EY754093

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_PONAB (Alcohol dehydrogenase [NADP+] OS=Pongo abelii GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 1.298e-38
Identity = 61/176 (34.66%), Postives = 94/176 (53.41%), Query Frame = 3

Query:  330 LMHWPVRTKKGF--ISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDL 830
            LMHWP   ++G      N +  +  D  +   TWKA+EAL   G  RA+G+SNF+ +++ D+L VA V PAV QVECHP   Q +L   C ++G+ V            W   D   +L+ PV+  +AEK G +P Q+ +RW +Q     +PK    +   ++  VF ++  PE++
Sbjct:  111 LMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVRALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLAVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGGSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEM 286          

HSP 2 Score: 77.7962 bits (190), Expect = 1.298e-38
Identity = 40/74 (54.05%), Postives = 48/74 (64.86%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            L+ G KMP IGLGTW+++PG V          GYRHIDCA  YGNE EIG  LK+    G  V RE+L++TSKL
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKL 81          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.298e-38
Identity = 57/184 (30.98%), Postives = 90/184 (48.91%), Query Frame = 3

Query:  330 LMHWPVR---------TKKGFISLNPEDLLQP-DIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGI 851
            L+HWP+          T +     N   ++ P  I  TW+ ME L + G  ++IGVSNF+V+ L DLL  A++ P VNQVE HP   Q KL E+C+   I +              K D   + ++K +A K  K+   V  +W+ Q G + +PK  N +    +F++F + +  D   K + +
Sbjct:  122 LIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQG-----KCDFFSNKILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNIFDFQLSNDDIEKINSL 300          

HSP 2 Score: 85.1149 bits (209), Expect = 1.298e-38
Identity = 44/86 (51.16%), Postives = 59/86 (68.60%), Query Frame = 1

Query:   88 NDNVQY----FELNNGAKMPSIGLGTWQAQ-PGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            N+N  Y    F+LN+G ++PSIGLGT+ ++ PG V          GYRHID A FYGNEK IG  LK++F++G +KRED++ TSKL
Sbjct:    7 NNNTNYNNNNFKLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIKREDIFYTSKL 92          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: A1A1A_DANRE (Alcohol dehydrogenase [NADP+] A OS=Danio rerio GN=akr1a1a PE=2 SV=2)

HSP 1 Score: 108.227 bits (269), Expect = 4.870e-38
Identity = 60/174 (34.48%), Postives = 95/174 (54.60%), Query Frame = 3

Query:  330 LMHWPVRTKKG--FISLNPEDLLQPD---IPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWF---KSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPED 827
            L+HWP+   +G   I  +P+  +Q D     +TW AME L D G A+AIG+SNF+ K++ D+L +A+  P VNQVECHP   Q +L   C S+ + V            W    ++ +L  P +  +A+   KTP QV IRW +Q G   +PK    +  +++ +VF + + ++
Sbjct:  110 LIHWPMAFGRGDELIPRHPDGTIQYDDTHYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHKPVVNQVECHPYLVQAELVSHCWSRNLTVTAYSPLGSPDRPWVTPGEALLLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVVCIPKSVTPSRIKQNIEVFDFKLSDE 283          

HSP 2 Score: 71.633 bits (174), Expect = 4.870e-38
Identity = 33/74 (44.59%), Postives = 48/74 (64.86%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            L+ G +MP++GLGTW++ PG V          GYRHIDCA  Y NE+E+G  L +    G  ++R+D+++TSKL
Sbjct:    7 LSTGQRMPTVGLGTWKSAPGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKL 80          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1BA_HUMAN (Aldo-keto reductase family 1 member B10 OS=Homo sapiens GN=AKR1B10 PE=1 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 2.382e-37
Identity = 65/185 (35.14%), Postives = 90/185 (48.65%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPEDLLQPD-----------IPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVA--RVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFA 836
            L+HWP   K G      +DL   D             + W+AME L D G  +A+GVSNFS  +++ LL     +  P  NQVECHP   QEKL ++C+SKGI V            W K +   +L+ P IK +A K  KT  QV IR+ +Q    V+PK    A    +  VF + + ++  A
Sbjct:  109 LIHWPQGFKSG------DDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287          

HSP 2 Score: 78.9518 bits (193), Expect = 2.382e-37
Identity = 37/76 (48.68%), Postives = 49/76 (64.47%), Query Frame = 1

Query:  103 YFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            + EL+  AKMP +GLGTW++  G V          GYRHIDCAY Y NE E+G  +++  ++  VKREDL+I SKL
Sbjct:    4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKL 79          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: 6DCS_SOYBN (NAD(P)H-dependent 6'-deoxychalcone synthase OS=Glycine max PE=1 SV=1)

HSP 1 Score: 129.413 bits (324), Expect = 4.042e-37
Identity = 69/181 (38.12%), Postives = 106/181 (58.56%), Query Frame = 3

Query:  330 LMHWPVRTKKGFIS--LNPEDLLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIEQAKL 866
            L+HWP+ ++ G  S  +  EDLL  D+   W++ME     G  +AIGVSNFSVKKLQ+LL VA + P V+QVE +  W+Q+KL EFC   GI V               ++V+++ V+K +AE  GK+  QV +RW+ + G + +PK  ++    ++  +F W++ E    K S I Q++L
Sbjct:  119 LIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPLRKGASRG-PNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKSYDKERMNQNLHIFDWALTEQDHHKISQISQSRL 298          

HSP 2 Score: 47.3654 bits (111), Expect = 4.042e-37
Identity = 21/41 (51.22%), Postives = 29/41 (70.73%), Query Frame = 1

Query:  208 GYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            GYRH D A  YG+E+ +G  LK+    G+V R+DL++TSKL
Sbjct:   49 GYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKL 89          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: A1A1B_DANRE (Alcohol dehydrogenase [NADP+] B OS=Danio rerio GN=akr1a1b PE=2 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 6.857e-37
Identity = 59/184 (32.07%), Postives = 92/184 (50.00%), Query Frame = 3

Query:  330 LMHWPVRTKKG---FISLNPEDLLQPDIPN--TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIEQ 857
            L+HWP   ++G   F       LL  DI    TW AME L   G  RAIG+SNF+ +++ D+L VA + P V QVE HP   Q +L   C  +G+ +            W   D   +L+ P I  +A+K  KTP Q+ IRW  Q G   +PK   ++  + +  VF +++  +  ++ + + +
Sbjct:  110 LIHWPYAFQRGDTPFPRKEDGTLLYDDIDYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILSVASIKPTVLQVESHPYLAQVELLSHCRDRGLVMTAYSPLGSPDRAWKHPDEPVLLEEPAIAALAKKYNKTPAQIIIRWQTQRGVVTIPKSITQSRIKENIQVFDFTLESEEMSQVTALHR 293          

HSP 2 Score: 73.9442 bits (180), Expect = 6.857e-37
Identity = 35/74 (47.30%), Postives = 49/74 (66.22%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKK-LFEDGVVKREDLWITSKL 330
            L+ G KMP +GLGTW+++PG+V          GYRHIDCA  Y NE EIG   ++ +  D  ++RED+++TSKL
Sbjct:    7 LSTGRKMPLLGLGTWKSEPGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKL 80          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: GCY_YEAST (Protein GCY OS=Saccharomyces cerevisiae GN=GCY1 PE=1 SV=1)

HSP 1 Score: 105.916 bits (263), Expect = 8.937e-37
Identity = 76/210 (36.19%), Postives = 103/210 (49.05%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPEDLLQP----------DIPN-----TWKAMEALYDSGKARAIGVSNFSVKKLQDLL--KVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPE----DLFAKFSGIEQAKLSLWSTFSSMK 896
            LMHWP R    +I    ED+L            DI N     TW+ M+ L  +GK +A+GVSNFS+  L+DLL  +  ++TPA NQVE HP   Q++L  FC SKGI V               + +LK PVI  +A+K    PG V I W +Q GY VLPK  N    + +  +F  S  +    +  +K  G ++     WS F   K
Sbjct:  110 LMHWPARLDPAYIK--NEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGST-----DAPLLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFTLSTEDFEAINNISKEKGEKRVVHPNWSPFEVFK 312          

HSP 2 Score: 69.707 bits (169), Expect = 8.937e-37
Identity = 35/89 (39.33%), Postives = 50/89 (56.18%), Query Frame = 1

Query:   73 MDQIANDNVQYFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*CT 339
            M    +D+ +   LN GA++P IGLGTWQ++              GYRHID A  Y NE ++G  +K    D  V RE++++T+KL CT
Sbjct:    1 MPATLHDSTKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK----DSGVPREEIFVTTKLWCT 85          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: XYL1_PACTA (NAD(P)H-dependent D-xylose reductase OS=Pachysolen tannophilus GN=XYL1 PE=1 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 3.351e-36
Identity = 64/179 (35.75%), Postives = 87/179 (48.60%), Query Frame = 3

Query:  330 LMHWPVRTK---------KGFISLNPEDLLQPDIP--NTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLK-------HPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXC--NEAGXQRHFDVF 806
            LMH+P+  K          GF   + +  +  D+P   TW+AME L D G  ++IGVSN S   L+DL+K AR+ PA  Q+E HP  +Q KL E+   KGI V               ++  K       +  I  +A K GKTP QV +RWV Q G +++PK    N      H D F
Sbjct:  108 LMHFPISFKFVPFEEKYPPGFYCGDGDKFIYEDVPIIETWRAMENLVDEGLVKSIGVSNVSGGLLEDLIKAARIKPASLQIEHHPYLQQNKLVEYAQLKGIVVTGYSNFGPLSFLELGNETAKKTQPLYENKTITTIAAKHGKTPFQVLLRWVNQRGIAIIPKSTFPNTLAVNLHVDEF 286          

HSP 2 Score: 77.7962 bits (190), Expect = 3.351e-36
Identity = 37/78 (47.44%), Postives = 51/78 (65.38%), Query Frame = 1

Query:   97 VQYFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            +QY+ LNNG K+P+IG+G W+ +              GYR  DCA  YGNEKE+G  + +  +DG+VKR+DL+ITSKL
Sbjct:    3 LQYYTLNNGRKIPAIGMGCWKLENAA--DMVYAAIKEGYRLFDCACDYGNEKEVGEGINRAIKDGLVKRKDLFITSKL 78          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.639e-35
Identity = 54/167 (32.34%), Postives = 84/167 (50.30%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPEDLLQP--DIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPE 824
            L+HWPV  +     +      Q    I  TW+ ME L D+G  ++IG+SNF+V+ L ++L  AR+ PA NQVE HP   Q +L +FC+   IH+                  + +  +  +A+K  KT   V  +W +Q  +SV+PK    +    +FD+F + I E
Sbjct:  110 LVHWPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLG-------NGAFVDNEEVGAIAKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEIEE 269          

HSP 2 Score: 74.3294 bits (181), Expect = 1.639e-35
Identity = 37/76 (48.68%), Postives = 49/76 (64.47%), Query Frame = 1

Query:  106 FELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTEL-KKLFEDGVVKREDLWITSKL 330
            F+L++G K+P +G GTW+A+  +V          GYRHIDCA  Y NEKE+G    KK   +  VKRED++ITSKL
Sbjct:    5 FKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKL 80          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: ALD2_MOUSE (Aldose reductase-related protein 2 OS=Mus musculus GN=Akr1b8 PE=1 SV=2)

HSP 1 Score: 90.5077 bits (223), Expect = 1.042e-34
Identity = 63/187 (33.69%), Postives = 93/187 (49.73%), Query Frame = 3

Query:  312 MDHLQA-LMHWPVRTKKGFISLNPED------LLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVT--PAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFA 836
            +D+L   L+HWP   + G   L P+D        +      W+ ME L D G  +A+GVSNF+  +++ LL    +   P  NQVECHP   QEKL ++C+SKGI V              K +   +L+ P IK +A K  KT  QV IR+ +Q    V+PK    +  Q +  VF + + ++  A
Sbjct:  102 LDYLDLYLIHWPQGLQPGK-ELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMA 287          

HSP 2 Score: 78.1814 bits (191), Expect = 1.042e-34
Identity = 36/76 (47.37%), Postives = 49/76 (64.47%), Query Frame = 1

Query:  103 YFELNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            + EL+  AKMP +GLGTW++ P  V          GYRHIDCAY Y NE E+G  +++  ++  V+REDL+I SKL
Sbjct:    4 FVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQREDLFIVSKL 79