DR406174

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: BCKD_RAT ([3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Rattus norvegicus GN=Bckdk PE=1 SV=2)

HSP 1 Score: 121.709 bits (304), Expect = 4.165e-27
Identity = 70/229 (30.57%), Postives = 123/229 (53.71%), Query Frame = 1

Query:   55 AKKLSETFSKTLIEEVGRWGCMKQTGVSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDERDFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELHNPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNIYGDPSFTFPY 741
            +K ++  ++++ I+ V     ++ T   + Y    G      +LL S ++L +ELP+RIA R     +LP+ +   P +L V + Y+ +F+ L  FP I+  +DE  + Q+++ +   H +VV ++A GL++ +K +      ED   +  FLD+   SR+GIRML   H+ LH     P  +G I T++SP ++     + AR +C  +YG+AP   I G  +  FP+
Sbjct:   47 SKTVTSFYNQSAIDVVAEKPSVRLTPTMMLYS---GRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI------EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDK--PDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPF 264          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: BCKD_HUMAN ([3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Homo sapiens GN=BCKDK PE=1 SV=2)

HSP 1 Score: 121.324 bits (303), Expect = 5.440e-27
Identity = 70/229 (30.57%), Postives = 122/229 (53.28%), Query Frame = 1

Query:   55 AKKLSETFSKTLIEEVGRWGCMKQTGVSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDERDFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELHNPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNIYGDPSFTFPY 741
            +K ++  ++++ I+       ++ T   + Y    G      +LL SA++L +ELP+RIA R      LP+ +   P +L V + Y+ +F+ L  FP I+  +DE  + Q+++ +   H +VV ++A GL++ +K +      ED   +  FLD+   SR+GIRML   H+ LH     P  +G I T++SP ++     + AR +C  +YG+AP   I G  +  FP+
Sbjct:   47 SKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYA---GRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI------EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDK--PDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPF 264          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: BCKD_BOVIN ([3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Bos taurus GN=BCKDK PE=2 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 1.212e-26
Identity = 67/198 (33.84%), Postives = 110/198 (55.56%), Query Frame = 1

Query:  148 MMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDERDFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELHNPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNIYGDPSFTFPY 741
            M+  G      +LL SA++L +ELP+RIA R     +LP+ +   P +L V + Y+ +F+ L  FP I+  +DE  + Q+++ +   H +VV ++A GL++ +K +      ED   +  FLD+   SR+GIRML   H+ LH     P  +G I T++SP ++     + AR +C  +YG+AP   I G  +  FP+
Sbjct:   75 MLYSGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEARYCQLVRQLLDDHKDVVTLLAEGLRESRKYI------EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDK--PDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPF 264          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: BCKD_MOUSE ([3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Mus musculus GN=Bckdk PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 2.700e-26
Identity = 65/198 (32.83%), Postives = 109/198 (55.05%), Query Frame = 1

Query:  148 MMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDERDFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELHNPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNIYGDPSFTFPY 741
            M+  G      +LL S ++L +ELP+RIA R     +LP+ +   P +L V + Y+ +F+ L  FP I+  +DE  + Q+++ +   H +VV ++A GL++ +K +      +D   +  FLD+   SR+GIRML   H+ LH     P  +G I T++SP ++     + AR +C  +YG+AP   I G  +  FP+
Sbjct:   75 MLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI------QDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDK--PDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPF 264          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: PDK2_RAT ([Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial OS=Rattus norvegicus GN=Pdk2 PE=1 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 7.352e-24
Identity = 74/200 (37.00%), Postives = 105/200 (52.50%), Query Frame = 1

Query:  133 VSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDER---DFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELH----NPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNI 711
            +S++  ++FGS    +    S  FL +ELP+R+A    E+  LP  +   P+V  V+ WY+ S  D+  F D +   D R    FT  +  I+ RHN+VVP MA G+ + K       V      I  FLDRFY+SRI IRMLI QH  +     NP  P H IG ID   S   V ++A + A+ +C + Y ++PD  I
Sbjct:   31 LSMKQFLDFGSSNACEKT--SFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSN--QNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKH-IGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEI 224          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: PDK2_MOUSE ([Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial OS=Mus musculus GN=Pdk2 PE=1 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 7.352e-24
Identity = 84/239 (35.15%), Postives = 119/239 (49.79%), Query Frame = 1

Query:   19 FVRKQKPEAAMA-AKKLSETFSKTLIEEVGRWGCMKQTGVSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDER---DFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELH----NPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNI 711
            +VR     A++A A K  E FSK              + +S++  ++FGS    +    S  FL +ELP+R+A    E+  LP  +   P+V  V+ WY+ S  D+  F D +   D R    FT  +  I+ RHN+VVP MA G+ + K       V      I  FLDRFY+SRI IRMLI QH  +     NP  P H IG ID   S   V ++A + A+ +C + Y ++PD  I
Sbjct:    3 WVRALLKNASLAGAPKYIEHFSK-----------FSPSPLSMKQFLDFGSSNACEKT--SFTFLRQELPVRLANIMKEINLLPDRVLGTPSVQLVQSWYVQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSN--QNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKH-IGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEI 224          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: PDK3_MOUSE ([Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial OS=Mus musculus GN=Pdk3 PE=2 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 9.602e-24
Identity = 75/215 (34.88%), Postives = 115/215 (53.49%), Query Frame = 1

Query:   94 EEVGRWGCMKQTGVSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDER---DFTQMIKAIKVRHNNVVPMMALGLQQLKKE--MDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELH----NPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNI 711
            +++ R+     + +S++  ++FG     +    S  FL KELP+R+A    E+  LP  L  +P+V  V+ WY+ SF +L  + + +S  D R   +F  ++  I+ RHN+VVP MA G+ + K++   DP I       I  FLDRFY +RI  RMLI QH  L     NP  P H IG ID   +   V ++A E A+ +C + Y  AP+  +
Sbjct:   14 KQIERYSRFSPSPLSIKQFLDFGRDNACEKT--SYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYEN-KSPEDPRVLDNFLNVLINIRNRHNDVVPTMAQGVIEYKEKFGFDPFI----SSNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPAHPKH-IGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEV 220          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: PDK2_HUMAN ([Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial OS=Homo sapiens GN=PDK2 PE=1 SV=2)

HSP 1 Score: 110.538 bits (275), Expect = 9.602e-24
Identity = 73/200 (36.50%), Postives = 106/200 (53.00%), Query Frame = 1

Query:  133 VSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDER---DFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELH----NPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNI 711
            +S++  ++FGS    +    S  FL +ELP+R+A    E+  LP  +   P+V  V+ WY+ S  D+  F D +   D R    FT  +  I+ RHN+VVP MA G+ + K       V      I  FLDRFY+SRI IRMLI QH  +     NP  P H IG ID   +  +V ++A + A+ +C + Y ++PD  I
Sbjct:   31 LSMKQFLDFGSSNACEKT--SFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSN--QNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKH-IGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEI 224          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: PDK_DROME ([Pyruvate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Drosophila melanogaster GN=Pdk PE=2 SV=2)

HSP 1 Score: 110.153 bits (274), Expect = 1.254e-23
Identity = 71/196 (36.22%), Postives = 102/196 (52.04%), Query Frame = 1

Query:  133 VSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDE-RDFTQMIKAIKVRHNNVVPMMALGLQQLKKEMDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELH--NPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNI 711
            +S++  M+FG    +K   I   FL KELP+R+A    E+  LP  L    +V +V  WY+ SF D+  +     T D  + F   +  I+ RHN+VV  MA G+ ++K+    ++       I  FLDR YMSRI IRMLI QH  L   NP+     IG +D       V R+A E+AR +C + Y ++P   I
Sbjct:   33 LSIKQFMDFGQNACEKKSYI---FLRKELPVRLANIMKEIALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEPTHDNLQKFVADLDLIRNRHNDVVQTMAQGVIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGGNPHAGGRHIGCLDPACDLSDVVRDAYENARFLCDQYYLTSPALEI 225          

BLAST of DR406174 vs. ExPASy Swiss-Prot
Match: PDK3_HUMAN ([Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial OS=Homo sapiens GN=PDK3 PE=1 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.254e-23
Identity = 74/215 (34.42%), Postives = 116/215 (53.95%), Query Frame = 1

Query:   94 EEVGRWGCMKQTGVSLRYMMEFGSKPTDKNLLISAQFLHKELPIRIARRAIELETLPYGLSEKPAVLKVRDWYLDSFRDLRSFPDIRSTSDER---DFTQMIKAIKVRHNNVVPMMALGLQQLKKE--MDPKIVYEDLDEIHQFLDRFYMSRIGIRMLIGQHVELH----NPNPPPHCIGYIDTKMSPVQVARNASEHARCVCLREYGSAPDFNI 711
            +++ R+     + +S++  ++FG     +    S  FL KELP+R+A    E+  LP  L  +P+V  V+ WY+ SF +L  + + +S  D +   +F Q++  ++ RHN+VVP MA G+ + K++   DP I       I  FLDRFY +RI  RMLI QH  L     NP  P H IG ID   +   V ++A E A+ +C + Y  AP+  +
Sbjct:   14 KQIERYSRFSPSPLSIKQFLDFGRDNACEKT--SYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYEN-KSPEDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFI----STNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPVHPKH-IGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEV 220