FC920841

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: M3K12_HUMAN (Mitogen-activated protein kinase kinase kinase 12 OS=Homo sapiens GN=MAP3K12 PE=1 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 54/180 (30.00%), Postives = 92/180 (51.11%), Query Frame = 3

Query:  168 GQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLY-GRDRDP---LEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLARWQPDGDMGVETRVLGTFGYLAPEYAQSGQITEKADVYSLGVVLVELITG 695
            G+ VAVK+ +           ++++ L   +H N++   G C +     ++ E+   G L   L  GR   P   ++WS      +G A G+ YLH    +  I+HRD++  N+L+T+D    + DFG ++     D   +    GT  ++APE  ++  ++EK D++S GVVL EL+TG
Sbjct:  146 GEEVAVKKVRDLKE-------TDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWS------MGIAGGMNYLH----LHKIIHRDLKSPNMLITYDDVVKISDFGTSKEL--SDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 306          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: LRRK2_MOUSE (Leucine-rich repeat serine/threonine-protein kinase 2 OS=Mus musculus GN=Lrrk2 PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 65/197 (32.99%), Postives = 108/197 (54.82%), Query Frame = 3

Query:  120 LAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFE-----PLVGDFGLARWQPDGDMGVETRVLGTFGYLAPEYAQSGQI-TEKADVYSLGVVLVELIT 692
            L +G F SV+R    +G+ VAVK +   +S   +    E+ VL    H +++ L+   +    R+LV E    GSLD  L  +D+  L  + + +IA+  A GLRYLH       I++RD++P+N+L+   +        + D+G+A++     MG++T   GT G+ APE A+   I  ++ADVYS G++L ++ T
Sbjct: 1885 LGDGSFGSVYRAAY-EGEEVAVKIFNKHTSL--RLLRQELVVLCHLHHPSLISLLAAGIRP--RMLVMELASKGSLD-RLLQQDKASLTRTLQHRIALHVADGLRYLHS----AMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQY--CCRMGIKTSE-GTPGFRAPEVARGNVIYNQQADVYSFGLLLHDIWT 2068          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: LCK_RAT (Proto-oncogene tyrosine-protein kinase LCK OS=Rattus norvegicus GN=Lck PE=2 SV=3)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 67/227 (29.52%), Postives = 97/227 (42.73%), Query Frame = 3

Query:   12 LCSTCQHKAPVFGNPPRWFTYAELELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLARWQPDGDMGVETRVLGTFGYLAPEYAQSGQITEKADVYSLGVVLVELIT 692
            L   CQ + P     P W    E+   T +  E   L  G F  V  G       VAVK  K  S   D  F +E  ++   QH  +V L     ++   ++  EY+ NGSL   L       L  +    +A   A G+ ++ E+      +HRD+R  NILV+      + DFGLAR   D +            + APE    G  T K+DV+S G++L E++T
Sbjct:  220 LSRPCQTQKP---QKPWWEDEWEVPRETLKLVER--LGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA-FLAEANLMKQLQHPRLVRLYAVVTQEPIYIIT-EYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEGMAFIEEQN----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 435          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: LCK_MOUSE (Proto-oncogene tyrosine-protein kinase LCK OS=Mus musculus GN=Lck PE=1 SV=4)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 67/227 (29.52%), Postives = 97/227 (42.73%), Query Frame = 3

Query:   12 LCSTCQHKAPVFGNPPRWFTYAELELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLARWQPDGDMGVETRVLGTFGYLAPEYAQSGQITEKADVYSLGVVLVELIT 692
            L   CQ + P     P W    E+   T +  E   L  G F  V  G       VAVK  K  S   D  F +E  ++   QH  +V L     ++   ++  EY+ NGSL   L       L  +    +A   A G+ ++ E+      +HRD+R  NILV+      + DFGLAR   D +            + APE    G  T K+DV+S G++L E++T
Sbjct:  220 LSRPCQTQKP---QKPWWEDEWEVPRETLKLVER--LGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA-FLAEANLMKQLQHPRLVRLYAVVTQEPIYIIT-EYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEGMAFIEEQN----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 435          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: LCK_HUMAN (Proto-oncogene tyrosine-protein kinase LCK OS=Homo sapiens GN=LCK PE=1 SV=6)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 67/227 (29.52%), Postives = 97/227 (42.73%), Query Frame = 3

Query:   12 LCSTCQHKAPVFGNPPRWFTYAELELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLARWQPDGDMGVETRVLGTFGYLAPEYAQSGQITEKADVYSLGVVLVELIT 692
            L   CQ + P     P W    E+   T +  E   L  G F  V  G       VAVK  K  S   D  F +E  ++   QH+ +V L     ++   ++  EY+ NGSL   L       L  +    +A   A G+ ++ E       +HRD+R  NILV+      + DFGLAR   D +            + APE    G  T K+DV+S G++L E++T
Sbjct:  220 LSRPCQTQKP---QKPWWEDEWEVPRETLKLVER--LGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA-FLAEANLMKQLQHQRLVRLYAVVTQEPIYIIT-EYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERN----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 435          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: KRAF1_CAEBR (Raf homolog serine/threonine-protein kinase OS=Caenorhabditis briggsae GN=lin-45 PE=3 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 64/224 (28.57%), Postives = 112/224 (50.00%), Query Frame = 3

Query:   54 PPRWFTYAELELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQ--EFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRD-RDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPL-VGDFGLA----RWQPDGDMGVETRVLGTFGYLAPEYAQ---SGQITEKADVYSLGVVLVELIT 692
            PP+   + + E+  N F     +  G F +V+RG       VA+K+  +      Q   F +EV VL   +H NV++ +G+ V +    ++ ++    SL  H++ ++ R   E SA   I    + G+ YLH +     I+HRD++ NNI +  D   + +GDFGLA    +W  +G    + +  G+  ++APE  +       T ++DVYS GV + E+++
Sbjct:  463 PPQKPQHEDWEILPNEFVIHYKVGSGSFGTVYRGEFFG--TVAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLLFMGW-VREPEIAIITQWCEGSSLYRHIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSKN----IIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQ-QQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEILS 678          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: FGR_MOUSE (Proto-oncogene tyrosine-protein kinase Fgr OS=Mus musculus GN=Fgr PE=1 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 62/203 (30.54%), Postives = 90/203 (44.33%), Query Frame = 3

Query:   84 ELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLARWQPDGDMGVETRVLGTFGYLAPEYAQSGQITEKADVYSLGVVLVELIT 692
            E+  N  +    L  G F  V  G       VAVK  K   +   + F  E +++   +H  +V L     E+    +V E++C GSL   L  R+   L       +A   A G+ Y+         +HRD+R  NILV       + DFGLAR   D +   +        + APE A  G+ T K+DV+S G++L ELIT
Sbjct:  245 EIDRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLK-PGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPI-YIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMN----YIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELIT 441          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: BRAF1_MOUSE (B-Raf proto-oncogene serine/threonine-protein kinase OS=Mus musculus GN=Braf PE=1 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 59/212 (27.83%), Postives = 99/212 (46.70%), Query Frame = 3

Query:   84 ELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLA----RWQPDGDMGVETRVLGTFGYLAPEYAQ---SGQITEKADVYSLGVVLVELITGR 698
            E+   + +    +  G F +V++G       V +      + Q  Q F +EV VL   +H N+++ +G+  +   +L +    C GS   H         E      IA   A+G+ YLH +     I+HRD++ NNI +  D    +GDFGLA    RW          ++ G+  ++APE  +       + ++DVY+ G+VL EL+TG+
Sbjct:  488 EIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKP--QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS----IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF---EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 690          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: BRAF1_HUMAN (B-Raf proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=BRAF PE=1 SV=4)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 59/212 (27.83%), Postives = 99/212 (46.70%), Query Frame = 3

Query:   84 ELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLA----RWQPDGDMGVETRVLGTFGYLAPEYAQ---SGQITEKADVYSLGVVLVELITGR 698
            E+   + +    +  G F +V++G       V +      + Q  Q F +EV VL   +H N+++ +G+  +   +L +    C GS   H         E      IA   A+G+ YLH +     I+HRD++ NNI +  D    +GDFGLA    RW          ++ G+  ++APE  +       + ++DVY+ G+VL EL+TG+
Sbjct:  451 EIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKP--QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS----IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF---EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 653          

BLAST of FC920841 vs. ExPASy Swiss-Prot
Match: BRAF1_COTJA (B-Raf proto-oncogene serine/threonine-protein kinase OS=Coturnix coturnix japonica GN=BRAF PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 6.197e-14
Identity = 59/212 (27.83%), Postives = 99/212 (46.70%), Query Frame = 3

Query:   84 ELATNRFSEANFLAEGGFVSVHRGVLPDGQVVAVKQYKLASSQGDQEFCSEVEVLSCAQHRNVVMLIGFCVEDGRRLLVYEYICNGSLDSHLYGRDRDPLEWSARRKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILVTHDFEPLVGDFGLA----RWQPDGDMGVETRVLGTFGYLAPEYAQ---SGQITEKADVYSLGVVLVELITGR 698
            E+   + +    +  G F +V++G       V +      + Q  Q F +EV VL   +H N+++ +G+  +   +L +    C GS   H         E      IA   A+G+ YLH +     I+HRD++ NNI +  D    +GDFGLA    RW          ++ G+  ++APE  +       + ++DVY+ G+VL EL+TG+
Sbjct:  491 EIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKP--QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS----IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF---EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 693