CF417199

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK06_MOUSE (Mitogen-activated protein kinase 6 OS=Mus musculus GN=Mapk6 PE=1 SV=3)

HSP 1 Score: 70.0922 bits (170), Expect = 5.923e-18
Identity = 58/205 (28.29%), Postives = 91/205 (44.39%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHE------IVTLWYRGSR 608
            +Y  L+ +G G  G V+ A D    + VA+KK  L  D + +   ALRE+ +++ L            +++    +   PS    +    S    +++Y+V EY++TDL   ++         PL     + F+YQL +G+ + HS  VLHRDLKP N               GL R        Y+H+      +VT WYR  R
Sbjct:   19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT-DPQSVKH-ALREIKIIRRLDH----------DNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-------PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMD---PHYSHKGHLSEGLVTKWYRSPR 201          

HSP 2 Score: 40.817 bits (94), Expect = 5.923e-18
Identity = 15/28 (53.57%), Postives = 22/28 (78.57%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            +P +LL   +Y+ A+DMW+ GCIFAEM+
Sbjct:  199 SPRLLLSPNNYTKAIDMWAAGCIFAEML 226          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK06_HUMAN (Mitogen-activated protein kinase 6 OS=Homo sapiens GN=MAPK6 PE=1 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 5.923e-18
Identity = 58/205 (28.29%), Postives = 91/205 (44.39%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHE------IVTLWYRGSR 608
            +Y  L+ +G G  G V+ A D    + VA+KK  L  D + +   ALRE+ +++ L            +++    +   PS    +    S    +++Y+V EY++TDL   ++         PL     + F+YQL +G+ + HS  VLHRDLKP N               GL R        Y+H+      +VT WYR  R
Sbjct:   19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT-DPQSVKH-ALREIKIIRRLDH----------DNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-------PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMD---PHYSHKGHLSEGLVTKWYRSPR 201          

HSP 2 Score: 40.817 bits (94), Expect = 5.923e-18
Identity = 15/28 (53.57%), Postives = 22/28 (78.57%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            +P +LL   +Y+ A+DMW+ GCIFAEM+
Sbjct:  199 SPRLLLSPNNYTKAIDMWAAGCIFAEML 226          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MAK_HUMAN (Serine/threonine-protein kinase MAK OS=Homo sapiens GN=MAK PE=2 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 5.940e-18
Identity = 57/201 (28.36%), Postives = 93/201 (46.27%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEM---DEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M +Y  + ++G+GTYG V   K   +G+LVA+K+ + +    DE       LREV  L+ L+ +  V++L  V      ++ N+                 +LY +FEY+  +L + +    K       P ++I++ +YQ+ +G+A  H HG  HRD+KP+N               GL R        YT  + T WYR
Sbjct:    1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDE----CMNLREVKSLKKLNHA-NVIKLKEV------IREND-----------------HLYFIFEYMKENLYQLMKDRNK-----LFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPEN-LLCMGPELVKIADFGLARELR-SQPPYTDYVSTRWYR 166          

HSP 2 Score: 37.3502 bits (85), Expect = 5.940e-18
Identity = 16/27 (59.26%), Postives = 22/27 (81.48%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APEVLL S+ YS+ +D+W+VG I AE+
Sbjct:  167 APEVLLRSSVYSSPIDVWAVGSIMAEL 193          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MAK_RAT (Serine/threonine-protein kinase MAK OS=Rattus norvegicus GN=Mak PE=2 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 5.941e-18
Identity = 57/201 (28.36%), Postives = 93/201 (46.27%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEM---DEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M +Y  + ++G+GTYG V   K   +G+LVA+K+ + +    DE       LREV  L+ L+ +  V++L  V      ++ N+                 +LY +FEY+  +L + +    K       P ++I++ +YQ+ +G+A  H HG  HRD+KP+N               GL R        YT  + T WYR
Sbjct:    1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDE----CMNLREVKSLKKLNHA-NVIKLKEV------IREND-----------------HLYFIFEYMKENLYQLMKDRNK-----LFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPEN-LLCMGPELVKIADFGLARELR-SQPPYTDYVSTRWYR 166          

HSP 2 Score: 37.3502 bits (85), Expect = 5.941e-18
Identity = 16/27 (59.26%), Postives = 22/27 (81.48%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APEVLL S+ YS+ +D+W+VG I AE+
Sbjct:  167 APEVLLRSSVYSSPIDVWAVGSIMAEL 193          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MPK15_ARATH (Mitogen-activated protein kinase 15 OS=Arabidopsis thaliana GN=MPK15 PE=2 SV=3)

HSP 1 Score: 72.4034 bits (176), Expect = 1.006e-17
Identity = 53/158 (33.54%), Postives = 77/158 (48.73%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +Y+  E VG+G+YG V  A D  TG+ VA+KK     D        LRE+ LL++L             H D     +   P S   F        ++Y+VFE +++DL + I ++        L P   Q FLYQL +G+ + H+  V HRDLKP+N
Sbjct:   89 RYQIQEVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLL------------HPDVVEIKHIMLPPSRREF-------RDVYVVFELMESDLHQVIKAN------DDLTPEHHQFFLYQLLRGLKYVHAANVFHRDLKPKN 221          

HSP 2 Score: 37.7354 bits (86), Expect = 1.006e-17
Identity = 26/61 (42.62%), Postives = 37/61 (60.66%), Query Frame = 1

Query:  511 FSRSPILASDAPSP-FLSKAIPTRLLLSGIGAPEVLLGS--THYSTAVDMWSVGCIFAEMV 684
            F  + +  +DAP+  F +  + TR       APE L GS  + Y+ A+D+WSVGCIFAEM+
Sbjct:  235 FGLARVSFNDAPTAIFWTDYVATRWYR----APE-LCGSFFSKYTPAIDIWSVGCIFAEML 290          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK15_RAT (Mitogen-activated protein kinase 15 OS=Rattus norvegicus GN=Mapk15 PE=1 SV=2)

HSP 1 Score: 65.4698 bits (158), Expect = 1.007e-17
Identity = 50/159 (31.45%), Postives = 75/159 (47.17%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            ++Y    ++G+G YG V+KA D+ TG++VA+KK      ++       RE+ LL+       ++RLL V      + + N                 ++YLVFE +DTDL   I   +KG   R L     +   YQL +     HS  V+HRD KP N
Sbjct:   12 QRYLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFGGHPNIIRLLDV------IPAKN---------------DRDIYLVFESMDTDLNAVI---QKG---RLLEDIHKRCIFYQLLRATKFIHSGRVIHRDQKPAN 143          

HSP 2 Score: 44.669 bits (104), Expect = 1.007e-17
Identity = 26/62 (41.94%), Postives = 34/62 (54.84%), Query Frame = 1

Query:  508 GFSRSPILASDAPSPFLSKAIPTRLLLSGIGAPEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            G +RS    SD P     +A+   +      APEVLL S  Y+  VDMWS+GCI  EM++ Q
Sbjct:  158 GLARS---LSDFPEGPGGQALTEYVATRWYRAPEVLLSSRWYTPGVDMWSLGCILGEMLRGQ 216          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: KSG4_ARATH (Shaggy-related protein kinase delta OS=Arabidopsis thaliana GN=ASK4 PE=2 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 1.013e-17
Identity = 43/152 (28.29%), Postives = 80/152 (52.63%), Query Frame = 3

Query:   33 VGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHS-HGVLHRDLKPQN 485
            VG G++G V++AK + TG++VA+KK   +   +       RE+ ++QML        ++C++H               S ++ + N +  L LV E++   + +   S+ +     PL    ++ + YQ+C+G+A+ H+  G+ HRD+KPQN
Sbjct:   88 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN------RELQIMQMLDHP----NVVCLKH---------------SFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPL--IYVKLYTYQICRGLAYLHNCCGLCHRDIKPQN 212          

HSP 2 Score: 44.669 bits (104), Expect = 1.013e-17
Identity = 16/31 (51.61%), Postives = 25/31 (80.65%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE++ G+T Y+TA+D+WS GC+ AE++  Q
Sbjct:  250 APELIFGATEYTTAIDIWSTGCVMAELLLGQ 280          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: HOG1_CANGA (Mitogen-activated protein kinase HOG1 OS=Candida glabrata GN=HOG1 PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 1.315e-17
Identity = 50/158 (31.65%), Postives = 70/158 (44.30%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +Y  L  VG G +G V  A D  T Q VA+KK         +     RE+ LL+ L        L+C++ +  S     P  D              +Y V E   TDL + + +       RPL    +Q F YQ+ +G+ + HS GV+HRDLKP N
Sbjct:   22 RYSDLNPVGMGAFGLVCSATDTLTNQQVAIKKIMKPFATAVLAKRTYRELKLLKHLRHE----NLICLQDIFLS-----PLED--------------IYFVTELQGTDLHRLLQT-------RPLEKQFVQYFHYQILRGLKYVHSAGVVHRDLKPSN 149          

HSP 2 Score: 40.4318 bits (93), Expect = 1.315e-17
Identity = 16/29 (55.17%), Postives = 21/29 (72.41%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVK 687
            APE++L    Y   VD+WS GCIFAEM++
Sbjct:  184 APEIMLTWQKYDVEVDIWSAGCIFAEMIE 212          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK06_CHICK (Mitogen-activated protein kinase 6 OS=Gallus gallus GN=MAPK6 PE=2 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 1.692e-17
Identity = 58/205 (28.29%), Postives = 90/205 (43.90%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHE------IVTLWYRGSR 608
            +Y  L+ +G G  G V+ A D    + VA+KK  L  D + +   ALRE+ +++ L            +++    +   PS    +    S    + +Y+V EY++TDL   ++         PL     + F+YQL +G+ + HS  VLHRDLKP N               GL R        Y+H+      +VT WYR  R
Sbjct:   19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAVKKIVLT-DPQSVKH-ALREIKIIRRLDH----------DNIVKVFEILGPSGSQLTDDVGSLTELNCVYIVQEYMETDLANLLEQG-------PLLEDHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMD---PHYSHKGHLSEGLVTKWYRSPR 201          

HSP 2 Score: 40.817 bits (94), Expect = 1.692e-17
Identity = 15/28 (53.57%), Postives = 22/28 (78.57%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            +P +LL   +Y+ A+DMW+ GCIFAEM+
Sbjct:  199 SPRLLLSPNNYTKAIDMWAAGCIFAEML 226          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: GSK3_DICDI (Glycogen synthase kinase-3 OS=Dictyostelium discoideum GN=gskA PE=1 SV=2)

HSP 1 Score: 64.3142 bits (155), Expect = 1.708e-17
Identity = 44/151 (29.14%), Postives = 77/151 (50.99%), Query Frame = 3

Query:   33 VGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +G G++G V +A    T ++VA+KK   +   +       RE+ +++ML+    V           SLK++         F TS+N +  L LV EY+   + +   S     + +P+P   ++ ++YQLC+ + + HS G+ HRD+KPQN
Sbjct:   62 IGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKN------RELQIMKMLNHINIV-----------SLKNS---------FYTSDNDEVYLNLVLEYVPDTVYRV--SRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQN 184          

HSP 2 Score: 45.0542 bits (105), Expect = 1.708e-17
Identity = 16/31 (51.61%), Postives = 26/31 (83.87%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE++ GST+Y+T +D+WS+GC+ AE++  Q
Sbjct:  222 APELIFGSTNYTTTIDVWSLGCVLAELLLGQ 252