CF835261

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP51_MYCTU (Lanosterol 14-alpha demethylase OS=Mycobacterium tuberculosis GN=cyp51 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.500e-12
Identity = 51/193 (26.42%), Postives = 87/193 (45.08%), Query Frame = 1

Query:   85 SEDTIIGLLWDMITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTETDFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHFAW---APPEGVKPEEIDM 654
            S D I G+   M+ AG  T++ +  W + EL+++        +ELD + G  R ++      +P L+ V KE LRLHPP  ++L   A    ++ G+ + +G  +  +     R P  + DP             +   + +  +PFGAGR  C GA   I  + ++   LL  + +    PPE  + +   M
Sbjct:  242 SADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLRLHPPL-IILMRVAKGEFEVQGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKM 433          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP51_MYCBO (Lanosterol 14-alpha demethylase OS=Mycobacterium bovis GN=cyp51 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.500e-12
Identity = 51/193 (26.42%), Postives = 87/193 (45.08%), Query Frame = 1

Query:   85 SEDTIIGLLWDMITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTETDFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHFAW---APPEGVKPEEIDM 654
            S D I G+   M+ AG  T++ +  W + EL+++        +ELD + G  R ++      +P L+ V KE LRLHPP  ++L   A    ++ G+ + +G  +  +     R P  + DP             +   + +  +PFGAGR  C GA   I  + ++   LL  + +    PPE  + +   M
Sbjct:  242 SADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLRLHPPL-IILMRVAKGEFEVQGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKM 433          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP4F1_RAT (Cytochrome P450 4F1 OS=Rattus norvegicus GN=Cyp4f1 PE=2 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.500e-12
Identity = 54/211 (25.59%), Postives = 94/211 (44.55%), Query Frame = 1

Query:   10 LARRAVVPTHYFVDALLTLQEK--YDLSEDTIIGLLWDMITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTET---DFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHFAWAPPE 627
            L  +A   T  F+D LL  +++   +LS++ I       +  G DTTA    W +  L  +P  Q++ ++E+  ++  +R   E    D + LP+L    KE+LRLHPP  ++        +   G  +PKG    ++++ +  +P+VW DP           ++         +PF AG R C G    ++ +   L   L  F   P +
Sbjct:  287 LKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLANDPEYQERCRQEVQELLR-DRDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDPEVYNPFRFDPENI-KDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDD 495          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP3AV_MESAU (Cytochrome P450 3A31 OS=Mesocricetus auratus GN=CYP3A31 PE=2 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.500e-12
Identity = 60/202 (29.70%), Postives = 91/202 (45.05%), Query Frame = 1

Query:   46 VDALLTLQEKYDLSEDT--------IIGLLWDMITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTETDFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKG--HDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHFAWAP 621
            VD L  +   +D S+D+        II      I AG DTT+ +  + +  L  +P VQ+K QEE+D  +  +   +      + YL  V  E LRL+ P    L      +V++ G  VPKGS + V V+A+  DP  W +P             + KG    +  LPFG G R C G +  +  +   L  +L +F+  P
Sbjct:  268 VDFLQLMMNSHDNSKDSHKALSDMEIIAQSIIFIFAGYDTTSSTLSFALYLLATHPDVQKKLQEEIDIALPNKARPSYDKVMEMEYLDMVLNETLRLY-PIGSRLERVCKQDVEMDGVFVPKGSIVMVPVFALHYDPQYWPEP---EKFRPERFSKENKGSIDPYIFLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSLQP 465          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP11A_BOVIN (Cholesterol side-chain cleavage enzyme, mitochondrial OS=Bos taurus GN=CYP11A1 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.500e-12
Identity = 50/169 (29.59%), Postives = 86/169 (50.89%), Query Frame = 1

Query:  115 DMITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTETDFSNL----PYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHF 609
            +M+  G++TT+++ +W + E+ ++  VQ+  +EE+       R   E D S +    P L+A  KE LRLHP + + L     +++ +  Y +P  + + V ++A+ RDPA +  P           D D+    FR L FG G R C G ++    +T  L H+L +F
Sbjct:  321 EMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNA----RRQAEGDISKMLQMVPLLKASIKETLRLHPIS-VTLQRYPESDLVLQDYLIPAKTLVQVAIYAMGRDPAFFSSPDKFDPTRWLSKDKDLI--HFRNLGFGWGVRQCVGRRIAELEMTLFLIHILENF 482          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP3AI_RAT (Cytochrome P450 3A18 OS=Rattus norvegicus GN=Cyp3a18 PE=2 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 4.571e-12
Identity = 52/172 (30.23%), Postives = 84/172 (48.84%), Query Frame = 1

Query:  121 ITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTETDFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKG--HDFRLLPFGAGRRVCPGAQLG-INLVTSMLGHLLHHFAWAPPE 627
            I  G D T+ S  + M EL   P VQ+K Q E+DR +  +  +T      + YL  V  E+LRL+ P    L   +  +V+I G  +PKG+ + + ++ + R+P  W +P             + KG    +  LPFG G R C G +   I++  +++G +L +F   P E
Sbjct:  303 IFGGYDATSTSISFIMYELATRPNVQKKLQNEIDRALPNKAPVTYDALMEMEYLDMVVNESLRLY-PIATRLDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYWLEP---EEFNPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVIG-VLQNFNIQPCE 469          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP3A7_HUMAN (Cytochrome P450 3A7 OS=Homo sapiens GN=CYP3A7 PE=1 SV=2)

HSP 1 Score: 71.633 bits (174), Expect = 4.571e-12
Identity = 49/167 (29.34%), Postives = 78/167 (46.71%), Query Frame = 1

Query:  121 ITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTETDFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHFAWAP 621
            I AG +TT+    + + EL  +P VQQK Q+E+D V+  +   T      L YL  V  E LRL  P  + L      +V+I G  +PKG  + +  + +  DP  W++P           + D     +   PFG+G R C G +  +  +   L  +L +F++ P
Sbjct:  303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLF-PVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWREPEKFLPERFSKKNKD-NIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKP 467          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: C85A1_ORYSJ (Cytochrome P450 85A1 OS=Oryza sativa subsp. japonica GN=CYP85A1 PE=1 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 4.571e-12
Identity = 52/195 (26.67%), Postives = 98/195 (50.26%), Query Frame = 1

Query:   46 VDALLTLQE--KYDLSEDTIIGLLWDMITAGMDTTAISTEWGMAELIKNPR-VQQKAQEELDRVIGF--ERVMTETDFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHFAW 615
            +DALLT  E  +  L+++ II L+  +I +G +T + ++   +  L  +P+ ++Q  +E  D   G   E  +   DF ++ + +AV  E LRL      +L  +   +V++ GY +PKG  I+V    +  DP ++ DP+          +++   H    + FG G R+CPG ++G   + + L + +  + W
Sbjct:  252 LDALLTGVEGTREKLTDEQIIDLIITLIYSGYETMSTTSMMAVKYLSDHPKALEQLRKEHFDIRKGKAPEDAIDWNDFKSMTFTRAVIFETLRLATVVNGLL-RKTTQDVEMNGYVIPKGWRIYVYTREINYDPFLYPDPMTFNPWRWLEKNMESHPH---FMLFGGGSRMCPGKEVGTVEIATFLHYFVTQYRW 442          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP4C3_DROME (Cytochrome P450 4c3 OS=Drosophila melanogaster GN=Cyp4c3 PE=2 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 5.970e-12
Identity = 52/178 (29.21%), Postives = 85/178 (47.75%), Query Frame = 1

Query:   43 FVDALLTL-QEKYDLSEDTIIGLLWDMITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTET--DFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGI 567
            F+D L+   +E   LS + I   +   +  G DTT+ +  W +  L  +P  Q++  EELD + G ++    T  +  ++ YL+   K++LRL P  P M+      +V IGG  VP G+   +  +A+ R+P V+  P           +   + H F  +PF AG R C G +  I
Sbjct:  313 FLDLLIDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVP-MMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGR-HPFAYIPFSAGPRNCIGQKFAI 488          

BLAST of CF835261 vs. ExPASy Swiss-Prot
Match: CP3A9_RAT (Cytochrome P450 3A9 OS=Rattus norvegicus GN=Cyp3a9 PE=2 SV=2)

HSP 1 Score: 71.2478 bits (173), Expect = 5.970e-12
Identity = 49/180 (27.22%), Postives = 85/180 (47.22%), Query Frame = 1

Query:   82 LSEDTIIGLLWDMITAGMDTTAISTEWGMAELIKNPRVQQKAQEELDRVIGFERVMTETDFSNLPYLQAVAKEALRLHPPTPLMLPHRANANVKIGGYDVPKGSNIHVNVWAVARDPAVWKDPLXXXXXXXXXXDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMLGHLLHHFAWAP 621
            LS+  I+      I AG +TT+ +  + +  L  +P +Q+K Q+E+D  +  +   T      + YL  V  E LRL+P     L      +V+I G  +PKG+ + +  +A+ +DP  W +P           + D   + +  LPFG G R C G +  +  +   L  +L +F++ P
Sbjct:  290 LSDVEIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAG-RLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQD-NINPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSFQP 467