FC931797

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: AAPK1_CAEEL (5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Caenorhabditis elegans GN=aak-1 PE=2 SV=2)

HSP 1 Score: 185.267 bits (469), Expect = 2.849e-46
Identity = 92/181 (50.83%), Postives = 123/181 (67.96%), Query Frame = 1

Query:   22 VSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDG-LLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCP 558
            V+  + EI  +++L HPHI +L+ V++T S I+ VME V GGELF+ I  KG      SR+Y QQ++S V YCH+  + HRDLKPENLLLD N N+K++DFGLS       TDG LL T CG+P Y APE++S K Y G +VDLWSCGVIL+ +  G LPF+D N+ +++ KI  G +  P
Sbjct:   66 VNKTRNEIDNLQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLS----NYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVP 242          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: MELK_HUMAN (Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3)

HSP 1 Score: 184.882 bits (468), Expect = 3.721e-46
Identity = 95/194 (48.97%), Postives = 131/194 (67.53%), Query Frame = 1

Query:    1 KIMSSNLVSN----IKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKI-AKGRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            KIM  N + +    IK EI  ++ L H HI +LY VL T +KI+ V+E+  GGELF  I ++ R SE+ +R   +Q+VSAV Y HS+G  HRDLKPENLL DE   LK+ DFGL A K +   D  L T CG+ AY APE++  K Y G++ D+WS G++L+VL  G+LPF+D N+M++YKKI +G++  PKW+
Sbjct:   40 KIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCA-KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWL 232          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: SNF1_CANAL (Carbon catabolite-derepressing protein kinase OS=Candida albicans GN=SNF1 PE=2 SV=2)

HSP 1 Score: 176.792 bits (447), Expect = 1.084e-45
Identity = 91/191 (47.64%), Postives = 132/191 (69.11%), Query Frame = 1

Query:    4 IMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDG-LLHTLCGTPAYV-APEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            +  S++   ++REIS +R L HPHI+KLY+V+ +K +I  V+EF  G ELF  I  +G+  ED +R++ QQ+++AV YCH   + HRDLKPENLLLD+  N+K++DFGLS     I TDG  L T CG+P Y+ APE++S K Y G +VD+WS GVIL+V+  G LPF+D  + +++KKI  G +  P ++
Sbjct:   89 LAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLS----NIMTDGNFLKTSCGSPNYMPAPEVISGKLYAGPEVDVWSAGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYL 274          

HSP 2 Score: 28.1054 bits (61), Expect = 1.084e-45
Identity = 10/19 (52.63%), Postives = 14/19 (73.68%), Query Frame = 3

Query:  609 NPETRITVDQIIHDPWFKK 665
            NP  RIT+ +I+ D WFK+
Sbjct:  289 NPLNRITIHEIMEDDWFKQ 307          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: AMPKA_DICDI (5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha OS=Dictyostelium discoideum GN=snfA PE=2 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 1.410e-45
Identity = 93/191 (48.69%), Postives = 126/191 (65.97%), Query Frame = 1

Query:    1 KIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIAK-GRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDE-NGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            KI +  +   I+REI  M+   HPHI+KLYEV+ T + I+ VME+V GGELF  I K G+  ED SR+  QQ++S V YCH   V HRDLKPENLLLD  N  +K++DFGLS   + ++    L T CG+P Y APE++S K Y G +VD+WSCGVIL+      LPF+D ++  ++KKI +G F  P ++
Sbjct:   66 KIKNLKMDEKIRREIQNMKLFRHPHIIKLYEVIETTTDIFMVMEYVTGGELFEYIVKNGKLLEDESRRLFQQMISGVDYCHHHMVVHRDLKPENLLLDPINKCIKIADFGLS---NMMQDGDFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYAFLCAKLPFDDESIPMLFKKIREGVFSIPDFV 253          

HSP 2 Score: 23.483 bits (49), Expect = 1.410e-45
Identity = 8/18 (44.44%), Postives = 13/18 (72.22%), Query Frame = 3

Query:  609 NPETRITVDQIIHDPWFK 662
            +P  RIT+ +I + PWF+
Sbjct:  268 DPVKRITIHEIRNHPWFQ 285          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: SIK2_MOUSE (Serine/threonine-protein kinase SIK2 OS=Mus musculus GN=Sik2 PE=1 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 3.150e-45
Identity = 87/183 (47.54%), Postives = 124/183 (67.76%), Query Frame = 1

Query:   22 VSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIAK-GRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            +  I RE+ IM+ L+HPHI+KLY+V+ TKS +Y V E+ K GE+F  +A  GR +E  +R+   Q++SAV YCH R V HRDLK ENLLLD N N+K++DFG     +  +T  LL T CG+P Y APE+   + Y+G ++D+WS GV+L+VL  G LPF+ P L  + +++ +G FR P +M
Sbjct:   61 LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFG---NFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM 240          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: SNF1_SCHPO (SNF1-like protein kinase ssp2 OS=Schizosaccharomyces pombe GN=ssp2 PE=1 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 4.077e-45
Identity = 87/190 (45.79%), Postives = 130/190 (68.42%), Query Frame = 1

Query:    4 IMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDG-LLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            +  S++   ++REIS ++ L HPHI+KLY+V+ T + I  V+E+  GGELF  I  K R +ED  R++ QQ++ A+ YCH   + HRDLKPENLLLD+N N+K++DFGLS     I TDG  L T CG+P Y APE+++ K Y G +VD+WSCG++L+V+  G LPF+D  + +++KK+    +  P ++
Sbjct:   70 LKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLS----NIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFL 254          

HSP 2 Score: 25.7942 bits (55), Expect = 4.077e-45
Identity = 9/17 (52.94%), Postives = 12/17 (70.59%), Query Frame = 3

Query:  609 NPETRITVDQIIHDPWF 659
            +P  RIT+ +I  DPWF
Sbjct:  269 DPMQRITIQEIRRDPWF 285          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: SIK2_CHICK (Serine/threonine-protein kinase SIK2 OS=Gallus gallus GN=SIK2 PE=2 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 7.017e-45
Identity = 90/186 (48.39%), Postives = 124/186 (66.67%), Query Frame = 1

Query:   13 SNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKI-AKGRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            SNL   I RE+ IM+ LNHPHI+KLY+V+ TK  +Y V EF K GE+F  + + G  SE  +RK   Q++SAV YCHS  + HRDLK ENLLLD N N+K++DFG     +  ++   L T CG+P Y APE+   K Y+G  +D+WS GV+L+VL  G LPF+ PNL ++ +++ +G FR P +M
Sbjct:   65 SNL-EKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLADFGFG---NFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFM 246          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: MARK2_HUMAN (Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2)

HSP 1 Score: 177.948 bits (450), Expect = 1.172e-44
Identity = 86/188 (45.74%), Postives = 127/188 (67.55%), Query Frame = 1

Query:    7 MSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAK-IAKGRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            ++S+ +  + RE+ IM+ LNHP+IVKL+EV+ T+  +Y VME+  GGE+F   +A GR  E  +R   +Q+VSAV YCH + + HRDLK ENLLLD + N+K++DFG S   ++      L T CG+P Y APE+   K YDG +VD+WS GVIL+ L +G LPF+  NL  + +++ +G++R P +M
Sbjct:   89 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFS---NEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYM 273          

HSP 2 Score: 23.483 bits (49), Expect = 1.172e-44
Identity = 9/20 (45.00%), Postives = 12/20 (60.00%), Query Frame = 3

Query:  609 NPETRITVDQIIHDPWFKKG 668
            NP  R T++QI+ D W   G
Sbjct:  288 NPSKRGTLEQIMKDRWMNVG 307          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: MARK2_RAT (Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus GN=Mark2 PE=1 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 1.173e-44
Identity = 86/188 (45.74%), Postives = 127/188 (67.55%), Query Frame = 1

Query:    7 MSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAK-IAKGRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            ++S+ +  + RE+ IM+ LNHP+IVKL+EV+ T+  +Y VME+  GGE+F   +A GR  E  +R   +Q+VSAV YCH + + HRDLK ENLLLD + N+K++DFG S   ++      L T CG+P Y APE+   K YDG +VD+WS GVIL+ L +G LPF+  NL  + +++ +G++R P +M
Sbjct:   89 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFS---NEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYM 273          

HSP 2 Score: 23.483 bits (49), Expect = 1.173e-44
Identity = 9/20 (45.00%), Postives = 12/20 (60.00%), Query Frame = 3

Query:  609 NPETRITVDQIIHDPWFKKG 668
            NP  R T++QI+ D W   G
Sbjct:  288 NPSKRGTLEQIMKDRWMNVG 307          

BLAST of FC931797 vs. ExPASy Swiss-Prot
Match: SIK2_HUMAN (Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 1.197e-44
Identity = 85/183 (46.45%), Postives = 124/183 (67.76%), Query Frame = 1

Query:   22 VSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIAK-GRFSEDLSRKYLQQLVSAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNLMSMYKKIYKGEFRCPKWM 567
            +  I RE+ IM+ L+HPHI+KLY+V+ TKS +Y V E+ K GE+F  +A  GR +E  +R+   Q++SAV YCH R + HRDLK ENLLLD N N+K++DFG     +  ++  LL T CG+P Y APE+   + Y+G ++D+WS GV+L+VL  G LPF+ P L  + +++ +G FR P +M
Sbjct:   61 LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFG---NFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM 240