EY659537

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2_DICDI (SUMO-activating enzyme subunit 2 OS=Dictyostelium discoideum GN=uba2 PE=3 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 2.417e-36
Identity = 79/205 (38.54%), Postives = 131/205 (63.90%), Query Frame = 3

Query:   57 LSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHITKKMLLMPVEPYEPNKSCYVCSETPLSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGD-DLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEFDDE 668
            +++DKDD+LA+ FV +A+NIR+  FGI + S F+ K +AGNI+ A+ATTNA+I GLIV+EAIKV+    D+   TY  +  + K LLMP +    N  C+VC+ + +   +NT ++ +  F++ ++K  L +N P++  G++++Y+ GD DL + E+   +   +K L+     +TN T L VED  Q+  + I I+H  +FD++
Sbjct:  338 MTWDKDDELALSFVCSASNIRSKIFGIPMKSRFDVKSMAGNIIPAIATTNAVIGGLIVMEAIKVVDGRFDQCLSTYLYQLPSGKRLLMPTQLEPQNPKCFVCNRSFIICRLNTEKTTISQFIDHVLKKSLAVNEPILTVGNDIIYEGGDQDLSKEEIEQRSKIEKKTLA--THRLTNDTSLVVEDYNQDFQITITIQHTTDFDED 540          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2_DANRE (SUMO-activating enzyme subunit 2 OS=Danio rerio GN=uba2 PE=1 SV=2)

HSP 1 Score: 131.339 bits (329), Expect = 7.532e-30
Identity = 91/264 (34.47%), Postives = 143/264 (54.17%), Query Frame = 3

Query:   36 REKEIG-NLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHIT-KKMLLMPVEPYEPNKSCYVCSETP-LSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEFDDEKEPDGNALSGWTXAXXSKDDKQSMNDKQSIGNGGDSSNALQTEPADAVKD 818
            +EK  G  L +DKDD  A++FVTAA+N+R   F +++ S F+ K +AGNI+ A+ATTNA+IAGLIV+EA+K+L  D ++ R  +  +    +K LL+P     PN SCYVC+  P +++++N  ++ ++   +KI+K K G+  P +     +    G  L   E     AN  K LS     + NG+ L  +D  Q+ TL +N+ H EE   EK+ +   +     A        +  + ++I NG   S    T    AV+D
Sbjct:  339 KEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFSMNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKILNSDFEQCRTIFLNKQPNPRKKLLVPCALDPPNASCYVCASKPEVTVKLNVHKTMVQALQDKILKEKFGMVAPDV----QIEDGKGTILISSEEGETEANNNKFLSDF--GIRNGSRLQADDFLQDYTLLVNVIHSEEL--EKDVEFEVVG---DAPDKAPAPSAPEEGKNIANGNKDSAQPSTSSKAAVED 591          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2_XENTR (SUMO-activating enzyme subunit 2 OS=Xenopus tropicalis GN=uba2 PE=2 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.678e-29
Identity = 91/265 (34.34%), Postives = 142/265 (53.58%), Query Frame = 3

Query:   36 REKEIG-NLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHIT-KKMLLMPVEPYEPNKSCYVCSETP-LSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEFDDEKEPDGNALSGWTXAXXSKDDKQSMNDKQSIGNGGDSSNALQTEPADAVKDV 821
            REK  G  L +DKDD  A++FVTAAAN+R   F +++ S F+ K +AGNI+ A+ATTNA+I+GLIV+E +K+L  +T++ R  +  +    +K LL+P     PN SCYVC+  P +++++N  +  ++   +KI+K K    F ++     +    G  L   E     AN  + +S+    + N + L  +D  Q+ TL INI H +E   EK+ D   +         K  +QS+   ++I NG D      T  A    DV
Sbjct:  332 REKGNGAELVWDKDDPPAMDFVTAAANLRMHIFSMNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKLNVHKVTVQMLQDKILKEK----FAMVAPDVQIEDGKGTILISSEAGETDANNNRKISEF--GIRNSSQLQADDFLQDYTLMINILHSDEM--EKDVDFEVVGDVPEKGPQKPSEQSV---KNITNGSDDGAQPSTSKAQDQDDV 585          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2_HUMAN (SUMO-activating enzyme subunit 2 OS=Homo sapiens GN=UBA2 PE=1 SV=2)

HSP 1 Score: 129.798 bits (325), Expect = 2.192e-29
Identity = 98/277 (35.38%), Postives = 144/277 (51.99%), Query Frame = 3

Query:    6 LEALKLFFATREKEIG-NLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHIT-KKMLLMPVEPYEPNKSCYVCSETP-LSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEF--DDEKEPDGNALSGWTXAXXSKDDKQSMNDKQSIGNGGDSSNALQTEPADAVKDV 821
            +E L++  A  EK  G  L +DKDD  A++FVT+AAN+R   F +++ S F+ K +AGNI+ A+ATTNA+IAGLIV+E +K+L    D+ R  +  +    +K LL+P     PN +CYVC+  P +++ +N  +  +    +KIVK K    F ++     +    G  L   E     AN  K LS+    + NG+ L  +D  Q+ TL INI H E+   D E E  G+       A      KQ+ +  +SI NG D      T  A    DV
Sbjct:  326 IETLRVHLA--EKGDGAELIWDKDDPSAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEK----FAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEF--GIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGD-------APEKVGPKQAEDAAKSITNGSDDGAQPSTSTAQEQDDV 587          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2_MOUSE (SUMO-activating enzyme subunit 2 OS=Mus musculus GN=Uba2 PE=2 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 8.328e-29
Identity = 97/277 (35.02%), Postives = 143/277 (51.62%), Query Frame = 3

Query:    6 LEALKLFFATREKEIG-NLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHIT-KKMLLMPVEPYEPNKSCYVCSETP-LSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEF--DDEKEPDGNALSGWTXAXXSKDDKQSMNDKQSIGNGGDSSNALQTEPADAVKDV 821
            +E L++  A  EK  G  L +DKDD  A++FVT+AAN+R   F +++ S F+ K +AGNI+ A+ATTNA+IAGLIV+E +K+L    D+ R  +  +    +K LL+P     PN +CYVC+  P +++ +N  +  +    +KIVK K    F ++     +    G  L   E     AN  K LS     + NG+ L  +D  Q+ TL INI H E+   D E E  G+       +      KQ+ +  +SI NG D      T  A    DV
Sbjct:  324 IETLRVHLA--EKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEK----FAMVAPDVQIEDGKGTILISSEEGETEANNPKKLSDF--GIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGD-------SPEKVGPKQAEDAAKSIANGSDDGAQPSTSTAQEQDDV 585          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2B_XENLA (SUMO-activating enzyme subunit 2-B OS=Xenopus laevis GN=uba2-B PE=2 SV=2)

HSP 1 Score: 127.102 bits (318), Expect = 1.420e-28
Identity = 89/265 (33.58%), Postives = 142/265 (53.58%), Query Frame = 3

Query:   36 REKEIG-NLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHIT-KKMLLMPVEPYEPNKSCYVCSETP-LSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEFDDEKEPDGNALSGWTXAXXSKDDKQSMNDKQSIGNGGDSSNALQTEPADAVKDV 821
            REK  G  L +DKDD  A++FVTAAAN+R   F +++ S F+ K +AGNI+ A+ATTNA+I+GLIV+E +K+L  +T++ R  +  +    +K LL+P     PN SCYVC+  P +++++N  +  ++   +KI+K K    F ++     +    G  L   E     AN  + +S+    + N + L  +D  Q+ TL +NI H +E   EK+ D   +         K  ++S+   ++I NG D      T  A    DV
Sbjct:  332 REKGDGAELVWDKDDVPAMDFVTAAANLRMHIFSMNMKSKFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKLNVHKVTVQMLQDKILKEK----FAMVAPDVQIEDGKGTILISSEAGETDANNHRKISEF--GIRNSSQLQADDFLQDYTLMMNILHSDEM--EKDVDFEVVGDVPEKGPQKPPEESV---KNITNGSDDGAQPSTSKAQDQDDV 585          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2A_XENLA (SUMO-activating enzyme subunit 2-A OS=Xenopus laevis GN=uba2-A PE=2 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 1.420e-28
Identity = 89/265 (33.58%), Postives = 142/265 (53.58%), Query Frame = 3

Query:   36 REKEIG-NLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHIT-KKMLLMPVEPYEPNKSCYVCSETP-LSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEFDDEKEPDGNALSGWTXAXXSKDDKQSMNDKQSIGNGGDSSNALQTEPADAVKDV 821
            REK  G  L +DKDD  A++FVTAAAN+R   F +++ S F+ K +AGNI+ A+ATTNA+I+GLIV+E +K+L  +T++ R  +  +    +K LL+P     PN SCYVC+  P +++++N  +  ++   +KI+K K    F ++     +    G  L   E     AN  + +S+    + N + L  +D  Q+ TL +NI H +E   EK+ D   +         K  ++S+   ++I NG D      T  A    DV
Sbjct:  332 REKGDGAELVWDKDDVPAMDFVTAAANLRMHIFSMNMKSKFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKLNVHKVTVQMLQDKILKEK----FAMVAPDVQIEDGKGTILISSEAGETDANNHRKISEF--GIRNSSQLQADDFLQDYTLMMNILHSDEM--EKDVDFEVVGDVPEKGPQKPPEESV---KNITNGSDDGAQPSTSKAQDQDDV 585          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: UBA2_SCHPO (Ubiquitin-activating enzyme E1-like OS=Schizosaccharomyces pombe GN=uba2 PE=1 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 3.065e-23
Identity = 71/183 (38.80%), Postives = 102/183 (55.74%), Query Frame = 3

Query:   54 NLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHITKKMLLMPVEPYEPNKSCYVCSETPLSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTV 602
            +LSFDKDD+  ++FV AAAN+RA  FGI   S F+ K +AGNI+ A+ATTNA+IAGL + +AIKVL  D +  +  Y  +  T+  +L   +  +PN  C  CS   L L +N     LR  V+ I+K++L  +  + +    L+YD   D D+        NL+K    L       T+LTV
Sbjct:  333 DLSFDKDDKDTLDFVAAAANLRAHVFGIQQLSEFDIKQMAGNIIPAIATTNAVIAGLCITQAIKVLQGDLNDLKNIYLAKRPTR--VLHCEKTCKPNPYCPTCSFVLLQLGVNDKNMTLRVLVDDILKSRLHYSEEVSVLNDKLIYD--PDFDD--------NLDKTFDDLGINPAKNTILTV 503          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: SAE2_CAEEL (SUMO-activating enzyme subunit uba-2 OS=Caenorhabditis elegans GN=uba-2 PE=2 SV=3)

HSP 1 Score: 104.76 bits (260), Expect = 7.550e-22
Identity = 75/250 (30.00%), Postives = 126/250 (50.40%), Query Frame = 3

Query:   57 LSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVLLKDTDKYRMTYCLEHITKKMLLMPVEPYE-PNKSCYVCSE-TPLSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSNLLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEF--DD------EKEPDGNALSGWTXAXXSKDDKQSMNDKQSIGNGGDS 776
            L+FDKD  + + FV A ANIRA  FGI + S F+ K +AGNI+ A+A+TNAI+AG+IV EA++V+   T     +        +  +   +    PN  C+VCSE   + + +N     +    EK++K KL +  P +M  +     V  D D  ++      L K L+++   + +G +L+ +D QQE+ + + IK  +    DD      EKEP+ +            + K+   +++   NG ++
Sbjct:  332 LAFDKDHAIIMSFVAACANIRAKIFGIPMKSQFDIKAMAGNIIPAIASTNAIVAGIIVTEAVRVIEGSTVICNSSIATTQSNPRGRIFGGDATNPPNPRCFVCSEKREVFIYVNPDTMTVGGLCEKVLKQKLNMLAPDVMDSATSRIIVSSDGDTDDL------LPKKLAEV--SIEDGAILSCDDFQQEMEIKLFIKKGDRLAGDDFEVARSEKEPEPDDRKRKADGSEEPEAKRQKVEEKDDKNGNEA 573          

BLAST of EY659537 vs. ExPASy Swiss-Prot
Match: UBA2_YEAST (Ubiquitin-activating enzyme E1-like OS=Saccharomyces cerevisiae GN=UBA2 PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 6.844e-15
Identity = 71/225 (31.56%), Postives = 115/225 (51.11%), Query Frame = 3

Query:   42 KEIGNLSFDKDDQLAVEFVTAAANIRAASFGISLHSLFEAKGIAGNIVHAVATTNAIIAGLIVIEAIKVL----LKDTDKY-----RMTYCLEHITKKMLLMPVEPYEPNKSCYVCSET-----PLSLEINTSRSKLRDFVEKIVKAKLGINFPLIMHGSN--LLYDVGDDLDEVEVANYAANLEKVLSQLPSPVTNGTMLTVEDLQQELTLHINIKHREEFDDE 668
            KE  ++ FDKDD   +EFV  AANIR+  F I + S+F+ K IAGNI+ A+ATTNAI+AG   + +++VL       T KY       T    ++++   L   +   PNK+C VCS+       LS +   ++ KL DFV  I +         ++  SN  LL+D   D +++         ++ LS++   + NG+++   D + +  +   I+   + DDE
Sbjct:  323 KEQNHIEFDKDDADTLEFVATAANIRSHIFNIPMKSVFDIKQIAGNIIPAIATTNAIVAGASSLISLRVLNLLKYAPTTKYTDLNMAFTAKASNLSQNRYLSNPKLAPPNKNCPVCSKVCRGVIKLSSDC-LNKMKLSDFVVLIREKYSYPQDISLLDASNQRLLFDY--DFEDLN--------DRTLSEI--NLGNGSIILFSDEEGDTMIRKAIELFLDVDDE 534