CK934114

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: AAPK2_RAT (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Rattus norvegicus GN=Prkaa2 PE=1 SV=1)

HSP 1 Score: 232.646 bits (592), Expect = 2.513e-60
Identity = 113/243 (46.50%), Postives = 165/243 (67.90%), Query Frame = 2

Query:  200 RTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            R ++G Y LG TLG G+F KVK  ++  TG  VA+KI++R ++    +V +IKREI  +KL +HP++IK+ +V+++ T  ++V+E++ GGELFD I KHGR++E EARR  QQ+++AVDYCH   V HRDLKPEN+LLD+    KI+DFGL   S  + +   L T+CG+PNY APEV++ + Y G   D+WSCGVIL+ L+ G LPFD+ ++  L++KI    F  P   +     L+  +L
Sbjct:   10 RVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHML 249          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: AAPK1_RAT (5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Rattus norvegicus GN=Prkaa1 PE=1 SV=2)

HSP 1 Score: 232.646 bits (592), Expect = 2.513e-60
Identity = 116/257 (45.14%), Postives = 171/257 (66.54%), Query Frame = 2

Query:  158 TAEVEKMSVKVPASRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            TAE +K        R ++G Y LG TLG G+F KVK  K+  TG  VA+KI++R ++    +V +I+REI  +KL +HP++IK+ +V+++ + I++V+E++ GGELFD I K+GRL E E+RR  QQ+++ VDYCH   V HRDLKPEN+LLD++   KI+DFGL   S  + +   L T+CG+PNY APEV++ + Y G   D+WS GVIL+ L+ G LPFD+ ++  L++KIC   F  P   +     L+K +L
Sbjct:   12 TAEKQKHD-----GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHML 260          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: AAPK1_MOUSE (5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Mus musculus GN=Prkaa1 PE=1 SV=2)

HSP 1 Score: 232.646 bits (592), Expect = 2.513e-60
Identity = 116/257 (45.14%), Postives = 171/257 (66.54%), Query Frame = 2

Query:  158 TAEVEKMSVKVPASRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            TAE +K        R ++G Y LG TLG G+F KVK  K+  TG  VA+KI++R ++    +V +I+REI  +KL +HP++IK+ +V+++ + I++V+E++ GGELFD I K+GRL E E+RR  QQ+++ VDYCH   V HRDLKPEN+LLD++   KI+DFGL   S  + +   L T+CG+PNY APEV++ + Y G   D+WS GVIL+ L+ G LPFD+ ++  L++KIC   F  P   +     L+K +L
Sbjct:   12 TAEKQKHD-----GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHML 260          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: AAPK1_HUMAN (5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4)

HSP 1 Score: 232.646 bits (592), Expect = 2.513e-60
Identity = 116/257 (45.14%), Postives = 171/257 (66.54%), Query Frame = 2

Query:  158 TAEVEKMSVKVPASRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            TAE +K        R ++G Y LG TLG G+F KVK  K+  TG  VA+KI++R ++    +V +I+REI  +KL +HP++IK+ +V+++ + I++V+E++ GGELFD I K+GRL E E+RR  QQ+++ VDYCH   V HRDLKPEN+LLD++   KI+DFGL   S  + +   L T+CG+PNY APEV++ + Y G   D+WS GVIL+ L+ G LPFD+ ++  L++KIC   F  P   +     L+K +L
Sbjct:   12 TAEKQKHD-----GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHML 260          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SNF1_YEAST (Carbon catabolite-derepressing protein kinase OS=Saccharomyces cerevisiae GN=SNF1 PE=1 SV=1)

HSP 1 Score: 230.72 bits (587), Expect = 9.548e-60
Identity = 115/248 (46.37%), Postives = 169/248 (68.15%), Query Frame = 2

Query:  194 ASRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRILDPN 937
            A    +G Y++ +TLGEGSF KVK   +  TG  VA+KI+++  + +  M  +I+REIS ++L++HP++IK+ +V+ SK +I +V+E+  G ELFD I +  ++ E EARR+ QQ+I+AV+YCH   + HRDLKPENLLLD +  +KI+DFGLS I   + +   L T+CG+PNY APEV++ K Y G   DVWSCGVIL+V++   LPFD+ ++  L++ I    ++ P   S GA  LIKR+L  N
Sbjct:   47 ADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVN 290          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: BRSK1_MOUSE (BR serine/threonine-protein kinase 1 OS=Mus musculus GN=Brsk1 PE=2 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 3.071e-58
Identity = 109/247 (44.13%), Postives = 165/247 (66.80%), Query Frame = 2

Query:  191 PASRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRILD 931
            P     VG Y L +TLG+G    VK   +  TG  VA+KIV+R++ L   ++ +++REI+ +KLI+HP+V+K+ +V  +K  +Y+VLE + GGELFD + K GRL   EAR++ +Q+++A+D+CHS  + HRDLKPENLLLD    ++I+DFG++++      D LL T+CG+P+Y  PEV+  + YDGR +D+WSCGVILF L+ G LPFD+ NL  L  K+ R  F  P       + L++ +++
Sbjct:   25 PQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREK-LSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIE 267          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: BRSK1_HUMAN (BR serine/threonine-protein kinase 1 OS=Homo sapiens GN=BRSK1 PE=1 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 3.071e-58
Identity = 109/241 (45.23%), Postives = 164/241 (68.05%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRILD 931
            VG Y L +TLG+G    VK   +  TG  VAIKIV+R++ L   ++ +++REI+ +KLI+HP+V+K+ +V  +K  +Y+VLE + GGELFD + K GRL   EAR++ +Q+++A+D+CHS  + HRDLKPENLLLD    ++I+DFG++++      D LL T+CG+P+Y  PEV+  + YDGR +D+WSCGVILF L+ G LPFD+ NL  L  K+ R  F  P       + L++ +++
Sbjct:   47 VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIE 283          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: AAPK2_CAEEL (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Caenorhabditis elegans GN=aak-2 PE=1 SV=2)

HSP 1 Score: 225.328 bits (573), Expect = 4.011e-58
Identity = 112/244 (45.90%), Postives = 162/244 (66.39%), Query Frame = 2

Query:  197 SRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            ++ ++G Y L  TLG G+F KVK   +  T   VA+KI++R ++    +V +I+REI  + L +HP++I++ +V+++ + I++++E + GGELFD I KHGRLK  EARR+ QQ+I+ VDYCH   V HRDLKPENLLLD    +KI+DFGLS I   + +   L T+CG+PNY APEV++ K Y G   DVWSCGVIL+ L+ G LPFD+ ++ +L+RKI    F  P         L+  +L
Sbjct:   80 AQIKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNI---MTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHML 320          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SNF1_SCHPO (SNF1-like protein kinase ssp2 OS=Schizosaccharomyces pombe GN=ssp2 PE=1 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 5.239e-58
Identity = 111/244 (45.49%), Postives = 164/244 (67.21%), Query Frame = 2

Query:  197 SRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            S+  +G Y +  TLGEGSF KVK   + +T   VA+K + R  + +  M  +++REIS +KL++HP++IK+ +V+ + T I +V+E+  GGELFD I +  R+ EDE RR+ QQ+I A++YCH   + HRDLKPENLLLD    +KI+DFGLS I   + +   L T+CG+PNY APEV+N K Y G   DVWSCG++L+V++ G LPFD+  +  L++K+    +  P   S GA+ LI+R++
Sbjct:   27 SKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMI 266          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: BRSK2_HUMAN (BR serine/threonine-protein kinase 2 OS=Homo sapiens GN=BRSK2 PE=1 SV=3)

HSP 1 Score: 224.942 bits (572), Expect = 5.239e-58
Identity = 110/241 (45.64%), Postives = 163/241 (67.63%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRILD 931
            VG Y L +TLG+G    VK   +  T   VAIKIV+R++ L   ++ +++REI+ +KLI+HP+V+K+ +V  +K  +Y+VLE + GGELFD + K GRL   EAR++ +Q+I+A+D+CHS  + HRDLKPENLLLD    ++I+DFG++++      D LL T+CG+P+Y  PEV+  + YDGR +DVWSCGVILF L+ G LPFD+ NL  L  K+ R  F  P       + L++ +++
Sbjct:   16 VGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIE 252