CB250328

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: Y9866_DICDI (Probable serine/threonine-protein kinase DDB_G0271402 OS=Dictyostelium discoideum GN=DDB_G0271402 PE=3 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 5.162e-16
Identity = 54/196 (27.55%), Postives = 88/196 (44.90%), Query Frame = 1

Query:  115 DAADEHTVDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLP---------------------------------LPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            D ++   +++  L  G     GA+ +++ G Y   PVA+K I +     N+     L K   REVA+L R  +PN+++F+   ++     ++TE++  G L  YL + +    P                                  P  I IA D+A  M Y+HS+ VIHRDLK  N+L+   + +K+ D G A
Sbjct:   23 DGSNAFKINIDDLEFGQEIGKGAYGKIFKGEYFGTPVAIKEISL---QPNDVKYKDLTKFIQREVAML-RFSHPNLVQFIGVSERGSSLYIVTEFVQGGDLAYYLFRNKFDDTPEQYIHRKVNVGSSSTPDLSDPTVHNGEKLVQLAWPLRIKIAYDVACAMAYLHSRNVIHRDLKSTNLLVGDNWRIKVCDMGFA 214          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: RAF1_RAT (RAF proto-oncogene serine/threonine-protein kinase OS=Rattus norvegicus GN=Raf1 PE=1 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 5.162e-16
Identity = 49/156 (31.41%), Postives = 87/156 (55.77%), Query Frame = 1

Query:  136 VDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            ++ S++ L  R   G+   +Y G +  + VAVKI+++ D    +  A      F  EVA+L +  + N++ F+    K  +  ++T++    SL  +LH  E K   + +LI IA   A+GM+Y+H++ +IHRD+K  N+ + +   +KI DFG+A
Sbjct:  344 IEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQLQA------FRNEVAVLRKTRHVNILLFMGYMTKDNL-AIVTQWCEGSSLYKHLHVQETK-FQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA 490          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: RAF1_MOUSE (RAF proto-oncogene serine/threonine-protein kinase OS=Mus musculus GN=Raf1 PE=1 SV=2)

HSP 1 Score: 84.3445 bits (207), Expect = 5.162e-16
Identity = 49/156 (31.41%), Postives = 87/156 (55.77%), Query Frame = 1

Query:  136 VDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            ++ S++ L  R   G+   +Y G +  + VAVKI+++ D    +  A      F  EVA+L +  + N++ F+    K  +  ++T++    SL  +LH  E K   + +LI IA   A+GM+Y+H++ +IHRD+K  N+ + +   +KI DFG+A
Sbjct:  344 IEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQLQA------FRNEVAVLRKTRHVNILLFMGYMTKDNL-AIVTQWCEGSSLYKHLHVQETK-FQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA 490          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: PYK4_DICDI (Dual specificity protein kinase pyk4 OS=Dictyostelium discoideum GN=pyk4 PE=1 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 5.162e-16
Identity = 58/169 (34.32%), Postives = 91/169 (53.85%), Query Frame = 1

Query:  178 GAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAAC----KKPPVYCVITEYLSEGSLRAYLHKLEHKTLPL-PKL-IAIALDIARGMEYIHSQGVIHRDLKPENVLI---------------DQEFH------LKIADFGIA 603
            G  S +  G Y +  VA+K+I+     EN T+       F  EV ++S L +PN+++F+AAC     K   +C+++E++S G+L  ++   E K L + P L + I LDIA+GM Y H QG+IHRDL   NVL+               D++F+       K+ DFG++
Sbjct:  308 GFFSVVKKGYYNETEVAIKLIK-KAHGENVTVC----DTFYHEVLIISNLRHPNIVQFIAACIKFDNKEVNHCIVSEWMSGGNLSQFISN-ERKILEINPHLRVKILLDIAKGMLYSHRQGIIHRDLTSNNVLLNFRKKKLLNNNSSNNDEQFYDSDEIIAKVCDFGLS 470          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: FER_CANFA (Proto-oncogene tyrosine-protein kinase Fer OS=Canis familiaris GN=FER PE=2 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 5.162e-16
Identity = 54/173 (31.21%), Postives = 92/173 (53.18%), Query Frame = 1

Query:   91 GGVRVNAVDAADEHTVDLSQLFLGLRFAHGAHSRLYHGIYKDEP-VAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAAC-KKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            G V +N +    +  ++   + LG     G    +Y GI KD+  VAVK  +       E L   L+ +F +E  +L +  +PN++K +  C ++ P+Y +I E +  G   ++L K + + + L +L+  +LD A GM Y+ S+  IHRDL   N L+ +   LKI+DFG++
Sbjct:  543 GVVLLNPIPKDKKWVLNHEDVTLGELLGKGNFGEVYKGILKDKTAVAVKTCK-------EDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPIY-IIMELVPGGDFLSFLRKKKDE-IKLKQLVKFSLDAASGMSYLESKNCIHRDLAARNCLVGENNVLKISDFGMS 706          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: ABL_FSVHY (Tyrosine-protein kinase transforming protein Abl OS=Feline sarcoma virus (strain Hardy-Zuckerman 2) GN=ABL PE=2 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 5.162e-16
Identity = 39/160 (24.38%), Postives = 86/160 (53.75%), Query Frame = 1

Query:  124 DEHTVDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            D+  ++ + + +  +   G +  +Y G++K   + V +  + +D           ++F +E A++  + +PN+++ +  C + P + +ITE+++ G+L  YL +   + +    L+ +A  I+  MEY+  +  IHRDL   N L+ +   +K+ADFG++
Sbjct:  182 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEV-------EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 334          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: ABL1_HUMAN (Proto-oncogene tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4)

HSP 1 Score: 84.3445 bits (207), Expect = 5.162e-16
Identity = 39/160 (24.38%), Postives = 86/160 (53.75%), Query Frame = 1

Query:  124 DEHTVDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            D+  ++ + + +  +   G +  +Y G++K   + V +  + +D           ++F +E A++  + +PN+++ +  C + P + +ITE+++ G+L  YL +   + +    L+ +A  I+  MEY+  +  IHRDL   N L+ +   +K+ADFG++
Sbjct:  233 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEV-------EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 385          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: YES_AVISY (Tyrosine-protein kinase transforming protein Yes (Fragment) OS=Avian sarcoma virus (strain Y73) GN=V-YES PE=3 SV=2)

HSP 1 Score: 83.9593 bits (206), Expect = 6.742e-16
Identity = 49/163 (30.06%), Postives = 84/163 (51.53%), Query Frame = 1

Query:  118 AADEHTVDLSQLFLGLRFAHGAHSRLYHGIYKDEP-VAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            A D   +    L L ++   G    ++ G +     VA+K ++         L   + + F +E  ++ +L +  ++   A   + P+Y ++TE++++GSL  +L + E K L LP+L+ +A  IA GM YI     IHRDL+  N+L+      KIADFG+A
Sbjct:  256 AKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLK---------LGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIY-IVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLA 408          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: RIPK1_HUMAN (Receptor-interacting serine/threonine-protein kinase 1 OS=Homo sapiens GN=RIPK1 PE=1 SV=3)

HSP 1 Score: 83.9593 bits (206), Expect = 6.742e-16
Identity = 43/100 (43.00%), Postives = 64/100 (64.00%), Query Frame = 1

Query:  304 EVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            E  +++RL +  V+K +    +   Y ++ EY+ +G+L   L K E  T PL     I L+I  GM Y+H +GVIH+DLKPEN+L+D +FH+KIAD G+A
Sbjct:   63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVL-KAEMST-PLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLA 160          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: RAF1_PONAB (RAF proto-oncogene serine/threonine-protein kinase OS=Pongo abelii GN=RAF1 PE=2 SV=1)

HSP 1 Score: 83.9593 bits (206), Expect = 6.742e-16
Identity = 49/156 (31.41%), Postives = 87/156 (55.77%), Query Frame = 1

Query:  136 VDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            ++ S++ L  R   G+   +Y G +  + VAVKI+++ D    +  A      F  EVA+L +  + N++ F+    K  +  ++T++    SL  +LH  E K   + +LI IA   A+GM+Y+H++ +IHRD+K  N+ + +   +KI DFG+A
Sbjct:  344 IEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQA------FRNEVAVLRKTRHVNILLFMGYMTKDNL-AIVTQWCEGSSLYKHLHVQETK-FQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA 490