CB250328

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: JAK2_HUMAN (Tyrosine-protein kinase JAK2 OS=Homo sapiens GN=JAK2 PE=1 SV=2)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 39/106 (36.79%), Postives = 60/106 (56.60%), Query Frame = 1

Query:  289 KQFNREVALLSRLHNPNVIKFVAACKKPPV--YCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGI 600
            + F RE+ +L  L + N++K+   C         +I EYL  GSLR YL K + +   + KL+     I +GMEY+ ++  IHRDL   N+L++ E  +KI DFG+
Sbjct:  893 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHI-KLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGL 997          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: IGF1R_MOUSE (Insulin-like growth factor 1 receptor OS=Mus musculus GN=Igf1r PE=1 SV=3)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 48/175 (27.43%), Postives = 86/175 (49.14%), Query Frame = 1

Query:  124 DEHTVDLSQLFLGLRFAHGAHSRLYHGI----YKDEP---VAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKT-------LP--LPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGI 600
            DE  V   ++ +      G+   +Y G+     KDEP   VA+K +       NE  + R   +F  E +++   +  +V++ +    +     VI E ++ G L++YL  L  +        +P  L K+I +A +IA GM Y+++   +HRDL   N ++ ++F +KI DFG+
Sbjct:  991 DEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTV-------NEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGM 1158          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: EPHA3_HUMAN (Ephrin type-A receptor 3 OS=Homo sapiens GN=EPHA3 PE=1 SV=2)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 40/160 (25.00%), Postives = 79/160 (49.38%), Query Frame = 1

Query:  124 DEHTVDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            D   + + ++     F      RL     K+  VA+K +++   ++         + F  E +++ +  +PN+I+      K     ++TEY+  GSL ++L K + +   + +L+ +   IA GM+Y+   G +HRDL   N+LI+     K++DFG++
Sbjct:  617 DATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQR-------RDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVI-QLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLS 768          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: CRK25_ARATH (Cysteine-rich receptor-like protein kinase 25 OS=Arabidopsis thaliana GN=CRK25 PE=2 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 57/200 (28.50%), Postives = 97/200 (48.50%), Query Frame = 1

Query:   43 RYKSRKESAWTKYFDHGGV--------RVNAVDAADEHTVDLSQLFLGLRFAHGAHSRLYHG-IYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLE-HKTLPLPKLIAIALDIARGMEYIHSQG---VIHRDLKPENVLIDQEFHLKIADFGIA 603
            R ++ K SA T+  D  G+        + +A++AA     + ++L       HG    +Y G +   E VA+K +      +  T  A   ++F  EV ++++L + N+ K +  C       ++ E++   SL  +L   E  + L   +   I   IARG+ Y+H      +IHRDLK  N+L+D + H KI+DFG+A
Sbjct:  309 RRRNNKLSAETEDLDEDGITSTETLQFQFSAIEAATNKFSESNKL------GHGGFGEVYKGQLITGETVAIKRL-----SQGSTQGA---EEFKNEVDVVAKLQHRNLAKLLGYCLDGEEKILVYEFVPNKSLDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHRDSRLTIIHRDLKASNILLDADMHPKISDFGMA 494          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: CIPK2_ARATH (CBL-interacting serine/threonine-protein kinase 2 OS=Arabidopsis thaliana GN=CIPK2 PE=1 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 45/152 (29.61%), Postives = 82/152 (53.95%), Query Frame = 1

Query:  157 LGLRFAHGAHSRLYHGI--YKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIK-FVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            +G     G  +++Y G   + +E VA+K+I     D+++ +   L +Q  RE++++    +PNV++ +     K  +Y VI EY   G L    +K+    L           +   +++ HS+GV HRD+KPEN+L+D   +LK++DFG++
Sbjct:   14 VGRLLGQGTFAKVYFGRSNHTNESVAIKMI-----DKDKVMRVGLSQQIKREISVMRIAKHPNVVELYEVMATKSRIYFVI-EYCKGGEL---FNKVAKGKLKEDVAWKYFYQLISAVDFCHSRGVYHRDIKPENLLLDDNDNLKVSDFGLS 156          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: CDK3_HUMAN (Cell division protein kinase 3 OS=Homo sapiens GN=CDK3 PE=1 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 35/101 (34.65%), Postives = 61/101 (60.40%), Query Frame = 1

Query:  301 REVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            RE++LL  L +PN+++ +          ++ E+LS+  L+ Y+       LPL  + +    + +G+ + HS  VIHRDLKP+N+LI++   +K+ADFG+A
Sbjct:   50 REISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQ-DLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLA 149          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: CDC2_RANDY (Cell division control protein 2 homolog OS=Rana dybowskii GN=CDC2 PE=2 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 47/149 (31.54%), Postives = 82/149 (55.03%), Query Frame = 1

Query:  166 RFAHGAHSRLYHGIYK--DEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIAL-DIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            +   G +  +Y G++K   + VA+K IR+ +++E     A       RE++LL  L +PN++  +    +     +I E+LS   L+ YL  +         L+   L  I +G+ + H++ V+HRDLKP+N+LID +  +K+ADFG+A
Sbjct:    9 KIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAI------REISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIPSGQYLEAMLVKSYLYQILQGIIFCHARRVLHRDLKPQNLLIDSKGVIKLADFGLA 150          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: CDC2_BOVIN (Cell division control protein 2 homolog OS=Bos taurus GN=CDC2 PE=2 SV=2)

HSP 1 Score: 71.633 bits (174), Expect = 3.462e-12
Identity = 48/149 (32.21%), Postives = 79/149 (53.02%), Query Frame = 1

Query:  166 RFAHGAHSRLYHGIYKD--EPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIAL-DIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            +   G +  +Y G +K   + VA+K IR+  ++E     A       RE++LL  L +PN++       +     +I E+LS   L+ YL  +         L+   L  I +G+ + HS+ V+HRDLKP+N+LID +  +K+ADFG+A
Sbjct:    9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAI------REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA 150          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: Y9863_DICDI (Probable serine/threonine-protein kinase DDB_G0281745 OS=Dictyostelium discoideum GN=DDB_G0281745 PE=3 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 4.522e-12
Identity = 46/165 (27.88%), Postives = 87/165 (52.73%), Query Frame = 1

Query:  124 DEHTVDLSQL-FLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACK--KPPVYCVITEYLSEGSLRAYLHKLEHKTLPLP--KLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            D   +D  +L F+G     G +  +  G +   PVA+K +   +++E E L         RE+ +L  + +P +++F+   +  K  ++ +ITE++  G L      L    +PL   + + I+LDIA+   ++H++G++HRDLK +N+L+      K+ D G+A
Sbjct:  324 DMWNIDYKELKFVGNEIGSGKYGSVSLGYWLGTPVAIKKLH-ENNEETEILV-------QRELQILKEIRHPQIVQFLGVSRNEKDEIH-IITEFMDGGDL---FDALIFGDIPLTWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLSTNRRAKLCDLGLA 476          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: Y8901_DICDI (Probable serine/threonine-protein kinase DDB_G0278901 OS=Dictyostelium discoideum GN=DDB_G0278901 PE=3 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 4.522e-12
Identity = 42/144 (29.17%), Postives = 74/144 (51.39%), Query Frame = 1

Query:  178 GAHSRLYHGIYKDEPV--AVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            G    +Y G++K +    A+K I+I    + + L +  +     E+ LL  L + N++++           ++ E++  GSL   + +  H  LP   +      +  G+EY+H QGVIHRD+K  N+LI  +  +K+ADFG+A
Sbjct:   31 GGFGVVYKGLHKTKGYFSAIKKIKIM---KKKKLQSESQISLMAEINLLKVLSHHNIVRYYEHIPSSSHSYIVMEFIENGSLEKIIKR--HGLLPESLVTVYIAQVLNGLEYLHRQGVIHRDIKAANLLISTDGSIKLADFGVA 169