CK934114

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: MARK4_HUMAN (MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 1.685e-56
Identity = 106/246 (43.09%), Postives = 158/246 (64.23%), Query Frame = 2

Query:  191 PASRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            P  +  VG Y L RT+G+G+FAKVK  +++ TG  VAIKI+D+ Q L    ++++ RE+  MK + HPN++K+ EV+ ++  +Y+V+E+   GE+FD +  HGR+KE EAR   +Q+++AV YCH + + HRDLK ENLLLD+   +KI+DFG    S +      L T CG+P Y APE+   K YDG   D+WS GVIL+ L++G LPFD  NL  L  ++ R  +  P   S+  + +++R L
Sbjct:   50 PEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFG---FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFL 291          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: PAR1_CAEBR (Serine/threonine-protein kinase par-1 OS=Caenorhabditis briggsae GN=par-1 PE=3 SV=1)

HSP 1 Score: 219.55 bits (558), Expect = 2.201e-56
Identity = 110/240 (45.83%), Postives = 157/240 (65.42%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            VGKY+L +T+G+G+FAKVK  K+V TG  VAIKI+D+   L    ++++ RE+  MK + HPN++K+ +VM ++  +Y+VLE+  GGE+FD +  HGR+KE EAR   +Q+++AV Y HS+ + HRDLK ENLLLD    +KI+DFG    S        L T CG+P Y APE+ + K YDG   DVWS GVIL+ L++G LPFD  NL  L  ++ R  +  P   S+  + L+K+ L
Sbjct:  125 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKT-ALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFG---FSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 360          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: MARK2_RAT (Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus GN=Mark2 PE=1 SV=1)

HSP 1 Score: 219.55 bits (558), Expect = 2.201e-56
Identity = 105/240 (43.75%), Postives = 158/240 (65.83%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            +G Y L +T+G+G+FAKVK  +++ TG  VA+KI+D+ Q L    ++++ RE+  MK++ HPN++K+ EV+ ++  +Y+V+E+  GGE+FD +  HGR+KE EAR   +Q+++AV YCH + + HRDLK ENLLLD+   +KI+DFG    S +      L T CG+P Y APE+   K YDG   DVWS GVIL+ L++G LPFD  NL  L  ++ R  +  P   S+  + L+K+ L
Sbjct:   50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: MARK2_HUMAN (Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2)

HSP 1 Score: 219.55 bits (558), Expect = 2.201e-56
Identity = 105/240 (43.75%), Postives = 158/240 (65.83%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            +G Y L +T+G+G+FAKVK  +++ TG  VA+KI+D+ Q L    ++++ RE+  MK++ HPN++K+ EV+ ++  +Y+V+E+  GGE+FD +  HGR+KE EAR   +Q+++AV YCH + + HRDLK ENLLLD+   +KI+DFG    S +      L T CG+P Y APE+   K YDG   DVWS GVIL+ L++G LPFD  NL  L  ++ R  +  P   S+  + L+K+ L
Sbjct:   50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: MARK2_MOUSE (Serine/threonine-protein kinase MARK2 OS=Mus musculus GN=Mark2 PE=1 SV=3)

HSP 1 Score: 216.468 bits (550), Expect = 1.863e-55
Identity = 104/240 (43.33%), Postives = 157/240 (65.42%), Query Frame = 2

Query:  209 VGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            +G Y L +T+G+G+FAKVK  +++ TG  VA+KI+D+ Q L    ++++ RE+  MK++ HPN++K+ EV+ ++  +Y+V+E+  GGE+FD +  HGR+KE EAR   +Q+++AV YCH + + HRDLK ENLLLD+   +KI+DFG    S +      L T CG+P Y APE+   K  DG   DVWS GVIL+ L++G LPFD  NL  L  ++ R  +  P   S+  + L+K+ L
Sbjct:   50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKIDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SIK2_MOUSE (Serine/threonine-protein kinase SIK2 OS=Mus musculus GN=Sik2 PE=1 SV=1)

HSP 1 Score: 214.157 bits (544), Expect = 9.248e-55
Identity = 113/246 (45.93%), Postives = 158/246 (64.23%), Query Frame = 2

Query:  206 RVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKR--ILDPN 937
            RVG Y++  TLG+G+FA VK  ++  T   VAIKI+D+ Q L    +E+I RE+  MK++ HP++IK+ +VM +K+ +Y+V E+   GE+FD +A HGRL E EARR   Q+++AVDYCH R V HRDLK ENLLLD+   +KI+DFG        +   LL T CG+P Y APEV   + Y+G   D+WS GV+L+VL+ G LPFD   L  L +++    F  P   S   + LI+R  +LDP+
Sbjct:   16 RVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNF---FKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPS 257          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SIK3_MOUSE (Serine/threonine-protein kinase SIK3 OS=Mus musculus GN=Sik3 PE=1 SV=3)

HSP 1 Score: 213.772 bits (543), Expect = 1.208e-54
Identity = 110/246 (44.72%), Postives = 159/246 (64.63%), Query Frame = 2

Query:  206 RVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKR--ILDPN 937
            R+G YE+ RT+G+G+FA VK   ++ T   VAIKI+D+ Q L  + +++I RE+  MK++ HP++I++ +VM ++  IY+V E+  GGE+FD +  HGR+ E EARR  +Q++ AV +CH R + HRDLK ENLLLD+   +KI+DFG S +        LL T CG+P Y APE+   K YDG   D+WS GV+L+VL+ G LPFD S L  L  ++    F  P   S+  + LI+   +LDPN
Sbjct:    4 RIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQ-LDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNL---FTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPN 245          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: HSL1_YEAST (Probable serine/threonine-protein kinase HSL1 OS=Saccharomyces cerevisiae GN=HSL1 PE=1 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 1.208e-54
Identity = 116/280 (41.43%), Postives = 164/280 (58.57%), Query Frame = 2

Query:  197 SRTRVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRH-------------KMVEQ----------------------IKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYG-VLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKRIL 928
            SR  VG ++LG+TLG+GS  +V+  KN+ETG   AIKIV + +   H              MV                        I+REI  MKLI H NV+ + EV  +K+++Y+VLE++DGGELFD +   G+L E EA  Y +Q++  V YCHS  + HRDLKPENLLLD     +KI+DFG++A+      + LL T+CG+P+Y +PE++  + Y G  SDVWSCG++LF L+ G LPF++ N+  L  K+    +  P   SS A+ LI +IL
Sbjct:   74 SRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALE---LPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKIL 350          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SIK3_HUMAN (Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3)

HSP 1 Score: 213.386 bits (542), Expect = 1.577e-54
Identity = 110/246 (44.72%), Postives = 159/246 (64.63%), Query Frame = 2

Query:  206 RVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKR--ILDPN 937
            R+G YE+ RT+G+G+FA VK   ++ T   VAIKI+D+ Q L  + +++I RE+  MK++ HP++I++ +VM ++  IY+V E+  GGE+FD +  HGR+ E EARR  +Q++ AV +CH R + HRDLK ENLLLD+   +KI+DFG S +        LL T CG+P Y APE+   K YDG   D+WS GV+L+VL+ G LPFD S L  L  ++    F  P   S+  + LI+   +LDPN
Sbjct:    4 RIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQ-LDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNL---FTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPN 245          

BLAST of CK934114 vs. ExPASy Swiss-Prot
Match: SIK2_HUMAN (Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 1.577e-54
Identity = 112/246 (45.53%), Postives = 158/246 (64.23%), Query Frame = 2

Query:  206 RVGKYELGRTLGEGSFAKVKFTKNVETGDFVAIKIVDRDQVLRHKMVEQIKREISTMKLIKHPNVIKIIEVMASKTKIYIVLEFIDGGELFDKIAKHGRLKEDEARRYLQQLINAVDYCHSRGVFHRDLKPENLLLDSYGVLKISDFGLSAISQQVREDGLLHTACGTPNYVAPEVLNDKGYDGRASDVWSCGVILFVLMAGVLPFDESNLMALYRKICRADFSCPXXFSSGAKKLIKR--ILDPN 937
            RVG Y++  TLG+G+FA VK  ++  T   VAIKI+D+ Q L    +E+I RE+  MK++ HP++IK+ +VM +K+ +Y+V E+   GE+FD +A HGRL E EARR   Q+++AVDYCH R + HRDLK ENLLLD+   +KI+DFG        +   LL T CG+P Y APEV   + Y+G   D+WS GV+L+VL+ G LPFD   L  L +++    F  P   S   + LI+R  +LDP+
Sbjct:   16 RVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNF---FKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPS 257