CF832506

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP17A_CAVPO (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Cavia porcellus GN=CYP17A1 PE=1 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 1.193e-28
Identity = 67/184 (36.41%), Postives = 100/184 (54.35%), Query Frame = -2

Query:  170 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNF-----QYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKLNLSENFGIVIKKKEP 706
            W +A L+ +PQV KK+QEE+   VG            L  L+A ++E  R+ P  P+L+P +A+   SIG + I KDT +++N+WA+H + Q WD P +F PERFL        D +G+        YLPFG+G R C G  LA + +  + A LL  F+ E+P G +L   E    ++   +P
Sbjct:  313 WVIAFLLHNPQVKKKIQEEIDHNVGFSRTPTFSDRNHLLMLEATIREVLRIRPVAPILIPHKANTDSSIGEFAIDKDTNVLVNLWALHHNEQEWDRPDQFMPERFL--------DPTGSQIIVPSSSYLPFGAGPRSCVGEALARQEIFLITAWLLQKFDLEVPEGGQLPSLEGIPKIVFLIDP 488          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP17A_RANDY (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Rana dybowskii GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 3.470e-28
Identity = 68/178 (38.20%), Postives = 101/178 (56.74%), Query Frame = -2

Query:  176 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKL-NLSENFGIVIKKK 706
            W +A L+ +P+V KK+QEEL   VG            L Y +A + E  R+ P  PLL+P  A +  SIG YTIPK+  +++N+W++H D + W NP  F P+RFL+      +  S +   +LPFG+G R+C G  LA+  +   L+ +L  F  E+P G  L +L   FG+VI+ K
Sbjct:  326 WAVAYLLHYPEVQKKIQEELDVKVGFGRYPLLSDRKILHYTEAAISEVLRIRPVSPLLIPHVALKESSIGEYTIPKEARVVINLWSLHHDEKEWVNPHLFSPDRFLDENGNRVYSPSPS---FLPFGAGIRVCLGEALAKMEVFLFLSWILQRFTLEVPEGDPLPDLEGKFGVVIQVK 500          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP17A_PERLE (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Peromyscus leucopus GN=Cyp17a1 PE=3 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 3.470e-28
Identity = 62/164 (37.80%), Postives = 95/164 (57.93%), Query Frame = -2

Query:  215 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKL 706
            W +A L+ +P+V KK+Q+E+ Q +G            L  L+A ++E  R+ P  P+L+P +A+   SIG +TIPKDT +++N+WA+H + + WD P  F PERFL+         S     YLPFG+G R C G  LA ++L   +A LL  F+ ++P G  +
Sbjct:  311 WIVAFLLHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRIRPVAPMLIPHKANIDSSIGEFTIPKDTHVVINLWALHHNEKEWDQPDRFMPERFLDATGSHLITPS---LSYLPFGAGPRACIGEVLARQVLFLYVACLLQRFDLDVPDGAPM 471          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP17A_CHICK (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Gallus gallus GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 3.470e-28
Identity = 67/176 (38.07%), Postives = 98/176 (55.68%), Query Frame = -2

Query:  182 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKL-NLSENFGIVIK 706
            W +  L+ +P+V KK+QEE+ Q +G+         P L YL+A + E  R+ P  PLL+P  +    SIG Y+IPK   +++N+W++H D + WD P EF P RFL+   E        +  YLPFG+G R+C G  LA+  L   LA +L  F  E P    L +L   FG+V++
Sbjct:  316 WAVLYLLHYPEVQKKIQEEMDQKIGLARHPHLSDRPLLPYLEATISEGLRIRPVSPLLIPHVSLADTSIGEYSIPKGARVVINLWSVHHDEKEWDKPEEFNPGRFLD---EQGQHIHSPSPSYLPFGAGIRVCLGEVLAKMELFLFLAWVLQRFTLECPQDQPLPSLEGKFGVVLQ 488          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP2U1_BOVIN (Cytochrome P450 2U1 OS=Bos taurus GN=CYP2U1 PE=2 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 5.919e-28
Identity = 60/177 (33.90%), Postives = 99/177 (55.93%), Query Frame = -2

Query:  185 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNFQ---YLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKLNLSENFGIVI 706
            W +  +  HP + +K+ EE+A+V+G D         ++ Y +A + E  RL   +PL +P   SE   + G+TIPK T ++ N+W++HRDP +W+ P +F P+RFL        D  G   +   ++PFG G+R+C G  LA+  L  +  SL+ SF + LP  +K  L+  +G+ +
Sbjct:  363 WCLLYMSLHPNIQEKIHEEIARVIGADRAPSLTDKAQMPYTEATIMEVQRLSTVVPLSIPHMTSEKTVLQGFTIPKGTIILPNLWSVHRDPAIWEKPNDFYPDRFL--------DDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFVLPKDSKPILTGKYGLTL 531          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP17A_SQUAC (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Squalus acanthias GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.249e-27
Identity = 67/176 (38.07%), Postives = 98/176 (55.68%), Query Frame = -2

Query:  182 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKLNLSE-NFGIVIK 706
            W +  L+ HP+V KK+QEE+   +G +   +      + +L+A + E  R+ P  PLL+P  A    SIG YTIPK T +++N+WAIH D + W NP  F P RFL+   + K+  S +   YLPFG+G R+C G  LA   L    + +L  F  ++P G      E  FGIV++
Sbjct:  316 WMIIYLIHHPEVQKKIQEEIDSNIGFERTPKMSDKGNMNFLNATIHEILRIQPVSPLLIPHVALADSSIGDYTIPKGTRVIINLWAIHHDEKEWKNPDAFDPGRFLD--EDGKYVCSSSE-SYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQVPPGYPPPDKEGKFGIVLQ 488          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP17A_PANTR (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Pan troglodytes GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 2.938e-27
Identity = 65/174 (37.36%), Postives = 96/174 (55.17%), Query Frame = -2

Query:  185 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKLNLSENFGIVI 706
            WT+A L+ +PQV KK+ EE+ Q VG           +L  L+A ++E  RL P  P+L+P +A+   SIG + + K T +++N+WA+H + + W  P +F PERFLN         S     YLPFG+G R C G  LA + L  ++A LL  F+ E+P   +L   E    V+
Sbjct:  313 WTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTQVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPS---VSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVV 483          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: CP17A_HUMAN (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Homo sapiens GN=CYP17A1 PE=1 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 2.938e-27
Identity = 65/174 (37.36%), Postives = 96/174 (55.17%), Query Frame = -2

Query:  185 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFLNVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAGTKLNLSENFGIVI 706
            WT+A L+ +PQV KK+ EE+ Q VG           +L  L+A ++E  RL P  P+L+P +A+   SIG + + K T +++N+WA+H + + W  P +F PERFLN         S     YLPFG+G R C G  LA + L  ++A LL  F+ E+P   +L   E    V+
Sbjct:  313 WTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPS---VSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVV 483          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: C71AS_ARATH (Putative cytochrome P450 71A28 OS=Arabidopsis thaliana GN=CYP71A28 PE=3 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 2.938e-27
Identity = 70/189 (37.04%), Postives = 103/189 (54.50%), Query Frame = -2

Query:  152 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLW-DNPLEFRPERFLNVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWEL---PAGTKLNLSENFGIVIKKKEPLIAIPT 706
            W M  +++HP+ MKK+QEE+         V E  +  +KYL AV+KE FRLHP  PL +PR+ SE              + +N WAIHRD + W     EF+PER L++      ++ G +F ++PFGSGRR+C  I  A  ++   LA+ ++ F W +   P G    L +  G+ +  K PLIA P+
Sbjct:  312 WAMTLVVRHPESMKKLQEEIQTYSRNKLYVPEEEVENMKYLKAVIKEVFRLHPPGPLSIPRQLSED-------------VFINAWAIHRDTEKWGPYAEEFKPERHLDL----PLNFQGQDFNFIPFGSGRRLCPDIDFATMLIEVGLANFVYRFNWRVETRPLGDDDGLKQT-GMEVCHKFPLIAFPS 482          

BLAST of CF832506 vs. ExPASy Swiss-Prot
Match: C79F2_ARATH (Hexahomomethionine N-hydroxylase OS=Arabidopsis thaliana GN=CYP79F2 PE=1 SV=2)

HSP 1 Score: 121.709 bits (304), Expect = 3.837e-27
Identity = 66/196 (33.67%), Postives = 112/196 (57.14%), Query Frame = -2

Query:  125 WTMAELMQHPQVMKKVQEELAQVVGMDSCVEEFHLPKLKYLDAVVKETFRLHPALPLLVPRRASESGSIGGYTIPKDTTLMLNVWAIHRDPQLWDNPLEFRPERFL-NVGVESKFDYSGNNFQYLPFGSGRRMCAGIPLAERMLMFVLASLLHSFEWELPAG-TKLNLSENFGIVIKKKEPLIAIPTPRLSNSELY 706
            WT+ E++++P++++K  +EL +VVG D  V+E  +  L YL A  +ETFR+HP+   + P  A +  ++GGY IPK + + +    + R+P++W +PL + PER L   G+  +        +++ F +GRR C G+ +   M+  +LA  L  F W+L      L+L E+   ++  K PL+    PRL+ S LY
Sbjct:  339 WTLGEMLKNPEILRKALKELDEVVGKDRLVQESDIRNLNYLKACCRETFRIHPSAHYVPPHVARQDTTLGGYFIPKGSHIHVCRPGLGRNPKIWKDPLAYEPERHLQGDGITKEVTLVETEMRFVSFSTGRRGCVGVKVGTIMMAMMLARFLQGFNWKLHRDFGPLSLEEDDASLLMAK-PLLLSVEPRLA-SNLY 532