CF417199

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: SSN3_ASPNC (Serine/threonine-protein kinase ssn3 OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=ssn3 PE=3 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 1.249e-22
Identity = 61/200 (30.50%), Postives = 92/200 (46.00%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSY---THEIVTLWYR 599
            ++Y  +  +  GTYG+VYKA  K  GQ       + + D+EG       E+     LSQS      LC E        ++P+    +     +     +++VFEY + DL + I  H + P    +P  +++S L+QL  G+ + H++ VLHRDLKP N               GL R F  PL S       +VT+WYR
Sbjct:   38 DRYHIVGFISSGTYGRVYKAIGK-NGQKGEFAIKKFKPDKEG-------EIIQYTGLSQSAIREMALCSE-------LDHPNVVQLAEIILEDKC---IFMVFEYTEHDLLQIIHHHTQ-PQRHAIPALMVRSILFQLLNGLLYLHTNWVLHRDLKPAN-ILVTSSGAIRIGDLGLARLFYKPLNSLFSGDKVVVTIWYR 217          

HSP 2 Score: 49.2914 bits (116), Expect = 1.249e-22
Identity = 19/28 (67.86%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+L+GS HY+ AVD+W+VGCIFAE++
Sbjct:  218 APELLMGSRHYTPAVDLWAVGCIFAELL 245          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_MOUSE (Cell division protein kinase 8 OS=Mus musculus GN=Cdk8 PE=2 SV=3)

HSP 1 Score: 78.5666 bits (192), Expect = 1.622e-22
Identity = 67/203 (33.00%), Postives = 90/203 (44.33%), Query Frame = 3

Query:   30 KVGEGTYGKVYKAK--DKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCV--EHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGP---NPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN---XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            KVG GTYG VYKAK  D    +  ALK    +++  GI  +A RE++LL+ L     V+ LL V   H D  +                       +L+F+Y + DL   I  HR       P  LP  +++S LYQ+  G+ + H++ VLHRDLKP N                  G  R F  PLK        +VT WYR
Sbjct:   26 KVGRGTYGHVYKAKRKDGKDDKDYALK----QIEGTGISMSACREIALLRELKHP-NVISLLKVFLSHADRKV-----------------------WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYR 200          

HSP 2 Score: 47.7506 bits (112), Expect = 1.622e-22
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  201 APELLLGARHYTKAIDIWAIGCIFAELL 228          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_HUMAN (Cell division protein kinase 8 OS=Homo sapiens GN=CDK8 PE=1 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 1.622e-22
Identity = 63/202 (31.19%), Postives = 91/202 (45.05%), Query Frame = 3

Query:   30 KVGEGTYGKVYKAK--DKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQ-SLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGP---NPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN---XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            KVG GTYG VYKAK  D    +  ALK    +++  GI  +A RE++LL+ L   ++  ++ + + H D  +                       +L+F+Y + DL   I  HR       P  LP  +++S LYQ+  G+ + H++ VLHRDLKP N                  G  R F  PLK        +VT WYR
Sbjct:   26 KVGRGTYGHVYKAKRKDGKDDKDYALK----QIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKV-----------------------WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYR 200          

HSP 2 Score: 47.7506 bits (112), Expect = 1.622e-22
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  201 APELLLGARHYTKAIDIWAIGCIFAELL 228          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_AEDAE (Cell division protein kinase 8 OS=Aedes aegypti GN=Cdk8 PE=3 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 3.568e-22
Identity = 64/201 (31.84%), Postives = 91/201 (45.27%), Query Frame = 3

Query:   30 KVGEGTYGKVYKAKDKATGQL--VALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGP---NPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN---XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            KVG GTYG VYKA  K +      ALK    +++  G+  +A RE++LL+ L     V+ L+ V                   F +  + K  ++L+F+Y + DL   I  HR       P  +P  +++S LYQ+  G+ + HS+ VLHRDLKP N                  G  R F  PLK        +VT WYR
Sbjct:   26 KVGRGTYGHVYKAHRKESNDTKDYALK----QIEGTGLSMSACREIALLRELKHP-NVINLIRV-------------------FLSHTDRK--VWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYR 200          

HSP 2 Score: 47.7506 bits (112), Expect = 3.568e-22
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  201 APELLLGARHYTKAIDIWAIGCIFAELL 228          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_CAEBR (Cell division protein kinase 8 OS=Caenorhabditis briggsae GN=cdk-8 PE=3 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 4.625e-22
Identity = 60/207 (28.99%), Postives = 93/207 (44.93%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDE-EGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPN---PRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN-----XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            +E  +++G GTYG VYKA  K +      K+  L+M E +G   +A RE++L + L        L+C++ V                F T+   +  ++L+ +Y + DL   I  HR       P  +P  ++++ L+Q+  G+ + HS+ VLHRDLKP N                    G  R F  PLK        +VT WYR
Sbjct:   23 FENSKEIGRGTYGLVYKAVPKHSNGRFPNKEYALKMIEGQGFSMSACREIALFRELRHP----NLICLQRV----------------FLTN---EKKVWLLLDYAEHDLWHVIKHHRTAKTKKVPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGGPDMRGRVKIADLGFSRIFANPLKPMAELDPVVVTFWYR 206          

HSP 2 Score: 47.7506 bits (112), Expect = 4.625e-22
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  207 APELLLGAKHYTKAIDVWAIGCIFAELL 234          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_XENTR (Cell division protein kinase 8 OS=Xenopus tropicalis GN=cdk8 PE=2 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 4.648e-22
Identity = 62/202 (30.69%), Postives = 91/202 (45.05%), Query Frame = 3

Query:   30 KVGEGTYGKVYKAK--DKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQ-SLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGP---NPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN---XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            KVG GTYG VYKAK  D    +  ALK    +++  GI  +A RE++LL+ L   ++  ++ + + H D  +                       +L+F++ + DL   I  HR       P  LP  +++S LYQ+  G+ + H++ VLHRDLKP N                  G  R F  PLK        +VT WYR
Sbjct:   26 KVGRGTYGHVYKAKRKDGRDDRDYALK----QIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKV-----------------------WLLFDFAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYR 200          

HSP 2 Score: 47.7506 bits (112), Expect = 4.648e-22
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  201 APELLLGARHYTKAIDIWAIGCIFAELL 228          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: Y7597_DROME (Cell division cycle 2-like protein kinase CG7597 OS=Drosophila melanogaster GN=CG7597 PE=1 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 6.131e-22
Identity = 68/200 (34.00%), Postives = 99/200 (49.50%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVP--LKSYTHEIVTLWYR 599
            ++ +E + ++GEGTYG+VYKA+D  T  +VALKK RLE ++EG P TA+RE+ +L+ L+    V           +L         A  F      K + YLVFEY+D DL   ++S     N          S + QL  G+ +CH    LHRD+K  N               GL R +      + YT++++TLWYR
Sbjct:  801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIV-----------NLHEIVTDKQDAVEF---RKDKGSFYLVFEYMDHDLMGLLESGMVDFNEEN-----NASIMKQLLDGLNYCHKKNFLHRDIKCSN-ILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYR 980          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MPK5_ARATH (Mitogen-activated protein kinase 5 OS=Arabidopsis thaliana GN=MPK5 PE=2 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 7.901e-22
Identity = 60/192 (31.25%), Postives = 84/192 (43.75%), Query Frame = 3

Query:   24 LEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            +  +G G YG V  A D  T + +A+KK     D +      LRE+ LL+ L            EH +  +  +   P     F        ++Y+VFE +DTDL + I S++       L     Q FLYQ+ +G+ + HS  VLHRDLKP N               GL R  T   +  T  +VT WYR
Sbjct:   46 IRPIGRGAYGFVCAAVDSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHL------------EHENVVVIKDIIRPPKKEDFV-------DVYIVFELMDTDLHQIIRSNQS------LNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSN-LLLNSNCDLKITDFGLART-TSETEYMTEYVVTRWYR 210          

HSP 2 Score: 48.521 bits (114), Expect = 7.901e-22
Identity = 19/31 (61.29%), Postives = 28/31 (90.32%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE+LL S+ Y++A+D+WSVGCIFAE++ R+
Sbjct:  211 APELLLNSSEYTSAIDVWSVGCIFAEIMTRE 241          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_CAEEL (Cell division protein kinase 8 OS=Caenorhabditis elegans GN=cdk-8 PE=2 SV=4)

HSP 1 Score: 75.8702 bits (185), Expect = 1.019e-21
Identity = 59/207 (28.50%), Postives = 93/207 (44.93%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDE-EGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPN---PRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN-----XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            +E  +++G GTYG VYKA  K        K+  L+M E +G   +A RE++L + L        L+C++ V                F T+   +  ++L+ +Y + DL   I  HR   +   P  +P  ++++ L+Q+  G+ + HS+ VLHRDLKP N                    G  R +  PLK        +VT WYR
Sbjct:   26 FENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMIEGQGFSMSACREIALFRELRHP----NLICLQRV----------------FLTN---EKKVWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVTFWYR 209          

HSP 2 Score: 47.7506 bits (112), Expect = 1.019e-21
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  210 APELLLGAKHYTKAIDVWAIGCIFAELL 237          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK8_DANRE (Cell division protein kinase 8 OS=Danio rerio GN=cdk8 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 1.023e-21
Identity = 62/202 (30.69%), Postives = 90/202 (44.55%), Query Frame = 3

Query:   30 KVGEGTYGKVYKAK--DKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQ-SLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGP---NPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN---XXXXXXXXXXXXXXXGLGRAFTVPLKSYTH---EIVTLWYR 599
            KVG GTYG VYKAK  D    +  ALK    +++  GI  +A RE++LL+ L   ++  ++ + + H D  +                       +L+F+Y + DL   I  HR       P  LP  +++S LYQ+  G+ + H++ VLHRDLKP N                  G  R    PLK        +VT WYR
Sbjct:   26 KVGRGTYGHVYKAKRKDGKDDRDYALK----QIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKV-----------------------WLLFDYAEHDLWHIIKFHRASKANKKPLQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLSNSPLKPLADLDPVVVTFWYR 200          

HSP 2 Score: 47.7506 bits (112), Expect = 1.023e-21
Identity = 17/28 (60.71%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+ A+D+W++GCIFAE++
Sbjct:  201 APELLLGARHYTKAIDIWAIGCIFAELL 228