CB610685

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MP2K1_HUMAN (Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2)

HSP 1 Score: 153.68 bits (387), Expect = 1.148e-36
Identity = 83/191 (43.46%), Postives = 120/191 (62.83%), Query Frame = 2

Query:  203 DLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 772
            D EK+  LG GNGG V+KV H+ +  + A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L K G   E  L  ++  ++KGL+YL   HKI+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS
Sbjct:   67 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWS 248          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MP2K2_CANFA (Dual specificity mitogen-activated protein kinase kinase 2 OS=Canis familiaris GN=MAP2K2 PE=2 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 8.226e-35
Identity = 82/191 (42.93%), Postives = 119/191 (62.30%), Query Frame = 2

Query:  203 DLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 772
            D E++  LG GNGG V KVQHR +  I A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS
Sbjct:   71 DFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWS 252          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MP2K2_HUMAN (Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 1.833e-34
Identity = 81/191 (42.41%), Postives = 119/191 (62.30%), Query Frame = 2

Query:  203 DLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 772
            D E++  LG GNGG V KVQHR +  I A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YM+PER               DIWS
Sbjct:   71 DFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMAPERLQ-----GTHYSVQSDIWS 252          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MP2K2_CHICK (Dual specificity mitogen-activated protein kinase kinase 2 OS=Gallus gallus GN=MAP2K2 PE=2 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 1.833e-34
Identity = 81/191 (42.41%), Postives = 119/191 (62.30%), Query Frame = 2

Query:  203 DLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 772
            D E++  LG GNGG V KVQH+ +  I A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS
Sbjct:   69 DFERISELGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWS 250          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MEK2_CAEEL (Dual specificity mitogen-activated protein kinase kinase mek-2 OS=Caenorhabditis elegans GN=mek-2 PE=1 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 4.083e-34
Identity = 79/165 (47.88%), Postives = 113/165 (68.48%), Query Frame = 2

Query:  224 LGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPER 715
            LGHGNGG V K  HR T  I A K+VH +  P+VR+Q+ +E+ +L + +SPFIV  +G F   + DI+I MEYMD  +LD +L K G   E  +  I+  +++GL+YL    KI+HRD+KPSN+LVN+N  ++K+ DFGVS ++  S+   NS+VGT +YM+PER
Sbjct:   79 LGHGNGGVVNKCVHRKTGVIMARKLVHLEIKPSVRQQIVKELAVLHKCNSPFIVGFYGAF-VDNNDISICMEYMDGLSLDIVLKKVGRLPEKFVGRISVAVVRGLTYLKDEIKILHRDVKPSNMLVNSNG-EIKLCDFGVSGMLIDSM--ANSFVGTRSYMAPER 239          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MP2K2_RAT (Dual specificity mitogen-activated protein kinase kinase 2 OS=Rattus norvegicus GN=Map2k2 PE=2 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 5.332e-34
Identity = 81/191 (42.41%), Postives = 118/191 (61.78%), Query Frame = 2

Query:  203 DLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 772
            D E++  LG GNGG V K +HR +  I A K++H +  P VR Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS
Sbjct:   71 DFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWS 252          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MP2K2_MOUSE (Dual specificity mitogen-activated protein kinase kinase 2 OS=Mus musculus GN=Map2k2 PE=1 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 6.964e-34
Identity = 81/191 (42.41%), Postives = 118/191 (61.78%), Query Frame = 2

Query:  203 DLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 772
            D E++  LG GNGG V K +HR +  I A K++H +  P VR Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS
Sbjct:   71 DFERISELGAGNGGVVTKARHRPSGFIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWS 252          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: M2K1_ARATH (Mitogen-activated protein kinase kinase 1 OS=Arabidopsis thaliana GN=MKK1 PE=1 SV=2)

HSP 1 Score: 143.28 bits (360), Expect = 1.551e-33
Identity = 80/208 (38.46%), Postives = 122/208 (58.65%), Query Frame = 2

Query:  191 IAYSDLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYLHGHK-IIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHF 811
            ++ +DLE ++V+G G+ G V  V+H+ T + +ALKV+  + + +  R + +E+ I   +  P++V C+  F   +G ++I++E+MD G+L  LL K G   E  L+ I  ++L+GL Y+H  + IIHRD+KPSNLL+N+   +VKI DFGVSKI+  +    NS+VGT  YMSPER               DIWS          G F
Sbjct:   63 LSLADLEVIKVIGKGSSGNVQLVKHKLTQQFFALKVIQLNTEESTCRAISQELRINLSSQCPYLVSCYQSFYH-NGLVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHERRIIHRDLKPSNLLINHRG-EVKITDFGVSKILTSTSSLANSFVGTYPYMSPERIS-----GSLYSNKSDIWSLGLVLLECATGKF 263          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: MP2K2_CYPCA (Dual specificity mitogen-activated protein kinase kinase 2 OS=Cyprinus carpio GN=map2k2 PE=2 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 2.646e-33
Identity = 79/204 (38.73%), Postives = 120/204 (58.82%), Query Frame = 2

Query:  203 DLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHF 811
            D + +  LG GNGG V+KV+H+ +  + A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               D+WS          G F
Sbjct:   68 DFDPICELGAGNGGVVHKVRHKPSRLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEARRIPEEILGKVSIAVLRGLVYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDVWSMGLSLVELAIGRF 262          

BLAST of CB610685 vs. ExPASy Swiss-Prot
Match: M2K1_ORYSJ (Mitogen-activated protein kinase kinase 1 OS=Oryza sativa subsp. japonica GN=MEK1 PE=1 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 1.006e-32
Identity = 82/208 (39.42%), Postives = 120/208 (57.69%), Query Frame = 2

Query:  191 IAYSDLEKLQVLGHGNGGTVYKVQHRCTLKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHIASQILKGLSYLHGHK-IIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHF 811
            ++  DLE +QV+G G+GG V  V+H+    +YALK +  +    VR+Q+ +E++I + T +  IV C   F   +G I +++EYMD G+L  ++ +  T  EP LA +  Q+L+GL YLH  + +IHRDIKPSNLLVN    +VKI DFGVS ++  S+   +++VGT  YM+PER               DIWS          G F
Sbjct:   66 LSMDDLEMIQVIGKGSGGIVQLVRHKWVGTLYALKGIQMNIQEAVRKQIVQELKINQATQNAHIVLCHQSFYH-NGVIYLVLEYMDRGSLADIIKQVKTILEPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNLLVNRKG-EVKITDFGVSAVLASSMGQRDTFVGTYNYMAPERIS-----GSSYDYKSDIWSLGLVILECAIGRF 266