CK934111

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: DHB12_BOVIN (Estradiol 17-beta-dehydrogenase 12 OS=Bos taurus GN=HSD17B12 PE=2 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 7.140e-13
Identity = 63/244 (25.82%), Postives = 113/244 (46.31%), Query Frame = 3

Query:   63 GMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNKGFKVTGS--VCDLSSREQREKLIETVTSIFQGKLNILVNNAAIVFVKPTLDITAEDMST----VSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMIK---PFEEGPAGSEFLDGIARQTPIGRAGEPDEVSSLVAFLCLPAASYI 767
            G  A+VTGGT GIG +  EELA+ G  +   SR+Q +LD    E   K FKV       D +S +  +K+  ++  +    + +LVNN  + +  P   +   D+      + + N  SV  +++L  P       G+I+ ISS  G+  +P +++Y A K  ++  ++ L  E+    +   +V P+ + T + K   P  + P+   F+    +   +        + SLVA +     S++
Sbjct:   50 GEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLDQVSSEISEK-FKVETKTIAVDFTSEDIYDKIKASLAGL---NIGVLVNNVGMSYEYPEYFLDVPDLDNTIKKLITVNALSVCKMTRLVLPGMVERSKGAILNISSASGMYPVPLLTIYSATKAFVDFFSQCLHEEYKSKGVIVQSVLPYYVATKLAKIKRPTWDKPSPETFVKSAMKTIGVQSRTNGYPIHSLVASVSASLPSWL 289          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: DH12A_DANRE (Estradiol 17-beta-dehydrogenase 12-A OS=Danio rerio GN=hsd17b12a PE=2 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 7.140e-13
Identity = 60/196 (30.61%), Postives = 99/196 (50.51%), Query Frame = 3

Query:   63 GMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELD--ARLHEWKNKGFKVTGSVCDLSSREQREKLIETVTSIFQGKLNILVNNAAIVFVKPTLDITAEDM----STVSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMIK 632
            G  A+VTG T GIG +  EELAR G  +   SR+Q +LD  A+  E   K    T +V D S  +   K+ + +  +   ++ ILVNN  I +  P   +   D+    +T+ + N  SV  +++L  P  +A   G I+ ISS  G+  +P +++Y + K  ++  ++ L  E+    I   +V P+ + T M K
Sbjct:   56 GKWAVVTGATDGIGKSYAEELARRGFSMMLISRSQEKLDDVAKSLESTYKVETKTIAV-DFSQIDVYPKIEKGLAGL---EIGILVNNVGISYSYPEFFLHIPDLENFITTMINVNITSVCQMTRLVLPRMEARAKGVILNISSASGMFPVPLLTIYSSTKAFVDFFSRGLQTEYKCKGIIIQSVLPFFVATKMTK 247          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: DHB12_ANAPL (Estradiol 17-beta-dehydrogenase 12 OS=Anas platyrhynchos GN=HSD17B12 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 9.325e-13
Identity = 58/196 (29.59%), Postives = 94/196 (47.96%), Query Frame = 3

Query:   63 GMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNK-GFKVTGSVCDLSSREQREKLIETVTSIFQG-KLNILVNNAAIVFVKPTLDITAEDMST----VSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMIK 632
            G  A+VTG T GIG A  +ELA+ G  V   SR++ +LD    E   + G +    V D     +RE + + + +  +G ++ +LVNN  I +  P   I   D+      + + N  SV  +++L  P       G I+ ISS  G+   P ++LY A K  ++  ++ L  E+    I   +V P+ + T M K
Sbjct:   48 GAWAVVTGATDGIGKAYAKELAKRGMKVALISRSKEKLDQVAGEITEQYGVETKVIVADFG---EREDIYDRIRAGLEGLEIGVLVNNVGISYSYPEYFIDVPDLDKTIDKMININIMSVCKMTRLVLPGMLERSKGVILNISSAAGMYPTPLLTLYSASKAFVDYFSRGLHAEYKSKGIIVQSVMPYYVATKMSK 240          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: BEND_ACIAD (1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase OS=Acinetobacter sp. (strain ADP1) GN=benD PE=3 SV=2)

HSP 1 Score: 74.3294 bits (181), Expect = 9.325e-13
Identity = 67/247 (27.13%), Postives = 111/247 (44.94%), Query Frame = 3

Query:   75 LVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNKGFKVTGSVCDLSSREQREKLIETVTSIFQGKLNILVNNAA-IVFVKPTLDITAEDMSTVSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMIK-PFEEGPAGS-------EFLDGIARQTPIGRAGEPDEVSSLVAFLCLPAASYITGQIICV 788
            +VTG  +GIG      +A+ G  +    R+ + + A L E K  G        DL +    E ++    + + G++++L+NN    +++KP  + + E++      +        +   P       G+IV +SS+   RGI  +  Y A KG +N LT +LA E A+  IR N VA    K    K P    P          + +D    ++ +GR G  DE  + + FL    +SYITG ++ V
Sbjct:   13 IVTGAAQGIGRGVALRIAQEGGCLILADRSDL-IQAVLAEIKALGALAIAVETDLETYAGAELVVSHAIAEY-GRIDVLINNVGGAIWMKPFQEFSEEEIIQEVHRSLFPALWCCRAVLPEMLKHQQGTIVNVSSIA-TRGIHRIP-YSASKGGVNALTASLAFEHAQHGIRVNAVATGGTKAPPRKIPRNAQPLSKSEQVWMQQVVDQTIDRSFLGRYGSIDEQVNAITFLASDESSYITGSVLPV 255          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: YM71_YEAST (Uncharacterized oxidoreductase YMR226C OS=Saccharomyces cerevisiae GN=YMR226C PE=1 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.218e-12
Identity = 57/190 (30.00%), Postives = 95/190 (50.00%), Query Frame = 3

Query:   69 TALVTGGTRGIGHATVEEL--ARFGAIVHTCSRNQIELDARLHEWKNKGF---KVTGSVCDLSSREQREKLIETVTSIFQGKLNILVNNAAIVFVKPTL-DITAEDMSTVSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKT 620
            T L+TG + GIG AT  E   A  G +    +  ++E    L +  ++ F   KV  +  D++  E+ +  IE +   F+  ++ILVNNA        +  I  ED+  V  TN  ++ +++Q   P+F+A  +G IV + S+ G    P+ S+Y A K A+   T +L  E     IR   +AP +++T
Sbjct:   15 TVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKD-IDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRVILIAPGLVET 203          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: DHRS1_HUMAN (Dehydrogenase/reductase SDR family member 1 OS=Homo sapiens GN=DHRS1 PE=1 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.218e-12
Identity = 55/199 (27.64%), Postives = 91/199 (45.73%), Query Frame = 3

Query:   57 LNGMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNKGFKVTGSVCDLSSREQREKLIETVTSIFQGKLNILVNNAAI-------VFVKPTLDITAEDMSTVSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMIK 632
            +NG   +VTG +RGIG     +L + GA V+   R+   L     E ++ G +    VCD S   +   L E V    QG+L++LVNNA            K   +  A     +++      +  S     L   +G G IV ISS G ++ + +V  YG  K A ++L  + A E  +  +   ++ P +++T ++K
Sbjct:    5 MNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVP-YGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLK 202          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: DH12B_XENLA (Estradiol 17-beta-dehydrogenase 12-B OS=Xenopus laevis GN=hsd17b12-B PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.218e-12
Identity = 53/194 (27.32%), Postives = 89/194 (45.88%), Query Frame = 3

Query:   63 GMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNKGFKVTGSVCDLSSREQREKLIETVTSIFQGKLNILVNNAAIVFVKPTLDITAEDMST----VSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMIK 632
            G  A+VTG T GIG A  EELAR G  +   SR+  +L+      K K FKV   +      +  E        +   ++ +LVNN  I +  P   +   D+      + + N  SV  +++L  P     G G ++ ISS  G+  +P +++Y A K  ++  ++ L  E+    +   +V P+ + T + K
Sbjct:   54 GKWAVVTGATDGIGKAYAEELARRGMNIVLISRSPEKLEEAAIHIKQK-FKVETKIIAADFGKPTEIYERIEAGLRDLEIGVLVNNVGISYEYPEYFLEIPDLENTLDKMININIMSVCQMTRLVLPGMLGRGKGVVLNISSASGMYPVPLLTVYSATKAFVDFFSRGLHAEYRSKGVTVQSVLPFFVATKLAK 246          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: XYLL_PSEPU (1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase OS=Pseudomonas putida GN=xylL PE=3 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 1.591e-12
Identity = 72/249 (28.92%), Postives = 117/249 (46.99%), Query Frame = 3

Query:   63 GMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNK---GFKVTGSVCDLSSREQREKLIETVTSIFQGKLNILVNN-AAIVFVKPTLDITAEDM-STVSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKT------SMIKPFEEGPAG-SEFLDGIARQTPIGRAGEPDEVSSLVAFLCLPAASYITG 773
            G  A++TG  +GIG    E +A  G  +    R+++     +HE  ++     +V     DL    + ++++      F G+L+IL+NN    ++ KP       ++ + V  + F +++       P+ +  G+G+IV +SSV   RGI  V  YGA KG +N LT  LA E A+  IR N  AP   +       +  +P E+      + +D     + + R G  DE    + FL   AASYITG
Sbjct:    7 GKVAVITGAAQGIGRRVAERMAAEGGRLLLVDRSEL-----IHELADELVGVAEVLTLTADLEQFAECQRVMAAALERF-GRLDILINNVGGTIWAKPFEHYQEREIEAEVRRSLFPTLWCCHAALAPMIE-QGSGAIVNVSSV-ATRGIHRVP-YGAAKGGVNALTACLAFETAERGIRVNATAPGGTEARHGGFRNSAEPSEQEKVWYQQIVDQSLDSSLMKRYGSIDEQVEAILFLASDAASYITG 246          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: HSDL1_CHICK (Hydroxysteroid dehydrogenase-like protein 1 OS=Gallus gallus GN=HSDL1 PE=2 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 2.077e-12
Identity = 55/207 (26.57%), Postives = 99/207 (47.83%), Query Frame = 3

Query:   15 MGEQELISRSKRWSLNGMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNKGFKVTGSVCDLSSREQREKLIETVTSIFQGKLNILVNNAAIVFVKPTL--DITAEDMSTVSSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMI 629
            +GE +++ R  RW      A+VTG T GIG A  EELA+ G  +   SR++ +L+A +    ++ +KV          + RE        +   ++ ILVNN  + +  P    +++ + +  + + N  S   +  +  P       G+IV +SS    +  P ++ YGA K  ++  ++ L  E+A   I   ++ P+VI T M+
Sbjct:   57 VGEIDIVKRYGRW------AVVTGSTDGIGKAYAEELAKRGVNIILISRSKEKLEA-VSRSISETYKVETDFIVADFSKGREAYQAIKEGLKDREIGILVNNVGLFYTYPDYFTNLSEDMLWDMINVNIASANMMVHIVLPGMVEKRKGAIVNVSSASCCQPTPMLTTYGASKAYLDYFSRALYYEYASKGIFVQSLTPFVIATRMV 256          

BLAST of CK934111 vs. ExPASy Swiss-Prot
Match: DHB12_MACFA (Estradiol 17-beta-dehydrogenase 12 OS=Macaca fascicularis GN=HSD17B12 PE=2 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 2.077e-12
Identity = 62/196 (31.63%), Postives = 99/196 (50.51%), Query Frame = 3

Query:   63 GMTALVTGGTRGIGHATVEELARFGAIVHTCSRNQIELDARLHEWKNKGFKV-TGSVC-DLSSREQREKLIETVTSIFQGKLNILVNNAAIVFVKPTLDITAEDMSTV----SSTNFESVFHLSQLAHPLFKASGNGSIVFISSVGGVRGIPSVSLYGAYKGAMNQLTKNLACEWAKDNIRTNTVAPWVIKTSMIK 632
            G  A+VTGGT GIG +  EELA+ G  V   SR+Q +LD    E K K FKV T ++  D +  +  +K+    T +   ++ ILVNN  + +  P   +   D+  V     + N  SV  ++QL  P       G+I+ ISS  G+  +P +++Y A K  ++  ++ L  E+    I   +V P+ + T + K
Sbjct:   50 GEWAVVTGGTDGIGKSYAEELAKRGMKVVLISRSQDKLDQVSSEIKEK-FKVETRTIAVDFTLEDIYDKI---KTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMFPVPLLTIYSATKTFVDFFSQCLHEEYRSKGIFVQSVLPYFVATKLAK 241