EY754093

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1A1_CRIGR (Alcohol dehydrogenase [NADP+] (Fragment) OS=Cricetulus griseus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 8.979e-30
Identity = 49/133 (36.84%), Postives = 73/133 (54.89%), Query Frame = 3

Query:  330 LMHWPVRTKKGF--ISLNPEDLLQPDIPN---TWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGK 704
            LMHWP   ++G      N +  ++ D  +   TWKA+EAL   G  +A+G+SNF+ +++ D+L VA V PAV QVECHP   Q +L   C ++G+ V            W   D   +L+ PV+  +AEK G+
Sbjct:   96 LMHWPYAFERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGR 228          

HSP 2 Score: 66.6254 bits (161), Expect = 8.979e-30
Identity = 35/65 (53.85%), Postives = 41/65 (63.08%), Query Frame = 1

Query:  139 IGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDG-VVKREDLWITSKL 330
            IGLGTW++ PG V          GYRHIDCA  YGNE EIG  LK+    G  V RE+L++TSKL
Sbjct:    2 IGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKL 66          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 1.512e-29
Identity = 61/177 (34.46%), Postives = 94/177 (53.11%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPED---LLQP--DIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWRQEKLHEFCNSKGI-HVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPED 827
            L+H+P+  K G   L  ++   L+    DI +TW+AME   D+G A++IGVSNF+ ++L+ +LK    +  P  NQVECHP   Q KL +FC SK I  V            W       +L +PV+  +A+K  +TP  + +R+ LQ G  VL K  +E   + +  VF + +  +
Sbjct:  115 LIHFPMAMKPGENYLPKDENGKLIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAYSALGSHREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSE 291          

HSP 2 Score: 59.6918 bits (143), Expect = 1.512e-29
Identity = 32/83 (38.55%), Postives = 44/83 (53.01%), Query Frame = 1

Query:  100 QYFELNNGAKMPSIGLGTWQAQP---GVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*CT 339
            Q   L++G  +P +G GT+  Q                 G+RHID A  Y NEKE+G  ++    DG VKRED++ TSK+ CT
Sbjct:    6 QTVRLSDGHFIPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVKREDIFYTSKVWCT 88          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1C1_HUMAN (Aldo-keto reductase family 1 member C1 OS=Homo sapiens GN=AKR1C1 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.968e-29
Identity = 61/188 (32.45%), Postives = 97/188 (51.60%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPED------LLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVA--RVTPAVNQVECHPGWRQEKLHEFCNSKGI-HVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIEQ 857
            L+H+PV  K G   + P+D          D+  TW+A+E   D+G A++IGVSNF+ ++L+ +L     +  P  NQVECHP + Q KL +FC SK I  V            W   +   +L+ PV+  +A+K  +TP  + +R+ LQ G  VL K  NE   +++  VF + +  +      G+ +
Sbjct:  115 LIHFPVSVKPGE-EVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301          

HSP 2 Score: 60.8474 bits (146), Expect = 1.968e-29
Identity = 31/82 (37.80%), Postives = 45/82 (54.88%), Query Frame = 1

Query:  100 QYFELNNGAKMPSIGLGTW---QAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*C 336
            Q  +LN+G  MP +G GT+   +                G+RHID A+ Y NE+++G  ++    DG VKRED++ TSKL C
Sbjct:    6 QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWC 87          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1C1_PONAB (Aldo-keto reductase family 1 member C1 homolog OS=Pongo abelii GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 2.563e-29
Identity = 62/188 (32.98%), Postives = 97/188 (51.60%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPED------LLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWRQEKLHEFCNSKGI-HVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIEQ 857
            L+H+PV  K G   + P+D          D+  TW+AME   D+G A++IGVSNF+ ++L+ +L     +  P  NQVECHP + Q KL +FC SK I  V            W   +   +L+ PV+  +A+K  +TP  + +R+ LQ G  VL K  NE   +++  VF + +  +      G+ +
Sbjct:  115 LVHFPVSVKPGE-EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEKWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNMQVFDFQLTSEDMKTIDGLNR 301          

HSP 2 Score: 58.9214 bits (141), Expect = 2.563e-29
Identity = 33/83 (39.76%), Postives = 46/83 (55.42%), Query Frame = 1

Query:  100 QYFELNNGAKMPSIGLGTWQAQPGV----VXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*C 336
            Q  +LN+   MP +G GT+ A P V               G+RHID A+ Y NE+++G  ++    DG VKRED++ TSKL C
Sbjct:    6 QCVKLNDSHFMPVLGFGTY-APPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWC 87          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFA (Aldo-keto reductase family 1 member C4 OS=Macaca fascicularis GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 2.563e-29
Identity = 57/177 (32.20%), Postives = 90/177 (50.85%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPED-----LLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVA--RVTPAVNQVECHPGWRQEKLHEFCNSKGI-HVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPED 827
            L+H+P+  K G   L  ++         D+   W+AME   D+G A++IGVSNF+ ++L+ +L     +  P  NQVECHP   Q KL +FC SK I  V            W   +   +L+ PV+  +A+K  ++P  + +R+ LQ G  VL K  NE   + +  VF + +  +
Sbjct:  115 LIHFPMALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSE 291          

HSP 2 Score: 65.855 bits (159), Expect = 2.563e-29
Identity = 37/84 (44.05%), Postives = 48/84 (57.14%), Query Frame = 1

Query:  100 QYFELNNGAKMPSIGLGTWQAQPGV----VXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*CT 339
            Q   LN+G  MP +G GT+ A P V    V          G+RHID AY Y NE+++G  ++    DG VKRED++ TSKL CT
Sbjct:    6 QRVALNDGHFMPVLGFGTY-APPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCT 88          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: Y1919_MYCSJ (Uncharacterized oxidoreductase Mjls_1919 OS=Mycobacterium sp. (strain JLS) GN=Mjls_1919 PE=3 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 2.570e-29
Identity = 61/177 (34.46%), Postives = 86/177 (48.59%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPEDLLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIEQA 860
            L+HWPV  K  F+             +T++A   L + G+ R+IGVSNF  + L+ L+    + PAVNQ+E HP   Q +L E     GI                +  +L HP +  VAE  GKT  Q  IRW +Q+G  V+PK  N    + +FDVF + + E   A  S +E A
Sbjct:  106 LIHWPVPEKNLFV-------------DTFRAFARLREDGRIRSIGVSNFEPEHLRVLIDSTGIVPAVNQIELHPLLPQRELRELHAQLGIATEAWSPLG-------QGSLLAHPTVTGVAESHGKTAAQALIRWHMQLGNIVIPKSVNPQRIESNFDVFDFELSEQDMASISSLEDA 262          

HSP 2 Score: 50.0618 bits (118), Expect = 2.570e-29
Identity = 25/73 (34.25%), Postives = 39/73 (53.42%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            LN+G  +P +GLG WQ  P             GYRH+D A  YGNE++ G   + + + G + R  +++ +KL
Sbjct:    8 LNDGNSIPQVGLGVWQTPPEDTERAVAAALAAGYRHVDTAAAYGNEEQTG---RAIAQSG-LDRSQVYLVTKL 76          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: PGFS1_BOVIN (Prostaglandin F synthase 1 OS=Bos taurus PE=1 SV=3)

HSP 1 Score: 91.2781 bits (225), Expect = 3.337e-29
Identity = 63/181 (34.81%), Postives = 95/181 (52.49%), Query Frame = 3

Query:  330 LMHWPVRTKKG--FISLNPEDLL---QPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWRQEKLHEFCNSKGI-HVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDLFA 836
            ++H PV  K G  F+  +    L     D+ +TW+A+E   D+G  ++IGVSNF+ K+L+ +L     +  P  NQVECHP   Q KL EFC S  I  V            W  S+   +L+ PV+  +A+K  +TP  V +R+ +Q G  VL K  N+   + +  VF + + PED+ A
Sbjct:  115 IIHSPVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKA 295          

HSP 2 Score: 58.9214 bits (141), Expect = 3.337e-29
Identity = 29/82 (35.37%), Postives = 45/82 (54.88%), Query Frame = 1

Query:  100 QYFELNNGAKMPSIGLGTW---QAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL*C 336
            Q  +LN+G  +P +G GT+   +                G+RH+D A+ Y NE+++G  ++    DG VKRED++ TSKL C
Sbjct:    6 QRVKLNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTVKREDIFYTSKLWC 87          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 3.337e-29
Identity = 55/178 (30.90%), Postives = 89/178 (50.00%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPED------LLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSD----VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPED 827
            L+H+PV  K G   L P+D      L   D+ +TW+AME   D+G A++IGVSNF+ ++L+ +L     +  P  NQVECH    Q KL  +C    I +            +  ++    +L  P++  +A+K  +TP  + +R+ L+ G   L K  NE   + +  VF + +  D
Sbjct:  115 LIHFPVSLKPGD-ELLPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQVFDFQLASD 291          

HSP 2 Score: 69.3218 bits (168), Expect = 3.337e-29
Identity = 34/84 (40.48%), Postives = 48/84 (57.14%), Query Frame = 1

Query:   88 NDNVQYFELNNGAKMPSIGLGTWQAQPGV---VXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            N  +Q  ELN+G  +P +G GT+  +  +              G+RHIDC++ Y NE+EIG  +    EDG VKRED++ TSKL
Sbjct:    2 NSKIQKMELNDGHSIPVLGFGTYATEENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTVKREDIFYTSKL 85          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: Y1985_MYCSK (Uncharacterized oxidoreductase Mkms_1985 OS=Mycobacterium sp. (strain KMS) GN=Mkms_1985 PE=3 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 3.346e-29
Identity = 61/175 (34.86%), Postives = 85/175 (48.57%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPEDLLQPDIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKVARVTPAVNQVECHPGWRQEKLHEFCNSKGIHVXXXXXXXXXXXXWFKSDVLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSIPEDLFAKFSGIE 854
            L+HWPV  K  F+             +T+KA   L + G+ R+IGVSNF  + L+ L+    + PAVNQ+E HP   Q +L E     GI                +  +L HP +  VAE  GKT  Q  IRW +Q+G  V+PK  N    + +FDVF + + E   A  S +E
Sbjct:  106 LIHWPVPEKNLFV-------------DTFKAFARLREDGRIRSIGVSNFEPEHLRVLIDSTGIVPAVNQIELHPLLPQRELRELHAQLGIATEAWSPLG-------QGSLLAHPTVTGVAESHGKTAAQALIRWHMQLGNIVIPKSVNPQRIESNFDVFDFELSEQDMASISSLE 260          

HSP 2 Score: 50.0618 bits (118), Expect = 3.346e-29
Identity = 25/73 (34.25%), Postives = 39/73 (53.42%), Query Frame = 1

Query:  112 LNNGAKMPSIGLGTWQAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            LN+G  +P +GLG WQ  P             GYRH+D A  YGNE++ G   + + + G + R  +++ +KL
Sbjct:    8 LNDGNSIPQVGLGVWQTPPEDTERAVAAALAAGYRHVDTAAAYGNEEQTG---RAIAQSG-LDRSQVYLVTKL 76          

BLAST of EY754093 vs. ExPASy Swiss-Prot
Match: DDBX_BOVIN (Dihydrodiol dehydrogenase 3 OS=Bos taurus PE=2 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 4.344e-29
Identity = 60/181 (33.15%), Postives = 95/181 (52.49%), Query Frame = 3

Query:  330 LMHWPVRTKKGFISLNPEDLLQP-----DIPNTWKAMEALYDSGKARAIGVSNFSVKKLQDLLKV--ARVTPAVNQVECHPGWRQEKLHEFCNSKGI-HVXXXXXXXXXXXXWFKSD---VLKHPVIKMVAEKLGKTPGQVCIRWVLQMGYSVLPKXCNEAGXQRHFDVFGWSI-PEDLFA 836
            ++H+PV  K G      ++  +P     D+  TW+A+E   D+G  ++IGVSNF+ K+L+ +L     +  P  NQVECHP + Q KL +FC S  I  V            W   +   +L+ PV+  +A+K  +TP  V +R+ +Q G  VL K  N+   + +  VF + + PED+ A
Sbjct:  115 IIHFPVALKPGETLFPTDENGKPIFDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYFNQSKLLDFCKSHDIVLVAYGALGSQRLKEWVNPNLPFLLEDPVLSAIAKKHRQTPALVALRYQIQRGVVVLAKSYNKKRIKENIQVFDFELTPEDMKA 295          

HSP 2 Score: 56.9954 bits (136), Expect = 4.344e-29
Identity = 29/80 (36.25%), Postives = 44/80 (55.00%), Query Frame = 1

Query:  100 QYFELNNGAKMPSIGLGTW---QAQPGVVXXXXXXXXXXGYRHIDCAYFYGNEKEIGTELKKLFEDGVVKREDLWITSKL 330
            Q  +LN+G  +P +G GT+   +                G+RHID A+ Y NE+++G  ++    DG VKRED++ TSKL
Sbjct:    6 QRVKLNDGHFIPVLGFGTFAPREVPKSEALEVTKFAIEAGFRHIDSAHLYQNEEQVGQAIRSKIADGTVKREDIFYTSKL 85