_DROME (E3 ubiquitin-protein ligase Nedd-4 OS=Drosophila melanogaster GN=Nedd4 PE=1 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 1.106e-17
Identity = 73/271 (26.94%), Postives = 118/271 (43.54%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYPD-YILKPGDENVDINN--LEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRRELWEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLI----PKLTIVRKHSSTAPNTPSNGNGAFGISGRMTWP 985
            + YF+ +GR+   A+  G+LLD  F   FYK++L   +DL D+   D E+   L  +               +N    ++L F        CLD  + G    + LKPG  N+D+ N   +EYI LV++      +  QM +F  GF  +  +  ++IF  HEL+ L+CG + + +     E+  +   Y      I      +  F+ + +    QFVTG  R+P  G   L     P++  + K       TP+N   A     R+  P
Sbjct:  739 LSYFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQKPIDLKDMESVDTEYYNSLMWI--------------KENDPRILELTF--------CLDEDVFGQKSQHELKPGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELLMCGIQNI-DVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQMFTIEKW-----GTPNNFPRAHTCFNRLDLP 981          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: NEDD4_HUMAN (E3 ubiquitin-protein ligase NEDD4 OS=Homo sapiens GN=NEDD4 PE=1 SV=3)

HSP 1 Score: 89.3521 bits (220), Expect = 5.490e-17
Identity = 69/233 (29.61%), Postives = 111/233 (47.64%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYP-DYILKPGDENVDI--NNLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRRELWEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVL 883
            + YF+ +GRV   A+  G+LLD  F   FYK++L   + LHD+   D+E+   L+ +               +N    +DLRF         +D  L G    + LK G   + +   N +EYI LV+       I +QM AF+ GF ++     ++IF  +EL+ L+CG  ++ +     EH K+ +GY+A    I    + +     +++    QFVTG  R+P  G A L
Sbjct: 1051 LSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWI--------------LENDPTELDLRF--------IIDEELFGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDV-DVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAEL 1260          

BLAST of DY257714 vs. ExPASy Swiss-Prot
Match: HACE1_XENTR (E3 ubiquitin-protein ligase HACE1 OS=Xenopus tropicalis GN=hace1 PE=2 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.597e-16
Identity = 65/240 (27.08%), Postives = 109/240 (45.42%), Query Frame = 2

Query:  194 IEYFRLLGRVMAKALQDGRLLDLPFSTAFYKLVLGHELDLHDIIPFDAEFGKILQELHVIICRKQHLESMTSDNCEEAVDLRFRGAPIEDLCLDFTLPGYPDYI-------LKPGDENVDIN--NLEEYISLVVDATVKTGIMRQMEAFRAGFNQVFDITSLQIFTPHELDHLLCGRRELWEPAALAEHIKFDHGYTAKSPAIVNLLEIMGEFTPDQQRAFCQFVTGAPRLPPGGLAVLI 886
            + YFR  G ++  AL   +L+++ F+ +FYK +LG  ++  D+   D E+ K LQ +               DN             I DL L+ T     D         LKPG  ++ +   N  EY+ LV +  +   I  Q+  F  GF+     + +Q+F  +EL+ LL G  E+ +     ++ ++  GY      I    E++ E T +++    QFVTG+ R+P GG A ++
Sbjct:  641 LNYFRFAGEILGLALYHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWI--------------LDN------------DISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINGFLQGFHMFIPPSLIQLFDEYELELLLSGMPEI-DVNDWMKNTEYTSGYERDDQVIQWFWEVVQELTQEERVLLLQFVTGSSRVPHGGFAYIM 853