GH733292

BLAST of GH733292 vs. ExPASy Swiss-Prot
Match: TOP1_CAEEL (DNA topoisomerase 1 OS=Caenorhabditis elegans GN=top-1 PE=2 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 1.230e-13
Identity = 35/85 (41.18%), Postives = 56/85 (65.88%), Query Frame = -1

Query:   31 KGKPPLMKDSDG--KRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 279
            K K   +K+++   K  R    E  ++K  +   +++K++     K++ K +ALGTSK+NY+DPRITVAWCK+ EVP+EK+F K+
Sbjct:  701 KDKKKEVKEAEAALKSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKT 785          

BLAST of GH733292 vs. ExPASy Swiss-Prot
Match: TOP1_SCHPO (DNA topoisomerase 1 OS=Schizosaccharomyces pombe GN=top1 PE=1 SV=2)

HSP 1 Score: 71.2478 bits (173), Expect = 1.777e-12
Identity = 32/64 (50.00%), Postives = 48/64 (75.00%), Query Frame = -1

Query:   28 EALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 219
            E LE+++ + N +I  M   M  K++ KT ALGTSKINY+DPR+T ++ KR +VPIEK+F+K++
Sbjct:  735 EQLEKRLNKLNERINVMRTQMIDKDENKTTALGTSKINYIDPRLTYSFSKREDVPIEKLFSKTI 798          

BLAST of GH733292 vs. ExPASy Swiss-Prot
Match: TOP1M_PANTR (DNA topoisomerase I, mitochondrial OS=Pan troglodytes GN=TOP1MT PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 3.958e-12
Identity = 34/73 (46.58%), Postives = 49/73 (67.12%), Query Frame = -1

Query:   31 DGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 249
            DGK +  L  E   R + +   ++ ++      KE+ K VALGTSK+NYLDPRI++AWCKR  VP+EKI++K+
Sbjct:  513 DGKSRSVL--EKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKT 583          

BLAST of GH733292 vs. ExPASy Swiss-Prot
Match: TOP1M_MOUSE (DNA topoisomerase I, mitochondrial OS=Mus musculus GN=Top1mt PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 3.958e-12
Identity = 35/84 (41.67%), Postives = 53/84 (63.10%), Query Frame = -1

Query:   31 KKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 282
            +K +  L    D K K  L  +   R++ +   ++ ++      KE+ K VALGT+K+NYLDPRI++AWCKR  VP+EKI+NK+
Sbjct:  495 QKAETDLRMRGDSKPKSFLQKQ---RRLLKLEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKT 575          

BLAST of GH733292 vs. ExPASy Swiss-Prot
Match: TOP1M_HUMAN (DNA topoisomerase I, mitochondrial OS=Homo sapiens GN=TOP1MT PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 3.958e-12
Identity = 34/73 (46.58%), Postives = 49/73 (67.12%), Query Frame = -1

Query:   31 DGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 249
            DGK +  L  E   R + +   ++ ++      KE+ K VALGTSK+NYLDPRI++AWCKR  VP+EKI++K+
Sbjct:  513 DGKSRSVL--EKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKT 583          

BLAST of GH733292 vs. ExPASy Swiss-Prot
Match: TOP1M_RAT (DNA topoisomerase I, mitochondrial OS=Rattus norvegicus GN=Top1mt PE=2 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 5.169e-12
Identity = 37/84 (44.05%), Postives = 52/84 (61.90%), Query Frame = -1

Query:   31 KKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS 282
            +K +  L    D K K  L  +    K+ +  A++     D   KE+ K VALGT+K+NYLDPRI++AWCKR  VP+EKI+NK+
Sbjct:  495 QKAETDLRMRGDSKSKSFLQKQQRLLKLEEQLARLCTKATD---KEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKT 575          

BLAST of GH733292 vs. ExPASy Swiss-Prot
Match: TOP1_YEAST (DNA topoisomerase 1 OS=Saccharomyces cerevisiae GN=TOP1 PE=1 SV=2)

HSP 1 Score: 67.0106 bits (162), Expect = 3.351e-11
Identity = 29/64 (45.31%), Postives = 47/64 (73.44%), Query Frame = -1

Query:   28 EALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSL 219
            E ++ ++ +   +I+     +K KE+   V+LGTSKINY+DPR++V +CK+++VPIEKIF K+L
Sbjct:  689 EKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTL 752