EY753292

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1A1_PIG (Alcohol dehydrogenase [NADP+] OS=Sus scrofa GN=AKR1A1 PE=1 SV=2)

HSP 1 Score: 106.686 bits (265), Expect = 1.757e-22
Identity = 52/123 (42.28%), Postives = 79/123 (64.23%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF--NPENLLPLDIP---STWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+DV  AL  TL DL+++Y+DLYL+HWP   ++G   F  N +  +  D      TW+A+EAL   G  RA+G+ NFS++++ D+L +A V PAV QVECHP   Q +L   C+++G+ ++ Y
Sbjct:   88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAY 210          

HSP 2 Score: 85.1149 bits (209), Expect = 5.476e-16
Identity = 41/75 (54.67%), Postives = 53/75 (70.67%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDG-VVKREDLWITSKLW 288
            L+TG KMP +GLGTW+++PG V  A+  A+  GYRHIDCA +Y NE EIG  L +    G  V RE+L++TSKLW
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALTETVGPGKAVPREELFVTSKLW 82          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1A1_PONAB (Alcohol dehydrogenase [NADP+] OS=Pongo abelii GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 3.915e-22
Identity = 51/123 (41.46%), Postives = 79/123 (64.23%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF--NPENLLPLD---IPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+DV  AL  TL DL+++Y+DLYL+HWP   ++G   F  N +  +  D      TW+A+EAL   G  RA+G+ NF+++++ D+L +A V PAV QVECHP   Q +L   C+++G+ ++ Y
Sbjct:   88 PEDVEPALQKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVRALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLAVTAY 210          

HSP 2 Score: 87.4261 bits (215), Expect = 1.103e-16
Identity = 43/75 (57.33%), Postives = 54/75 (72.00%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDG-VVKREDLWITSKLW 288
            L+TG KMP +GLGTW+++PG V  AV  A+  GYRHIDCA +Y NE EIG  LK+    G  V RE+L++TSKLW
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLW 82          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: YDG7_SCHPO (Uncharacterized oxidoreductase C26F1.07 OS=Schizosaccharomyces pombe GN=SPAC26F1.07 PE=2 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 5.113e-22
Identity = 55/128 (42.97%), Postives = 79/128 (61.72%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLL--PLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            C   AP+ VP+AL+ TL+DL++DY+D YLIHWP   K G   F  +   NL+     I  TW+AME L ++GK R IG+ NF+   L  +L++A+V PAV+Q+E HP   Q +     K  G+H++ Y
Sbjct:   88 CNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAY 215          

HSP 2 Score: 81.6481 bits (200), Expect = 6.054e-15
Identity = 39/77 (50.65%), Postives = 54/77 (70.13%), Query Frame = 1

Query:   58 YFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +F L  G+K+P +GLGTW+++P    NAV  A++ GYRHID A +Y NE E+G  +K   E G V R+D+W+TSKLW
Sbjct:   15 HFTLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK---ESG-VPRKDIWVTSKLW 87          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1A1_CRIGR (Alcohol dehydrogenase [NADP+] (Fragment) OS=Cricetulus griseus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 6.678e-22
Identity = 50/123 (40.65%), Postives = 79/123 (64.23%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF--NPENLLPLD---IPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+DV  AL  TL DL+++Y+DLYL+HWP   ++G   F  N +  +  D      TW+A+EAL   G  +A+G+ NF+++++ D+L +A V PAV QVECHP   Q +L   C+++G+ ++ Y
Sbjct:   73 PEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAY 195          

HSP 2 Score: 74.3294 bits (181), Expect = 9.666e-13
Identity = 36/66 (54.55%), Postives = 47/66 (71.21%), Query Frame = 1

Query:   94 VGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDG-VVKREDLWITSKLW 288
            +GLGTW+++PG V  A+  A+  GYRHIDCA +Y NE EIG  LK+    G  V RE+L++TSKLW
Sbjct:    2 IGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLW 67          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1A1_BOVIN (Alcohol dehydrogenase [NADP+] OS=Bos taurus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 6.678e-22
Identity = 51/123 (41.46%), Postives = 78/123 (63.41%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF--NPENLLPLD---IPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+DV  AL  TL DL+++Y+DLYL+HWP   ++G   F  N +  +  D      TWRA+EAL   G  RA+G+ NF+++++ D+L +A V PAV QVECHP   Q +L   C+++ + ++ Y
Sbjct:   88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDSPFPKNADGTIRYDSTHYKETWRALEALVAKGLVRALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARNLEVTAY 210          

HSP 2 Score: 89.3521 bits (220), Expect = 2.904e-17
Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDG-VVKREDLWITSKLW 288
            L+TG KMP +GLGTW++DPG V  A+  A+  GYRHIDCA +Y NE EIG  LK+    G +V RE+L++TSKLW
Sbjct:    8 LHTGQKMPLIGLGTWKSDPGQVKAAIKYALSVGYRHIDCAAIYGNETEIGEALKENVGPGKLVPREELFVTSKLW 82          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 104.375 bits (259), Expect = 8.722e-22
Identity = 47/82 (57.32%), Postives = 62/82 (75.61%), Query Frame = 1

Query:   52 SGYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            + + ELN G KMP++GLGTW++ PG V  AV VAI  GYRHIDCA++Y NEKE+G  L++  ++ VVKR+DL+I SKLW  F
Sbjct:    2 ASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTF 83          

HSP 2 Score: 100.523 bits (249), Expect = 1.259e-20
Identity = 59/144 (40.97%), Postives = 80/144 (55.56%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLLP--LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            Q +F++SK      CT      V  A   TL DL++DY+DLYLIHWP   K G   F  +   N++P   D   TW AME L D G  +AIGV NF+  ++  +L     +  PAVNQ+ECHP   Q+KL  +C  KG+ ++ Y
Sbjct:   71 QDLFIVSKLW----CTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAY 210          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALDR_MOUSE (Aldose reductase OS=Mus musculus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 104.375 bits (259), Expect = 8.722e-22
Identity = 47/82 (57.32%), Postives = 62/82 (75.61%), Query Frame = 1

Query:   52 SGYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            + + ELN G KMP++GLGTW++ PG V  AV VAI  GYRHIDCA++Y NEKE+G  L++  ++ VVKR+DL+I SKLW  F
Sbjct:    2 ASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTF 83          

HSP 2 Score: 101.293 bits (251), Expect = 7.384e-21
Identity = 59/144 (40.97%), Postives = 80/144 (55.56%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLLP--LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            Q +F++SK      CT      V  A   TL DL++DY+DLYLIHWP   K G   F  +   N++P   D   TW AME L D G  + IGV NF+  ++  +L     +  PAVNQ+ECHP   Q+KL  +C SKG+ ++ Y
Sbjct:   71 QDLFIVSKLW----CTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAY 210          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1A1_RAT (Alcohol dehydrogenase [NADP+] OS=Rattus norvegicus GN=Akr1a1 PE=1 SV=2)

HSP 1 Score: 104.375 bits (259), Expect = 8.722e-22
Identity = 50/123 (40.65%), Postives = 79/123 (64.23%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF--NPENLLPLD---IPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+DV  A+  TL DL+++Y+DLYL+HWP   ++G   F  N +  +  D      TW+A+EAL   G  +A+G+ NFS++++ D+L +A V PAV QVECHP   Q +L   C+++G+ ++ Y
Sbjct:   88 PEDVEPAVRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAY 210          

HSP 2 Score: 87.0409 bits (214), Expect = 1.441e-16
Identity = 42/75 (56.00%), Postives = 54/75 (72.00%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDG-VVKREDLWITSKLW 288
            L+TG KMP +GLGTW+++PG V  A+  A+  GYRHIDCA +Y NE EIG  LK+    G  V RE+L++TSKLW
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKLW 82          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALDR_PIG (Aldose reductase OS=Sus scrofa GN=AKR1B1 PE=1 SV=2)

HSP 1 Score: 103.99 bits (258), Expect = 1.139e-21
Identity = 60/144 (41.67%), Postives = 82/144 (56.94%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF---NPENLLP--LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + +F++SK      CTD     V  A   TL+DL++DY+DLYLIHWP   K G   F      N++P   D   TW AME L D G  +AIGV NF+  ++  +L     +  PAVNQ+E HP   Q+KL  +CKSKG+ ++ Y
Sbjct:   71 EDLFIVSKLW----CTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAY 210          

HSP 2 Score: 96.6709 bits (239), Expect = 1.819e-19
Identity = 46/79 (58.23%), Postives = 57/79 (72.15%), Query Frame = 1

Query:   52 SGYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            + +  L TGAKMP +GLGTW++ PG V  AV VAI  GYRHIDCA +Y NE E+G  L++  +  VVKREDL+I SKLW
Sbjct:    2 ASHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQVVKREDLFIVSKLW 80          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1A1_HUMAN (Alcohol dehydrogenase [NADP+] OS=Homo sapiens GN=AKR1A1 PE=1 SV=3)

HSP 1 Score: 103.99 bits (258), Expect = 1.139e-21
Identity = 50/123 (40.65%), Postives = 79/123 (64.23%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF--NPENLLPLD---IPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+DV  AL  TL DL+++Y+DLYL+HWP   ++G   F  N +  +  D      TW+A+EAL   G  +A+G+ NF+++++ D+L +A V PAV QVECHP   Q +L   C+++G+ ++ Y
Sbjct:   88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAY 210          

HSP 2 Score: 87.4261 bits (215), Expect = 1.103e-16
Identity = 43/75 (57.33%), Postives = 54/75 (72.00%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDG-VVKREDLWITSKLW 288
            L+TG KMP +GLGTW+++PG V  AV  A+  GYRHIDCA +Y NE EIG  LK+    G  V RE+L++TSKLW
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLW 82