CK934495

BLAST of CK934495 vs. ExPASy Swiss-Prot
Match: 2AAA_MOUSE (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Mus musculus GN=Ppp2r1a PE=1 SV=3)

HSP 1 Score: 267.314 bits (682), Expect = 6.461e-71
Identity = 133/223 (59.64%), Postives = 173/223 (77.58%), Query Frame = 1

Query:    4 TIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVRFFATQAL 672
            TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI  LSQSLLPAIVELAED  WRVRLAIIEY+PLLA QLGV FFD+KL +LCM WL D VY+IR+AA +N+K+L E+FG +WA   I+P+VL M  +P+YL+RMT L  I++L+ V G +IT   +LP V+  + D V N++FNVAK LQ + PI+D S ++  ++P L +L++D DVDV++FA +AL
Sbjct:  361 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL 583          

HSP 2 Score: 93.9745 bits (232), Expect = 9.790e-19
Identity = 56/217 (25.81%), Postives = 104/217 (47.93%), Query Frame = 1

Query:   13 QLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDW----AMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVR 651
            +++P+F +L  DE   VRL  +     + Q++  + L   ++P + + AED+ WRVR  + +    L   +G       L       +KD    +R AA++ VK   E    D      M  I+P + E++++ +   +  +   I  L+P++G + T   LLP+ +   KD  P ++ N+   L  +  ++    + +S+ P +VEL+ED    VR
Sbjct:  204 EIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 420          

BLAST of CK934495 vs. ExPASy Swiss-Prot
Match: 2AAA_HUMAN (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens GN=PPP2R1A PE=1 SV=4)

HSP 1 Score: 267.314 bits (682), Expect = 6.461e-71
Identity = 133/223 (59.64%), Postives = 173/223 (77.58%), Query Frame = 1

Query:    4 TIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVRFFATQAL 672
            TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI  LSQSLLPAIVELAED  WRVRLAIIEY+PLLA QLGV FFD+KL +LCM WL D VY+IR+AA +N+K+L E+FG +WA   I+P+VL M  +P+YL+RMT L  I++L+ V G +IT   +LP V+  + D V N++FNVAK LQ + PI+D S ++  ++P L +L++D DVDV++FA +AL
Sbjct:  361 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL 583          

HSP 2 Score: 94.3597 bits (233), Expect = 7.496e-19
Identity = 56/217 (25.81%), Postives = 104/217 (47.93%), Query Frame = 1

Query:   13 QLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDW----AMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVR 651
            +++P+F +L  DE   VRL  +     + Q++  + L   ++P + + AED+ WRVR  + +    L   +G       L       +KD    +R AA++ VK   E    D      M  I+P + E++++ +   +  +   I  L+P++G + T   LLP+ +   KD  P ++ N+   L  +  ++    + +S+ P +VEL+ED    VR
Sbjct:  204 EIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 420          

BLAST of CK934495 vs. ExPASy Swiss-Prot
Match: 2AAA_SCHPO (Protein phosphatase PP2A regulatory subunit A OS=Schizosaccharomyces pombe GN=paa1 PE=2 SV=1)

HSP 1 Score: 261.151 bits (666), Expect = 4.630e-69
Identity = 132/228 (57.89%), Postives = 175/228 (76.75%), Query Frame = 1

Query:    4 TIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIV----DQSVVEKSIRPCLVELSEDPDVDVRFFATQALQ 675
            T E LLP+FL LLKDE P+VRLNIISKL+ VN+V+GI+LLSQSLLPAIV LAED+ WRVRLAII+YIPLLA QLGV FF++K+G LCM WL+D VYSIR+AA  N+++L E FG +WA + I+P+ L M ++P+YLYRMT + AIS +AP + +E+   Q+LP +     D +PNI+FNVAK  + L P++    D +V E+ I P L +L++D D DV++FATQAL+
Sbjct:  359 TTEYLLPMFLELLKDENPEVRLNIISKLEVVNKVVGIELLSQSLLPAIVTLAEDKQWRVRLAIIDYIPLLAQQLGVEFFNEKMGNLCMSWLEDHVYSIREAAIKNLRKLTEIFGLEWATETIIPKFLAMRSHPNYLYRMTTIFAISEIAPALNAEVIEKQILPTLEQLVNDPIPNIRFNVAKAFEVLKPVLAAGGDSTVYEQQIIPLLEQLTKDNDPDVQYFATQALE 586          

HSP 2 Score: 90.8929 bits (224), Expect = 8.288e-18
Identity = 59/216 (27.31%), Postives = 99/216 (45.83%), Query Frame = 1

Query:    7 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDL-LSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVR 651
            I++ +P+F SL  D+   VRL     +  + +V+  D  +   LL  +     D  WR R  +      LA  +G     D+L    +  +KD    +R A A  +    E       ++ I+P + E+IN+P    R  +   I  LAP +G E T   LLP+ +   KD  P ++ N+   L+ +  +V   ++ +S+ P +V L+ED    VR
Sbjct:  203 IDEFIPLFNSLSNDDQDSVRLLSFDIMVSLAEVLKSDSEIRHYLLQPLRSFVSDSSWRTRYMVAANFVKLAKVVGPSLIKDELIKPFVLLMKDTEQEVRRAIATQIPGFCELLDKRIVLEEIIPVIQELINDPAQHVRAALGMNIGALAPQLGKEKTTEYLLPMFLELLKDENPEVRLNIISKLEVVNKVVGIELLSQSLLPAIVTLAEDKQWRVR 418          

BLAST of CK934495 vs. ExPASy Swiss-Prot
Match: 2AAA_DROME (Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit OS=Drosophila melanogaster GN=Pp2A-29B PE=1 SV=4)

HSP 1 Score: 257.299 bits (656), Expect = 6.686e-68
Identity = 131/223 (58.74%), Postives = 164/223 (73.54%), Query Frame = 1

Query:    4 TIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVRFFATQAL 672
            T+EQLLP+FL  LKDE P+VRLNIIS LD VN VIGI  LSQSLLPAIVELAED  WRVRLAIIEY+P LA QLG  FFD KL  LCM WL D VY+IR+AA  N+K+L E+FG  WA Q I+P +L M  N +YL+RMT L  +++LA V G++IT   LLP V+  + D V N++FNVAK LQ + P ++ SV++  ++P L +L+ D DVDV+ FA QA+
Sbjct:  363 TVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQLGQEFFDQKLRGLCMGWLNDHVYAIREAATLNMKKLVEQFGAPWAEQAIIPMILVMSRNKNYLHRMTCLFCLNVLAEVCGTDITTKLLLPTVLLLAADPVANVRFNVAKTLQKISPFLEASVIDAQVKPTLDKLNTDTDVDVKHFAAQAI 585          

HSP 2 Score: 85.5001 bits (210), Expect = 3.482e-16
Identity = 58/216 (26.85%), Postives = 100/216 (46.30%), Query Frame = 1

Query:   16 LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQ----HIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVR 651
            L+P F+ L +D+   VRL  +     + Q++  D +   +LP + + A D  WRVR  + E    L   +G       L       LKD    +R A A  VK           +Q     I+P V +++++P+   +  +   I  L+P++G+  T  QLLP+ +   KD  P ++ N+   L  +  ++    + +S+ P +VEL+ED    VR
Sbjct:  207 LIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCANLDKVNQVQIILSSILPYVRDLVSDPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVR 422          

BLAST of CK934495 vs. ExPASy Swiss-Prot
Match: 2AAA_YEAST (Protein phosphatase PP2A regulatory subunit A OS=Saccharomyces cerevisiae GN=TPD3 PE=1 SV=2)

HSP 1 Score: 223.402 bits (568), Expect = 1.070e-57
Identity = 116/239 (48.54%), Postives = 165/239 (69.04%), Query Frame = 1

Query:    7 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQV----LEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQ------SVVEKSIRPCLVELSEDPDVDVRFFATQALQSKDQVM 693
            I   LPI L++L+DEFPDVRLNII+ L  VN VIGI+LLS SLLPAI ELA+D +WRVR+AIIEYIP+LA QLG+ FFD +L  LC+ WL D VYSIR+AA NN+KRL E FG DW    I+ ++    L+++ N  ++ R TIL A++ L PV+  ++   QLLP + + + D VPNI+FNVAK    ++ ++ +      ++++ +I P L  L +D DVDV++FA ++L    +++
Sbjct:  397 INNFLPILLNMLRDEFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAKDVNWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIFGSDWCRDEIISRLLKFDLQLLEN--FVSRFTILSALTTLVPVVSLDVVTEQLLPFISHLADDGVPNIRFNVAKSYAVIVKVLIKDEAKYDALIKNTILPSLQTLFQDEDVDVKYFAKKSLAECQELL 633          

BLAST of CK934495 vs. ExPASy Swiss-Prot
Match: 2AAA_CAEEL (Probable serine/threonine-protein phosphatase PP2A regulatory subunit OS=Caenorhabditis elegans GN=paa-1 PE=2 SV=2)

HSP 1 Score: 213.001 bits (541), Expect = 1.446e-54
Identity = 107/225 (47.56%), Postives = 156/225 (69.33%), Query Frame = 1

Query:    4 TIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQVLEMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVRFFATQALQS 678
            T+ +LLPI++ LL D+ P+VRLNIIS LD+VN+VIG   LS SLLPAIV LAED  WRVRLAI++++PLLASQLG  FFD+KL  LC+ WL D V+SIR+A+   +K L ++FG  WA  +IVP++ ++  + +YL RMT L  ++ L+  M  E    +++P+V +  +D VPN++FN AK L+ +   +  S +   ++P L +L +D D DVR+F+ +A  S
Sbjct:  363 TVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRVRLAIVQFMPLLASQLGQEFFDEKLLPLCLNWLTDHVFSIREASTLIMKELTQKFGGQWASTNIVPKMQKLQKDTNYLQRMTCLFCLNTLSEAMTQEQILKEIMPIVKDLVEDDVPNVRFNAAKSLKRIGKNLTPSTLTSEVKPLLEKLGKDSDFDVRYFSEEAKNS 587          

HSP 2 Score: 77.0258 bits (188), Expect = 1.238e-13
Identity = 57/224 (25.45%), Postives = 98/224 (43.75%), Query Frame = 1

Query:    7 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLKDKVYSIRDAAANNVKRLAEEFGPDWAMQHIVPQVL----EMINNPHYLYRMTILQAISLLAPVMGSEITCSQLLPVVINASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKSIRPCLVELSEDPDVDVRFFATQ 666
            IE L      L  DE   VRL  +        ++      + + P ++EL +D+ WRVR  + E +  + + LG       L  +    LKD    +R AA   ++  A     D     I   +L    E++ + + L +  +   I  LAP++G E T S+LLP+ +    D+ P ++ N+   L  +  ++  + +  S+ P +V L+ED    VR    Q
Sbjct:  204 IEGLHSSLTDLHVDEQDSVRLLTVESAIAFGTLLDKANKKKLIEPILIELFDDKSWRVRYMVAEKLIEIQNVLGEDMDTTHLVNMYTNLLKDPEGEVRCAATQRLQEFALNLPEDKRQNIICNSLLNVAKELVTDGNQLVKSELAGVIMGLAPLIGKEQTVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRVRLAIVQ 427