CF417199

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK20_MACMU (Cell division protein kinase 20 OS=Macaca mulatta GN=CDK20 PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 5.738e-20
Identity = 66/195 (33.85%), Postives = 97/195 (49.74%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVP-LKSYTHEIVT 587
            M++Y  L ++GEG +G V+KAK   TG++VALKK  L   E+G P  ALRE+  LQ +  + YVV+L  V                       + G     L FE++ +DL + +   +     RPL    ++S+L  L KGVA CH++ ++HRDLKP N               GL R F+    + YTH++ T
Sbjct:    1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGDNQYVVQLKAV---------------------FPHGG--GFVLAFEFMLSDLAEVVRHAQ-----RPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPAN-LLISASGQLKIADFGLARVFSPDGSRLYTHQVAT 166          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK12_MOUSE (Mitogen-activated protein kinase 12 OS=Mus musculus GN=Mapk12 PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 6.910e-20
Identity = 62/195 (31.79%), Postives = 83/195 (42.56%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            Y+ L+ VG G YG V  A D  TG  VA+KK       E     A RE+ LL+ +     V+ LL V   D SL                 +  ++ YLV  ++ TDL K +           L    IQ  +YQ+ KG+ + H+ GV+HRDLKP N               GL R     +  Y   +VT WYR
Sbjct:   27 YQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE-NVIGLLDVFTPDESL-----------------DDFTDFYLVMPFMGTDLGKLM-------KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGN-LAVNEDCELKILDFGLARQADSEMTGY---VVTRWYR 192          

HSP 2 Score: 41.5874 bits (96), Expect = 6.910e-20
Identity = 17/32 (53.12%), Postives = 23/32 (71.88%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQV 696
            APEV+L    Y+  VD+WSVGCI AEM+  ++
Sbjct:  193 APEVILNWMRYTQTVDIWSVGCIMAEMITGKI 224          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: ICK_HUMAN (Serine/threonine-protein kinase ICK OS=Homo sapiens GN=ICK PE=1 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 8.887e-20
Identity = 59/200 (29.50%), Postives = 93/200 (46.50%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMD--EEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M +Y  + ++G+GTYG V   +   +G+L+A+KK + +    EE +    LREV  L+ L+ +  VV+L  V      ++ N+                 +LY +FEY+  +L + I    K       P + I++ +YQ+ +G+A  H HG  HRDLKP+N               GL R        YT  + T WYR
Sbjct:    1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMN---LREVKSLKKLNHA-NVVKLKEV------IREND-----------------HLYFIFEYMKENLYQLIKERNK-----LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPEN-LLCMGPELVKIADFGLAREIR-SKPPYTDYVSTRWYR 166          

HSP 2 Score: 43.8986 bits (102), Expect = 8.887e-20
Identity = 18/27 (66.67%), Postives = 24/27 (88.89%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APEVLL ST+YS+ +D+W+VGCI AE+
Sbjct:  167 APEVLLRSTNYSSPIDVWAVGCIMAEV 193          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: ICK_RAT (Serine/threonine-protein kinase ICK OS=Rattus norvegicus GN=Ick PE=1 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 8.888e-20
Identity = 58/200 (29.00%), Postives = 94/200 (47.00%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMD--EEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M +Y  ++++G+GTYG V   +   +G+L+A+KK + +    EE +    LREV  L+ L+ +  +V+L  V      ++ N+                 +LY +FEY+  +L + I    K       P + I++ +YQ+ +G+A  H HG  HRDLKP+N               GL R        YT  + T WYR
Sbjct:    1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMN---LREVKSLKKLNHA-NIVKLKEV------IREND-----------------HLYFIFEYMKENLYQLIKERNK-----LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPEN-LLCMGPELVKIADFGLAREIR-SRPPYTDYVSTRWYR 166          

HSP 2 Score: 43.8986 bits (102), Expect = 8.888e-20
Identity = 18/27 (66.67%), Postives = 24/27 (88.89%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APEVLL ST+YS+ +D+W+VGCI AE+
Sbjct:  167 APEVLLRSTNYSSPIDVWAVGCIMAEV 193          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: ICK_MOUSE (Serine/threonine-protein kinase ICK OS=Mus musculus GN=Ick PE=2 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 8.888e-20
Identity = 58/200 (29.00%), Postives = 94/200 (47.00%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMD--EEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M +Y  ++++G+GTYG V   +   +G+L+A+KK + +    EE +    LREV  L+ L+ +  +V+L  V      ++ N+                 +LY +FEY+  +L + I    K       P + I++ +YQ+ +G+A  H HG  HRDLKP+N               GL R        YT  + T WYR
Sbjct:    1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMN---LREVKSLKKLNHA-NIVKLKEV------IREND-----------------HLYFIFEYMKENLYQLIKERNK-----LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPEN-LLCMGPELVKIADFGLAREIR-SRPPYTDYVSTRWYR 166          

HSP 2 Score: 43.8986 bits (102), Expect = 8.888e-20
Identity = 18/27 (66.67%), Postives = 24/27 (88.89%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APEVLL ST+YS+ +D+W+VGCI AE+
Sbjct:  167 APEVLLRSTNYSSPIDIWAVGCIMAEV 193          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: HOG1_BLUGR (Mitogen-activated protein kinase HOG1 OS=Blumeria graminis GN=HOG1 PE=3 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 8.993e-20
Identity = 55/158 (34.81%), Postives = 72/158 (45.57%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +Y  L+ VG G +G V  AKD  TGQ VA+KK         +     RE+ LL+ L     +           SL     SP              ++Y V E L TDL + + S       RPL    IQ FLYQ+ +G+ + HS GV+HRDLKP N
Sbjct:   19 RYSDLQPVGMGAFGLVCSAKDNLTGQNVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENVI-----------SLSDIFISP------------LEDIYFVTELLGTDLHRLLTS-------RPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSN 146          

HSP 2 Score: 39.6614 bits (91), Expect = 8.993e-20
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVK 687
            APE++L    Y   VD+WS GCIFAEM++
Sbjct:  181 APEIMLTWQKYDVEVDIWSAGCIFAEMLE 209          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: BUR1_KLULA (Serine/threonine-protein kinase BUR1 OS=Kluyveromyces lactis GN=BUR1 PE=3 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 1.155e-19
Identity = 53/218 (24.31%), Postives = 98/218 (44.95%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGK-------SNLYLVFEYLDTDLKKFIDSHRKGPNPR-PLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAF---TVPLK---------SYTHEIVTLWYR 599
            +  Y + EK+G+GT+G+V+K     T + VA+K+  +  +++  P TA RE+++L+ ++    V  +  V     + K+++ SP     +  +N           + +++  Y+ +DL   +       NPR       +++ + QL +G+ + H +  LHRD+K  N               GL R +      LK          YT  +VT WYR
Sbjct:   52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH------NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTAN-ILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYR 262          

HSP 2 Score: 48.9062 bits (115), Expect = 1.155e-19
Identity = 17/31 (54.84%), Postives = 26/31 (83.87%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE++LG  HY+TAVD+W +GC+FAE  +++
Sbjct:  263 APEIVLGDRHYTTAVDIWGIGCVFAEFFEKK 293          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: NTF4_TOBAC (Mitogen-activated protein kinase homolog NTF4 OS=Nicotiana tabacum GN=NTF4 PE=2 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 1.167e-19
Identity = 58/189 (30.69%), Postives = 84/189 (44.44%), Query Frame = 3

Query:   33 VGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            +G+G YG V  A +  T + VA+KK     D +      LRE+ LL+ +     V           +++   P P    AF       +++Y+ +E +DTDL + I S++       L     Q FLYQ+ +G+ + HS  VLHRDLKP N               GL R  T      T  +VT WYR
Sbjct:   66 IGKGAYGIVCSALNSETNEHVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIV-----------AIRDIIPPPQR-EAF-------NDVYIAYELMDTDLHQIIRSNQG------LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSN-LLLNANCDLKICDFGLARV-TSETDFMTEYVVTRWYR 227          

HSP 2 Score: 45.8246 bits (107), Expect = 1.167e-19
Identity = 18/31 (58.06%), Postives = 26/31 (83.87%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE+LL S+ Y+ A+D+WSVGCIF E++ R+
Sbjct:  228 APELLLNSSDYTAAIDVWSVGCIFMELMDRK 258          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK12_RAT (Mitogen-activated protein kinase 12 OS=Rattus norvegicus GN=Mapk12 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 1.520e-19
Identity = 61/195 (31.28%), Postives = 83/195 (42.56%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            Y+ L+ VG G YG V  A D  TG  VA+KK       E     A RE+ LL+ +     V+ LL V   D +L                 +  ++ YLV  ++ TDL K +           L    IQ  +YQ+ KG+ + H+ GV+HRDLKP N               GL R     +  Y   +VT WYR
Sbjct:   27 YQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE-NVIGLLDVFTPDETL-----------------DDFTDFYLVMPFMGTDLGKLM-------KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGN-LAVNEDCELKILDFGLARQADSEMTGY---VVTRWYR 192          

HSP 2 Score: 41.5874 bits (96), Expect = 1.520e-19
Identity = 17/32 (53.12%), Postives = 23/32 (71.88%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQV 696
            APEV+L    Y+  VD+WSVGCI AEM+  ++
Sbjct:  193 APEVILNWMRYTQTVDIWSVGCIMAEMITGKI 224          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK07_MOUSE (Mitogen-activated protein kinase 7 OS=Mus musculus GN=Mapk7 PE=1 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.946e-19
Identity = 58/201 (28.86%), Postives = 88/201 (43.78%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAF-TVPLKS---YTHEIVTLWYR 599
            ++YE +E +G G YG V  A+ + TGQ VA+KK     D        LRE+ +L+       +        +   LK   P  +  S           +Y+V + +++DL + I S +      PL    ++ FLYQL +G+ + HS  V+HRDLKP N               G+ R   T P +     T  + T WYR
Sbjct:   53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIA-------IKDILKPTVPYGEFRS-----------VYVVLDLMESDLHQIIHSSQ------PLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSN-LLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228          

HSP 2 Score: 43.5134 bits (101), Expect = 1.946e-19
Identity = 17/31 (54.84%), Postives = 24/31 (77.42%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE++L    Y+ A+D+WSVGCIF EM+ R+
Sbjct:  229 APELMLSLHEYTQAIDLWSVGCIFGEMLARR 259