EY685218

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: SMUF2_HUMAN (E3 ubiquitin-protein ligase SMURF2 OS=Homo sapiens GN=SMURF2 PE=1 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 1.209e-43
Identity = 89/202 (44.06%), Postives = 129/202 (63.86%), Query Frame = 3

Query:    6 LLQNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            L  +L W+LENDI+ VLD TF ++ +          ++  +EL P G++I V EENK + V L    R    I  Q  A  +GF E+IP  L+  F++KELEL+I GL  ID++D + NT     +  S +++WFW+ V+ F +E +ARLLQFVTG+S+VPL+GF ALQG +G + F IH+     ++LP AHTCFN++D+P
Sbjct:  529 LHNSLVWILENDITGVLDHTFCVEHNAY-------GEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRLKHCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIP 723          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: NEDD4_MOUSE (E3 ubiquitin-protein ligase NEDD4 OS=Mus musculus GN=Nedd4 PE=1 SV=3)

HSP 1 Score: 175.637 bits (444), Expect = 3.519e-43
Identity = 98/200 (49.00%), Postives = 132/200 (66.00%), Query Frame = 3

Query:   15 NLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEY-SGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +L+W+LEND ++ LDL F ID   E+L      Q   +EL  GG  I VT +NK + + LV + R    I+ Q+ AF EGF ELIP +LI IF++ ELELL+ GL D+D++D R +T+Y +GYS    VI WFW+ V     E + RLLQFVTGTS+VP+ GF+ L G +G Q F + + +G+ D LP AHTCFN+LDLP
Sbjct:  671 SLRWILENDPTE-LDLRFIID---EELF----GQTHQHELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ-WGTPDKLPRAHTCFNRLDLP 861          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: SMUF2_DANRE (E3 ubiquitin-protein ligase SMURF2 OS=Danio rerio GN=smurf2 PE=2 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 4.596e-43
Identity = 85/202 (42.08%), Postives = 130/202 (64.36%), Query Frame = 3

Query:    6 LLQNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            L  +L W+L+NDI+ VLD TF ++ +          ++  +EL P G++I VT++ K + V L    R    I  Q  A  +GF E+IP  L+  F++KELEL++ GL  ID++D ++NT     +  S +++WFW  V+ + +E +ARLLQFVTG+S+VPL+GF ALQG +G + F IH+   S ++LP AHTCFN++D+P
Sbjct:  546 LHNSLVWILDNDITGVLDHTFCVEHNAY-------GEIIQHELKPNGKSIPVTQDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKELELIVCGLGKIDINDWKSNTRLKHCTPDSNIVKWFWRAVESYDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDASTNNLPKAHTCFNRIDIP 740          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: NEDD4_RAT (E3 ubiquitin-protein ligase NEDD4 OS=Rattus norvegicus GN=Nedd4 PE=1 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 4.596e-43
Identity = 97/200 (48.50%), Postives = 132/200 (66.00%), Query Frame = 3

Query:   15 NLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEY-SGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +L+W+LEND ++ LDL F ID   E+L      Q   +EL  GG  + VT +NK + + LV + R    I+ Q+ AF EGF ELIP +LI IF++ ELELL+ GL D+D++D R +T+Y +GYS    VI WFW+ V     E + RLLQFVTGTS+VP+ GF+ L G +G Q F + + +G+ D LP AHTCFN+LDLP
Sbjct:  671 SLRWILENDPTE-LDLRFIID---EELF----GQTHQHELKTGGSEVVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ-WGTPDKLPRAHTCFNRLDLP 861          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: PUB2_SCHPO (E3 ubiquitin-protein ligase pub2 OS=Schizosaccharomyces pombe GN=pub2 PE=1 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 2.979e-42
Identity = 84/200 (42.00%), Postives = 121/200 (60.50%), Query Frame = 3

Query:   12 QNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            ++LKW+  ND+ + L L FS++ +          +    +LIP GRNI V  +NK   +  + EH+L T+   Q NA   G  ELIP  ++ IFN+ EL+ L++G  DID+ D +  T+Y  Y+    ++ WFWE++  +S E KA+LLQF TGTS++PL GF  + G  G +KF I K  G I  LP AHTCFN+LD+P
Sbjct:  455 ESLKWIKNNDVDESLCLNFSVEENRF-------GESVTVDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQFNALKGGLNELIPDSVLQIFNENELDTLLNGKRDIDVQDWKRFTDYRSYTETDDIVIWFWELLSEWSPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTIEKV-GHISQLPKAHTCFNRLDIP 646          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: SMUF1_DROME (E3 ubiquitin-protein ligase Smurf1 OS=Drosophila melanogaster GN=lack PE=1 SV=3)

HSP 1 Score: 168.703 bits (426), Expect = 4.301e-41
Identity = 91/206 (44.17%), Postives = 132/206 (64.08%), Query Frame = 3

Query:    6 LLQNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGS---QKFQIH-KAYGSIDHLPSAHTCFNQLDLP 611
            L ++L WMLE++IS +++ TFS++ +    ++        +EL PGG +I VTEENK + V L   +R    I  Q  A  +GF ELIP  L+  F+++ELEL+I G+  ID++D R NT     +  +  + WFW+VV+ +S E +ARLLQFVTG+S+VPL+GF ALQG +G+   + F IH  A     +LP AHTCFN++DLP
Sbjct:  838 LHRSLTWMLESNISGIIESTFSVENNSFGALVV-------HELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPFDERELELVIGGISSIDVNDWRNNTRLKHCTNETTQVLWFWQVVESYSSEMRARLLQFVTGSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQNLPKAHTCFNRIDLP 1036          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: ITCH_MOUSE (E3 ubiquitin-protein ligase Itchy OS=Mus musculus GN=Itch PE=1 SV=2)

HSP 1 Score: 165.622 bits (418), Expect = 3.641e-40
Identity = 89/200 (44.50%), Postives = 128/200 (64.00%), Query Frame = 3

Query:   15 NLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +L W+ EN+I +  L++ FS+D    K IL E   +  ++L P G NI VTEENK + + +VAE RL+  +  Q  AF EGF E++P + +  F+ KELE+L+ G+ +IDL+D + +  Y  Y+  S  I WFW+ V+    E + RLLQFVTGT ++P+ GF+ L G +G QKF I K  G  + LP +HTCFN+LDLP
Sbjct:  648 SLIWVKENNIEECGLEMYFSVD----KEILGE---IKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKV-GKENWLPRSHTCFNRLDLP 839          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: ITCH_HUMAN (E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens GN=ITCH PE=1 SV=2)

HSP 1 Score: 165.622 bits (418), Expect = 3.641e-40
Identity = 89/200 (44.50%), Postives = 128/200 (64.00%), Query Frame = 3

Query:   15 NLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +L W+ EN+I +  L++ FS+D    K IL E   +  ++L P G NI VTEENK + + +VAE RL+  +  Q  AF EGF E++P + +  F+ KELE+L+ G+ +IDL+D + +  Y  Y+  S  I WFW+ V+    E + RLLQFVTGT ++P+ GF+ L G +G QKF I K  G  + LP +HTCFN+LDLP
Sbjct:  687 SLIWVKENNIEECDLEMYFSVD----KEILGE---IKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKV-GKENWLPRSHTCFNRLDLP 878          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: WWP2_MOUSE (NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Mus musculus GN=Wwp2 PE=2 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 1.384e-39
Identity = 88/200 (44.00%), Postives = 128/200 (64.00%), Query Frame = 3

Query:   15 NLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            ++ W+ EN++ +  L+L F  D +    IL    +VT +EL  GG NI+VTEENK + + L+ + R T  +  Q  AFL+GF E+ P E +  F++KELEL++ G+ +ID+ D + N  Y  Y+ +S  IQWFW+VV+    E + RLLQFVTGT ++P+ GF+ L G +G QKF I +  G    LP +HTCFN+LDLP
Sbjct:  654 SIVWIKENNLEECGLELFFIQDME----IL---GKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRV-GKETWLPRSHTCFNRLDLP 845          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: SUDX_DROME (E3 ubiquitin-protein ligase Su(dx) OS=Drosophila melanogaster GN=Su(dx) PE=1 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 1.384e-39
Identity = 85/200 (42.50%), Postives = 125/200 (62.50%), Query Frame = 3

Query:   15 NLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +L W+ +N+I +  L+L FS+D +          Q+  +EL   G   +VTEENK + + L+ E R+T  I  Q   FLEGF E++P E +  F+++ELEL++ G+ D+D++D + NT Y  Y+  S  + WFW+ V+    E +ARLLQFVTGT +VP+ GF+ L G +G Q+F I K  G    LP +HTCFN+LDLP
Sbjct:  733 SLIWVKDNNIDECGLELWFSVDFEV-------LGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKV-GKETWLPRSHTCFNRLDLP 924