CF417199

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: SSN3_ASPCL (Serine/threonine-protein kinase ssn3 OS=Aspergillus clavatus GN=ssn3 PE=3 SV=2)

HSP 1 Score: 83.9593 bits (206), Expect = 1.420e-24
Identity = 68/207 (32.85%), Postives = 101/207 (48.79%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKA--KDKATGQLVALKKTRLEMDEE-----GIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKS-YTHE--IVTLWYR 599
            +KY  +  +  GTYG+VYKA  KD   G+  A+KK + + + E     G+  +A+RE+SL   L  S  VV+L  +   D  +                       ++VFEY + DL + I  H + P    +P  +I+S L+QL  G+ + H++ VLHRDLKP N               GL R F  PL S Y+ +  +VT+WYR
Sbjct:   39 DKYHIVGFISSGTYGRVYKAIGKDGRKGEF-AIKKFKPDKEGEIIQYTGLSQSAIREMSLCSELDHS-NVVQLAEIILEDKCI-----------------------FMVFEYTEHDLLQIIHHHTQ-PQRHAIPAPMIKSILFQLLNGLLYLHTNWVLHRDLKPAN-ILVTSSGAVRIGDLGLARLFYKPLNSLYSGDKVVVTIWYR 218          

HSP 2 Score: 49.2914 bits (116), Expect = 1.420e-24
Identity = 19/28 (67.86%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+L+GS HY+ AVD+W+VGCIFAE++
Sbjct:  219 APELLMGSRHYTPAVDLWAVGCIFAELL 246          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: BUR1_YARLI (Serine/threonine-protein kinase BUR1 OS=Yarrowia lipolytica GN=BUR1 PE=3 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 2.385e-24
Identity = 64/208 (30.77%), Postives = 97/208 (46.63%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRL-LCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVP----------LKSYTHEIVTLWYR 599
            E Y+ L K+GEGT+G+V++A+   T + VALKK  L  ++EG P TALRE+ +L++L     +  + L VE  D S K                  +  +Y+V  Y+D DL   +     G     L P  I+ ++ QL +G+ + H+   LHRD+K  N               GL R +  P           ++ T  +VT WYR
Sbjct:   36 ESYKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLRHENVIPLVDLAVERGDQSKKE-----------------RGCVYMVTPYMDHDLAGLL-----GNQSVQLSPAHIKCYMLQLLEGIGYLHAKKFLHRDIKAAN-ILVNDQGILKLADFGLARGYDGPAPNSQTAGVNTENLTAMVVTRWYR 220          

HSP 2 Score: 43.5134 bits (101), Expect = 2.385e-24
Identity = 15/30 (50.00%), Postives = 22/30 (73.33%), Query Frame = 1

Query:  604 PEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            PE++LG   Y+TA+DMW +GC+F E   R+
Sbjct:  222 PELILGDRKYTTAIDMWGIGCVFGEFFTRK 251          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CTK1_YEAST (CTD kinase subunit alpha OS=Saccharomyces cerevisiae GN=CTK1 PE=1 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 3.119e-24
Identity = 61/196 (31.12%), Postives = 93/196 (47.45%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQ-SLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            Y ++ +VGEGTYGKVYKAK+  T +LVALKK RL+ + EG P T++RE+ LLQ     ++  ++ + VE                         +  +Y++FEY D DL   + +         +  +  +    QL  G+ + H + +LHRD+K  N               GL R        YT+ ++TLWYR
Sbjct:  183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVE------------------------SQKTVYMIFEYADNDLSGLLLNKEV-----QISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSN-ILIDNQGNLKITDFGLARKMN-SRADYTNRVITLWYR 347          

HSP 2 Score: 41.2022 bits (95), Expect = 3.119e-24
Identity = 15/29 (51.72%), Postives = 21/29 (72.41%), Query Frame = 1

Query:  604 PEVLLGSTHYSTAVDMWSVGCIFAEMVKR 690
            PE+LLG+T+Y T VDMW  GC+  E+  +
Sbjct:  349 PELLLGTTNYGTEVDMWGCGCLLVELFNK 377          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: BUR1_GIBZE (Serine/threonine-protein kinase BUR1 OS=Gibberella zeae GN=BUR1 PE=3 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 6.886e-24
Identity = 68/212 (32.08%), Postives = 106/212 (50.00%), Query Frame = 3

Query:    3 RMEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRL--LCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFT-------VPL----KSYTHEIVTLWYR 599
            R+  YE L K+GEGT+G+V++A+ + TG LVALKK  +  +++G P TALRE+ LL++LS    ++RL  + +EH                   T    K  +Y+   Y+D DL   +D+    P+ +   P  I+ ++ QL +G+ + H   +LHRD+K  N               GL R +        VP+    + YT  +VT WYR
Sbjct:   33 RISDYELLGKLGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLLSHK-NILRLEDMAIEHPTRQ---------------TDKRKKPIVYMATPYMDHDLSGLLDN----PSVQFKEPQ-IKCYMLQLLEGLRYLHDSRILHRDMKAAN-LLINNKGILQIADFGLARHYDGRTPESGVPMGEGKRDYTGLVVTRWYR 222          

HSP 2 Score: 38.1206 bits (87), Expect = 6.886e-24
Identity = 14/27 (51.85%), Postives = 20/27 (74.07%), Query Frame = 1

Query:  604 PEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            PE+LL    Y+ A+D+W VGC+F EM+
Sbjct:  224 PELLLQLRQYTPAIDVWGVGCVFGEML 250          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK12_CAEEL (Putative cell division protein kinase 12 OS=Caenorhabditis elegans GN=cdtl-7 PE=3 SV=4)

HSP 1 Score: 110.538 bits (275), Expect = 8.555e-24
Identity = 70/195 (35.90%), Postives = 102/195 (52.31%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            Y  L+++GEGTYG+VYKA +  TG+ VALK+ RLE ++EG P TA+RE+ +L+ L     +VRL+ +   D S+                   ++N YLVFEY+D DL   ++S              I S   QL +G+A+ H+ G LHRD+K  N               GL R +    + YT+ ++TLWYR
Sbjct:  311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHK-NIVRLMDIVIDDISMDE-------------LKRTRANFYLVFEYVDHDLIGLLESKEL----VDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSN-ILVNNKGELKIADLGLARLWEKESRLYTNRVITLWYR 486          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: SSN3_EMENI (Serine/threonine-protein kinase ssn3 OS=Emericella nidulans GN=ssn3 PE=3 SV=2)

HSP 1 Score: 81.2629 bits (199), Expect = 8.978e-24
Identity = 62/206 (30.10%), Postives = 97/206 (47.09%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKAKDK-ATGQLVALKKTRLEMDEE-----GIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSY---THEIVTLWYR 599
            +KY  +  +  GTYG+VYKA  +   G   A+KK + + + +     G+  +A+RE++L   L  +  VV+L  +   D  +                       ++VFEY + DL + I  H + P   P+P  +++S L+QL  G+ + H++ VLHRDLKP N               GL R F  PL S       +VT+WYR
Sbjct:   37 DKYHIVGFISSGTYGRVYKAVGRNGQGGEFAIKKFKPDKEGDIIQYTGLSQSAIREMALCSELDHA-NVVQLAEIILEDKCI-----------------------FMVFEYTEHDLLQIIHHHTQ-PQRHPIPAAMVRSILFQLLNGLLYLHTNWVLHRDLKPAN-ILVTSSGAIRIGDLGLARLFYKPLNSLFSGDKVVVTIWYR 216          

HSP 2 Score: 49.2914 bits (116), Expect = 8.978e-24
Identity = 19/28 (67.86%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+L+GS HY+ AVD+W+VGCIFAE++
Sbjct:  217 APELLMGSRHYTPAVDLWAVGCIFAELL 244          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_DROME (Cell division protein kinase 8 OS=Drosophila melanogaster GN=Cdk8 PE=1 SV=2)

HSP 1 Score: 82.4185 bits (202), Expect = 1.167e-23
Identity = 67/201 (33.33%), Postives = 94/201 (46.77%), Query Frame = 3

Query:   30 KVGEGTYGKVYKAKDKAT--GQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRP---LPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN---XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            KVG GTYG VYKAK K T  G+  ALK    ++D  G+  +A RE++LL+ L     V+ L+ V                   F + N+ K  ++L+ +Y + DL   I  HR     +    +P  +++S LYQ+  G+ + HS+ VLHRDLKP N                  G  R F  PLK        +VT WYR
Sbjct:   26 KVGRGTYGHVYKAKWKETSDGKEYALK----QIDGTGLSMSACREIALLRELKHQ-NVITLIRV-------------------FLSHNDRK--VFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYR 200          

HSP 2 Score: 47.7506 bits (112), Expect = 1.167e-23
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  201 APELLLGARHYTKAIDIWAIGCIFAELL 228          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDKL5_HUMAN (Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 1.498e-23
Identity = 61/198 (30.81%), Postives = 92/198 (46.46%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M K+E L  VGEG YG V K + K T ++VA+KK +   + E +  T LRE+ +L+ L Q   V            LK            A    GK  LYLVFEY++ ++ + ++       P  +PP  ++S++YQL K +  CH + ++HRD+KP+N                          +YT  + T WYR
Sbjct:   10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIV-----------ELKE-----------AFRRRGK--LYLVFEYVEKNMLELLEE-----MPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYR 178          

HSP 2 Score: 36.5798 bits (83), Expect = 1.498e-23
Identity = 16/27 (59.26%), Postives = 21/27 (77.78%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            +PE+LLG+  Y  +VDMWSVGCI  E+
Sbjct:  179 SPELLLGAP-YGKSVDMWSVGCILGEL 204          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDKL5_MOUSE (Cyclin-dependent kinase-like 5 OS=Mus musculus GN=Cdkl5 PE=2 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 1.500e-23
Identity = 61/198 (30.81%), Postives = 92/198 (46.46%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M K+E L  VGEG YG V K + K T ++VA+KK +   + E +  T LRE+ +L+ L Q   V            LK            A    GK  LYLVFEY++ ++ + ++       P  +PP  ++S++YQL K +  CH + ++HRD+KP+N                          +YT  + T WYR
Sbjct:   10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIV-----------ELKE-----------AFRRRGK--LYLVFEYVEKNMLELLEE-----MPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYR 178          

HSP 2 Score: 36.5798 bits (83), Expect = 1.500e-23
Identity = 16/27 (59.26%), Postives = 21/27 (77.78%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            +PE+LLG+  Y  +VDMWSVGCI  E+
Sbjct:  179 SPELLLGAP-YGKSVDMWSVGCILGEL 204          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: SSN3_NEOFI (Serine/threonine-protein kinase ssn3 OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) GN=ssn3 PE=3 SV=1)

HSP 1 Score: 80.4925 bits (197), Expect = 1.520e-23
Identity = 64/202 (31.68%), Postives = 100/202 (49.50%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKA--KDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKS-YTHE--IVTLWYR 599
            +KY  +  +  GTYG+VYKA  KD   G+  A+KK + + + E I  T L + ++ +M          LC E        ++P+    +     +     +++VFEY + DL + I  H + P    +P  +I+S L+QL  G+ + H++ VLHRDLKP N               GL R F  PL S Y+ +  +VT+WYR
Sbjct:   39 DKYHIVGFISSGTYGRVYKAIGKDGRKGEY-AIKKFKPDKEGEIIQYTGLSQSAIREMA---------LCSE-------LDHPNVVQLAEIILEDKC---IFMVFEYTEHDLLQIIHHHTQ-PQRHAIPAPMIKSILFQLLNGLLYLHTNWVLHRDLKPAN-ILVTSSGAVRIGDLGLARLFYKPLNSLYSGDKVVVTIWYR 218          

HSP 2 Score: 49.2914 bits (116), Expect = 1.520e-23
Identity = 19/28 (67.86%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+L+GS HY+ AVD+W+VGCIFAE++
Sbjct:  219 APELLMGSRHYTPAVDLWAVGCIFAELL 246