CB290363

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKSR_BACSU (Polyketide synthase pksR OS=Bacillus subtilis GN=pksR PE=1 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 1.750e-12
Identity = 50/190 (26.32%), Postives = 88/190 (46.32%), Query Frame = 2

Query:  185 ITPFFIPYAITNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            + P  IP  I+       A+D+   GP+     AC+++    + A   IR GE +  + G     + P G  GF +   LS++       ++ +  D +GFV  EGAGVL+++ L+ A++    I +   G  V+     M+    +  G+   +  + + A + P+ V YI AH  ++   D  EI A+
Sbjct: 1654 VVPSLIPNRIS------YALDV--KGPSEYYEAACSSALVALHRAIQSIRNGECEQAIVGAVNLLLSPKGFIGFDSMGYLSEKGQ-----AKSFQADANGFVRSEGAGVLIIKPLQKAIEDSDHIYSVIKGSGVSHGGRGMSLHAPNPAGMKDAMLKAYQGAQIDPKTVTYIEAHGIASPLADAIEIEAL 1830          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: KAS2_STRCN (Putative polyketide beta-ketoacyl synthase 2 OS=Streptomyces cyaneus GN=curB PE=3 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.750e-12
Identity = 58/201 (28.86%), Postives = 93/201 (46.27%), Query Frame = 2

Query:  152 VQALIEKGHRKITPFFIPYAITNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            +Q L  +G R + P+          +  ++I  GF GP   +++  A        AA  + RG  D+++ G  EA + P  +   +    LS  ++DP  A RP+     GFV  EG  VL++E  + A +RGA + A   G A         D   +GL  +  I  +L++AG +PEE++ + A A      D AE  A+
Sbjct:  129 LQKLWGQGSRFVGPYQSIAWFYAASTGQISIRSGFKGPCGVVASDEAGGLDAVAHAARVVERG-TDVVVVGAAEAPLAPYSMVCQLGYPELST-DEDPAIAYRPFTSAARGFVPAEGGAVLIVEEADRAHRRGAVVRATVAGHAATFTGASHWDQSREGL--AHAIHGALDEAGCAPEEIDVVFADAMGVPEADRAEALAL 325          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PHAS_MYCTU (Phthioceranic/hydroxyphthioceranic acid synthase OS=Mycobacterium tuberculosis GN=pks2 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.899e-12
Identity = 50/179 (27.93%), Postives = 77/179 (43.02%), Query Frame = 2

Query:  218 NMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            +M S  +A  +   GP  ++ TAC++     + A   +  GE+D+ LAGG    + P       A   LS     P    R +D   DGFV GEG  V+V++ L  A+  G  I+A   G + N D + +           +   ++L   GV    V  + AH   T  GD  E  ++
Sbjct:  173 SMASGRVAYAMRLHGPAITVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLS-----PTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYASV 346          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PHAS_MYCTA (Phthioceranic/hydroxyphthioceranic acid synthase OS=Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) GN=pks2 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.899e-12
Identity = 50/179 (27.93%), Postives = 77/179 (43.02%), Query Frame = 2

Query:  218 NMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            +M S  +A  +   GP  ++ TAC++     + A   +  GE+D+ LAGG    + P       A   LS     P    R +D   DGFV GEG  V+V++ L  A+  G  I+A   G + N D + +           +   ++L   GV    V  + AH   T  GD  E  ++
Sbjct:  173 SMASGRVAYAMRLHGPAITVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLS-----PTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYASV 346          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PHAS_MYCBP (Phthioceranic/hydroxyphthioceranic acid synthase OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) GN=pks2 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.899e-12
Identity = 50/179 (27.93%), Postives = 77/179 (43.02%), Query Frame = 2

Query:  218 NMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            +M S  +A  +   GP  ++ TAC++     + A   +  GE+D+ LAGG    + P       A   LS     P    R +D   DGFV GEG  V+V++ L  A+  G  I+A   G + N D + +           +   ++L   GV    V  + AH   T  GD  E  ++
Sbjct:  173 SMASGRVAYAMRLHGPAITVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLS-----PTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYASV 346          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PHAS_MYCBO (Phthioceranic/hydroxyphthioceranic acid synthase OS=Mycobacterium bovis GN=pks2 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.899e-12
Identity = 50/179 (27.93%), Postives = 77/179 (43.02%), Query Frame = 2

Query:  218 NMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            +M S  +A  +   GP  ++ TAC++     + A   +  GE+D+ LAGG    + P       A   LS     P    R +D   DGFV GEG  V+V++ L  A+  G  I+A   G + N D + +           +   ++L   GV    V  + AH   T  GD  E  ++
Sbjct:  173 SMASGRVAYAMRLHGPAITVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLS-----PTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYASV 346          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKSJ_BACSU (Polyketide synthase pksJ OS=Bacillus subtilis GN=pksJ PE=1 SV=3)

HSP 1 Score: 71.633 bits (174), Expect = 5.092e-12
Identity = 49/188 (26.06%), Postives = 83/188 (44.15%), Query Frame = 2

Query:  206 YAITNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGG-----TEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            + I ++G   ++  L   GP+  + TAC++S    + A   ++ G+ ++ +AGG     TE A I     G ++               + +  D +G+V GEG G+++++ LE A + G  I     G A N      T    +    +  +  +   A + P  V YI AH T T  GD  EIN +
Sbjct: 3484 HMIPSVGPNRMSYFLNIHGPSEPVETACSSSLVAIHRAVTAMQNGDCEMAIAGGVNTILTEEAHISYSKAGMLS----------TDGRCKTFSADANGYVRGEGVGMVMLKKLEDAERDGNHIYGVIRGTAENHGGRANTLTSPNPKAQADLLVRAYRQADIDPSTVTYIEAHGTGTELGDPIEINGL 3661          

HSP 2 Score: 70.0922 bits (170), Expect = 1.481e-11
Identity = 53/193 (27.46%), Postives = 89/193 (46.11%), Query Frame = 2

Query:  197 FIPYAITNMGS--ALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGG----TEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGL-GVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            ++ + +   G+   +++  LG  GP+Y +   C++S    ++A   +  GE+D  L GG    TE+ I      G+V    L+  +D    A   +D   DG + GEG  V++++    A+K G  I A   G  VN D        A  + G +  ++  +    V PE + Y+ AH T T  GD  E+ A+
Sbjct: 1900 YVSWVLAQSGTIPTMISHKLGLRGPSYFVHANCSSSLIGLHSAYKSLLSGESDYALVGGATLHTESNI------GYVHQPGLNFSSDGHIKA---FDASADGMIGGEGVAVVLLKKAADAVKDGDHIYALLRGIGVNNDGADKVGFYAPSVKGQADVVQQVMNQTKVQPESICYVEAHGTGTKLGDPIELAAL 2083          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKS7_DICDI (Probable polyketide synthase 7 OS=Dictyostelium discoideum GN=pks7 PE=3 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 1.935e-11
Identity = 50/175 (28.57%), Postives = 81/175 (46.29%), Query Frame = 2

Query:  254 FMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDA--------YHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            F GP+ SI TAC++S        + I  G +D+ + GG    +       +     LS+ +       + +D+  DGF  GE AGV+V+++L+ A+K G  I     G + N D         ++    ++    ++S  +S+ E   V+  E+ YI AH T T  GD  E  AI
Sbjct:  170 FNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGK----CKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVN--EIQYIEAHGTGTKTGDPIETEAI 338          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: PKS37_DICDI (Probable polyketide synthase 37 OS=Dictyostelium discoideum GN=stlB PE=2 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.630e-11
Identity = 53/196 (27.04%), Postives = 87/196 (44.39%), Query Frame = 2

Query:  182 KITPFFIPYAITNMGSALLAIDLGFMGPNYSISTACATSNYCFYAAANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDA---YHMTDPRADGLGVSSCIESSLEDAG--VSPEEVNYINAHATSTLAGDLAEINAI 754
            +I  F  P   ++  S  L+  L   GP+ +++TAC+ S    +     +  GE++L + GG      P+    F     L+Q  D        +D    G+V  EG G+L+++ L  A++    I +  L  A N +      +T PR+  L     I+  L ++    S +++ Y   H T T  GDL EI AI
Sbjct:  163 EINQFTTPGTNSSFLSNRLSYFLDVNGPSMTVNTACSASMVAIHLGLQSLWNGESELSMVGGVNIISSPLQSLDFGKAGLLNQETDG---RCYSFDPRASGYVRSEGGGILLLKPLSAALRDNDEIYSLLLNSANNSNGKTPTGITSPRS--LCQEKLIQQLLRESSDQFSIDDIGYFECHGTGTQMGDLNEITAI 353          

BLAST of CB290363 vs. ExPASy Swiss-Prot
Match: KAS2_STRGA (Tetracenomycin C polyketide putative beta-ketoacyl synthase 2 OS=Streptomyces glaucescens GN=tcmL PE=3 SV=2)

HSP 1 Score: 68.1662 bits (165), Expect = 5.630e-11
Identity = 47/146 (32.19%), Postives = 71/146 (48.63%), Query Frame = 2

Query:  317 AANHIRRGEADLMLAGGTEAAIIPIGLGGFVACRALSQRNDDPQTASRPWDKDRDGFVMGEGAGVLVMESLEHAMKRGAPIIAEYLGGAVNCDAYHMTDPRADGLGVSSCIESSLEDAGVSPEEVNYINAHATSTLAGDLAEINAI 754
            AA  +R+G  +  L GG EA++ P GL   +    LS+  D P  A  P+D    G+V GEG  +LV E  + A +R A  +   + G  +   +          G +  I  +LE+A V+PE+V+ + A A    A D AE  A+
Sbjct:  175 AARLLRKGTLNTALTGGCEASLCPWGLVAQIPSGFLSEATD-PHDAYLPFDARAAGYVPGEGGAMLVAERADSARERDAATVYGRIAG--HASTFDARPGTGRPTGPARAIRLALEEARVAPEDVDVVYADAAGVPALDRAEAEAL 317