EY753292

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C2_HUMAN (Aldo-keto reductase family 1 member C2 OS=Homo sapiens GN=AKR1C2 PE=1 SV=3)

HSP 1 Score: 94.3597 bits (233), Expect = 9.026e-19
Identity = 54/131 (41.22%), Postives = 78/131 (59.54%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+ V  AL+ +L++L++DYVDLYLIH+P  +K G      E ++P           +D+ +TW AME   D+G A++IGV NF+ + L  +L     +  P  NQVECHP + Q+KL  FCKSK + L  Y
Sbjct:   92 PELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG------EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAY 216          

HSP 2 Score: 68.9366 bits (167), Expect = 4.061e-11
Identity = 34/78 (43.59%), Postives = 49/78 (62.82%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTW---QADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +LN G  MP +G GT+   +        AV +AI+AG+ HID A +Y NE+++G  ++    DG VKRED++ TSKLW
Sbjct:    9 KLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: YBN4_SCHPO (Uncharacterized oxidoreductase C8E4.04 OS=Schizosaccharomyces pombe GN=SPBC8E4.04 PE=2 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.179e-18
Identity = 51/121 (42.15%), Postives = 73/121 (60.33%), Query Frame = 2

Query:  461 VPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN----LLPLDIP--STWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            VP AL+ TLQDL ++Y+D YLIHWP  +  G     P N    L+  D+P   TW+AME L ++GK R IG+ NF+ + L  +L+IA+V P ++Q+E HP   Q +     K   +H+S Y
Sbjct:   95 VPLALEKTLQDLNLEYIDAYLIHWPFALLSGPEEL-PRNEKGELIYEDVPIEETWQAMEELLETGKVRYIGISNFNNEYLDRVLKIAKVKPTIHQMELHPYLPQTEYLEKHKKLQIHVSAY 214          

HSP 2 Score: 84.7297 bits (208), Expect = 7.152e-16
Identity = 46/85 (54.12%), Postives = 58/85 (68.24%), Query Frame = 1

Query:   34 AEMANESGYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            A+ A E+ YF L  G K+PS+GLGTW++      NAV  A+KAGYRHID A +Y NEKEIG   + + E G V R D+W+TSKLW
Sbjct:    7 AKNAREA-YFTLPNGDKIPSIGLGTWRSGKDETKNAVCAALKAGYRHIDTAHIYGNEKEIG---EGIRESG-VPRTDIWVTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: XYL1_PICST (NAD(P)H-dependent D-xylose reductase OS=Pichia stipitis GN=XYL1 PE=3 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.179e-18
Identity = 56/129 (43.41%), Postives = 77/129 (59.69%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMK------KGSVGF---NPENLLPLDIP--STWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P +V +AL+ TL DL++DYVDL+LIH+P   K      K   GF     +N    D+P   TW+A+E L  +GK R+IGV NF    L DLL  A + P+V QVE HP  QQ +L  F +S+G+ ++ Y
Sbjct:   85 PDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAY 213          

HSP 2 Score: 78.1814 bits (191), Expect = 6.694e-14
Identity = 37/75 (49.33%), Postives = 49/75 (65.33%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +LN+G  MP+VG G W+ D       +  AIK GYR  D A  Y NEK +G  +KK  ++G+VKREDL++TSKLW
Sbjct:    5 KLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEGIVKREDLFLTSKLW 79          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFU (Aldo-keto reductase family 1 member C4 OS=Macaca fuscata fuscata GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.179e-18
Identity = 52/127 (40.94%), Postives = 74/127 (58.27%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN-----LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHL 796
            CT   P+ V  AL+++L+ L++DYVDLYLIH+P  +K G      +         +D+ + W AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP   Q KL  FCKSK + L
Sbjct:   87 CTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVL 213          

HSP 2 Score: 71.633 bits (174), Expect = 6.265e-12
Identity = 39/81 (48.15%), Postives = 52/81 (64.20%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAV----DVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            LN G  MP +G G++ A P V  N V     +AI+AG+RHID A LY NE+++G  ++    DG VKRED++ TSKLW  F
Sbjct:   10 LNDGHFMPVLGFGSY-APPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTF 89          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFA (Aldo-keto reductase family 1 member C4 OS=Macaca fascicularis GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.179e-18
Identity = 52/127 (40.94%), Postives = 74/127 (58.27%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN-----LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHL 796
            CT   P+ V  AL+++L+ L++DYVDLYLIH+P  +K G      +         +D+ + W AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP   Q KL  FCKSK + L
Sbjct:   87 CTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVL 213          

HSP 2 Score: 73.1738 bits (178), Expect = 2.153e-12
Identity = 40/81 (49.38%), Postives = 52/81 (64.20%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAV----DVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            LN G  MP +G GT+ A P V  N V     +AI+AG+RHID A LY NE+++G  ++    DG VKRED++ TSKLW  F
Sbjct:   10 LNDGHFMPVLGFGTY-APPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTF 89          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C3_PONAB (Aldo-keto reductase family 1 member C3 homolog OS=Pongo abelii GN=AKR1C3 PE=2 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 2.011e-18
Identity = 58/144 (40.28%), Postives = 80/144 (55.56%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGYPHWVLPAKGDQKD 844
            P+ V  AL+N+L+  ++DYVDLYLIH P  +K G      E L P           +D+ +TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP + + KL  FCKSK + L  Y      A G Q+D
Sbjct:   92 PELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG------EELSPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAY-----SALGSQRD 224          

HSP 2 Score: 72.4034 bits (176), Expect = 3.673e-12
Identity = 37/81 (45.68%), Postives = 51/81 (62.96%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVDV---AIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            +LN G  MP +G GT+         A++V   AI+AG+RHID A LY NE+++G  ++    DG VKRED++ TSKLW  F
Sbjct:    9 KLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTF 89          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1C3_HUMAN (Aldo-keto reductase family 1 member C3 OS=Homo sapiens GN=AKR1C3 PE=1 SV=3)

HSP 1 Score: 93.2041 bits (230), Expect = 2.011e-18
Identity = 58/144 (40.28%), Postives = 80/144 (55.56%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGYPHWVLPAKGDQKD 844
            P+ V  AL+N+L+  ++DYVDLYLIH P  +K G      E L P           +D+ +TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECHP + + KL  FCKSK + L  Y      A G Q+D
Sbjct:   92 PELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG------EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAY-----SALGSQRD 224          

HSP 2 Score: 72.4034 bits (176), Expect = 3.673e-12
Identity = 37/81 (45.68%), Postives = 51/81 (62.96%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVDV---AIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            +LN G  MP +G GT+         A++V   AI+AG+RHID A LY NE+++G  ++    DG VKRED++ TSKLW  F
Sbjct:    9 KLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTF 89          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: GCY_YEAST (Protein GCY OS=Saccharomyces cerevisiae GN=GCY1 PE=1 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 2.626e-18
Identity = 54/127 (42.52%), Postives = 72/127 (56.69%), Query Frame = 2

Query:  470 ALDNTLQDLRIDYVDLYLIHWPARMKKG--------SVGFNPENLLPLDIPS-----TWRAMEALYDSGKARAIGVCNFSTKKLGDLL--EIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            ALD +L+ L +DYVDLYL+HWPAR+           SV    +    +DI +     TW  M+ L  +GK +A+GV NFS   L DLL  +  ++ PA NQVE HP   Q +L  FCKSKG+ +  Y
Sbjct:   93 ALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAY 219          

HSP 2 Score: 76.6406 bits (187), Expect = 1.948e-13
Identity = 37/85 (43.53%), Postives = 54/85 (63.53%), Query Frame = 1

Query:   34 AEMANESGYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            A + + +    LNTGA++P +GLGTWQ+       AV  A+K GYRHID A +Y NE ++G  +K    D  V RE++++T+KLW
Sbjct:    3 ATLHDSTKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK----DSGVPREEIFVTTKLW 83          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AKCL2_PIG (1,5-anhydro-D-fructose reductase OS=Sus scrofa GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 92.8189 bits (229), Expect = 2.626e-18
Identity = 56/144 (38.89%), Postives = 77/144 (53.47%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPL-----DIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIA--RVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + +F++SK      CT      V  A   +L+ L++ Y+DLYLIHWP   K G V    +    +     D   TW AME L   G  RAIGV NF+ ++L  LL     RV P  NQ+ECHP   Q+KL +FC+S+ V ++ Y
Sbjct:   62 EDLFIVSKLW----CTCHKKSLVKSACTRSLKALKLQYLDLYLIHWPMGFKPGEVDLPVDRSGMIVASNTDFLDTWEAMEDLVIEGLVRAIGVSNFNHEQLERLLNKPNLRVKPVTNQIECHPYLTQKKLISFCQSRNVSVTAY 201          

HSP 2 Score: 90.5077 bits (223), Expect = 1.303e-17
Identity = 42/69 (60.87%), Postives = 51/69 (73.91%), Query Frame = 1

Query:   82 KMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            K+P +GLGTWQA PG V  AV VAI  GYRH DCA LY NE E+G  ++   ++GVV+REDL+I SKLW
Sbjct:    3 KIPVLGLGTWQAAPGEVTEAVKVAIDTGYRHFDCAYLYHNENEVGVGIQAKIDEGVVRREDLFIVSKLW 71          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AKCL2_MOUSE (1,5-anhydro-D-fructose reductase OS=Mus musculus GN=Akr1e2 PE=1 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 2.626e-18
Identity = 61/150 (40.67%), Postives = 79/150 (52.67%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPLD-----IPS------TWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + +FV+SK      CT      V  A  NTL+ L +DY+DLYLIHWP   K G      E  +PLD     IPS      TW AME L   G  + +GV NF+ ++L  LL+    RV P  NQ+ECHP   Q+KL  FC  + V ++ Y
Sbjct:   62 EDLFVVSKLW----CTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPG------EKDIPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNVSVTAY 201          

HSP 2 Score: 90.5077 bits (223), Expect = 1.303e-17
Identity = 40/68 (58.82%), Postives = 52/68 (76.47%), Query Frame = 1

Query:   85 MPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +P+VGLGTW+A PG V +AV +AI  GYRH DCA LY NE E+G  + +  ++GVVKREDL++ SKLW
Sbjct:    4 IPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKREDLFVVSKLW 71