CF417740

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: YIDC_SCHPO (Uncharacterized WD repeat-containing protein C227.12 OS=Schizosaccharomyces pombe GN=SPAC227.12 PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 2.423e-20
Identity = 58/222 (26.13%), Postives = 105/222 (47.30%), Query Frame = 3

Query:   33 PIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDW----------RNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIVKT 668
            PI  ++++  G++  +GS      VW+       Q F  H+     +DW             ++ AT + DN + + K  ++ P+    GH   V  V + P+G  L S S D T ++W++     +     HS+ I++I   P GS         +++S   D+  ++WD+  GK +  L+ H   + ++A+SPNG  LA+ S D ++ IW L++  +  T
Sbjct:  174 PIAIVRFSNNGNHFASGSWGGQVKVWNSDNLSEVQLFRGHTDRVSGLDWYPLCQAWDADSEQLTLATGAADNTVCLWKASQSTPLLRLEGHLARVGRVAFHPSGDYLVSASFDTTWRLWDVHTGVELLMQEGHSEGIFSIACQPDGS---------LVSSGGNDAIGRIWDLRSGKSIMVLDEHIRQIVAMAWSPNGYQLATSSADDTVKIWDLRKVSLAHT 386          

HSP 2 Score: 82.4185 bits (202), Expect = 2.347e-15
Identity = 56/209 (26.79%), Postives = 97/209 (46.41%), Query Frame = 3

Query:   15 LSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMI-YVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIW 638
            L  H   +  + ++  GDYL++ S D T  +WDV T       E HS     +  + + S  +S  ++ I  +  +   + I     H  ++  + W P G  LA+ S D T KIW++++    H +  HS  +  +R+    SG N       +A++ +D  VKLW+     L+ S+ GH E V S+     G+   S   D+++ +W
Sbjct:  261 LEGHLARVGRVAFHPSGDYLVSASFDTTWRLWDVHTGVELLMQEGHSEGIFSIACQPDGSLVSSGGNDAIGRIWDLRSGKSIMVLDEHIRQIVAMAWSPNGYQLATSSADDTVKIWDLRKVSLAHTIPAHSSLVSDVRY--IESGVNR-----FIATSGYDGCVKLWNPLNCSLIKSMVGHEEKVMSV--DGYGDRFISSGYDRTIKLW 460          

HSP 3 Score: 70.0922 bits (170), Expect = 1.205e-11
Identity = 39/128 (30.47%), Postives = 60/128 (46.88%), Query Frame = 3

Query:  270 GHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEG 653
            G +  +  V++   G+  AS S     K+WN      V   R H+  +  + W P     +  ++QL LA+ + D+TV LW       L  L GH   V  +AF P+G+YL S S D +  +W +  G
Sbjct:  170 GGERPIAIVRFSNNGNHFASGSWGGQVKVWNSDNLSEVQLFRGHTDRVSGLDWYPLCQAWDADSEQLTLATGAADNTVCLWKASQSTPLLRLEGHLARVGRVAFHPSGDYLVSASFDTTWRLWDVHTG 297          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: NLE1_PONAB (Notchless protein homolog 1 OS=Pongo abelii GN=NLE1 PE=2 SV=3)

HSP 1 Score: 98.9821 bits (245), Expect = 2.423e-20
Identity = 49/132 (37.12%), Postives = 74/132 (56.06%), Query Frame = 3

Query:  243 ENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIW 638
            + +P+    GHQ  +N V + P   ++AS S D + K+W+ +  KY+  LR H   +Y I WS             +L S S DST+K+WDV+  KL   L GH + VY++ +SP+G+ +ASG  DK + IW
Sbjct:  361 DKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR---------LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483          

HSP 2 Score: 80.4925 bits (197), Expect = 8.918e-15
Identity = 70/264 (26.52%), Postives = 105/264 (39.77%), Query Frame = 3

Query:   12 TLSKHKGPIFSLKW-----NKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKW---------------------DPTGSL---------------------LASCSDDVTAKIWNMKQDKY-VHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKI 659
            TL+ H   I  L W     N +  Y+ + S D +  +WD      ++    H+     + W  +    ++S D  I V +  +    +T  GH   VN +                       D  GSL                     L S SDD T  +W+  +DK  +  +  H   I  + +SP            I+ASASFD ++KLWD   GK L SL GH   VY +A+S +   L SGS D ++ +W +K  K+
Sbjct:  194 TLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLMRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSR---------IVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 448          

HSP 3 Score: 75.0998 bits (183), Expect = 3.747e-13
Identity = 54/202 (26.73%), Postives = 89/202 (44.06%), Query Frame = 3

Query:    6 KCT--LSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWR-NNVSFATSSTDNMIYVCKIGENRPI-KTFAGHQGEVNCVKWDPTGS-----LLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFS 584
            +CT  L  H   + S+ ++  G YL +GS D T   WD+ TE      + H    L + W  +    A+   +  I +      + + +T AGH   +  + W+P  +      +AS S D + +IW+    +    L  H++ +  +RW   G          +L SAS D T+K+W    G L  +L GH   V ++A S
Sbjct:  105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG----------LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALS 296          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: NLE1_HUMAN (Notchless protein homolog 1 OS=Homo sapiens GN=NLE1 PE=1 SV=3)

HSP 1 Score: 98.9821 bits (245), Expect = 2.423e-20
Identity = 49/132 (37.12%), Postives = 74/132 (56.06%), Query Frame = 3

Query:  243 ENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIW 638
            + +P+    GHQ  +N V + P   ++AS S D + K+W+ +  KY+  LR H   +Y I WS             +L S S DST+K+WDV+  KL   L GH + VY++ +SP+G+ +ASG  DK + IW
Sbjct:  361 DKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR---------LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483          

HSP 2 Score: 80.4925 bits (197), Expect = 8.918e-15
Identity = 70/264 (26.52%), Postives = 105/264 (39.77%), Query Frame = 3

Query:   12 TLSKHKGPIFSLKW-----NKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKW---------------------DPTGSL---------------------LASCSDDVTAKIWNMKQDKY-VHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKI 659
            TL+ H   I  L W     N +  Y+ + S D +  +WD      ++    H+     + W  +    ++S D  I V +  +    +T  GH   VN +                       D  GSL                     L S SDD T  +W+  +DK  +  +  H   I  + +SP            I+ASASFD ++KLWD   GK L SL GH   VY +A+S +   L SGS D ++ +W +K  K+
Sbjct:  194 TLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSR---------IVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 448          

HSP 3 Score: 75.0998 bits (183), Expect = 3.747e-13
Identity = 54/202 (26.73%), Postives = 89/202 (44.06%), Query Frame = 3

Query:    6 KCT--LSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWR-NNVSFATSSTDNMIYVCKIGENRPI-KTFAGHQGEVNCVKWDPTGS-----LLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFS 584
            +CT  L  H   + S+ ++  G YL +GS D T   WD+ TE      + H    L + W  +    A+   +  I +      + + +T AGH   +  + W+P  +      +AS S D + +IW+    +    L  H++ +  +RW   G          +L SAS D T+K+W    G L  +L GH   V ++A S
Sbjct:  105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG----------LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALS 296          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: YQ95_SCHPO (Uncharacterized WD repeat-containing protein C18.05c OS=Schizosaccharomyces pombe GN=SPCC18.05c PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 3.165e-20
Identity = 68/249 (27.31%), Postives = 115/249 (46.18%), Query Frame = 3

Query:   12 TLSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFH----------------SGPTLDVDWRNNVSFA---------------------TSSTDNMIYVCKIGEN--RPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWS 641
            TLS H  PI  ++W  + +++ + S DKT  +WD K  +     + H                SG     D++   SF+                      S++D++  +    +   +PI    GHQ  VN   + P G  +A+ S D + ++W+ K  K++  LR H   +Y   WS             +L S+S D+T+K+WDV   K+ + L GH + V+++ +SP+G+ +ASG  DK++ IWS
Sbjct:  264 TLSGHTAPITCVRWGGQ-NWIYSSSYDKTIRIWDAKDGKCLHILKGHAARVNHLSLSTEHVLRSGAYDHTDFKPK-SFSDERRKAKERYEACLKQSGERLVSASDDLQLILWDPQKSTKPITKMHGHQKVVNHASFSPDGRCIATASFDSSVRLWDGKTGKFLATLRGHVAAVYQCAWS---------TDSRLLVSSSQDTTLKVWDVRSKKMKFDLPGHEDQVFAVDWSPDGQRVASGGADKAVRIWS 501          

HSP 2 Score: 97.8265 bits (242), Expect = 5.398e-20
Identity = 67/221 (30.32%), Postives = 103/221 (46.61%), Query Frame = 3

Query:    6 KCTLSK--HKGPIFSLKWNKK-GDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHD-LREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGK 656
            +CT S   H G I S +++      L+TGS D TA +WD  T+                                          PI T  GH   V+CV W P  S++A+ S D T + W+ K+   + D LR H+K I  + W P     +  +   +LAS S D+TV++W+V+L  LL++L+GH  P+  + +     ++ S S DK++ IW  K+GK
Sbjct:  125 RCTASMNGHDGTIISAQFSPSTSSRLVTGSGDFTARLWDCDTQT-----------------------------------------PIATMKGHTNWVSCVAWAPDASIIATGSMDNTIRFWDPKKGSPIGDALRRHTKPIMALCWQPLHLAPD--SGPYLLASGSKDNTVRIWNVKLRTLLFTLSGHTAPITCVRWG-GQNWIYSSSYDKTIRIWDAKDGK 301          

HSP 3 Score: 91.6633 bits (226), Expect = 3.869e-18
Identity = 71/261 (27.20%), Postives = 105/261 (40.23%), Query Frame = 3

Query:   15 LSKHKGPIFSLKWNK------KGDYLL-TGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVN--------------------------------------CVKWDPTGSLLASCSDDVTAKIWN-MKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKI 659
            L +H  PI +L W         G YLL +GS D T  +W+VK          H+ P   V W       +SS D  I +    + + +    GH   VN                                      C+K   +G  L S SDD+   +W+  K  K +  +  H K +    +SP G           +A+ASFDS+V+LWD + GK L +L GH   VY  A+S +   L S S D ++ +W ++  K+
Sbjct:  216 LRRHTKPIMALCWQPLHLAPDSGPYLLASGSKDNTVRIWNVKLRTLLFTLSGHTAPITCVRWGGQNWIYSSSYDKTIRIWDAKDGKCLHILKGHAARVNHLSLSTEHVLRSGAYDHTDFKPKSFSDERRKAKERYEACLK--QSGERLVSASDDLQLILWDPQKSTKPITKMHGHQKVVNHASFSPDGR---------CIATASFDSSVRLWDGKTGKFLATLRGHVAAVYQCAWSTDSRLLVSSSQDTTLKVWDVRSKKM 465          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: WDR38_MOUSE (WD repeat-containing protein 38 OS=Mus musculus GN=Wdr38 PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 3.165e-20
Identity = 51/157 (32.48%), Postives = 84/157 (53.50%), Query Frame = 3

Query:  201 TSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIVKTY 671
            T+S D  +YV      R +   AGH+G V    + P G L+AS S D + ++W++ + K +H L+ H + + T+ +SP             LAS  +D    +W+V+ G+ ++ L GH + + S  FSP  + LA+GS D ++HIW L+    V +Y
Sbjct:   43 TASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSFSPDSKQ---------LASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVVSY 190          

HSP 2 Score: 90.1225 bits (222), Expect = 1.126e-17
Identity = 45/136 (33.09%), Postives = 73/136 (53.68%), Query Frame = 3

Query:  255 IKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIV 662
            ++ +  H GEVNC  + P G  L + SDD    +W  K  + +  L  H   + +  +SP G          ++AS+S D +++LWDV   K L+ L GH+  V +++FSP+ + LASG  DK   +W ++ G+ V
Sbjct:   19 VRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGR---------LIASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRV 145          

HSP 3 Score: 88.1965 bits (217), Expect = 4.277e-17
Identity = 60/222 (27.03%), Postives = 100/222 (45.05%), Query Frame = 3

Query:   15 LSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWR-NNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYV---HDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIVKT 668
            L+ H+GP+ S  ++  G  + + S D +  +WDV   +     + H      V +  ++   A+   D    V ++   R +    GH   +    + PT   LA+ S D T  IW+++    V   H+L  H+  I  + +S +G          +LAS S+D T+ +W      L   L GH   V SLAFSP+   LAS    +++ +W    GK ++T
Sbjct:   64 LAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVVSYHNLEGHTGNISCLCYSASG----------LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVKVWDCLTGKCLET 275          

HSP 4 Score: 86.6557 bits (213), Expect = 1.244e-16
Identity = 59/209 (28.23%), Postives = 104/209 (49.76%), Query Frame = 3

Query:    6 KC--TLSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWR-NNVSFATSSTDNMIYVCKIGENRPIKTF---AGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGS 614
            KC   L  H+  + ++ ++     L +G  DK AIVW+V++         H       D+   + S AT S D+ +++  +  + P+ ++    GH G ++C+ +  +G LLAS S D T  +W    +     L+ H+  + ++ +SP          +L LASA +  TVK+WD   GK L +L G  +  ++  F+P+G+ L SG+
Sbjct:  101 KCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVVSYHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSP---------DELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGA 299          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: NLE1_MOUSE (Notchless protein homolog 1 OS=Mus musculus GN=Nle1 PE=2 SV=3)

HSP 1 Score: 98.5969 bits (244), Expect = 3.165e-20
Identity = 49/132 (37.12%), Postives = 74/132 (56.06%), Query Frame = 3

Query:  243 ENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIW 638
            + +P+    GHQ  +N V + P   ++AS S D + K+W+ +  KY+  LR H   +Y I WS             +L S S DST+K+WDV+  KL   L GH + VY++ +SP+G+ +ASG  DK + IW
Sbjct:  361 DKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR---------LLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483          

HSP 2 Score: 80.8777 bits (198), Expect = 6.829e-15
Identity = 71/264 (26.89%), Postives = 105/264 (39.77%), Query Frame = 3

Query:   12 TLSKHKGPIFSLKW-----NKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKW---------------------DPTGSL---------------------LASCSDDVTAKIWNMKQDKY-VHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKI 659
            TL+ H   I  L W     N +  Y+ + S D +  VWD      ++    H+     + W  +    ++S D  I V +  +    +T  GH   VN +                       D  GSL                     L S SDD T  +W+  +DK  +  +  H   I  + +SP            I+ASASFD ++KLWD   GK L SL GH   VY +A+S +   L SGS D ++ +W +K  K+
Sbjct:  194 TLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSR---------IVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 448          

HSP 3 Score: 70.8626 bits (172), Expect = 7.066e-12
Identity = 52/202 (25.74%), Postives = 86/202 (42.57%), Query Frame = 3

Query:    6 KCT--LSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWR-NNVSFATSSTDNMIYVCKIGENRPI-KTFAGHQGEVNCVKWDPTG-----SLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFS 584
            +CT  L  H   + S+ ++  G YL +GS D T   WD+ TE      + H    L + W  +    A+   +  I +        + +T  GH   +  + W+P         +AS S D + ++W+    +    L  H++ +  +RW   G          +L SAS D T+K+W    G L  +L GH   V ++A S
Sbjct:  105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDG----------LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALS 296          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: CIAO1_ANOGA (Probable cytosolic iron-sulfur protein assembly protein Ciao1 OS=Anopheles gambiae GN=Ciao1 PE=3 SV=3)

HSP 1 Score: 98.5969 bits (244), Expect = 3.165e-20
Identity = 68/227 (29.96%), Postives = 114/227 (50.22%), Query Frame = 3

Query:   12 TLSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVK-TEEWKQQFEFHSGPTL---DVDWR---NNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNM-----KQDKY--VHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELG----KLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIW 638
            TL+ H G ++S  W+  G    +   DKT  VW+   T+ W  Q     G T    ++ W    + ++ A+  T   ++  K GE     T  GH  EV  V W  +G+LLA+CS D +  IW +     ++D+Y  V  L  H++++  + W P         Q+ +LASAS+D+T++++  +L     ++L  L  H   V+S++F   G+ LAS S D ++ +W
Sbjct:    9 TLTGHAGRVWSAAWHPGGKLFASCGEDKTIRVWNKSDTDRWVAQTVLTDGHTRTIRELAWSCCGHYLASASFDTTVAVWDKKSGEFECNATLEGHDNEVKSVTWSRSGNLLATCSRDKSVWIWEIHHAPDQEDEYECVAVLNGHTQDVKKVCWHP---------QEDLLASASYDNTIRMYRQDLADSEWEMLEPLESHSSTVWSISFDATGQRLASCSEDTTVKVW 226          

HSP 2 Score: 83.1889 bits (204), Expect = 1.376e-15
Identity = 51/142 (35.92%), Postives = 74/142 (52.11%), Query Frame = 3

Query:  237 IGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQ-DKYVHD---LREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKL--LYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSL 644
            +G+   ++T  GH G V    W P G L ASC +D T ++WN    D++V        H++ I  + WS  G           LASASFD+TV +WD + G+     +L GH   V S+ +S +G  LA+ S DKS+ IW +
Sbjct:    1 MGKLELLQTLTGHAGRVWSAAWHPGGKLFASCGEDKTIRVWNKSDTDRWVAQTVLTDGHTRTIRELAWSCCGH---------YLASASFDTTVAVWDKKSGEFECNATLEGHDNEVKSVTWSRSGNLLATCSRDKSVWIWEI 133          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: TUP11_SCHPO (Transcriptional repressor tup11 OS=Schizosaccharomyces pombe GN=tup11 PE=1 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 4.133e-20
Identity = 65/218 (29.82%), Postives = 110/218 (50.46%), Query Frame = 3

Query:    3 LKCTLSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYV--HDLREHS--KEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSL 644
            ++   S H+  I+SL ++  G ++++GS D+TA +WDV+T +   + E  +G T      N+   A  S D +I V  +     ++   GH+  V  + + P  S+L S S D T K+W ++  + V    ++     K  YT       S   +P+ +  L S S D +++ WD++ G+   +  GH+  V S+ FSP+G   ASGS D    IWS+
Sbjct:  394 VRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTL-VERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGL-SGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASGSGDLRARIWSI 609          

HSP 2 Score: 95.9005 bits (237), Expect = 2.051e-19
Identity = 69/224 (30.80%), Postives = 115/224 (51.34%), Query Frame = 3

Query:   21 KHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHS---GPTLDVDWRNNVSFA-------TSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIV 662
            +H   +  +K++  G YL TG C++ A V+DV+T   K+ F  H     P+ D+  R  ++F+       T + D  I +  +   +    F+GH+ ++  + +   G  + S S D TA++W+++  + +  L E    +  I  SP        N Q I A  S D  +++W V  G L+  L GH+E VYS+AFSP+   L SGSLDK++ +W L+  + V
Sbjct:  311 EHPSVVCCVKFSNNGKYLATG-CNQAANVFDVQTG--KKLFTLHEESPDPSRDLYVRT-IAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKL-EIENGVTAIAISP--------NDQFI-AVGSLDQIIRVWSVS-GTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRSV 519          

HSP 3 Score: 81.6481 bits (200), Expect = 4.003e-15
Identity = 58/218 (26.61%), Postives = 99/218 (45.41%), Query Frame = 3

Query:   42 SLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATS-STDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVEL------------GKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGK 656
            ++ ++  G YL+TG+ D+   +WD+ T++ +  F  H      +D+ +N  F  S S D    +  +   + I       G V  +   P    +A  S D   ++W++     V  L  H + +Y+I +SP  S         IL S S D T+K+W+++             G    +  GH + V S+A SP+  +  SGS D+SM  W L+ G+
Sbjct:  365 TIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENG-VTAIAISPNDQFIAVGSLDQIIRVWSVS-GTLVERLEGHKESVYSIAFSPDSS---------ILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQ 571          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: NLE1_BOVIN (Notchless protein homolog 1 OS=Bos taurus GN=NLE1 PE=2 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 4.133e-20
Identity = 49/132 (37.12%), Postives = 74/132 (56.06%), Query Frame = 3

Query:  243 ENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIW 638
            + +P+    GHQ  +N V + P   ++AS S D + K+W+ +  KY+  LR H   +Y I WS             +L S S DST+K+WDV+  KL   L GH + VY++ +SP+G+ +ASG  DK + IW
Sbjct:  361 DKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR---------LLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483          

HSP 2 Score: 79.7221 bits (195), Expect = 1.521e-14
Identity = 69/263 (26.24%), Postives = 105/263 (39.92%), Query Frame = 3

Query:   15 LSKHKGPIFSLKW-----NKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKW---------------------DPTGSL---------------------LASCSDDVTAKIWNMKQDKY-VHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKI 659
            L+ H   I +L W     N +  Y+ + S D +  VWD      ++    H+     + W  +    ++S D  I V +  +    +T  GH   VN +                       D  GSL                     L S SDD T  +W+  +DK  +  +  H   I  + +SP            ++ASASFD ++KLWD   GK L SL GH   VY +A+S +   L SGS D ++ +W +K  K+
Sbjct:  195 LTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNAQDLRGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSR---------VIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKL 448          

HSP 3 Score: 75.0998 bits (183), Expect = 3.747e-13
Identity = 60/224 (26.79%), Postives = 92/224 (41.07%), Query Frame = 3

Query:    6 KCT--LSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYV-HDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIVKT 668
            +CT  L  H   + S+ ++  G YL +GS D T   WD+ TE                                          P  T  GH+  V  + W P G  LAS   +    +W+    K V   L  HSK I  + W P  +   NP  + + AS+S D +V++WD   G+   +L GH + V  L +  +G  L S S D+++ +W   +G + +T
Sbjct:  105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTE-----------------------------------------TPHFTCQGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHA---NPECRYV-ASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRT 282          

HSP 4 Score: 68.1662 bits (165), Expect = 4.580e-11
Identity = 44/148 (29.73%), Postives = 68/148 (45.95%), Query Frame = 3

Query:  249 RPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLL-YSLNGHREPVYSLAF-----SPNGEYLASGSLDKSMHIWSLKEGKIVKTYT 674
            R   +  GH   V  V + PTG  LAS S D T + W++  +      + H   + +I WSP G           LAS   +  + LWD   GK +  +L GH + + +L++     +P   Y+AS S D S+ +W    G+  +T T
Sbjct:  105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGKK---------LASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLT 243          

BLAST of CF417740 vs. ExPASy Swiss-Prot
Match: LIS1_CAEEL (Lissencephaly-1 homolog OS=Caenorhabditis elegans GN=lis-1 PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 5.398e-20
Identity = 66/229 (28.82%), Postives = 105/229 (45.85%), Query Frame = 3

Query:    3 LKCTLSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDV-KTEEWKQQFEFHSGPTLDVDWRNNVSFATS-STDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQL------ILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIVK 665
            L+ TL  H   +  +  +  G  L++ S D +  +WD  +T +  +  + H      V +     F  S S D+ I    I     + TF GH   V  ++    G+L AS S D T  +W+         LR+H   +  + W+P  + TN   QQ       IL S S D ++K W++  G +L++L  H   V  LAF P G+YL S + DK++ +W L   + +K
Sbjct:  140 LERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMK 368          

HSP 2 Score: 82.4185 bits (202), Expect = 2.347e-15
Identity = 50/158 (31.65%), Postives = 77/158 (48.73%), Query Frame = 3

Query:  198 ATSSTDNMIYVCKIGENRPIKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQD-KYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSL--KEGKIV 662
            A+ S D  I V      +  +T  GH   VN +  D  G  L SCS D++ K+W+  Q    +  L+ H   + ++ + PTG           + SAS D T+K WD+  G  +Y+  GH + V  +  S +G   AS SLD+++ +WS   K  K+V
Sbjct:  122 ASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGD---------FVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLV 270          

HSP 3 Score: 74.3294 bits (181), Expect = 6.391e-13
Identity = 60/235 (25.53%), Postives = 102/235 (43.40%), Query Frame = 3

Query:   15 LSKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKTEEWKQQFEFHSGPTLDVDW-RNNVSFATSSTDNMIYVCKIGENRP-IKTFAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDVELGKLLYSLNGHREPVYSLAFSPNGEY---------------LASGSLDKSMHIWSLKEGKIVKT 668
            L+ H+ PI  + ++     + + S D T  VWD +T + ++  + H+    D+          + S+D  I +   G+    +K+  GH+  V+ V + PTG  + S S D T K W++     V+  R H+  +  IR S  G+         + ASAS D TV +W          L  H   V  + ++P+  Y               L SGS D+S+  W++  G ++ T
Sbjct:  102 LTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGT---------LFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFT 327          

HSP 4 Score: 72.7886 bits (177), Expect = 1.860e-12
Identity = 44/144 (30.56%), Postives = 70/144 (48.61%), Query Frame = 3

Query:  249 RPIKT--FAGHQGEVNCVKWDPTGSLLASCSDDVTAKIWNMKQDKYVHDLREHSKEIYTIRWSPTGSGTNNPNQQLILASASFDSTVKLWDV-ELGKLLYSLNGHREPVYSLAFSPNGEYLASGSLDKSMHIWSLKEGKIVKTY 671
            RP +T    GH+  +  V + P  +++ASCS+D T K+W+ +  +    L+ H+  +  I     G           L S S D ++KLWD  +    L SL GH   V S+ F P G+++ S S D ++  W +  G  V T+
Sbjct:   95 RPPETQKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQ---------LVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTF 229