CB290363

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: ERYA3_SACER (Erythronolide synthase, modules 5 and 6 OS=Saccharopolyspora erythraea GN=eryA PE=1 SV=4)

HSP 1 Score: 100.138 bits (248), Expect = 1.337e-20
Identity = 63/180 (35.00%), Postives = 89/180 (49.44%), Query Frame = 2

Query:  215 TNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            +++ S  +A  LG  GP  ++ TAC++     + A   +RR E  L LAGG      P   G F   R  SQ         +P+ K  DGF + EGAGVLV++ L  A + G P++A   G AVN D          G      I  +LE+AGV   +V+Y+ AH T T  GD  E++A+
Sbjct:  175 SSVASGRVAYCLGLEGPAMTVDTACSSGLTALHLAMESLRRDECGLALAGGVTVMSSP---GAFTEFR--SQGGLAADGRCKPFSKAADGFGLAEGAGVLVLQRLSAARREGRPVLAVLAGSAVNQDGASNGLTAPSGPAQQRVIRRALENAGVRAGDVDYVEAHGTGTRLGDPIEVHAL 349          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: ERYA1_SACER (Erythronolide synthase, modules 1 and 2 OS=Saccharopolyspora erythraea GN=eryA PE=1 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.280e-20
Identity = 59/197 (29.95%), Postives = 96/197 (48.73%), Query Frame = 2

Query:  164 IEKGHRKITPFFIPYAITNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            + +G   +  + +    T++ S  +A  LG  GP  S+ TAC++S    + A   +RRGE+ L +AGG      P  L  F    +L+     P    + +    +GF M EGAG+L++E L  A + G P++A   G AVN D         +G      I+ +L ++G+ P +++ + AH T T  GD  E  A+
Sbjct:  636 LAEGGEGVEGYLMTGTTTSVASGRIAYTLGLEGPAISVDTACSSSLVAVHLACQSLRRGESSLAMAGGVTVMPTPGMLVDFSRMNSLA-----PDGRCKAFSAGANGFGMAEGAGMLLLERLSDARRNGHPVLAVLRGTAVNSDGASNGLSAPNGRAQVRVIQQALAESGLGPADIDAVEAHGTGTRLGDPIEARAL 827          

HSP 2 Score: 83.1889 bits (204), Expect = 1.691e-15
Identity = 52/179 (29.05%), Postives = 82/179 (45.81%), Query Frame = 2

Query:  218 NMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            ++ S  +A  LG  GP  ++ TAC++S    + A   +R G+  L +AGG      P     F    ALS     P    +P+  + DGF +GEG+  +V++ L  A + G  ++    G AVN D          G+     I  +   AG++  +V  + AH T T  GD  E +A+
Sbjct: 2125 SVASGRIAYVLGLEGPALTVDTACSSSLVALHTACGSLRDGDCGLAVAGGVSVMAGPEVFTEFSRQGALS-----PDGRCKPFSDEADGFGLGEGSAFVVLQRLSDARREGRRVLGVVAGSAVNQDGASNGLSAPSGVAQQRVIRRAWARAGITGADVAVVEAHGTGTRLGDPVEASAL 2298          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PPSB_MYCTU (Phenolpthiocerol synthesis polyketide synthase ppsB OS=Mycobacterium tuberculosis GN=ppsB PE=3 SV=2)

HSP 1 Score: 94.7449 bits (234), Expect = 5.617e-19
Identity = 59/169 (34.91%), Postives = 81/169 (47.93%), Query Frame = 2

Query:  248 LGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            LG  GP  ++ TAC++S    + A   +R  E DL LAGG    + P       A   LS     PQ     +D   DGFV GEGAGV+V++ L  A++ G  ++A   G AVN D         +       I  +L    V+P+ VNY+ AH T T+ GD  E  A+
Sbjct:  192 LGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRPETQIAISAWGLLS-----PQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEAL 355          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PPSA_MYCTU (Phenolpthiocerol synthesis polyketide synthase ppsA OS=Mycobacterium tuberculosis GN=ppsA PE=3 SV=2)

HSP 1 Score: 94.7449 bits (234), Expect = 5.617e-19
Identity = 60/186 (32.26%), Postives = 90/186 (48.39%), Query Frame = 2

Query:  215 TNMGSAL------LAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            +N G A+      L+  L   GP+ ++ TAC++S    + A   +R  +  L +A G    + P    GF    ALS     P    R +D   DGFV GEGAGV+V++ L  A + G  ++A   G AVN D         +     + + ++  +AG+ P EV+Y+ AH T TL GD  E  A+
Sbjct:  243 SNSGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALS-----PTGQCRAFDATADGFVRGEGAGVVVLKRLTDAQRDGDRVLAVICGSAVNQDGRSNGLMAPNPAAQMAVLRAAYTNAGMQPSEVDYVEAHGTGTLLGDPIEARAL 423          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKSF_BACSU (Polyketide biosynthesis malonyl-ACP decarboxylase pksF OS=Bacillus subtilis GN=pksF PE=1 SV=3)

HSP 1 Score: 94.3597 bits (233), Expect = 7.335e-19
Identity = 62/191 (32.46%), Postives = 93/191 (48.69%), Query Frame = 2

Query:  206 YAITNMGSALLAI---DLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRN-----DDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            Y ++ M S L  I     G  G  Y++  A A+       A   +  GE D  +A G   A++ +      A RAL         D+P+ A RP+D++RDGF+ GE  G LV+E  E A++RG    A   G ++  D     DP  +  G    I+ +LE A + PE+++YIN H T +  GD  E+ A+
Sbjct:  134 YGLSFMDSDLCGICTDQFGITGLAYTVGGASASGQLAVIHAIQQVLSGEVDTCIALG---ALMDLSYMECEALRALGAMGTDKYADEPENACRPFDQNRDGFIYGESCGALVIERKETALRRGLKPYAALSGWSIKLDGNRNPDPSLE--GEIHVIQKALERARLLPEDIDYINPHGTGSFIGDEIELKAL 319          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: OL56_STRAT (Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces antibioticus GN=orfB PE=3 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 4.755e-18
Identity = 60/182 (32.97%), Postives = 86/182 (47.25%), Query Frame = 2

Query:  215 TNMGSAL--LAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            T +G+A   +A   G  GP  ++ TAC++S    + A   +RRGE  L L GG      P+ L  F   R LS          + +    DGF   EG GVL++E L  A + G  ++A   G AVN D         +G      I ++L DAG++P +V+ + AH T T  GD  E  A+
Sbjct:  184 TTLGAASGRVAYTFGLEGPAVTVDTACSSSLVALHLAVQGLRRGECSLALVGGVTVMSSPVTLTTFSRQRGLSVDG-----RCKAFPASADGFGAAEGVGVLLVERLSDARRLGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADAGLAPADVDVVEAHGTGTRLGDPIEAQAL 360          

HSP 2 Score: 83.9593 bits (206), Expect = 9.914e-16
Identity = 56/187 (29.95%), Postives = 86/187 (45.99%), Query Frame = 2

Query:  206 YAITNMGSALLA----IDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            Y +T   SA+L+       G  GP  ++ TAC++S    + A   +RRGE  L +AGG      P     F   + +++       A+       DG   GEG  +L++E L  A + G  ++A   G AVN D         +G      I ++L DAG++P +V+ + AH T T  GD  E  A+
Sbjct: 1828 YLLTGTASAVLSGRISYTFGLEGPAVTVDTACSSSLVALHLAVQALRRGECSLAIAGGVAVMSTPDAFVEFSRQQGMARDGRCKAFAAAA-----DGMGWGEGVSLLLLERLSDARRLGHRVLAVVRGSAVNQDGASNGLAAPNGPSQQRVIRAALADAGLAPADVDVVEAHGTGTRLGDPIEAQAL 2009          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKSN_BACSU (Polyketide synthase pksN OS=Bacillus subtilis GN=pksN PE=1 SV=3)

HSP 1 Score: 91.2781 bits (225), Expect = 6.210e-18
Identity = 59/202 (29.21%), Postives = 93/202 (46.04%), Query Frame = 2

Query:  149 GVQALIEKGHRKITPFFIPYAITNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            G  +L+ K +  I          ++G   ++  L   GP+  + TAC++S    + A + I  G  D+ LAGG    I+P     F    ALS+     +   + +    DGF  GEGAG+L ++ L+ A + G  I     G A+N      +    +    +  I+S+ + AG+ P+ V YI AH T T  GD  EIN +
Sbjct: 2701 GYSSLLSKANSAIEGSAAANTSPSVGPNRVSYFLNLHGPSEPVDTACSSSLVAIHHAISSIEEGTCDMALAGGVNTIILPEVYISFDKAGALSK-----EGKCKTFSNQADGFAHGEGAGILFLKKLKAAEEAGDHIYGVIKGSAINHGGRAASLTTPNPKAQADVIQSAYQKAGIDPKTVTYIEAHGTGTELGDPVEINGL 2897          

HSP 2 Score: 82.8037 bits (203), Expect = 2.209e-15
Identity = 53/173 (30.64%), Postives = 81/173 (46.82%), Query Frame = 2

Query:  248 LGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVN----CDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            L   GP+  I TAC++S    + A   I  G  ++ +AGG    + P G   +    ALS+         + +    DGF + EGAG+L ++ L  A + G  I     G AVN     ++    +P+A     +  ++++ E AG+ P  V YI AH T T  GD  EIN +
Sbjct: 4232 LNIHGPSEPIDTACSSSLVAIHHAVCAIENGNCEMAIAGGVNTVVTPQGHIAYDKAGALSKEG-----RCKTFSDKADGFAVSEGAGILFLKKLTAAERDGDHIYGVIKGSAVNHGGRANSLTTPNPKAQ----ADVVKTAYEKAGIDPRTVTYIEAHGTGTELGDPVEINGL 4395          

HSP 3 Score: 72.7886 bits (177), Expect = 2.286e-12
Identity = 53/189 (28.04%), Postives = 88/189 (46.56%), Query Frame = 2

Query:  197 FIPYAITNMGS--ALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGL-GVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            ++ + +   G+   +++  LG  GP+Y + + C++S    Y A   +  GE+   L GG  A +      G+V    L+  +D    A   +D   DG   GEG  V++++    A+K G  I A   G  +N D        A  + G +  I+  L+   + PE V+YI AH T T  GD  E++A+
Sbjct: 1229 YVSWVLAQSGTIPTMISHKLGLKGPSYFVHSNCSSSLVGLYQAYKSLTSGESQYALVGG--ATLHAQSAIGYVHQNGLNFSSDGHVKA---FDASADGMAGGEGVAVILLKKAVDAVKDGDHIYAIMRGIGINNDGAEKAGFYAPSVKGQTEVIQHVLDTTKIHPETVSYIEAHGTGTKLGDPIEMSAL 1412          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: MYCA_BACSU (Mycosubtilin synthase subunit A OS=Bacillus subtilis GN=mycA PE=3 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 2.360e-17
Identity = 54/186 (29.03%), Postives = 92/186 (49.46%), Query Frame = 2

Query:  206 YAITNMGSAL---LAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            Y + N+ S L   +A  L   GP  ++ TAC++S    + A   +  G+ ++ LAGG   +++P+ +G       L   + D  T  + + KD DG   GEG   ++++ L+ A++ G  I     G A+N D   +          +  IE + +DAG++PE +++I AH T T  GD  E N +
Sbjct:  813 YIVGNLPSVLASRIAYFLNLKGPAVTVDTACSSSLVAVHMACKALLTGDCEMALAGGIRTSLLPMRIG-------LDMESSDGLT--KTFSKDSDGTGSGEGVAAVLLKPLQAAIRDGDHIYGVIKGSAINQDGTTVGITAPSPAAQTEVIEMAWKDAGIAPETLSFIEAHGTGTKLGDPVEFNGL 989          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKS16_DICDI (Probable polyketide synthase 16 OS=Dictyostelium discoideum GN=pks16 PE=2 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 4.025e-17
Identity = 57/192 (29.69%), Postives = 88/192 (45.83%), Query Frame = 2

Query:  203 PYAITNMGSALLAIDLGFM----GPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYH----MTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            PY +T    + ++  L F     GP+ ++ TAC++S    Y     I  G++ + + GG      P     F     L  +        R +D   DG++  EG GV +++    A+K G  I     GG+ N D Y+    +T P     G +  IE +L+ +GV+P ++ YI AH T T  GD  EI AI
Sbjct:  147 PYTVTGSAGSFVSNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIATGDSKMAIVGGVNGIFDPSISMTFSGLNMLGHKGQ-----CRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNITQPSMKAQGEN--IEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAI 331          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKS17_DICDI (Probable polyketide synthase 17 OS=Dictyostelium discoideum GN=pks17 PE=3 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 8.967e-17
Identity = 55/194 (28.35%), Postives = 86/194 (44.33%), Query Frame = 2

Query:  185 ITPFFIPYAITNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYH----MTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            + P+  P    +  S  L+      GP+ ++ TAC++S    Y     I  G++ + + GG      P     F     L  +        R +D   DG++  EG GV +++    A+K G  I     GG+ N D Y+    +  P     G +  IE +L+ +GV+P ++ YI AH T T  GD  EI AI
Sbjct:  145 VNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQ-----CRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGEN--IEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAI 331