EY727705

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS_YEAST (Hydroxymethylglutaryl-CoA synthase OS=Saccharomyces cerevisiae GN=ERG13 PE=1 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 3.135e-28
Identity = 53/96 (55.21%), Postives = 70/96 (72.92%), Query Frame = 2

Query:  257 KAMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            K   +NVGI  + IY P  CV Q  LE  DG S+GKYTIGLGQ  M+F ++ ED+ SMSLT ++ L++ Y ID  +IGRLEVG+ET+I+KSKS+K+
Sbjct:   43 KTRPQNVGIKGIQIYIPTQCVNQSELEKFDGVSQGKYTIGLGQTNMSFVNDREDIYSMSLTVLSKLIKSYNIDTNKIGRLEVGTETLIDKSKSVKS 138          

HSP 2 Score: 36.965 bits (84), Expect = 3.135e-28
Identity = 19/52 (36.54%), Postives = 32/52 (61.54%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHACLRRTGGLFYWGNGVKSISGNGR 680
            ++  ++  LMQ+F    NTD+EG+D+ +AC   T  LF   N ++S + +GR
Sbjct:  132 KSKSVKSVLMQLFGE--NTDVEGIDTLNACYGGTNALFNSLNWIESNAWDGR 181          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS2_RAT (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Rattus norvegicus GN=Hmgcs2 PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 4.079e-28
Identity = 48/92 (52.17%), Postives = 65/92 (70.65%), Query Frame = 2

Query:  269 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            K+VGILA+++YFP   V Q  LE  +    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ K+    +GRLEVG+ET+I+KSK++KT
Sbjct:   52 KDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKT 143          

HSP 2 Score: 47.3654 bits (111), Expect = 4.079e-28
Identity = 21/52 (40.38%), Postives = 35/52 (67.31%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHACLRRTGGLFYWGNGVKSISGNGR 680
            ++  ++  LM++F++ GNTDIEG+D+T+AC   T  LF   N ++S   +GR
Sbjct:  137 KSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGR 188          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS2_MOUSE (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Mus musculus GN=Hmgcs2 PE=1 SV=2)

HSP 1 Score: 99.3673 bits (246), Expect = 4.079e-28
Identity = 48/92 (52.17%), Postives = 65/92 (70.65%), Query Frame = 2

Query:  269 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            K+VGILA+++YFP   V Q  LE  +    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ K+    +GRLEVG+ET+I+KSK++KT
Sbjct:   52 KDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKT 143          

HSP 2 Score: 47.3654 bits (111), Expect = 4.079e-28
Identity = 21/52 (40.38%), Postives = 35/52 (67.31%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHACLRRTGGLFYWGNGVKSISGNGR 680
            ++  ++  LM++F++ GNTDIEG+D+T+AC   T  LF   N ++S   +GR
Sbjct:  137 KSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGR 188          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS2_PIG (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Sus scrofa GN=HMGCS2 PE=2 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 4.079e-28
Identity = 47/92 (51.09%), Postives = 64/92 (69.57%), Query Frame = 2

Query:  269 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            K+VGILA+++YFP   V Q  LE  D    G+YT+GLGQ  M FCS  ED+ S+ LT V  L+E+ ++    +G LEVG+ET+I+KSKS+KT
Sbjct:   52 KDVGILALEVYFPAQYVDQTDLEKFDNVEAGRYTVGLGQTHMGFCSVQEDINSLCLTVVQRLMERTQLPWDSVGWLEVGTETIIDKSKSVKT 143          

HSP 2 Score: 49.6766 bits (117), Expect = 4.079e-28
Identity = 22/52 (42.31%), Postives = 36/52 (69.23%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHACLRRTGGLFYWGNGVKSISGNGR 680
            ++  ++  LM++F++ GNTDIEG+D+T+AC   T  LF   N V+S + +GR
Sbjct:  137 KSKSVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWVESSAWDGR 188          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS1_BLAGE (Hydroxymethylglutaryl-CoA synthase 1 OS=Blattella germanica GN=HMGCS-1 PE=2 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 9.676e-27
Identity = 48/91 (52.75%), Postives = 68/91 (74.73%), Query Frame = 2

Query:  272 NVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            +VGI+A+++ FP   V Q  LE +D  S GKYT+GLGQ  M FC++ ED+ S+ LT V+ L+E++ I   QIGRLEVG+ET+++KSKS+KT
Sbjct:    5 DVGIVALELIFPSQYVDQVDLEVYDNVSAGKYTVGLGQARMGFCTDREDINSLCLTVVSRLMERWSIPYSQIGRLEVGTETLLDKSKSVKT 95          

HSP 2 Score: 40.4318 bits (93), Expect = 9.676e-27
Identity = 27/68 (39.71%), Postives = 39/68 (57.35%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHACLRRTGGLFYWGNGVKSISGNGRLGPRWGSRTWGVYAKG 728
            ++  ++  LMQ+F++  NTDIEGVD+ +AC   T  LF   + V+S S +GR           VYAKG
Sbjct:   89 KSKSVKTVLMQLFKD--NTDIEGVDTVNACYGGTSALFNAISWVESSSWDGRYALVVAGDI-AVYAKG 153          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS2_BLAGE (Hydroxymethylglutaryl-CoA synthase 2 OS=Blattella germanica GN=HMGCS-2 PE=2 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 3.616e-26
Identity = 45/92 (48.91%), Postives = 65/92 (70.65%), Query Frame = 2

Query:  269 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            ++VGI+ +++ FP   V Q  LE +D  S GKYT+GLGQ+ M  C++ ED+ S+ LTAV  L+E+  ID   IG LEVG+ET+++K KS+KT
Sbjct:    6 EDVGIIGIEMIFPSLYVDQAELETYDEVSPGKYTMGLGQDKMGVCTDREDINSLCLTAVDKLMERNNIDYNDIGWLEVGTETILDKVKSVKT 97          

HSP 2 Score: 46.9802 bits (110), Expect = 3.616e-26
Identity = 22/52 (42.31%), Postives = 33/52 (63.46%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHACLRRTGGLFYWGNGVKSISGNGR 680
            +   ++  LMQ+FE  GNTD+EG+D+ +AC R T  LF     ++S S +GR
Sbjct:   91 KVKSVKTVLMQLFEESGNTDVEGIDTINACYRGTAALFNALIWIESSSWDGR 142          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS_SCHPO (Hydroxymethylglutaryl-CoA synthase OS=Schizosaccharomyces pombe GN=hcs1 PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 8.544e-25
Identity = 51/92 (55.43%), Postives = 70/92 (76.09%), Query Frame = 2

Query:  269 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            K++GI  + +Y P   V+Q ALEAHDG S GKYTIGLG   MAF  + ED+ S  LTA++ L+++Y+ID  +IGRLEVG+ET+I+KSKS+K+
Sbjct:    6 KDIGIKGLVLYTPNQYVEQAALEAHDGVSTGKYTIGLGLTKMAFVDDREDIYSFGLTALSQLIKRYQIDISKIGRLEVGTETIIDKSKSVKS 97          

HSP 2 Score: 30.0314 bits (66), Expect = 8.544e-25
Identity = 16/54 (29.63%), Postives = 31/54 (57.41%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHACLRRTGGLFYWGNGVKSISGNGRLG 686
            ++  ++  LMQ+F +  N ++EG+D  +AC      LF   + ++S + +GR G
Sbjct:   91 KSKSVKSVLMQLFGD--NHNVEGIDCVNACYGGVNALFNTIDWIESSAWDGRDG 142          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCSB_DICDI (Hydroxymethylglutaryl-CoA synthase B OS=Dictyostelium discoideum GN=hgsB PE=3 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 2.169e-23
Identity = 53/101 (52.48%), Postives = 75/101 (74.26%), Query Frame = 2

Query:  269 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKTFFDANF*EF 571
            K++GI A+DIYFP T V Q  L+ +D  S GKYTIGLGQ  M+F  + ED++SM++T+V  ++ KY ID + IGRLEVG+ET+I+KSKS+K+   + F E+
Sbjct:    5 KDIGICAIDIYFPQTYVNQSELKKYDKVSNGKYTIGLGQTNMSFVGDREDIVSMAMTSVKMMMSKYSIDYQSIGRLEVGTETIIDKSKSVKSSIMSLFQEY 105          

BLAST of EY727705 vs. ExPASy Swiss-Prot
Match: HMCS_CAEEL (Hydroxymethylglutaryl-CoA synthase OS=Caenorhabditis elegans GN=F25B4.6 PE=2 SV=2)

HSP 1 Score: 101.293 bits (251), Expect = 7.511e-23
Identity = 50/91 (54.95%), Postives = 65/91 (71.43%), Query Frame = 2

Query:  272 NVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVINKSKSIKT 544
            +VGI A+++YFP   V Q  LE  +  S GKYTIGLGQ+ M FCS+ ED++S+SLT    L+E YKI    IG L VG+ET+I+KSKS+KT
Sbjct:   13 DVGIGAIELYFPQNFVDQNDLEKFNNVSSGKYTIGLGQQQMGFCSDNEDIVSISLTVTRKLIETYKISTDSIGCLVVGTETMIDKSKSVKT 103          

HSP 2 Score: 27.7202 bits (60), Expect = 7.511e-23
Identity = 13/30 (43.33%), Postives = 20/30 (66.67%), Query Frame = 3

Query:  525 RANPLRLFLMQIFENFGNTDIEGVDSTHAC 614
            ++  ++  LM +F   GN+DIEGVD  +AC
Sbjct:   97 KSKSVKTALMDLFP--GNSDIEGVDIKNAC 124