CB250328

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: M3K11_RAT (Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus GN=Map3k11 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 8.805e-16
Identity = 57/155 (36.77%), Postives = 81/155 (52.26%), Query Frame = 1

Query:  178 GAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQG---VIHRDLKPENVLIDQEFH--------LKIADFGIACE 609
            G   ++Y G ++ E VAVK  R  D DE+ ++ A   +Q   E  L + L +PN+I   A C + P  C++ EY + G L      L  + +P   L+  A+ IARGM Y+H +    VIHRDLK  N+L+ Q           LKI DFG+A E
Sbjct:  127 GGFGKVYRGSWRGELVAVKAAR-QDPDEDISVTAESVRQ---EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLS---RALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLARE 274          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: M3K11_MOUSE (Mitogen-activated protein kinase kinase kinase 11 OS=Mus musculus GN=Map3k11 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 8.805e-16
Identity = 57/155 (36.77%), Postives = 81/155 (52.26%), Query Frame = 1

Query:  178 GAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQG---VIHRDLKPENVLIDQEFH--------LKIADFGIACE 609
            G   ++Y G ++ E VAVK  R  D DE+ ++ A   +Q   E  L + L +PN+I   A C + P  C++ EY + G L      L  + +P   L+  A+ IARGM Y+H +    VIHRDLK  N+L+ Q           LKI DFG+A E
Sbjct:  127 GGFGKVYRGSWRGELVAVKAAR-QDPDEDISVTAESVRQ---EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLS---RALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLARE 274          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: M3K11_HUMAN (Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 8.805e-16
Identity = 57/155 (36.77%), Postives = 81/155 (52.26%), Query Frame = 1

Query:  178 GAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQG---VIHRDLKPENVLIDQEFH--------LKIADFGIACE 609
            G   ++Y G ++ E VAVK  R  D DE+ ++ A   +Q   E  L + L +PN+I   A C + P  C++ EY + G L      L  + +P   L+  A+ IARGM Y+H +    VIHRDLK  N+L+ Q           LKI DFG+A E
Sbjct:  126 GGFGKVYRGSWRGELVAVKAAR-QDPDEDISVTAESVRQ---EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLS---RALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLARE 273          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: SRK3_SPOLA (Tyrosine-protein kinase SRK3 (Fragment) OS=Spongilla lacustris GN=SRK3 PE=2 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.150e-15
Identity = 50/162 (30.86%), Postives = 87/162 (53.70%), Query Frame = 1

Query:  124 DEHTVDLSQLFLGLRFAHGAHSRLYHGIYKDEP-VAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACK-KPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            DE  +D + + L  +   G    ++ G++     VAVK ++ PD  E         K F +E  ++ ++H+PN+++  A C    P+Y ++TE +  GS+  YL   E K + L +++ ++  IA GM Y+ +   IHRDL   N+L+ +    K+ADFG+A
Sbjct:   57 DEWEIDRTTIQLQRKLGQGNFGEVWAGVWNGTTAVAVKTLK-PDTME--------VKDFVQEAQVMKKIHHPNLLQLYAVCTIGEPIY-IVTELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAARNILVGEGNVCKVADFGLA 208          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: M3K9_MOUSE (Mitogen-activated protein kinase kinase kinase 9 OS=Mus musculus GN=Map3k9 PE=2 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.150e-15
Identity = 56/170 (32.94%), Postives = 85/170 (50.00%), Query Frame = 1

Query:  136 VDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRI-PDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQG---VIHRDLKPENVLIDQEFH--------LKIADFGIACE 609
            +D ++L L      G   ++Y   +  + VAVK  R  PD+D ++T+     +   +E  L + L +PN+I     C K P  C++ E+   G L      L  K +P   L+  A+ IARGM Y+H +    +IHRDLK  N+LI Q+          L+I DFG+A E
Sbjct:  132 IDFAELTLEEIIGIGGFGKVYRAFWAGDEVAVKAARHDPDEDISQTI-----ENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLN---RVLSGKRIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILEITDFGLARE 293          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: M3K10_MOUSE (Mitogen-activated protein kinase kinase kinase 10 OS=Mus musculus GN=Map3k10 PE=2 SV=2)

HSP 1 Score: 83.1889 bits (204), Expect = 1.150e-15
Identity = 53/155 (34.19%), Postives = 80/155 (51.61%), Query Frame = 1

Query:  178 GAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQG---VIHRDLKPENVLIDQEFH--------LKIADFGIACE 609
            G   ++Y  +++ E VAVK  R+ D + +  + A   +Q  +E  L   L +PN+I    AC  PP  C++ EY   G+L      L  + +P   L+  A+ +ARGM Y+H+     +IHRDLK  N+LI +           LKI DFG+A E
Sbjct:  107 GGFGKVYRAVWRGEEVAVKAARL-DPERDPAVTA---EQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALS---RVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLARE 254          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: DLK1_CAEEL (Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis elegans GN=dlk-1 PE=1 SV=4)

HSP 1 Score: 83.1889 bits (204), Expect = 1.150e-15
Identity = 45/114 (39.47%), Postives = 60/114 (52.63%), Query Frame = 1

Query:  259 ENETLAARLEKQFNR-EVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFG 597
            EN T+A +   Q    E+  L  L + N+I+F+  C K P YC++ EY S+G L   L      T+          +IA GM Y+H   VIHRDLK  N+LI  E  +KI DFG
Sbjct:  155 ENRTVAVKKVNQLKETEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVLKS--RNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFG 266          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: Y1839_ARATH (Probable serine/threonine-protein kinase At1g18390 OS=Arabidopsis thaliana GN=At1g18390 PE=1 SV=2)

HSP 1 Score: 82.8037 bits (203), Expect = 1.502e-15
Identity = 49/146 (33.56%), Postives = 86/146 (58.90%), Query Frame = 1

Query:  178 GAHSRLYHGIYKD-EPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIK-FVAACKKPPVYCVITEYLSEGSLRAYLH--KLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIA 603
            G    +Y+G  KD   VAVK  R+ D++          +QF  EV +L+ L +PN++  F  + K+     ++ EY++ G+L  +LH  +    +LP    + IA++ A  ++Y+H+  +IHRD+K  N+L+DQ F++K+ADFG++
Sbjct:  353 GGFGTVYYGKLKDGRSVAVK--RLYDNNFKRA------EQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVANGTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLHASKIIHRDVKSNNILLDQNFNVKVADFGLS 490          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: PATS1_DICDI (Probable serine/threonine-protein kinase pats1 OS=Dictyostelium discoideum GN=pats1 PE=3 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.502e-15
Identity = 51/168 (30.36%), Postives = 92/168 (54.76%), Query Frame = 1

Query:  136 VDLSQLFLGLRFAHGAHSRLYHGIYKDEPVAVKIIRIPDD-----DENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQ--GVIHRDLKPENVLI-----DQEFHLKIADFGIA 603
            +   QL +      G  + +Y   ++ + VAVK ++  ++     + N+   ++   +F RE  ++S L +PN+++    C  P   C++TEYL  G+L ++LHK E +   L +L  +ALDI+ GM ++HS    +IHRDLK  N+L+     + +   K+ DFG++
Sbjct: 2242 IPFDQLMIEELIGEGGAALVYRARWQGQTVAVKKLKTIENLDSPIEINDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCLDP--LCIVTEYLPHGNLYSFLHKPEMEFSWLFRL-KVALDISSGMAFLHSSTPPIIHRDLKSPNILLASINENAQTIAKVVDFGLS 2406          

BLAST of CB250328 vs. ExPASy Swiss-Prot
Match: M3K13_PONAB (Mitogen-activated protein kinase kinase kinase 13 OS=Pongo abelii GN=MAP3K13 PE=2 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.502e-15
Identity = 51/144 (35.42%), Postives = 75/144 (52.08%), Query Frame = 1

Query:  178 GAHSRLYHGIYKDEPVAVKIIRIPDDDENETLAARLEKQFNREVALLSRLHNPNVIKFVAACKKPPVYCVITEYLSEGSLRAYLHKLEHKTLPLPKLIAIALDIARGMEYIHSQGVIHRDLKPENVLIDQEFHLKIADFGIACE 609
            GA   ++ G ++ E VA+K +R    ++NET           ++  L +L +PN+I F   C + P YC+I EY + G L   L      T  L  L+  +  IA GM Y+H   +IHRDLK  NVL+     +KI+DFG + E
Sbjct:  177 GAQGAVFLGKFRAEEVAIKKVR----EQNET-----------DIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRL--LVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKE 303