CK934114

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SIK2_PONAB (Serine/threonine-protein kinase SIK2 OS=Pongo abelii GN=SIK2 PE=2 SV=1)

HSP 1 Score: 206.453 bits (524), Expect = 1.928e-52
Identity = 110/246 (44.72%), Postives = 157/246 (63.82%), Query Frame = 2

Query:  206 RVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKR--ILDPN 937
            RVG Y++  TLG+G+FA VK  ++  T   VAIKI+D+ Q L    +E+I RE+  MK++ HP++IK+ +VM +K+ +Y+V E+   GE+FD +A HGRL E EARR   Q+++AVDYCH R + HRDLK ENLLLD+   +KI+DF   +     +   LL T  G+P Y APEV   + Y+G   D+WS GV+L+VL+ G LPFD   L  L +++    F  P   S   + LI+R  +LDP+
Sbjct:   16 RVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADF---SFGNFFKSGELLATWRGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPS 257          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: AAPK1_CAEEL (5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Caenorhabditis elegans GN=aak-1 PE=2 SV=2)

HSP 1 Score: 205.297 bits (521), Expect = 4.296e-52
Identity = 99/241 (41.08%), Postives = 156/241 (64.73%), Query Frame = 2

Query:  206 RVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            ++G + +  T+G+G+F  VK   +++TG  VAIKI++R ++     V + + EI  ++ + HP++ ++  V+++ + I++V+E + GGELF  I + G L   E+RRY QQ+I+ V YCH+  + HRDLKPENLLLD+   +KI+DFGL   S  + +  LL TACG+PNY APE++++K Y G   D+WSCGVIL+ ++ G LPFD+ N+  L+ KI    ++ P      A  LI  +L
Sbjct:   20 KIGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGL---SNYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTML 257          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: GIN4_YEAST (Serine/threonine-protein kinase GIN4 OS=Saccharomyces cerevisiae GN=GIN4 PE=1 SV=1)

HSP 1 Score: 204.527 bits (519), Expect = 7.327e-52
Identity = 112/266 (42.11%), Postives = 162/266 (60.90%), Query Frame = 2

Query:  188 VPASRTR-VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDR--------------DQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDE--SNLMALYRKICRADFSCP--XXFSSGAKKLIKRIL 928
            +PA +   +G ++LG TLG GS  KV+  +N  TG   A+K++ +                     +   I+REI  MKL+ HPNV+++ +V  + T +Y+VLE+ + GELF+ + + G L E EA R+ +Q+I  V YCH+ G+ HRDLKPENLLLD    +KI+DFG++A+     E  LL T+CG+P+Y APE+++   Y G ASDVWSCGVILF L+ G LPFDE   N+  L  K+ + +F  P     S  A+ LI++IL
Sbjct:    8 IPAIKDNTIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALE---TEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKIL 270          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: KCC4_YEAST (Probable serine/threonine-protein kinase KCC4 OS=Saccharomyces cerevisiae GN=KCC4 PE=1 SV=3)

HSP 1 Score: 203.756 bits (517), Expect = 1.250e-51
Identity = 114/272 (41.91%), Postives = 164/272 (60.29%), Query Frame = 2

Query:  161 AEVEKMSVKVPASRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDR------------DQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDE--SNLMALYRKICRADFSCP--XXFSSGAKKLIKRIL 928
            A  E  S   P+S   +G ++LG TLG GS  KV+  ++  TG   A+K++ +            D VL +     I+REI  MKL+ HPNV+ + +V  +   +Y++LE+ + GELF+ +  HG L E EA    +Q+I  + YCH+ G+ HRDLKPENLLLDS+  +KI+DFG++A+     +  LL T+CG+P+Y APE+++   Y+G ASDVWSCGVILF L+ G LPFDE   N+  L  K+ +  F  P     S  A+ LI +IL
Sbjct:    4 ANTETHSAAKPSST--IGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYN----IEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQ---TDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKIL 266          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: MRKC_DICDI (Probable serine/threonine-protein kinase MARK-C OS=Dictyostelium discoideum GN=mrkC PE=3 SV=1)

HSP 1 Score: 202.601 bits (514), Expect = 2.784e-51
Identity = 102/246 (41.46%), Postives = 158/246 (64.23%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTK---IYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRILDPN 937
            VG YE+G+TLG G+F KVK   N+ T + VAIK +  ++ L  K  E   REI  MKL+ HPN++K+++V+  + +    Y+++E++ GGELFD I     +KE EAR++ +Q+I+A++YCH+  + HRDLKPENLLLDS G +KISDFGL   S  ++   LL + CG+P Y APE+L  + Y G   D+WS GVI++ ++ G LP++  +   +       ++  P   S+ A  +++R++ PN
Sbjct:   43 VGSYEVGKTLGNGTFGKVKLGTNICTKENVAIKFIKNNK-LSGKQKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFDYIVAREYIKEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGDIKISDFGL---SNNIQPGKLLESFCGSPLYAAPEILKAEKYLGPPVDIWSLGVIMYAVLCGNLPWEGDSQAEISFNSVHGNYEDPTHLSAEAVHILRRMIVPN 284          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: AAPK1_PIG (5'-AMP-activated protein kinase catalytic subunit alpha-1 (Fragments) OS=Sus scrofa GN=PRKAA1 PE=1 SV=2)

HSP 1 Score: 197.978 bits (502), Expect = 6.858e-50
Identity = 100/243 (41.15%), Postives = 146/243 (60.08%), Query Frame = 2

Query:  200 RTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            R ++G Y LG TLG G+F K                                +REI  +KL +HP++IK+ +V+++ + I++V+E++ GGELFD I K+GRL E E+RR  QQ+++ VDYCH   V HRDLKPEN+LLD++   KI+DFGL   S  + +   L T+CG+PNY APEV++ + Y G   D+WS GVIL+ L+ G LPFD+ ++  L++KIC   F  P   +     L+K +L
Sbjct:    3 RVKIGHYILGDTLGVGTFGK--------------------------------RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHML 210          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: MRKA_DICDI (Probable serine/threonine-protein kinase MARK-A OS=Dictyostelium discoideum GN=mrkA PE=3 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 1.995e-49
Identity = 100/246 (40.65%), Postives = 157/246 (63.82%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVET-GDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL--DPN 937
            +G Y + +T+G G F KVK   + +   + VAIKI+++ + L  + ++ ++RE+  MKL+ HPN+I++ EV+ +   +Y+++E+   GE+ D +  HG L E +AR +  Q+++A++YCHS+   HRDLKPENLLLD    +KI DFGLS +         L T CG+P Y +PE++  K Y+G + DVWS GV+LFVL+ G LPFD  N + L++KI   +++ P   +   K LI R+L  DP+
Sbjct:  106 IGNYLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGK-LDPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNV---FTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLPFDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPD 347          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SNRK_RAT (SNF-related serine/threonine-protein kinase OS=Rattus norvegicus GN=Snrk PE=1 SV=1)

HSP 1 Score: 194.126 bits (492), Expect = 9.903e-49
Identity = 101/241 (41.91%), Postives = 155/241 (64.32%), Query Frame = 2

Query:  212 GKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGR-LKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLL-DSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            G Y+L +TLG G FA VK  ++V TG+ VA+K++D+ + L       + +E+  MKL++HPN++++ EV+ ++TK+Y++LE  DGG++FD I KH   L ED A++Y  Q+++A+ YCH   V HRDLKPEN++  +  G++K++DFG S   Q  ++   L T+CG+  Y APE+L    YD  A D+WS GVILF+L+ G  PF E+N       I    ++ P   S+G + LI R+L
Sbjct:   14 GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRML 250          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SNRK_MOUSE (SNF-related serine/threonine-protein kinase OS=Mus musculus GN=Snrk PE=1 SV=1)

HSP 1 Score: 194.126 bits (492), Expect = 9.903e-49
Identity = 101/241 (41.91%), Postives = 155/241 (64.32%), Query Frame = 2

Query:  212 GKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGR-LKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLL-DSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            G Y+L +TLG G FA VK  ++V TG+ VA+K++D+ + L       + +E+  MKL++HPN++++ EV+ ++TK+Y++LE  DGG++FD I KH   L ED A++Y  Q+++A+ YCH   V HRDLKPEN++  +  G++K++DFG S   Q  ++   L T+CG+  Y APE+L    YD  A D+WS GVILF+L+ G  PF E+N       I    ++ P   S+G + LI R+L
Sbjct:   14 GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRML 250          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SNRK_HUMAN (SNF-related serine/threonine-protein kinase OS=Homo sapiens GN=SNRK PE=1 SV=2)

HSP 1 Score: 191.815 bits (486), Expect = 4.915e-48
Identity = 101/241 (41.91%), Postives = 153/241 (63.49%), Query Frame = 2

Query:  212 GKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGR-LKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLL-DSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            G Y+L +TLG G FA VK  ++V TG+ VA+K++D+ + L       + +E+  MKL++HPN++++ EV+ ++TK+Y++LE  DGG++FD I KH   L ED A++Y  Q+++A+ YCH   V HRDLKPEN++  +  G++K++DFG S   Q  ++   L T+CG+  Y APE+L    YD  A D+WS GVILF+L+ G  PF E+N       I    ++ P   S   K LI R+L
Sbjct:   14 GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRML 250