FC930987

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: MP2K6_MOUSE (Dual specificity mitogen-activated protein kinase kinase 6 OS=Mus musculus GN=Map2k6 PE=2 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 50/157 (31.85%), Postives = 76/157 (48.41%), Query Frame = 1

Query:  136 ARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQAHSVIGTPEFMAPE-----LYEEDYNELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGKLPGAFHRIQDAEARRFVGKCLENVSKRLPA-KELLLDPF 588
            A  I++ + +LH     VIHRD+K  N+ +N  LGQ+K+ D G++  L  S       G   +MAPE     L ++ Y+   DI+S G+ ++E+    +PY     P Q  K+V     P        A+   F  +CL+  SK  P   EL+  PF
Sbjct:  159 AVSIVKALEHLHSK-LSVIHRDVKPSNVLINT-LGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPF 313          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: MP2K6_BOVIN (Dual specificity mitogen-activated protein kinase kinase 6 OS=Bos taurus GN=MAP2K6 PE=2 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 50/157 (31.85%), Postives = 75/157 (47.77%), Query Frame = 1

Query:  136 ARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQAHSVIGTPEFMAPE-----LYEEDYNELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGKLPGAFHRIQDAEARRFVGKCLENVSKRLPA-KELLLDPF 588
            A  I++ + +LH     VIHRD+K  N+ +N  LGQ+K+ D G++  L  S       G   +MAPE     L ++ Y+   DI+S G+ ++E+    +PY     P Q  K+V     P         E   F  +CL+  SK  P   EL+  PF
Sbjct:  159 AVSIVKALEHLHSK-LSVIHRDVKPSNVLINA-LGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSKERPTYPELMQHPF 313          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: MOM4_CAEBR (Mitogen-activated protein kinase kinase kinase mom-4 OS=Caenorhabditis briggsae GN=mom-4 PE=3 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 48/164 (29.27%), Postives = 79/164 (48.17%), Query Frame = 1

Query:    1 IRFYASWIDVDRRTFNFITEMFTSGTLRE--YRKKYTRVDIRAVKNWARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQAHSVIGTPEFMAPELYE-EDYNELVDIYSFGMCVLEMLTSDYPYS-ECSNPAQIYKKVTSGKLP 480
            I+ Y  + D  R     + E    G++ E  Y +K     I  V +W  Q+   +   H +D   +HRDLK  N+ +      +K+ D G    +  S  ++   GTP  MAPE++  E+YN+  DIYS G+ + +M+  ++PY+   S P  +Y   T+   P
Sbjct:  113 IKIYGLYRDA-RHGQGVVMEYMDCGSMSELIYDRKSIDYTIDHVASWLYQMASAVNTFHRNDQ--VHRDLKLQNMLLCDRYRTMKLCDFGTFTAMHQSMTSNR--GTPITMAPEVFRCEEYNQKSDIYSIGIIMWQMIARNHPYNRNLSVPGLLYNVATASLRP 271          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: MARK4_MOUSE (MAP/microtubule affinity-regulating kinase 4 OS=Mus musculus GN=Mark4 PE=1 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 48/189 (25.40%), Postives = 99/189 (52.38%), Query Frame = 1

Query:   37 RTFNFITEMFTSGTLREYRKKYTRVDIRAVKNWARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQAHSVIGTPEFMAPELYE-EDYN-ELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGKLPGAFHRIQDAEA--RRFVGKCLENVSKRLPAKELLLDPFL 591
            +T   + E  ++G + +Y   + R+  +  +   RQI+  + Y H  +  ++HRDLK +N+ ++     IKI D G +       +  +  G+P + APEL++ + Y+   VDI+S G+ +  +++   P+ +  N  ++ ++V  GK    F+   D E+  RRF+   + N +KR   ++++ D ++
Sbjct:  129 KTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN--IVHRDLKAENLLLDAE-ANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPF-DGHNLKELRERVLRGKYRVPFYMSTDCESILRRFL---VLNPAKRCTLEQIMKDKWI 310          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: MARK4_HUMAN (MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 48/189 (25.40%), Postives = 99/189 (52.38%), Query Frame = 1

Query:   37 RTFNFITEMFTSGTLREYRKKYTRVDIRAVKNWARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQAHSVIGTPEFMAPELYE-EDYN-ELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGKLPGAFHRIQDAEA--RRFVGKCLENVSKRLPAKELLLDPFL 591
            +T   + E  ++G + +Y   + R+  +  +   RQI+  + Y H  +  ++HRDLK +N+ ++     IKI D G +       +  +  G+P + APEL++ + Y+   VDI+S G+ +  +++   P+ +  N  ++ ++V  GK    F+   D E+  RRF+   + N +KR   ++++ D ++
Sbjct:  129 KTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN--IVHRDLKAENLLLDAE-ANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPF-DGHNLKELRERVLRGKYRVPFYMSTDCESILRRFL---VLNPAKRCTLEQIMKDKWI 310          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: E2AK3_CAEEL (Eukaryotic translation initiation factor 2-alpha kinase OS=Caenorhabditis elegans GN=pek-1 PE=1 SV=2)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 59/202 (29.21%), Postives = 95/202 (47.03%), Query Frame = 1

Query:   52 ITEMFTSGTLREYRKKYTRVDIR---AVKNWARQILRGIAYLHGHDPPVIHRDLKCDNIF-----VNGHLGQIKIGDLGLAAILRG-----------SQQAHSV-IGTPEFMAPE-LYEEDYNELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGKLPGAFHRIQDAEARRFVGKCLE-NVSKRLPAKELLLDPFL 591
            + ++    TL ++ ++   ++ R    +KNW +Q+  G+ YL  H+   IHRDLK  N+F      +GH   +KIGDLGLA    G           S   H+  +GT  +M+PE L  + Y E VDI++ G+   E++ S   +S  S     +     G +P     +   E+R F+ +      S+R  A E+    FL
Sbjct:  883 VMQLCAEKTLEDWIRRSKTMESRPLFTMKNWIKQLASGLEYL--HNKGFIHRDLKPGNVFFSLDSTHGH-QILKIGDLGLATKTDGAPKITVRQDSDSSAKHTKNVGTRSYMSPEQLKHQQYTEKVDIFALGLVATELIIS---FSTASERIHTFADFQKGDIPAILDNV--PESRDFLLQLTSLEPSERPTAHEVATHKFL 1076          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: CRK38_ARATH (Cysteine-rich receptor-like protein kinase 38 OS=Arabidopsis thaliana GN=CRK38 PE=2 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 60/183 (32.79%), Postives = 89/183 (48.63%), Query Frame = 1

Query:  145 ILRGIAYLHGHDP-PVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQ---AHSVIGTPEFMAPE-LYEEDYNELVDIYSFGMCVLEMLT--SDYPYSECSN-PAQIYKKVTSGK----LPGAFHRIQDAEARRFVGKCL----ENVSKRLPAKELLLDPFLASDAGEPLLIPQVPSFQN 645
            + RG+ YLH      +IHRDLK  NI ++ ++   K+ D G+A +    Q       V+GT  +MAPE +    ++   D+YSFG+ +LEM+T  S+  Y E    PA  +K   +G+    +     R +  E  RF+   L    ENVSKR P   L++    +     PL  P V  F N
Sbjct:  445 VARGLVYLHEDSQLRIIHRDLKASNILLDAYMNP-KVADFGMARLFNMDQTRAVTRKVVGTFGYMAPEYVRNRTFSVKTDVYSFGVVLLEMITGRSNKNYFEALGLPAYAWKCWVAGEAASIIDHVLSRSRSNEIMRFIHIGLLCVQENVSKR-PTMSLVIQWLGSETIAIPL--PTVAGFTN 623          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: CHK2_MOUSE (Serine/threonine-protein kinase Chk2 OS=Mus musculus GN=Chek2 PE=2 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 56/200 (28.00%), Postives = 95/200 (47.50%), Query Frame = 1

Query:   31 DRRTFNFITEMFTSGTLREYRKKYTRVDIRAVKNWARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQ--IKIGDLGLAAILRGSQQAHSVIGTPEFMAPELYEED----YNELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGK---LPGAFHRIQDAEARRFVGKCL-ENVSKRLPAKELLLDPFLASD 600
            D   +  + E+   G L +      R+     K +  Q+L  + YLH +   +IHRDLK +N+ ++       IKI D G + IL  +    ++ GTP ++APE+   +    Y+  VD +S G+ +   L+   P+SE      +  ++TSGK   +P  +  + + EA   V K L  +   RL  +E L  P+L  +
Sbjct:  297 DAEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENG--IIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSE-EALDLVKKLLVVDPKARLTTEEALNHPWLQDE 493          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: CDK6_HUMAN (Cell division protein kinase 6 OS=Homo sapiens GN=CDK6 PE=1 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 61/186 (32.80%), Postives = 81/186 (43.55%), Query Frame = 1

Query:  109 VDIRAVKNWARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQAHSVIGTPEFMAPE-LYEEDYNELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGKLPG-------------AFHRIQDAEARRFVG-----------KCLE-NVSKRLPAKELLLDPF 588
            V    +K+   Q+LRG+ +LH H   V+HRDLK  NI V    GQIK+ D GLA I        SV+ T  + APE L +  Y   VD++S G    EM      +   S+  Q+ K +    LPG             AFH        +FV            KCL  N +KR+ A   L  P+
Sbjct:  117 VPTETIKDMMFQLLRGLDFLHSHR--VVHRDLKPQNILVTSS-GQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPY 299          

BLAST of FC930987 vs. ExPASy Swiss-Prot
Match: AUR1_ARATH (Serine/threonine-protein kinase Aurora-1 OS=Arabidopsis thaliana GN=AUR1 PE=2 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.342e-11
Identity = 52/193 (26.94%), Postives = 93/193 (48.19%), Query Frame = 1

Query:   31 DRRTFNFITEMFTSGTLREYRKKYTRVDIRAVKNWARQILRGIAYLHGHDPPVIHRDLKCDNIFVNGHLGQIKIGDLGLAAILRGSQQAHSVIGTPEFMAPELYEE-DYNELVDIYSFGMCVLEMLTSDYPYSECSNPAQIYKKVTSGKLPGAFHRIQDAEARRFVGKCL-ENVSKRLPAKELLLDPFLASDA 603
            D++    I E    G L +  +K      R    +   + R + Y HG    VIHRD+K +N+ + G  G++KI D G +  +    +  ++ GT +++ PE+ E  +++  VDI+S G+   E L    P+ E    +  Y+++    L      I  A A+  + + L +  S+RLP  +LL  P++  +A
Sbjct:  100 DQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKH--VIHRDIKPENLLI-GAQGELKIADFGWS--VHTFNRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPF-EAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLVKESSQRLPLHKLLEHPWIVQNA 286