EY753292

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 8.164e-20
Identity = 58/136 (42.65%), Postives = 77/136 (56.62%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            CT   P+ V   L+ +L+ L++DYVDLYLIH+P  MK G      EN LP           +DI  TW AME   D+G A++IGV NF+ ++L  +L+    +  P  NQVECHP   Q KL  FC+SK + L  Y
Sbjct:   87 CTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPG------ENYLPKDENGKLIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAY 216          

HSP 2 Score: 70.4774 bits (171), Expect = 1.396e-11
Identity = 34/80 (42.50%), Postives = 48/80 (60.00%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTW---QADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            L+ G  +P +G GT+   +        A  +AI AG+RHID A +Y NEKE+G  ++    DG VKRED++ TSK+W  F
Sbjct:   10 LSDGHFIPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVKREDIFYTSKVWCTF 89          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: DDBX_BOVIN (Dihydrodiol dehydrogenase 3 OS=Bos taurus PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 8.164e-20
Identity = 55/129 (42.64%), Postives = 76/129 (58.91%), Query Frame = 2

Query:  440 TDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF-NPENLLPL----DIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            T L P+ V  AL+ +L +L++DYVDLY+IH+P  +K G   F   EN  P+    D+  TW A+E   D+G  ++IGV NF+ K+L  +L     +  P  NQVECHP + Q KL  FCKS  + L  Y
Sbjct:   88 TSLRPELVRPALEKSLNNLQLDYVDLYIIHFPVALKPGETLFPTDENGKPIFDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYFNQSKLLDFCKSHDIVLVAY 216          

HSP 2 Score: 68.9366 bits (167), Expect = 4.061e-11
Identity = 35/78 (44.87%), Postives = 50/78 (64.10%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVDV---AIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +LN G  +P +G GT+         A++V   AI+AG+RHID A LY NE+++G  ++    DG VKRED++ TSKLW
Sbjct:    9 KLNDGHFIPVLGFGTFAPREVPKSEALEVTKFAIEAGFRHIDSAHLYQNEEQVGQAIRSKIADGTVKREDIFYTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALDX_SPOSA (Aldehyde reductase 1 OS=Sporobolomyces salmonicolor GN=ARI PE=1 SV=3)

HSP 1 Score: 97.4413 bits (241), Expect = 1.066e-19
Identity = 54/135 (40.00%), Postives = 76/135 (56.30%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE-----NLLP------------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+ V  ALD+TL++L ++Y+DLYLIHWP       V F PE     NL P            + +  TW+AM  L D+GK +AIGV NF  K +  ++E   V P+VNQ+E HP   Q +L    K+K +H++ Y
Sbjct:   82 PEQVEPALDDTLKELGLEYLDLYLIHWP-------VAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAY 209          

HSP 2 Score: 88.5817 bits (218), Expect = 4.953e-17
Identity = 44/78 (56.41%), Postives = 54/78 (69.23%), Query Frame = 1

Query:   55 GYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            G   LNTGA +  VG GTWQA PG VG  V VAI+ GYRH+D A++Y N+ E+G  +K    +  VKREDL+ITSKLW
Sbjct:    3 GTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK----EAGVKREDLFITSKLW 76          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C1_PONAB (Aldo-keto reductase family 1 member C1 homolog OS=Pongo abelii GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 1.066e-19
Identity = 54/136 (39.71%), Postives = 80/136 (58.82%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            C    P+ V  AL+ +L++L++DYVDLYL+H+P  +K G      E ++P           +D+ +TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP + Q+KL  FCKSK + L  Y
Sbjct:   87 CNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVKPG------EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAY 216          

HSP 2 Score: 68.9366 bits (167), Expect = 4.061e-11
Identity = 37/79 (46.84%), Postives = 51/79 (64.56%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGN----AVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +LN    MP +G GT+ A P V  +    A  +AI+AG+RHID A LY NE+++G  ++    DG VKRED++ TSKLW
Sbjct:    9 KLNDSHFMPVLGFGTY-APPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: GR_BACSU (Glyoxal reductase OS=Bacillus subtilis GN=yvgN PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.392e-19
Identity = 48/112 (42.86%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  470 ALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            A + +L+ L++DY+DLYLIHWP + K                  TWRA+E LY  GK RAIGV NF    L +LL+ A + P VNQVE HP   Q++L  +CK +G+ L  +
Sbjct:   93 AFEKSLERLQLDYLDLYLIHWPGKDK---------------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAW 189          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: CRO_RANTE (Rho crystallin OS=Rana temporaria PE=2 SV=3)

HSP 1 Score: 97.0561 bits (240), Expect = 1.392e-19
Identity = 49/130 (37.69%), Postives = 77/130 (59.23%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            CT  +P+ V + L+ +L+D+ +DY+DL+L+HWP  +K        +   P     +D+ +TW A+EA  D+G  R++GV NF+ ++L  +L     +  P  NQVECH    Q KLH++CKSK + L  Y
Sbjct:   88 CTYFSPEMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCNQVECHVYLNQNKLHSYCKSKDIVLVTY 217          

HSP 2 Score: 70.0922 bits (170), Expect = 1.823e-11
Identity = 39/81 (48.15%), Postives = 48/81 (59.26%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGV----VGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            LN G  MP +GLGT+ A P V       AV +AI  GYRHIDCA +  NE  IG  ++    DG VKRED++ T KLW  +
Sbjct:   11 LNDGNMMPILGLGTY-ASPHVPKSLAEEAVKIAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVKREDIFYTGKLWCTY 90          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C1_MACFA (Aldo-keto reductase family 1 member C1 homolog OS=Macaca fascicularis GN=AKR1C1 PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.392e-19
Identity = 55/136 (40.44%), Postives = 79/136 (58.09%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            C    P+ V  AL+ +L++L++DYVDLYLIH+P  +K G      E L+P           +D+ +TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP   Q+KL  FCKSK + L  +
Sbjct:   87 CNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPG------EELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAF 216          

HSP 2 Score: 69.707 bits (169), Expect = 2.381e-11
Identity = 35/78 (44.87%), Postives = 48/78 (61.54%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTW---QADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +LN G  MP +G GT+   +        A  +AI+AG+RHID A LY NE+ +G  ++    DG VKRED++ TSKLW
Sbjct:    9 KLNDGHFMPVLGFGTYAPAEVPKNKALEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVKREDIFYTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1CL_RAT (Aldo-keto reductase family 1 member C21 OS=Rattus norvegicus GN=Akr1c21 PE=2 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.819e-19
Identity = 55/130 (42.31%), Postives = 78/130 (60.00%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLL--PLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            CT L P+ V  +L+ +L+ L++DYVDLYLIH+P  +K G   F  +    LL   +D+ +TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECH    Q KL  FCK+ G+ L  Y
Sbjct:   87 CTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKPGDENFPVDEHGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFCKTNGIILVAY 216          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: CRO_RANCA (Rho crystallin OS=Rana catesbeiana PE=1 SV=2)

HSP 1 Score: 96.2857 bits (238), Expect = 2.375e-19
Identity = 49/130 (37.69%), Postives = 76/130 (58.46%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            CT  +P  V + L+ +L+D+ +DY+DL+L+HWP  +K        +   P     +D+ +TW A+EA  D+G  R++GV NF+ ++L  +L     +  P  NQVECH    Q KLH++CKSK + L  Y
Sbjct:   88 CTYFSPDMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCNQVECHVYLNQNKLHSYCKSKDIVLVTY 217          

HSP 2 Score: 69.707 bits (169), Expect = 2.381e-11
Identity = 37/80 (46.25%), Postives = 46/80 (57.50%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADP---GVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            LN G  MP +GLGT+ A      +   AV  AI  GYRHIDCA +  NE  IG  ++    DG VKRED++ T KLW  +
Sbjct:   11 LNDGNMMPILGLGTYAAPDVPKSLAEEAVKTAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVKREDIFYTGKLWCTY 90          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C1_HUMAN (Aldo-keto reductase family 1 member C1 OS=Homo sapiens GN=AKR1C1 PE=1 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 2.375e-19
Identity = 54/136 (39.71%), Postives = 80/136 (58.82%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            C    P+ V  AL+ +L++L++DYVDLYLIH+P  +K G      E ++P           +D+ +TW A+E   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP + Q+KL  FCKSK + L  Y
Sbjct:   87 CNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG------EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAY 216          

HSP 2 Score: 70.4774 bits (171), Expect = 1.396e-11
Identity = 35/78 (44.87%), Postives = 49/78 (62.82%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTW---QADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +LN G  MP +G GT+   +        A  +AI+AG+RHID A LY NE+++G  ++    DG VKRED++ TSKLW
Sbjct:    9 KLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLW 86