FC878149

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_PYRFU (Type II DNA topoisomerase VI subunit A OS=Pyrococcus furiosus GN=top6A PE=3 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 1.435e-35
Identity = 84/280 (30.00%), Postives = 145/280 (51.79%), Query Frame = 1

Query:   31 VQSTIETLILQIARSILAGNGFSFQVPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFY--------TDVKLFQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGVVVGRLTFSDNGDMIDCTKMGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKY 846
            V   +E L  +I   + AG    F VP+R  SN  +  E   I L DK + R F +++  RK   T+ +++ + +L     H + R+ +Y        T    F+DQ++SD +++D+  +LG  R  +++ A  +G V G +   D  D  + +K+GMGG A+P  ++ +   + +  ++L+VE  A   RL E+++  R   +I+  +GQ     R  + ++  E  LP++   D DPYG  I S    GS N++Y S  L TPD K++G+   D+ +Y
Sbjct:   19 VLKKLEDLAYKILEEVKAGKNPYFDVPTRGLSNVYFDEEARLIKLGDKLSRRYFLNVAHARKFMQTLILMAYVKRLVSEGKHASLREAYYANKHTIPGTHENTFEDQSESDPIIEDLERMLGVLREEMHITADRRGYVYGDIVIKDGEDEFNASKLGMGGWAVPGTVEHIQFPEINVDYVLVVETAAMADRLIEEKYPKRERALIIATQGQASRGVRRLIHRLHYEEGLPIIVFTDGDPYGWYIYSTIKQGSINLAYLSEKLATPDAKFVGMTMDDIKEY 298          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_PYRHO (Type II DNA topoisomerase VI subunit A OS=Pyrococcus horikoshii GN=top6A PE=3 SV=2)

HSP 1 Score: 145.976 bits (367), Expect = 2.706e-34
Identity = 82/282 (29.08%), Postives = 145/282 (51.42%), Query Frame = 1

Query:   31 VQSTIETLILQIARSILAGNGFSFQVPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFY--------TDVKLFQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGVVVGRLTFSDNGDMIDCTKMGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKI 852
            V   +E L  +I     +G    F VP+R  +N  +  E   I L D+ + R F +++  RK   T+ +++ I +L     H + R+ +Y        T    F+DQ++SD +++D+  +LG  R  +++ A  +G + G +   D  D  + +K+G GG A+P  ++ +   + +  ++L+VE  A   RL E+++  R  C+IV  +GQ     R  + ++  E  LP++   D DPYG  I S    GS N++Y S  L TPD K++G+   D+ +Y +
Sbjct:   19 VLKKLEDLAWKILEEAKSGKNPYFDVPTRGLNNVYFDEESRLIRLGDRLSRRYFLNVAHARKFMQTLILMAYIKRLVSEGKHASLREAYYANKHTVPGTRENTFEDQSESDPIIEDLERMLGVLREEMHITADRRGYIYGDIVIKDGEDEFNASKLGTGGWAVPGTVEHIQFPEINVDYVLVVETAAMADRLIEEKYPKRENCLIVATQGQASRGVRRLIHRLHYEEGLPIIVFTDGDPYGWYIYSTIKRGSINLAYLSEKLATPDAKFVGMTMDDIKEYNL 300          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_PYRKO (Type II DNA topoisomerase VI subunit A OS=Pyrococcus kodakaraensis GN=top6A PE=3 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 5.643e-32
Identity = 79/271 (29.15%), Postives = 140/271 (51.66%), Query Frame = 1

Query:   61 QIARSILAGNGFSFQVPSRASSNQLYVPELDRIV-LKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFY--------TDVKLFQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGVVVGRLTFSDNGDMIDCTKMGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKY 846
            +I   I AG    F +P R  SN +Y  E  R++ + DK + R F +++  RK   T+ I++ + +L     H + R+ +Y        T    F+DQ++SD +++D+  + G  R  +++ A  +G + G +   D  D  + +++G GG A+P  ++ +   + +  + L+VE  A   RL E++F  R   +I+  +GQ     R  + ++  E  LP++   D DPYG  I S    GS N++Y S  L TP+ K++G+   D+ KY
Sbjct:   32 RILEDIKAGKNPHFDIPMRGLSN-VYFDEKSRLIKMGDKLSRRYFLNVAHARKFMQTLLIMAYVKRLVSEGKHASLREAYYANKHTIPGTRENTFEDQSESDPIIEDLERMFGVLREEMHITADRRGYIYGDIVIRDGEDEFNASRLGSGGWAVPGTVEHIQFPEINVDYALVVETAAMADRLIEEKFPKRENALIIATQGQASRGVRRLIHRLHYEEGLPIIVFTDGDPYGWYIYSTIKQGSINLAYLSDKLATPESKFVGMTMDDIKKY 301          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_METTH (Type II DNA topoisomerase VI subunit A OS=Methanobacterium thermoautotrophicum GN=top6A PE=3 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 1.815e-30
Identity = 84/255 (32.94%), Postives = 127/255 (49.80%), Query Frame = 1

Query:  103 QVPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFYTDVKL---FQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGV-VVGRLTFSDNGDMIDCTKMGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKIP 855
            +VPSR +SN +Y  +    VL D+   R   ++  ++K    +   +    L  R    T R+L+Y        F DQ +S+ V +D+   LG TR  L ++  E G  V G LT  +    ID  + G  G  I P ID V  +  D   ++ VE    + RL +++ Y +F  +IV  KGQ   ATR F++++  EL LPV    D DP+G  I  V   GS  +++ +  L TPD K+LG+  SD+  Y +P
Sbjct:   31 KVPSRGTSNIIYDEDKRHYVLGDRYGTRSMGNVKQIKKIGQMLYTANFCKDLVAREKTATLRELYYISEGWEVDFADQQESNIVGEDLEVTLGMTREELGLMPEEDGASVYGALTVREGDIEIDALRSGKSGYNISPTIDEVEFVDHDVERVIAVETMGMFHRLVQEKAYKKFDALIVGLKGQAARATRRFIKRVNEELNLPVYICNDGDPWGFHIAMVIISGSAKLAHVNHQLATPDAKFLGVTASDIINYDLP 285          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_METJA (Type II DNA topoisomerase VI subunit A OS=Methanocaldococcus jannaschii GN=top6A PE=1 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 1.438e-27
Identity = 92/289 (31.83%), Postives = 143/289 (49.48%), Query Frame = 1

Query:   28 AVQSTIETLILQIARSILAGNGFSFQVPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTI---TVKILSLIHQLCLRNIHVTKRDLFYTDVKL----FQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGV-VVGRLTFSDN---GDMI-DCTKMGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYG-LKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKIP 855
            A Q  IE L  ++   ++ G      +P R+ SN ++  E     L  K   R      TV ++ I   T K+L    QL   +   T R+ +Y         F DQ  S+ V++D+   LG  R  L  I  E G  VVG L   +    G+++ DCTK+G G   IP ++ ++ ++++DA FIL +E    + RL  +RF+++  CI+V+ KG P  ATR F++++  E  LPVL   D DPYG L I      GS    + +  L+ P  + +G+ P D+  Y +P
Sbjct:   15 AKQKIIE-LAKKMYEDLMKGKRPKITMPIRSLSNAMFDKEKGSFTLVGKEKARTL----TVNQAKIFAQTTKMLEFAKQLLETDDFSTLREAYYVSKNWGEARFDDQQASNNVIEDLEAALGVLREHLGFIPEEDGSSVVGPLKIIEETPEGELVVDCTKLGTGAYNIPNDVTKL-NLETDADFILAIETSGMFARLNAERFWDKHNCILVSLKGVPARATRRFIKRLHEEHDLPVLVFTDGDPYGYLNIYRTLKVGSGKAIHLADKLSIPAARLIGVTPQDIIDYDLP 297          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_HALSA (Type II DNA topoisomerase VI subunit A OS=Halobacterium salinarium GN=top6A PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.140e-24
Identity = 82/262 (31.30%), Postives = 126/262 (48.09%), Query Frame = 1

Query:  106 VPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFYTDVKL------FQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGV-VVGRLTFSDN---GDM-IDCTK-MGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKIP 855
            +P+R+ SN  Y  + D  V  D  + R   S+   RK   +V  +  + Q        T R+L+Y           F DQ++SD +++D+  + G  R   ++   E G  V+G L   +    GD  I C + +G GG  IP N D +  + +DA F+L VE      RL E+ F + +  I+V   GQP  ATR   +++  EL LPV    D DP+  +I      GS   ++ S  L TP  +++GIRP D+  Y +P
Sbjct:   37 LPTRSKSNIEYDEDADVWVYGDSQSTRSANSVRGARKLLKSVYTVDFLAQQLDEGRSSTLRELYYLSESWDEAEAQFNDQSESDKLVEDLEIVSGVKREDFHMRPEESGAKVMGPLRLREQTRRGDREIHCQEDVGQGGYQIPNNPDTIDFLDTDADFVLCVETGGMRDRLVENGFDDDYNAIVVHLGGQPARATRRLTKRLHDELDLPVTVFTDGDPWSYRIYGSVAYGSIKSAHLSEYLATPQAQFIGIRPQDIVDYDLP 298          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_HALS3 (Type 2 DNA topoisomerase 6 subunit A OS=Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) GN=top6A PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.140e-24
Identity = 82/262 (31.30%), Postives = 126/262 (48.09%), Query Frame = 1

Query:  106 VPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFYTDVKL------FQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGV-VVGRLTFSDN---GDM-IDCTK-MGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKIP 855
            +P+R+ SN  Y  + D  V  D  + R   S+   RK   +V  +  + Q        T R+L+Y           F DQ++SD +++D+  + G  R   ++   E G  V+G L   +    GD  I C + +G GG  IP N D +  + +DA F+L VE      RL E+ F + +  I+V   GQP  ATR   +++  EL LPV    D DP+  +I      GS   ++ S  L TP  +++GIRP D+  Y +P
Sbjct:   37 LPTRSKSNIEYDEDADVWVYGDSQSTRSANSVRGARKLLKSVYTVDFLAQQLDEGRSSTLRELYYLSESWDEAEAQFNDQSESDKLVEDLEIVSGVKREDFHMRPEESGAKVMGPLRLREQTRRGDREIHCQEDVGQGGYQIPNNPDTIDFLDTDADFVLCVETGGMRDRLVENGFDDDYNAIVVHLGGQPARATRRLTKRLHDELDLPVTVFTDGDPWSYRIYGSVAYGSIKSAHLSEYLATPQAQFIGIRPQDIVDYDLP 298          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_ARCFU (Type II DNA topoisomerase VI subunit A OS=Archaeoglobus fulgidus GN=top6A PE=3 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 1.944e-24
Identity = 76/278 (27.34%), Postives = 133/278 (47.84%), Query Frame = 1

Query:   52 LILQIARSILAGNGFSFQVPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFYTD----VKLFQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGV-VVGRLTFSDNGDM----IDCTK-MGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKIP 855
            ++  I   + AG      + +R   N  +  E +  V  D+ ++R   ++    +      ++  + +    N   T R+L+Y         F++Q +SD +++D+  +    R   ++   E G  V+G L   +        I C   +G GG  IP N+D++  +  DA F++ +E      RL E+ F  ++  IIV  KGQP  +TR  LR++  EL LPV+   D DP+  +I +    GS   ++ S  L TP  +++GIRP+D+ KY +P
Sbjct:   15 IVQNIYDQMKAGQVPELHIATRTKYNIEFNEESEVWVYGDRKSVRSAKTVKGAYRILKMTYVIGFLKEQLNLNKSSTLRELYYISEGWGAAKFEEQPESDRLVEDLEILTNFQREHFHIRPEEDGATVIGPLRVREETRRGVREIHCQDDVGEGGYQIPVNVDKIEFVDHDAKFVIAIETGGMRDRLVENGFDEKYDAIIVHLKGQPARSTRRLLRRLNTELNLPVVVFTDGDPWSYRIFASVAYGSIKSAHLSEYLATPAAQFVGIRPTDIVKYDLP 292          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_METMA (Type II DNA topoisomerase VI subunit A OS=Methanosarcina mazei GN=top6A PE=1 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 3.316e-24
Identity = 80/266 (30.08%), Postives = 133/266 (50.00%), Query Frame = 1

Query:   97 SFQVPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILS----LIHQLCLRNIHVTKRDLFYT----DVKLFQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGVVV-GRLTFSDNGDM----IDCTK-MGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKI 852
            S  +PSR  +N  Y  E D  V  D+ + R   S  TV+ +   +K       LI++   RN   T R+L+Y     D   F++Q +SD +++D+  +    R   ++   E G  + G +  ++        I C K +G GG  IP N++ +   K DA  I+ +E    Y RL E+ F   +  I+V  KGQP  +TR  +++M  EL +PV    D DP+  +I +    G+   ++ S  + TP  K+LG++PSD+ +Y++
Sbjct:   38 SVSLPSRTKANLEYSDESDVWVYGDRESER---SAKTVKGAFQLLKTTYATDFLINEHLARNRGSTLRELYYISEGWDYAKFKEQGESDRLIEDLEILTSLQREYFHMRPEEDGATMFGPIEITEQTKRGERNIHCQKDVGEGGYQIPFNVENIEFQKHDASMIIAIETGGMYARLMENGFDEAYNAILVHLKGQPARSTRRIIKRMNEELGIPVAVFTDGDPWSYRIYASVAYGAIKSAHLSEFMATPAAKFLGLQPSDIVEYEL 300          

BLAST of FC878149 vs. ExPASy Swiss-Prot
Match: TOP6A_NATPD (Type 2 DNA topoisomerase 6 subunit A OS=Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) GN=top6A PE=3 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 5.656e-24
Identity = 77/265 (29.06%), Postives = 132/265 (49.81%), Query Frame = 1

Query:   97 SFQVPSRASSNQLYVPELDRIVLKDKTTLRPFASLSTVRKSTITVKILSLIHQLCLRNIHVTKRDLFYTDVKL------FQDQTQSDAVLDDVACILGCTRSSLNVIAAEKGV-VVGRLTFSDN---GDM-IDCTK-MGMGGKAIPPNIDRVGDMKSDAMFILLVEKDAAYIRLAEDRFYNRFPCIIVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANLTTPDIKWLGIRPSDLDKYKIP 855
            + ++P+R  SN ++  + D  V  D+T+ R   S+   +K    +  +  +     +    T R+L+Y           F DQ +S+ +++D+  +   TR   ++   E G  ++G L   +    G+  I C K +G GG  IP N D +  + +DA F+L VE      RL E+ F      IIV  KGQP  ATR   +++  +L LPV+   D DP+  +I +    GS   ++ S  L TP+ +++GI+P+D+ +Y +P
Sbjct:   36 TMEIPTRTKSNIVFDEDKDVWVYGDRTSTRSANSVRGAQKLLKAIYTIEFLADQLEQGRSSTLRELYYLSESWDEERAQFNDQDESNQLVEDLEIVSKVTREDFHMRPEESGATIMGPLYLREQTRRGEREIHCQKDVGEGGYQIPNNPDTIEFLDNDADFVLCVETGGMRDRLVENGFDEEHNVIIVHLKGQPARATRRITKRLHDDLDLPVVVFCDGDPWSYRIYASVAYGSIKSAHLSEYLATPEAEYIGIQPADIVEYDLP 300