EY684362

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: DYR1A_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Mus musculus GN=Dyrk1a PE=1 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 8.672e-28
Identity = 85/237 (35.86%), Postives = 128/237 (54.01%), Query Frame = 1

Query:   28 RYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFM--HDLCMIHTDLKPENVLLVSSE--YIKVPDYKSSSHTPKDFFLL*KNAKSQVLFKVD*FLAAQLYERPDQNYIVSHPNFIRAPGSPSFGLGGTYPMG*N-GKVGCILWEFGRGEALF 720
            RY+I S +G+G+FGQV++ +DR  +E VAIKI++  K +   A IE+ +L+ + KHD +     V ++  F +RNH+C+VFE L  +LYD LR  N+R   ++L R+ A+Q+   + F+   +L +IH DLKPEN+LL + +   IK+ D+ SS                         L  ++Y+     YI S   F R   SP   LG  Y +  +   +GCIL E   GE LF
Sbjct:  158 RYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ-----------------------LGQRIYQ-----YIQS--RFYR---SPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLF 361          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: DYR1A_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2)

HSP 1 Score: 124.405 bits (311), Expect = 8.672e-28
Identity = 85/237 (35.86%), Postives = 128/237 (54.01%), Query Frame = 1

Query:   28 RYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFM--HDLCMIHTDLKPENVLLVSSE--YIKVPDYKSSSHTPKDFFLL*KNAKSQVLFKVD*FLAAQLYERPDQNYIVSHPNFIRAPGSPSFGLGGTYPMG*N-GKVGCILWEFGRGEALF 720
            RY+I S +G+G+FGQV++ +DR  +E VAIKI++  K +   A IE+ +L+ + KHD +     V ++  F +RNH+C+VFE L  +LYD LR  N+R   ++L R+ A+Q+   + F+   +L +IH DLKPEN+LL + +   IK+ D+ SS                         L  ++Y+     YI S   F R   SP   LG  Y +  +   +GCIL E   GE LF
Sbjct:  158 RYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ-----------------------LGQRIYQ-----YIQS--RFYR---SPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLF 361          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: HIPK3_HUMAN (Homeodomain-interacting protein kinase 3 OS=Homo sapiens GN=HIPK3 PE=1 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 1.479e-27
Identity = 60/162 (37.04%), Postives = 96/162 (59.26%), Query Frame = 1

Query:   16 NLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLLV----SSEYIKVPDYKSSSHTPK 489
            ++ + Y++   +G GTFGQV++CW R   E+VAIKI++    Y     IE+ +L +L+  +      V+    F +RNH C+VFE L  +LYDFL++N +   P+ ++R I +Q+   +  +  L +IH DLKPEN++LV        +KV D+ S+SH  K
Sbjct:  192 SMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSK 353          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: HIPK3_MOUSE (Homeodomain-interacting protein kinase 3 OS=Mus musculus GN=Hipk3 PE=1 SV=2)

HSP 1 Score: 123.25 bits (308), Expect = 1.932e-27
Identity = 59/162 (36.42%), Postives = 96/162 (59.26%), Query Frame = 1

Query:   16 NLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLLV----SSEYIKVPDYKSSSHTPK 489
            ++ + Y++   +G GTFGQV++CW R   E+VAIKI++    Y     IE+ +L +L+  +      V+    F +RNH C+VFE L  +LYDFL++N +   P+ ++R + +Q+   +  +  L +IH DLKPEN++LV        +KV D+ S+SH  K
Sbjct:  192 SMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSK 353          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: HIPK3_RAT (Homeodomain-interacting protein kinase 3 OS=Rattus norvegicus GN=Hipk3 PE=1 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 2.523e-27
Identity = 59/162 (36.42%), Postives = 96/162 (59.26%), Query Frame = 1

Query:   16 NLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLLV----SSEYIKVPDYKSSSHTPK 489
            ++ + Y++   +G GTFGQV++CW R   E+VAIKI++    Y     IE+ +L +L+  +      V+    F +RNH C+VFE L  +LYDFL++N +   P+ ++R + +Q+   +  +  L +IH DLKPEN++LV        +KV D+ S+SH  K
Sbjct:  192 SVKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSK 353          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: DYR1B_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Mus musculus GN=Dyrk1b PE=1 SV=3)

HSP 1 Score: 122.479 bits (306), Expect = 3.295e-27
Identity = 83/237 (35.02%), Postives = 130/237 (54.85%), Query Frame = 1

Query:   28 RYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFM--HDLCMIHTDLKPENVLLVSSE--YIKVPDYKSSSHTPKDFFLL*KNAKSQVLFKVD*FLAAQLYERPDQNYIVSHPNFIRAPGSPSFGLGGTYPMG*N-GKVGCILWEFGRGEALF 720
            RY+I S +G+G+FGQV++ +D + +E+VAIKI++  K +   A IE+ +L+ + +HD +     V ++  F +RNH+C+VFE L  +LYD LR  ++R   ++L R++A+QL   + F+   +L +IH DLKPEN+LL + +   IK+ D+ SS                         L  ++Y+     YI S   F R   SP   LG  Y +  +   +GCIL E   GE LF
Sbjct:  110 RYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ-----------------------LGQRIYQ-----YIQS--RFYR---SPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLF 313          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: DYR1B_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Homo sapiens GN=DYRK1B PE=1 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 3.295e-27
Identity = 83/237 (35.02%), Postives = 130/237 (54.85%), Query Frame = 1

Query:   28 RYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFM--HDLCMIHTDLKPENVLLVSSE--YIKVPDYKSSSHTPKDFFLL*KNAKSQVLFKVD*FLAAQLYERPDQNYIVSHPNFIRAPGSPSFGLGGTYPMG*N-GKVGCILWEFGRGEALF 720
            RY+I S +G+G+FGQV++ +D + +E+VAIKI++  K +   A IE+ +L+ + +HD +     V ++  F +RNH+C+VFE L  +LYD LR  ++R   ++L R++A+QL   + F+   +L +IH DLKPEN+LL + +   IK+ D+ SS                         L  ++Y+     YI S   F R   SP   LG  Y +  +   +GCIL E   GE LF
Sbjct:  110 RYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ-----------------------LGQRIYQ-----YIQS--RFYR---SPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLF 313          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: PPK5_SCHPO (Serine/threonine-protein kinase ppk5 OS=Schizosaccharomyces pombe GN=ppk5 PE=1 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 7.341e-27
Identity = 61/156 (39.10%), Postives = 102/156 (65.38%), Query Frame = 1

Query:   16 NLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGG-NRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLLVS--SEYIKVPDYKSS 474
            +L  RY+I   +G+G+FGQVL+C D +R ++VAIK+++  +K+    ++E+ +L++L + D    N  ++  + FD+R H+CIV E LGS+L+D +R+NNY+  P+ +V+  A Q L+ +  +    +IH DLKPEN+LL       IK+ D+ SS
Sbjct:  513 HLLYRYEIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCEADPADKNNVIRYLSHFDFRGHLCIVTELLGSNLFDVIRENNYKGLPLIVVKSFALQGLQALRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSS 668          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: DYRK2_CHICK (Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Gallus gallus GN=DYRK2 PE=2 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 9.588e-27
Identity = 60/158 (37.97%), Postives = 99/158 (62.66%), Query Frame = 1

Query:   16 NLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGN-RCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLLVSS--EYIKVPDYKSSSH 480
            ++  RY++   +G+G+FGQV++ +D +  + VA+K+VR  K++   A  EI +L+ L K DK  N   + +   F +R+HIC+ FE L  +LY+ ++KN ++ F + LVR+ A  +L+C+  +H   +IH DLKPEN+LL       IKV D+ SS +
Sbjct:  142 HIAYRYEVLKVIGKGSFGQVVKAYDHKMHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNNMNVIHMLENFTFRSHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCY 299          

BLAST of EY684362 vs. ExPASy Swiss-Prot
Match: DYRK2_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Mus musculus GN=Dyrk2 PE=2 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 2.136e-26
Identity = 60/154 (38.96%), Postives = 96/154 (62.34%), Query Frame = 1

Query:   28 RYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGN-RCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLLVSS--EYIKVPDYKSSSH 480
            RY++   +G+G+FGQV++ +D +  + VA+K+VR  K++   A  EI +L+ L K DK      + +   F +RNHIC+ FE L  +LY+ ++KN ++ F + LVR+ A  +L+C+  +H   +IH DLKPEN+LL       IKV D+ SS +
Sbjct:  219 RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSSIKVIDFGSSCY 372