EY753292

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALD2_MOUSE (Aldose reductase-related protein 2 OS=Mus musculus GN=Akr1b8 PE=1 SV=2)

HSP 1 Score: 92.0485 bits (227), Expect = 4.479e-18
Identity = 43/77 (55.84%), Postives = 55/77 (71.43%), Query Frame = 1

Query:   58 YFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            + EL+T AKMP VGLGTW++ P  V  AV  AI AGYRHIDCA  Y NE E+G  +++  ++  V+REDL+I SKLW
Sbjct:    4 FVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQREDLFIVSKLW 80          

HSP 2 Score: 90.1225 bits (222), Expect = 1.702e-17
Identity = 53/144 (36.81%), Postives = 77/144 (53.47%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPLDIPST-----WRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + +F++SK       T    K + EA   TL DL++DY+DLYLIHWP  ++ G   F  ++   +    T     W  ME L D G  +A+GV NF+  ++  LL     +  P  NQVECHP   Q+KL  +C SKG+ ++ Y
Sbjct:   71 EDLFIVSKLWP----TCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAY 210          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AKCL2_RAT (1,5-anhydro-D-fructose reductase OS=Rattus norvegicus GN=Akr1e2 PE=2 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 4.479e-18
Identity = 41/72 (56.94%), Postives = 55/72 (76.39%), Query Frame = 1

Query:   82 KMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            ++P+VGLGTW+A PG V +AV VAI  GYRH DCA LY NE E+G  +K+  ++GVVKR++L+I SKLW  +
Sbjct:    3 QIPTVGLGTWKASPGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIKEGVVKRDELFIVSKLWCTY 74          

HSP 2 Score: 88.5817 bits (218), Expect = 4.953e-17
Identity = 58/148 (39.19%), Postives = 76/148 (51.35%), Query Frame = 2

Query:  401 MFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPLD-----IPS------TWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            +F++SK      CT      V  A  NTL+ L +DY+DLYLIHWP   K G      +  +PLD     IPS      TW AME L   G  + IGV NF+ ++L  LL     R+ P  NQ+ECHP   Q+ L  FC  + V ++ Y
Sbjct:   64 LFIVSKLW----CTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKPG------DKDIPLDRSGKVIPSHTSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHGRNVSVTAY 201          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALDR_ENCCU (Aldose reductase OS=Encephalitozoon cuniculi GN=ECU01_0970 PE=1 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 7.641e-18
Identity = 45/79 (56.96%), Postives = 59/79 (74.68%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTW-QADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            +LN G ++P+VGLGTW   D  V+  A+  A+  GYRHID A +Y NEK IG +LKKLF++GVV+R+DL+ITSKLW  F
Sbjct:    7 KLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEGVVQRKDLFITSKLWNTF 85          

HSP 2 Score: 87.8113 bits (216), Expect = 8.448e-17
Identity = 51/141 (36.17%), Postives = 71/141 (50.35%), Query Frame = 2

Query:  401 MFVLSK-FVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGF-----NPENLLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            +F+ SK +   H C +       + L  +L DL++DYVDLYLIHWP        G         N+   D    W+ MEAL D G A++IG+ NF       +L   R+ PA  Q+E HP   Q++L  F KSKG+ +  Y
Sbjct:   75 LFITSKLWNTFHGCPE-------DGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISY 208          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1CN_HORSE (Aldo-keto reductase family 1 member C23 OS=Equus caballus GN=AKR1C23 PE=1 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 9.979e-18
Identity = 53/140 (37.86%), Postives = 77/140 (55.00%), Query Frame = 2

Query:  440 TDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN-----LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY-------PHWV 817
            T L  + V  AL+ +L++L++DYVDLY+IH+P  +K G      +         +D+ +TW AME   D+G  ++IGV NF+ ++L  +L     +  P  NQVECHP   Q KL  FCKSK + L  Y        HW+
Sbjct:   88 TSLRLQLVRPALEKSLKNLQLDYVDLYIIHFPVAVKPGEEHLPQDEQGRMIFDTVDLCATWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKHKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAYSALGSQREHWI 227          

HSP 2 Score: 76.6406 bits (187), Expect = 1.948e-13
Identity = 38/78 (48.72%), Postives = 51/78 (65.38%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVDV---AIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            ELN G  + ++G GT+  +      AV+    AI AG+RHIDCA LY NEKE+G  ++   +DG VKRED++ TSKLW
Sbjct:    9 ELNDGHFIHALGFGTYAPNEVPKSKAVEATKSAIDAGFRHIDCAHLYDNEKEVGLAIRSKIQDGTVKREDIFCTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.303e-17
Identity = 43/77 (55.84%), Postives = 61/77 (79.22%), Query Frame = 1

Query:   61 FELNTGAKMPSVGLGTWQAD-PGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            F+LN G ++PS+GLGT+ ++ PG VG+A++ A+K GYRHID A  Y NEK IG  LK++F++G +KRED++ TSKLW
Sbjct:   17 FKLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIKREDIFYTSKLW 93          

HSP 2 Score: 88.5817 bits (218), Expect = 4.953e-17
Identity = 48/118 (40.68%), Postives = 65/118 (55.08%), Query Frame = 2

Query:  482 TLQDLRIDYVDLYLIHWPARMKKGS-VGFNPENL---------LPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            T++DL I Y+DLYLIHWP   +  + +G   E L          P+ I  TW+ ME L + G  ++IGV NF+ + L DLL  A++ P VNQVE HP   Q KL  +C    + L  Y
Sbjct:  109 TIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAY 226          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: YTBE_BACSU (Uncharacterized oxidoreductase ytbE OS=Bacillus subtilis GN=ytbE PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.702e-17
Identity = 44/121 (36.36%), Postives = 65/121 (53.72%), Query Frame = 2

Query:  443 DLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            DL  ++   A + +L  L +DY+DLYLIHWP   K                   WRA+E LY  G+ +AIGV NF    L DL+  A + P +NQVE HP   Q++L  +C+++G+ +  +
Sbjct:   88 DLGYEETLAAFETSLSKLGLDYLDLYLIHWPVEGK---------------YKEAWRALETLYKEGRIKAIGVSNFQIHHLEDLMTAAEIKPMINQVEFHPRLTQKELIRYCQNQGIQMEAW 193          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: XYL1_PACTA (NAD(P)H-dependent D-xylose reductase OS=Pachysolen tannophilus GN=XYL1 PE=1 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 2.223e-17
Identity = 53/133 (39.85%), Postives = 77/133 (57.89%), Query Frame = 2

Query:  449 APKDVPEALDNTLQDLRIDYVDLYLIHWPARMK------KGSVGF---NPENLLPLDIP--STWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGYPHW 814
            A ++V +AL  +L D  +DY DLYL+H+P   K      K   GF   + +  +  D+P   TWRAME L D G  ++IGV N S   L DL++ AR+ PA  Q+E HP  QQ KL  + + KG+ ++GY ++
Sbjct:   84 AKENVKKALMKSLSDFNLDYFDLYLMHFPISFKFVPFEEKYPPGFYCGDGDKFIYEDVPIIETWRAMENLVDEGLVKSIGVSNVSGGLLEDLIKAARIKPASLQIEHHPYLQQNKLVEYAQLKGIVVTGYSNF 216          

HSP 2 Score: 80.1073 bits (196), Expect = 1.761e-14
Identity = 40/80 (50.00%), Postives = 55/80 (68.75%), Query Frame = 1

Query:   58 YFELNTGAKMPSVGLGTWQADPGVVGNAVDV---AIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            Y+ LN G K+P++G+G W+ +     NA D+   AIK GYR  DCA  Y NEKE+G  + +  +DG+VKR+DL+ITSKLW
Sbjct:    5 YYTLNNGRKIPAIGMGCWKLE-----NAADMVYAAIKEGYRLFDCACDYGNEKEVGEGINRAIKDGLVKRKDLFITSKLW 79          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: ALRB_DICDI (Aldose reductase B OS=Dictyostelium discoideum GN=alrB PE=3 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 2.223e-17
Identity = 46/120 (38.33%), Postives = 64/120 (53.33%), Query Frame = 2

Query:  476 DNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN----------LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + TL+DL ++Y+DLYLIHWP   +                    L  + I  TW+ ME L + G  ++IGV NF+ + L DLL  A++ PA+NQVE HP   Q  L  FC   G+ L+ Y
Sbjct:   99 EKTLEDLGLEYLDLYLIHWPIAFENADPSGTTTQPLRDSDGEPVLAAVSIRETWQEMEKLVEYGLVKSIGVSNFNVQNLVDLLTYAKIKPAINQVEVHPYLSQPNLKYFCDRYGIVLTAY 218          

HSP 2 Score: 86.6557 bits (213), Expect = 1.882e-16
Identity = 44/85 (51.76%), Postives = 60/85 (70.59%), Query Frame = 1

Query:   40 MANESGYFELNTGAK-MPSVGLGTWQ-ADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            M+     F+LN     +P +GLGT+  A  G VG+AV VA+K+GYRHID A +Y+NEKEIG  LK++F +G +KRED++  SKLW
Sbjct:    1 MSQPQNTFKLNDDIHHIPMIGLGTYNGAKVGEVGDAVKVALKSGYRHIDGAAIYMNEKEIGHALKEVFAEGEIKREDIFYVSKLW 85          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: YPR1_YEAST (Putative reductase 1 OS=Saccharomyces cerevisiae GN=YPR1 PE=1 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 4.953e-17
Identity = 51/132 (38.64%), Postives = 72/132 (54.55%), Query Frame = 2

Query:  455 KDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP------LDIPS-------TWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIA--RVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            +D   AL+ +L+ L +DYVDLYL+HWP  +K   V       +P      +DI +       TW  M+ L  +GK +A+GV NFS   + +LLE    +V PA NQ+E HP   Q +L  FCK KG+ +  Y
Sbjct:   88 RDPEAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAY 219          

HSP 2 Score: 80.8777 bits (198), Expect = 1.033e-14
Identity = 40/85 (47.06%), Postives = 57/85 (67.06%), Query Frame = 1

Query:   34 AEMANESGYFELNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            A + N S   +LNTGA +P +G GTW++      ++V  A+KAGYRHID A +YLNE+E+G  +K    D  V RE+++IT+KLW
Sbjct:    3 ATLKNSSATLKLNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIK----DSGVPREEIFITTKLW 83          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: XYL1_KLULA (NAD(P)H-dependent D-xylose reductase OS=Kluyveromyces lactis GN=XYL1 PE=3 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 4.953e-17
Identity = 49/135 (36.30%), Postives = 72/135 (53.33%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKK-----------------GSVGFNPENLLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P +VP AL+ TL DL++DYVD++ IH+P   K                   + G   E  +PL    TWRA+E L D GK +++G+ NFS   + DLL  AR+ P   Q+E HP   Q++L  + K+ G+ +  Y
Sbjct:   89 PDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQVPL--LDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAY 221          

HSP 2 Score: 75.485 bits (184), Expect = 4.339e-13
Identity = 38/77 (49.35%), Postives = 49/77 (63.64%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLWFVF 297
            LN G KMP VGLG W+    V  + +  AIK GYR  D A+ Y NEKE+G  + +  ++G+VKREDL + SKLW  F
Sbjct:   10 LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVKREDLVVVSKLWNSF 86