DY304645

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: GSK3A_HUMAN (Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2)

HSP 1 Score: 283.878 bits (725), Expect = 9.692e-76
Identity = 147/258 (56.98%), Postives = 194/258 (75.19%), Query Frame = 2

Query:  143 GKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            G+  E  Q ++Y   +V+G GSFG+V+QA+  ET E VAIKKVLQD+R+KNRELQ+MR +DH N++ L++ F+S+   K+EL+LNLV+EYVPE++YRV +H++ A   +P++YVK+Y YQ+FR LAYIH+   VCHRD+KPQNLLVDP T  +K+CDFGSAKQL+ GE N+SYICSR+YRAPELIFGAT+ T+SI++WS GCVLAE      P FPG  S    L +IIKV   P  E +I  +  NYT+ F FP+ K
Sbjct:  108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHS-QGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAE-LLLGQPIFPG-DSGVDQLVEIIKVLGTPTRE-QIREMNPNYTE-FKFPQIK 360          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: GSK3A_MOUSE (Glycogen synthase kinase-3 alpha OS=Mus musculus GN=Gsk3a PE=1 SV=2)

HSP 1 Score: 282.722 bits (722), Expect = 2.159e-75
Identity = 147/258 (56.98%), Postives = 193/258 (74.81%), Query Frame = 2

Query:  143 GKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            G+  E  Q ++Y   +V+G GSFG+V+QA+  ET E VAIKKVLQD+R+KNRELQ+MR +DH N++ L++ F+S+   K+EL+LNLV+EYVPE++YRV +H++ A    P+IY+K+Y YQ+FR LAYIH+   VCHRD+KPQNLLVDP T  +K+CDFGSAKQL+ GE N+SYICSR+YRAPELIFGAT+ T+SI++WS GCVLAE      P FPG  S    L +IIKV   P  E +I  +  NYT+ F FP+ K
Sbjct:  108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHS-QGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAE-LLLGQPIFPG-DSGVDQLVEIIKVLGTPTRE-QIREMNPNYTE-FKFPQIK 360          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: GSK3_CAEBR (Glycogen synthase kinase-3 OS=Caenorhabditis briggsae GN=gsk-3 PE=3 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 1.185e-73
Identity = 147/283 (51.94%), Postives = 198/283 (69.96%), Query Frame = 2

Query:   68 DKEMSAAVVDGSDHVTGHIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            +K++ +  +     VT  + S    G + + +  ISY  ++V+G GSFG+VF AK   T E VAIKKVLQD+R+KNRELQ+MR ++HPN++ LK+ F+S+   K+EL+LNL++EYVPE++YRV +HYS   Q +P+IYVKLY YQ+ R LAYIH++  +CHRD+KPQNLL+DP T  +K+CDFGSAK L+  E N+SYICSR+YRAPELIFGAT  T SI++WS G V+AE      P FPG  S    L +IIKV   P  E +I  +  NY + F FP+ K
Sbjct:    2 NKQLLSCSLKSGKQVTMVVASVATDGVDQQVE--ISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNRELQIMRKLNHPNIVKLKYFFYSSGDKKDELYLNLILEYVPETVYRVARHYSKQRQSIPMIYVKLYMYQLLRSLAYIHSIG-ICHRDIKPQNLLIDPETGILKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATNYTNSIDVWSAGTVIAE-LLLGQPIFPG-DSGVDQLVEIIKVLGTPTRE-QIQSMNPNYKE-FKFPQIK 277          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: SGG_DROME (Protein kinase shaggy OS=Drosophila melanogaster GN=sgg PE=1 SV=2)

HSP 1 Score: 276.559 bits (706), Expect = 1.547e-73
Identity = 144/269 (53.53%), Postives = 195/269 (72.49%), Query Frame = 2

Query:  116 GHIISTTIG--GKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFSTTSK-NELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            G  I+T +   G+  +  Q +SY   +V+G GSFG+VFQAK  +TGE VAIKKVLQDRR+KNRELQ+MR ++H N++ L + F+S+  K +E+FLNLV+EY+PE++Y+V + Y+   Q +P+ +++LY YQ+FR LAYIH++  +CHRD+KPQNLL+DP T  +K+CDFGSAKQL+ GE N+SYICSR+YRAPELIFGA   TT I++WS GCVLAE      P FPG  S    L ++IKV   P  E +I  +  NYT+ F FP+ K
Sbjct:  585 GSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHSLG-ICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAE-LLLGQPIFPG-DSGVDQLVEVIKVLGTPTRE-QIREMNPNYTE-FKFPQIK 848          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: GSK3_CAEEL (Glycogen synthase kinase-3 OS=Caenorhabditis elegans GN=gsk-3 PE=1 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 1.547e-73
Identity = 146/283 (51.59%), Postives = 199/283 (70.32%), Query Frame = 2

Query:   68 DKEMSAAVVDGSDHVTGHIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            +K++ +  +     VT  + S    G + + +  ISY  ++V+G GSFG+VF AK   T E VAIKKVLQD+R+KNRELQ+MR ++HPN++ LK+ F+S+   K+EL+LNL++EYVPE++YRV +HYS   Q++P+IYVKLY YQ+ R LAYIH++  +CHRD+KPQNLL+DP +  +K+CDFGSAK L+  E N+SYICSR+YRAPELIFGAT  T SI++WS G V+AE      P FPG  S    L +IIKV   P  E +I  +  NY + F FP+ K
Sbjct:    2 NKQLLSCSLKSGKQVTMVVASVATDGVDQQVE--ISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNRELQIMRKLNHPNIVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYIHSIG-ICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATNYTNSIDVWSAGTVMAE-LLLGQPIFPG-DSGVDQLVEIIKVLGTPTRE-QIQSMNPNYKE-FKFPQIK 277          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: GSK3_DICDI (Glycogen synthase kinase-3 OS=Dictyostelium discoideum GN=gskA PE=1 SV=2)

HSP 1 Score: 258.84 bits (660), Expect = 3.339e-68
Identity = 136/248 (54.84%), Postives = 182/248 (73.39%), Query Frame = 2

Query:  170 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFSTTSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            + Y+ E V+G GSFG+V QA   +T E VAIKKVLQD+RYKNRELQ+M++++H N++SLK+ F+ T+  +E++LNLV+EYVP+++YRV +HYS + Q +P I+VKLY YQ+ R + YIH++  +CHRD+KPQNLL+D  T  +K+CDFGSAK LI GE N+SYICSR YRAPELIFG+T  TT+I++WS GCVLAE      P FPG ++    L +IIKV   P  E +I  +   YT  F FP  K
Sbjct:   54 VCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFY-TSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLG-ICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAE-LLLGQPLFPG-ENGIDQLVEIIKVLGTPTKE-QIHAMNPYYTS-FKFPEIK 295          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: GSK3_SCHPO (Protein kinase gsk3 OS=Schizosaccharomyces pombe GN=gsk3 PE=1 SV=3)

HSP 1 Score: 252.677 bits (644), Expect = 2.393e-66
Identity = 134/265 (50.57%), Postives = 185/265 (69.81%), Query Frame = 2

Query:  122 IISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            I  T   G  GE KQ +SY + +VVG+GSFG+V Q   +E+    AIK+VLQD+R+KNRELQ+MR+M HPN++ L   +++T  + +E++LNLV+E++PE++YR  + Y+     MP++ VKLY YQ+ R LAYIH    +CHRD+KPQNLL+DP    +K+CDFGSAK L+AGE N+SYICSR+YRAPELIFGAT+ T +I+IWS GCV+AE      P FPG +S    L +IIK+   P  E +I  +  NY +   FP+ +
Sbjct:   15 IKETARDGSTGEVKQ-LSYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHA-SGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAE-LMLGHPLFPG-ESGIDQLVEIIKILGTPSRE-QIKTMNPNYME-HRFPQIR 273          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: GSK3H_DROME (Putative glycogen synthase kinase-3 homolog OS=Drosophila melanogaster GN=gskt PE=2 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 5.330e-66
Identity = 130/244 (53.28%), Postives = 180/244 (73.77%), Query Frame = 2

Query:  170 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFSTTSK-NELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFL 898
            ISY   +VVG GSFG+VFQAK + + E VAIKKVLQDRR+KNRELQ+MR + H N+I+LK  FFS+  K +E++LNLVME++PE++Y+V + Y+ A Q +P+ +V+LY YQ+ R + Y+H++   CHRD+KPQN+L+D  T  +K+CDFGSAKQLI+GE N+SYICSR+YRAPELIFG+T+ TT I++WS GCV++E        FPG  S    + +I+KV   P  E ++  +  +Y QF L
Sbjct:   31 ISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLG-FCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSE-LLLGQLIFPG-DSGVDQIVEIVKVMGTPTSE-QLHDMNPHYKQFKL 270          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: MRK1_YEAST (Serine/threonine-protein kinase MRK1 OS=Saccharomyces cerevisiae GN=MRK1 PE=1 SV=2)

HSP 1 Score: 250.751 bits (639), Expect = 9.092e-66
Identity = 126/265 (47.55%), Postives = 176/265 (66.42%), Query Frame = 2

Query:  119 HIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFSTTSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            H   T +  KN      ISY    VVG GSFG+V     +ET + VAIKKVLQDRRYKNREL+ M+++ HPN + L++ F+    ++E++LNLV++Y+P+S+Y+ L+H+ +   +MP + +K Y YQ+F+ L Y+H VPR+CHRD+KPQNLLVDP T   KICDFGSAK L   + N+SYICSR+YRAPEL+FGAT  +  +++WS  CV+AE      P F G +S    L +IIK+   P  + +I  +  NY +  +FP  K
Sbjct:  145 HDRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAE-LLLGKPLFSG-ESGIDQLVEIIKIMGIPTKD-EISGMNPNY-EDHVFPNIK 405          

BLAST of DY304645 vs. ExPASy Swiss-Prot
Match: MDS1_YEAST (Serine/threonine-protein kinase MDS1/RIM11 OS=Saccharomyces cerevisiae GN=MDS1 PE=1 SV=1)

HSP 1 Score: 246.514 bits (628), Expect = 1.715e-64
Identity = 126/248 (50.81%), Postives = 171/248 (68.95%), Query Frame = 2

Query:  170 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFSTTSKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHTVPRVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLIAGEANISYICSRFYRAPELIFGATE*TTSIEIWSPGCVLAEPSFWASP*FPGKKSNWTTLDKIIKVFSYPHPEIKIPFLISNYTQFFLFPRFK 913
            IS+    VVG GSFG+VF     ET E VAIKKVLQD+R+KNREL++M+++ H N+I LK+ F+   S++E++LNL++EY+P+S+Y+ L+H+      M  + +K Y +Q+F+ L Y+H    VCHRD+KPQNLLVDP T  +K+CDFGSAKQL   E N+SYICSR+YRAPELIFGAT  T  I+IWS GCV+AE      P FPG +S    L +IIK+   P  + +I  +  NY +   FP+ K
Sbjct:   37 ISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAE-LLLGQPMFPG-ESGIDQLVEIIKILGTPSKQ-EICSMNPNYME-HKFPQIK 280