CK934154

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: MLTK_MOUSE (Mitogen-activated protein kinase kinase kinase MLT OS=Mus musculus GN=Mltk PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 59/185 (31.89%), Postives = 91/185 (49.19%), Query Frame = 3

Query:  219 GEGGFGCVYKAK-LDDNLHVAVKKLDCATQDAGREFENEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            G G FG VY+AK +  +  VAVKKL         + E E ++LS + H N++   G         IV E     SL   ++  +    +     M  A D A+G+ YLH      VIHRDLKS N+++ +    K+ DFG   +    +  ++ L GT  ++APE +    +++  D Y++GVVL
Sbjct:   23 GGGSFGSVYRAKWISQDKEVAVKKL--------LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINS-NRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFG--ASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVL 196          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: M3K13_PONAB (Mitogen-activated protein kinase kinase kinase 13 OS=Pongo abelii GN=MAP3K13 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 64/209 (30.62%), Postives = 102/209 (48.80%), Query Frame = 3

Query:  165 EYKLLEKAT-----DSFHESNILGEGGFGCVYKAKLDDNLHVAVKKLDCATQDAGREFENEVDL--LSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            +YKL ++ T     +   E   LG G  G V+  K      VA+KK+        RE +NE D+  L  + HPN++   G         I+ E   +  L   L     G  +T  + +  +   A G+ YLH H    +IHRDLKS N+L+      K+SDFG +  + S     +  +GT+ ++APE + +  +++K D+++FGVVL
Sbjct:  152 DYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE-EVAIKKV--------RE-QNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRA---GRKITPRLLVDWSTGIASGMNYLHLH---KIIHRDLKSPNVLVTHTDAVKISDFGTS-KELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVL 343          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: M3K13_MOUSE (Mitogen-activated protein kinase kinase kinase 13 OS=Mus musculus GN=Map3k13 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 64/209 (30.62%), Postives = 102/209 (48.80%), Query Frame = 3

Query:  165 EYKLLEKAT-----DSFHESNILGEGGFGCVYKAKLDDNLHVAVKKLDCATQDAGREFENEVDL--LSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            +YKL ++ T     +   E   LG G  G V+  K      VA+KK+        RE +NE D+  L  + HPN++   G         I+ E   +  L   L     G  +T  + +  +   A G+ YLH H    +IHRDLKS N+L+      K+SDFG +  + S     +  +GT+ ++APE + +  +++K D+++FGVVL
Sbjct:  151 DYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE-EVAIKKV--------RE-QNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRA---GRKITPRLLVDWSTGIASGMNYLHLH---KIIHRDLKSPNVLVTHTDAVKISDFGTS-KELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVL 342          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: M3K13_HUMAN (Mitogen-activated protein kinase kinase kinase 13 OS=Homo sapiens GN=MAP3K13 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 64/209 (30.62%), Postives = 102/209 (48.80%), Query Frame = 3

Query:  165 EYKLLEKAT-----DSFHESNILGEGGFGCVYKAKLDDNLHVAVKKLDCATQDAGREFENEVDL--LSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            +YKL ++ T     +   E   LG G  G V+  K      VA+KK+        RE +NE D+  L  + HPN++   G         I+ E   +  L   L     G  +T  + +  +   A G+ YLH H    +IHRDLKS N+L+      K+SDFG +  + S     +  +GT+ ++APE + +  +++K D+++FGVVL
Sbjct:  152 DYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE-EVAIKKV--------RE-QNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRA---GRKITPRLLVDWSTGIASGMNYLHLH---KIIHRDLKSPNVLVTHTDAVKISDFGTS-KELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVL 343          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: M3K13_BOVIN (Mitogen-activated protein kinase kinase kinase 13 OS=Bos taurus GN=MAP3K13 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 64/209 (30.62%), Postives = 102/209 (48.80%), Query Frame = 3

Query:  165 EYKLLEKAT-----DSFHESNILGEGGFGCVYKAKLDDNLHVAVKKLDCATQDAGREFENEVDL--LSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            +YKL ++ T     +   E   LG G  G V+  K      VA+KK+        RE +NE D+  L  + HPN++   G         I+ E   +  L   L     G  +T  + +  +   A G+ YLH H    +IHRDLKS N+L+      K+SDFG +  + S     +  +GT+ ++APE + +  +++K D+++FGVVL
Sbjct:  152 DYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE-EVAIKKV--------RE-QNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRA---GRKITPRLLVDWSTGIASGMNYLHLH---KIIHRDLKSPNVLVTHTDAVKISDFGTS-KELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVL 343          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: FER_RAT (Proto-oncogene tyrosine-protein kinase Fer (Fragment) OS=Rattus norvegicus GN=Fer PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 62/190 (32.63%), Postives = 96/190 (50.53%), Query Frame = 3

Query:  213 ILGEGGFGCVYKAKLDDNLHVAVKKL-DCATQDAGREFENEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLH-EHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITD--GSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            +LG+G FG VYK  L D   VAVK   +   Q+   +F  E  +L    HPN+V L+G        +I+ EL+     D           L     ++ +LD A G+ YL  ++C    IHRDL + N L+      K+SDFG++  +  G  + + LK    + + APE L  G+ + +SDV++FG++L
Sbjct:   69 LLGKGNFGEVYKGTLKDKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGG--DFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNC----IHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSGLK-QIPIKWTAPEALNYGRYSSESDVWSFGILL 251          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: FER_MOUSE (Proto-oncogene tyrosine-protein kinase Fer OS=Mus musculus GN=Fer PE=1 SV=2)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 61/190 (32.11%), Postives = 96/190 (50.53%), Query Frame = 3

Query:  213 ILGEGGFGCVYKAKLDDNLHVAVKKL-DCATQDAGREFENEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLH-EHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITD--GSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            +LG+G FG VYK  L D   VA+K   +   Q+   +F  E  +L    HPN+V L+G        +I+ EL+     D           L     ++ +LD A G+ YL  ++C    IHRDL + N L+      K+SDFG++  +  G  + + LK    + + APE L  G+ + +SDV++FG++L
Sbjct:  569 LLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGG--DFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNC----IHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSGLK-QIPIKWTAPEALNYGRYSSESDVWSFGILL 751          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: EPHB1_RAT (Ephrin type-B receptor 1 OS=Rattus norvegicus GN=Ephb1 PE=2 SV=2)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 62/196 (31.63%), Postives = 97/196 (49.49%), Query Frame = 3

Query:  213 ILGEGGFGCVYKAKLD----DNLHVAVKKLDCA-TQDAGREFENEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLA---ITDGSQNKNNLKLSGTL--GYVAPEYLLDGKLTDKSDVYAFGVVL 770
            ++G G FG VYK +L       ++VA+K L    ++   R+F +E  ++    HPN++ L G         I+ E MEN +LD  L    +    T    + +    A G++YL E      +HRDL + NIL++S    K+SDFGL+     D S       L G +   + APE +   K T  SDV+++G+V+
Sbjct:  624 VIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR--QNDGQFTVIQLVGMLRGIAAGMKYLSE---MNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVM 814          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: EPHB1_MOUSE (Ephrin type-B receptor 1 OS=Mus musculus GN=Ephb1 PE=2 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 62/196 (31.63%), Postives = 97/196 (49.49%), Query Frame = 3

Query:  213 ILGEGGFGCVYKAKLD----DNLHVAVKKLDCA-TQDAGREFENEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLA---ITDGSQNKNNLKLSGTL--GYVAPEYLLDGKLTDKSDVYAFGVVL 770
            ++G G FG VYK +L       ++VA+K L    ++   R+F +E  ++    HPN++ L G         I+ E MEN +LD  L    +    T    + +    A G++YL E      +HRDL + NIL++S    K+SDFGL+     D S       L G +   + APE +   K T  SDV+++G+V+
Sbjct:  624 VIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR--QNDGQFTVIQLVGMLRGIAAGMKYLSE---MNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVM 814          

BLAST of CK934154 vs. ExPASy Swiss-Prot
Match: DLK1_CAEBR (Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis briggsae GN=dlk-1 PE=3 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.342e-15
Identity = 60/193 (31.09%), Postives = 92/193 (47.67%), Query Frame = 3

Query:  192 DSFHESNILGEGGFGCVYKAKLDDNLHVAVKKLDCATQDAGREFENEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVVL 770
            D+      LG G  G V+  + + N  VAVKK++          E E+  L ++ H N++  LG  +      IV E      L   L      + +T  M      + A G+ YLH++    VIHRDLKS NIL+ ++ + K+ DFG +      +   +   GT+ ++APE +      +K DVY+FGVVL
Sbjct:   60 DAISNLEWLGSGSQGAVFHGQYE-NRTVAVKKVNQLK-------ETEIKHLRHLRHKNIIEFLGVCSKSPCYCIVMEYCPKGQLCTVLR---QKNLITRQMFSDWVKEIADGMHYLHQN---KVIHRDLKSPNILISAEDSIKICDFGTSHLQKKNDSTMMSFCGTVSWMAPEMIKKEPCNEKVDVYSFGVVL 238