CB290743

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP4B1_RAT (Cytochrome P450 4B1 OS=Rattus norvegicus GN=Cyp4b1 PE=1 SV=3)

HSP 1 Score: 84.3445 bits (207), Expect = 8.883e-16
Identity = 57/197 (28.93%), Postives = 93/197 (47.21%), Query Frame = -1

Query:  251 SFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQN-----PFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRVSDPNQAPRFAPGLTATVSGGL 826
            +F+  G DT  SG++ F + ++ + E +   R E   I+  +QD   ++ L ++ YL   + E  RL+PPV    +   +     DG  +  G+ ++ H YA+ R   +W PD   F P R      F P+N     PF +  F AG R C+G+  A+ EMK      + +F   + DP++ P   P L      G+
Sbjct:  311 TFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILG-DQDSFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVW-PDPEVFDPLR------FSPENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSL-DPSKMPIKVPQLILRSKNGI 498          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP46A_HUMAN (Cholesterol 24-hydroxylase OS=Homo sapiens GN=CYP46A1 PE=1 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 8.883e-16
Identity = 53/172 (30.81%), Postives = 91/172 (52.91%), Query Frame = -1

Query:  314 VSFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRV 829
            V+F +AG +T A+ L      LS+  E+ + ++ E D+++   + L  FE L  L YL+  + ES+RL+PP     +  +E+ ++ DG  V   T + +  Y MGRM+  +  D   F P+R+   G   P+  F Y  F  GHR C+G+  A +E+K     ++++   R+
Sbjct:  297 VTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYL-DFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI-DGVRVPGNTPLLFSTYVMGRMDTYF-EDPLTFNPDRF---GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRL 462          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP4F5_RAT (Cytochrome P450 4F5 OS=Rattus norvegicus GN=Cyp4f5 PE=2 SV=1)

HSP 1 Score: 83.9593 bits (206), Expect = 1.160e-15
Identity = 54/193 (27.98%), Postives = 94/193 (48.70%), Query Frame = -1

Query:  251 SFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQ-DLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRVSDPNQAPRFAPGLTATVSGGL 826
            +F+  G DT AS L+   + L++H E +   R E  ++++  + + + ++ L +L +L   + ES+RL PP     +   +D +LPDG  + KG       + +     +W PD   F P R+  +     ++P  +  F AG R C+G+  A+ EMK      + +F  RV   ++ PR  P +     GGL
Sbjct:  326 TFMFGGHDTTASALSWILYNLARHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVW-PDPEVFDPFRF-DSENRQKRSPLSFIPFSAGPRNCIGQTFAMNEMKVVVALTLLRF--RVLPDDKEPRRKPEIILRAEGGL 514          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP4AE_RAT (Cytochrome P450 4A14 OS=Rattus norvegicus GN=Cyp4a14 PE=1 SV=2)

HSP 1 Score: 83.9593 bits (206), Expect = 1.160e-15
Identity = 52/178 (29.21%), Postives = 85/178 (47.75%), Query Frame = -1

Query:  293 SFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRVSDPNQAP 826
            +F+  G DT ASG++  F+ L+ H E +   R E   I+      V+++ L ++ Y    + E++RL+PPV   S+        PDG  + KG   T   Y +      W P+   F P R+  +    P++   Y  F  G R C+GK  A+ E+K A    + +F + + DP + P
Sbjct:  314 TFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTS-VTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYW-PNPKVFDPSRFSPDS---PRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL-LPDPTRIP 485          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP46A_MOUSE (Cholesterol 24-hydroxylase OS=Mus musculus GN=Cyp46a1 PE=2 SV=1)

HSP 1 Score: 83.9593 bits (206), Expect = 1.160e-15
Identity = 52/172 (30.23%), Postives = 91/172 (52.91%), Query Frame = -1

Query:  314 VSFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRV 829
            V+F +AG +T A+ L      LS+  E+ + ++ E D+++   + L  +E L  L YL+  + ES+RL+PP     +  +E+ ++ DG  V   T + +  Y MGRM+  +  D   F P+R+   G   P+  F Y  F  GHR C+G+  A +E+K     ++++   R+
Sbjct:  297 VTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHL-DYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI-DGVRVPGNTPLLFSTYVMGRMDTYF-EDPLTFNPDRF---GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRL 462          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: C4D14_DROME (Probable cytochrome P450 4d14 OS=Drosophila melanogaster GN=Cyp4d14 PE=3 SV=1)

HSP 1 Score: 83.9593 bits (206), Expect = 1.160e-15
Identity = 55/172 (31.98%), Postives = 90/172 (52.33%), Query Frame = -1

Query:  320 SFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDL-VSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWL--RNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNI 826
            +F+  G DT  S +    +LL++H EV++ +  E   ++  ++   V+ + L EL YL   + ES+RLFP V    ++  +D +L DG  +   + V    Y   R +  + PD  +F P+R+   R G     +PF Y  F AG R C+G+  A++EMKS    +VR F +
Sbjct:  311 TFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVL-DGKLIPADSNVIILIYHAQR-DPDYFPDPEKFIPDRFSMERKGEI---SPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFEL 477          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP4A6_RABIT (Cytochrome P450 4A6 OS=Oryctolagus cuniculus GN=CYP4A6 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.515e-15
Identity = 55/202 (27.23%), Postives = 95/202 (47.03%), Query Frame = -1

Query:  233 SFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIW-GPDCSE---FKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRVSDPNQAPRFAPGLTATVSGGLPVMVQE 826
            +F+  G DT ASG++  F+ L+ H E +   R E   ++      +++E L ++ Y    + E++RL+PPV    +        PDG  + KG  VT   YA+    ++W  P+  +   F P     +  F+P        F  G R C+GK  A+ E+K A    + +F + + DP + P   P L    S G+ + +++
Sbjct:  317 TFMFEGHDTTASGISWIFYALATHPEHQHRCREEIQGLLGDGAS-ITWEHLDQMPYTTMCIKEALRLYPPVPGVGRQLSSPVTFPDGRSLPKGVIVTLSIYALHHNPKVWPNPEVFDPFPFAPGSARHSHAFLP--------FSGGPRNCIGKQFAMNELKVAVALTLVRFEL-LPDPKRVPDQKPRLVLKSSNGIHLRLRK 508          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP4A5_RABIT (Cytochrome P450 4A5 OS=Oryctolagus cuniculus GN=CYP4A5 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.515e-15
Identity = 53/198 (26.77%), Postives = 94/198 (47.47%), Query Frame = -1

Query:  233 SFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRVSDPNQAPRFAPGLTATVSGGLPVMVQE 826
            +F+  G DT ASG++  F+ L+ H E +   R E   ++      +++E L ++ Y    + E+MRL+PPV   S+        PDG  + KG  VT   Y +     +W P+   F P R+        ++   +  F  G R C+GK  A+ E+K A    + +F + + DP + P+    L    + G+ + +++
Sbjct:  318 TFMFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGAS-ITWEHLDQMPYTTMCIKEAMRLYPPVPAISRDLSSPVTFPDGRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDPGRFTPGSA---RHSHAFLPFSGGARNCIGKQFAMNELKVAVALTLVRFEL-LPDPTRIPKPTARLVLKSNNGIHLRLRK 509          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP3AL_CALJA (Cytochrome P450 3A21 OS=Callithrix jacchus GN=CYP3A21 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.515e-15
Identity = 51/179 (28.49%), Postives = 95/179 (53.07%), Query Frame = -1

Query:  293 VSFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRVSDPNQAP 829
            + F+ AG +T +S L+   + L+ H +V+  ++ E D ++ PN+   +++ + ++ YL+  V E++RLFP      +  ++ D+  +G F+ KG  V    YA+    + W  +  +F PER+ +N      +P+ Y  F  G R C+G   AL+ MK A + V++ F+ +     Q P
Sbjct:  300 IIFIFAGYETTSSTLSFIMYELATHPDVQQKLQEEIDAVL-PNKAPATYDTVLQMEYLDMVVNETLRLFPLAMRLERVCKK-DVEINGVFIPKGVVVMIPSYALHYDPKYW-TEPEKFLPERFSKNNK-DNIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIP 474          

BLAST of CB290743 vs. ExPASy Swiss-Prot
Match: CP3A8_MACFA (Cytochrome P450 3A8 OS=Macaca fascicularis GN=CYP3A8 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.515e-15
Identity = 50/179 (27.93%), Postives = 96/179 (53.63%), Query Frame = -1

Query:  293 VSFLLAGRDTVASGLTSFFWLLSQHSEVESAIRNESDKIMKPNQDLVSFEQLRELHYLNAAVYESMRLFPPVQFDSKFAQEDDILPDGTFVRKGTRVTYHPYAMGRMERIWGPDCSEFKPERWLRNGTFVPQNPFKYPVFQAGHRVCLGKDMALVEMKSAALAVVRKFNIRVSDPNQAP 829
            + F+ AG +T +S L+   + L+ H +V+  ++ E D ++ PN+   +++ + ++ YL+  V E++R+F P+    +   + D+  +G F+ KG  V    YA+    + W P+  +F PER+ +       +P+ Y  F +G R C+G   AL+ MK A + V++ F+ +     Q P
Sbjct:  300 IIFIFAGYETTSSVLSFIIYELATHPDVQQKLQEEIDTVL-PNKAPPTYDTVLQMEYLDMVVNETLRIF-PIAMRLERVCKKDVEINGIFIPKGVVVMIPSYALHHDPKYW-PEPEKFLPERFSKKNN-DNIDPYIYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFSFKPCKETQIP 474