EY753292

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 1.943e-21
Identity = 59/144 (40.97%), Postives = 82/144 (56.94%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLLPL--DIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIA--RVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + +F++SK    +   DL    V  A   TL DL++DY+DLYLIHWP   K G   F  +   N++P   D   TW AME L D G  +AIGV NF+  ++  +L     +  PAVNQ+ECHP   Q+KL  +C SKG+ ++ Y
Sbjct:   70 EDLFIVSKLWCTYHDKDL----VKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAY 209          

HSP 2 Score: 98.2117 bits (243), Expect = 6.251e-20
Identity = 46/77 (59.74%), Postives = 56/77 (72.73%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            L TGAKMP +GLGTW++ PG V  AV VAI  GYRHIDCA +Y NE E+G  L+   ++ VVKREDL+I SKLW  +
Sbjct:    6 LYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVVKREDLFIVSKLWCTY 82          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1A1_MOUSE (Alcohol dehydrogenase [NADP+] OS=Mus musculus GN=Akr1a1 PE=1 SV=3)

HSP 1 Score: 101.679 bits (252), Expect = 5.653e-21
Identity = 49/123 (39.84%), Postives = 77/123 (62.60%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF--NPENLLPLD---IPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+DV  AL  TL DL+++Y+DLYL+HWP   ++G   F  N +  +  D      TW+A+E L   G  +A+G+ NF+++++ D+L +A V PAV QVECHP   Q +L   C ++G+ ++ Y
Sbjct:   88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAY 210          

HSP 2 Score: 88.5817 bits (218), Expect = 4.953e-17
Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDG-VVKREDLWITSKLW 288
            L+TG KMP +GLGTW+++PG V  A+  A+ AGYRHIDCA +Y NE EIG  LK+    G  V RE+L++TSKLW
Sbjct:    8 LHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLW 82          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 100.908 bits (250), Expect = 9.643e-21
Identity = 59/142 (41.55%), Postives = 82/142 (57.75%), Query Frame = 2

Query:  401 MFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLLPLD--IPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIA--RVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            +F++SK      CT      V  A   TL DL++DY+DLYLIHWP   K G   F  +   N++P D  I  TW AME L D G  +AIG+ NF+  ++  +L     +  PAVNQ+ECHP   Q+KL  +C+SKG+ ++ Y
Sbjct:   73 LFIVSKLW----CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAY 210          

HSP 2 Score: 97.0561 bits (240), Expect = 1.392e-19
Identity = 44/77 (57.14%), Postives = 56/77 (72.73%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            LN GAKMP +GLGTW++ PG V  AV VAI  GYRHIDCA +Y NE E+G  +++   + VVKRE+L+I SKLW  +
Sbjct:    7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTY 83          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1CL_MOUSE (Aldo-keto reductase family 1 member C21 OS=Mus musculus GN=Akr1c21 PE=1 SV=2)

HSP 1 Score: 99.7525 bits (247), Expect = 2.148e-20
Identity = 56/130 (43.08%), Postives = 75/130 (57.69%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPL-----DIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            CT L P+ V  +L+ +LQ L+ DYVDLYLIH+P  +K G   F  +    L     D+ +TW AME   D+G  ++IGV NF+ ++L  +L     +  P  NQVECHP   Q KL  FCKSK + L  Y
Sbjct:   87 CTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAY 216          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 3.664e-20
Identity = 47/80 (58.75%), Postives = 61/80 (76.25%), Query Frame = 1

Query:   61 FELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVL-KKLFEDGVVKREDLWITSKLWFVF 297
            F+L++G K+P VG GTW+A+  +VG AV+VA+ AGYRHIDCA +YLNEKE+G    KK   +  VKRED++ITSKLW  F
Sbjct:    5 FKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKLWNTF 84          

HSP 2 Score: 94.7449 bits (234), Expect = 6.911e-19
Identity = 47/117 (40.17%), Postives = 65/117 (55.56%), Query Frame = 2

Query:  461 VPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP--LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            V  AL+ TL DL + Y+DLYL+HWP   +  S            + I  TW  ME L D+G  ++IG+ NF+ + L ++L  AR+ PA NQVE HP   Q +L  FC    +HL+ Y
Sbjct:   90 VRPALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAY 206          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: A1A1B_DANRE (Alcohol dehydrogenase [NADP+] B OS=Danio rerio GN=akr1a1b PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 3.664e-20
Identity = 50/123 (40.65%), Postives = 76/123 (61.79%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN---LL--PLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P DV  +L  TL+DL+++Y+DLYLIHWP   ++G   F  +    LL   +D   TW AME L   G  RAIG+ NF+++++ D+L +A + P V QVE HP   Q +L + C+ +G+ ++ Y
Sbjct:   87 PDDVEPSLLKTLKDLKLEYLDLYLIHWPYAFQRGDTPFPRKEDGTLLYDDIDYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILSVASIKPTVLQVESHPYLAQVELLSHCRDRGLVMTAY 209          

HSP 2 Score: 87.0409 bits (214), Expect = 1.441e-16
Identity = 40/75 (53.33%), Postives = 58/75 (77.33%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKK-LFEDGVVKREDLWITSKLW 288
            L+TG KMP +GLGTW+++PG+V  AV  A+++GYRHIDCA +Y NE EIG   ++ +  D  ++RED+++TSKLW
Sbjct:    7 LSTGRKMPLLGLGTWKSEPGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKLW 81          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALD1_MOUSE (Aldose reductase-related protein 1 OS=Mus musculus GN=Akr1b7 PE=2 SV=4)

HSP 1 Score: 98.5969 bits (244), Expect = 4.786e-20
Identity = 46/80 (57.50%), Postives = 58/80 (72.50%), Query Frame = 1

Query:   58 YFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            + EL+T AKMP VGLGTW++ PG V  AV  AI AGYRHIDCA +Y NE E+G  +++  ++  VKREDL+I SKLW  F
Sbjct:    4 FVELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKREDLFIVSKLWATF 83          

HSP 2 Score: 88.9669 bits (219), Expect = 3.792e-17
Identity = 46/122 (37.70%), Postives = 68/122 (55.74%), Query Frame = 2

Query:  461 VPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN-----LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            V +A  NTL DL++DY+DLYL+HWP   + G+     +N     L        W AME L D G  +A+G+ NF+  ++  LL     +  P  NQ+E HP   Q+KL  +C+SKG+ ++ Y
Sbjct:   89 VKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAY 210          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C1_MACFU (Aldo-keto reductase family 1 member C1 homolog OS=Macaca fuscata fuscata GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 4.786e-20
Identity = 56/136 (41.18%), Postives = 79/136 (58.09%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            C    P+ V  AL+ +L++L++DYVDLYLIH+P  +K G      E L+P           +D+ +TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP   Q+KL  FCKSK + L  Y
Sbjct:   87 CNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPG------EELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAY 216          

HSP 2 Score: 69.707 bits (169), Expect = 2.381e-11
Identity = 35/78 (44.87%), Postives = 49/78 (62.82%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVD---VAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +LN G  MP +G GT+         A++   +AI+AG+RHID A LY NE+ +G  ++    DG VKRED++ TSKLW
Sbjct:    9 KLNDGHFMPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVKREDIFYTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: PE2R_RABIT (Prostaglandin-E(2) 9-reductase OS=Oryctolagus cuniculus GN=AKR1C5 PE=1 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 6.251e-20
Identity = 59/143 (41.26%), Postives = 83/143 (58.04%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN------LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY--------PHWV 817
            CT   P+ V  +L+++L++L++DYVDLY+IH+P  +K G V   P +         +DI +TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP   Q KL  FCKSKG+ L  Y        P WV
Sbjct:   87 CTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPG-VEIIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWV 228          

HSP 2 Score: 70.4774 bits (171), Expect = 1.396e-11
Identity = 35/80 (43.75%), Postives = 49/80 (61.25%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVD---VAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            L+ G  +P +G GT+  +      A++   +AI AG+RHID A  Y NEKE+G  ++    DG VKRED++ TSKLW  F
Sbjct:   10 LSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKIADGTVKREDIFYTSKLWCTF 89          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALD2_CRIGR (Aldose reductase-related protein 2 OS=Cricetulus griseus GN=AKR1B8 PE=1 SV=3)

HSP 1 Score: 98.2117 bits (243), Expect = 6.251e-20
Identity = 47/79 (59.49%), Postives = 58/79 (73.42%), Query Frame = 1

Query:   52 SGYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            S + EL+T AKMP VGLGTWQ+ PG V  AV VAI AGYRHIDCA  Y NE E+G  +++  ++  V+REDL+I SKLW
Sbjct:    2 STFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKIKEKAVRREDLFIVSKLW 80          

HSP 2 Score: 90.5077 bits (223), Expect = 1.303e-17
Identity = 54/144 (37.50%), Postives = 78/144 (54.17%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLLPLDIP--STWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + +F++SK       T    K + EA   TL DL++DY+DLYLIHWP  ++ G   F  +   N+L   I     W  ME L D G  +A+GV NF+  ++  +L     +  P  NQVECHP   Q+KL  +C SKG+ ++ Y
Sbjct:   71 EDLFIVSKLWP----TCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTNQVECHPYLTQEKLIEYCHSKGITVTAY 210