EY680325

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL1_SCHPO (Cullin-1 OS=Schizosaccharomyces pombe GN=cul1 PE=1 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 4.321e-32
Identity = 85/246 (34.55%), Postives = 129/246 (52.44%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSRV-NALESLRQALAMYIRRTGHGIV----------MDEEKDKDMVSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLINLR------QNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKVTVG 689
            F+E T  FYA E  +Y+    + DYLK  EIRL EE E   LYL  ST KPL+   E  L+ +H   +L   F  ++D + +ED+ RMY L SR  N L+ LRQ    +++R+G   V           D +  + M   L  +KAS + +   +F  +  F  ++  AF  L+N         +R  EL+AK+ D  LR  NK    +++E  L  ++++FR+++ KDVF+ FY K L K++  G
Sbjct:  229 FIENTKNFYAKESSEYLASHSITDYLKKAEIRLAEEEELVRLYLHESTLKPLLEATEDVLIAQH-EEVLHNDFARMLDQNCSEDIIRMYRLMSRTPNGLQPLRQTFEEFVKRSGFAAVAKIVPQVGGEADVDPKEYMEMLLSTYKASKELV-NTAFHGDTDFTKSLDTAFRELVNRNVVCQRSSSRSPELLAKYADSILRKSNKNVDIDDVEDCLSSIIIIFRYVEDKDVFQNFYTKLLAKRLVNG 472          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL3_CAEEL (Cullin-3 OS=Caenorhabditis elegans GN=cul-3 PE=1 SV=2)

HSP 1 Score: 125.176 bits (313), Expect = 4.943e-28
Identity = 80/271 (29.52%), Postives = 145/271 (53.51%), Query Frame = 3

Query:    6 LECTSEFYAAEGMKYMQ-QSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAIL---DKGFTMLMDGHRTEDLQRMYSLFSRVN--------ALESLRQALAMYIRRTGHGIVMDEEKDKD---MVSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLINLRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKVTVGERLLPLMQKNL*XPS*RLDGGTQFTNKL 773
            L+ TS++Y      ++   +D   YL  VEI +H+E  R   YLD  T   ++   +  ++  HI  I+   + G   +++  + EDL R++ +F R+          L++L +A++ Y+  TG  IV +E+  K+    V+ LL+ K    ++   +F+ +  F N  +  FE  +N  +  P E +A ++D+ LR+G K  S+ E++  LD V++LFR++Q KDVFE ++K+ L K++ + +     ++K L     + + G QFT KL
Sbjct:  208 LKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSP-EFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKAL-LAKLKTECGCQFTQKL 476          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL1_PONAB (Cullin-1 OS=Pongo abelii GN=CUL1 PE=2 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 1.237e-27
Identity = 77/240 (32.08%), Postives = 124/240 (51.67%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSRV-NALESLRQALAMYIRRTGHGIVMD-----EEKDKDMVSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLINLR--------QNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKV 680
            FL  T  FY  E  +++QQ+ V +Y+K  E RL EE  R  +YL  ST+  L    E+ L+E+H+  I    F  L+D  + EDL RMY+L SR+ + L  L++ L  +I   G   +           K  V ++L+     + +   +F+ +  F   +  A    IN           ++  EL+A++ D  L+  +K   E ELE TL++V+V+F++I+ KDVF+ FY K L K++
Sbjct:  236 FLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLE-IFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRL 474          

HSP 2 Score: 23.0978 bits (48), Expect = 1.237e-27
Identity = 12/18 (66.67%), Postives = 12/18 (66.67%), Query Frame = 2

Query:  698 ASIDAEESMIXKLKTGWG 751
            AS DAE SMI KLK   G
Sbjct:  480 ASDDAEASMISKLKQACG 497          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL1_MOUSE (Cullin-1 OS=Mus musculus GN=Cul1 PE=1 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 1.237e-27
Identity = 77/240 (32.08%), Postives = 124/240 (51.67%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSRV-NALESLRQALAMYIRRTGHGIVMD-----EEKDKDMVSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLINLR--------QNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKV 680
            FL  T  FY  E  +++QQ+ V +Y+K  E RL EE  R  +YL  ST+  L    E+ L+E+H+  I    F  L+D  + EDL RMY+L SR+ + L  L++ L  +I   G   +           K  V ++L+     + +   +F+ +  F   +  A    IN           ++  EL+A++ D  L+  +K   E ELE TL++V+V+F++I+ KDVF+ FY K L K++
Sbjct:  236 FLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLE-IFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRL 474          

HSP 2 Score: 23.0978 bits (48), Expect = 1.237e-27
Identity = 12/18 (66.67%), Postives = 12/18 (66.67%), Query Frame = 2

Query:  698 ASIDAEESMIXKLKTGWG 751
            AS DAE SMI KLK   G
Sbjct:  480 ASDDAEASMISKLKQACG 497          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL1_HUMAN (Cullin-1 OS=Homo sapiens GN=CUL1 PE=1 SV=2)

HSP 1 Score: 121.709 bits (304), Expect = 1.237e-27
Identity = 77/240 (32.08%), Postives = 124/240 (51.67%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSRV-NALESLRQALAMYIRRTGHGIVMD-----EEKDKDMVSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLINLR--------QNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKV 680
            FL  T  FY  E  +++QQ+ V +Y+K  E RL EE  R  +YL  ST+  L    E+ L+E+H+  I    F  L+D  + EDL RMY+L SR+ + L  L++ L  +I   G   +           K  V ++L+     + +   +F+ +  F   +  A    IN           ++  EL+A++ D  L+  +K   E ELE TL++V+V+F++I+ KDVF+ FY K L K++
Sbjct:  236 FLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLE-IFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRL 474          

HSP 2 Score: 23.0978 bits (48), Expect = 1.237e-27
Identity = 12/18 (66.67%), Postives = 12/18 (66.67%), Query Frame = 2

Query:  698 ASIDAEESMIXKLKTGWG 751
            AS DAE SMI KLK   G
Sbjct:  480 ASDDAEASMISKLKQACG 497          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL1_CAEEL (Cullin-1 OS=Caenorhabditis elegans GN=cul-1 PE=1 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 1.878e-27
Identity = 81/244 (33.20%), Postives = 124/244 (50.82%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQS-DVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSRV-NALESLRQALAMYIRRTGHG----IVMDEEKDKDM-VSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLIN-----------LRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKV 680
            FLE T  FY  E   ++    +V DY+  VE RL++E +RC LYL+ ST+ PL    E  L+   +   L + F  L+   R +DL RM+ L  RV N L+ LR++L  +I + GH     + M+   D  + V +LLE      ++  +SF     F  ++  A    IN            +  + AEL+A++ D+ LR  +K   E ELE    K++V+F++I  KDVF  FY K   K++
Sbjct:  236 FLEATRGFYTQEAANFLSNGGNVTDYMIKVETRLNQEDDRCQLYLNSSTKTPLATCCESVLISNQLD-FLQRHFGGLLVDKRDDDLSRMFKLCDRVPNGLDELRKSLENHIAKEGHQALERVAMEAATDAKLYVKTLLEVHERYQSLVNRSFKNEPGFMQSLDKAATSFINNNAVTKRAPPQAQLTKSAELLARYCDQLLRKSSKMPDEAELEELQTKIMVVFKYIDDKDVFSKFYTKMFSKRL 478          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL1_DICDI (Cullin-1 OS=Dictyostelium discoideum GN=culA PE=1 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 5.466e-27
Identity = 77/247 (31.17%), Postives = 128/247 (51.82%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSRV-NALESLRQALAMYIRRTG---------HGIVMDEEKDKDMVSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLIN--------LRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKVTVG 689
            FL  T  +Y  E  K++ ++ V DY+K VE RL+EE +R   YL  +T   LIA  E+ L+E+H+  I ++ F  L++  +  DL RMYSL SR+   LE LR  L  +++  G         +G++    + K  + +LL+     + +   +F  +  F  ++  A    IN           ++  EL+A+F D  L+       E E+E  L+ V+++F++I+ KDVF+ FY K L K++  G
Sbjct:  227 FLTATENYYTNESAKFISENSVADYMKKVETRLNEEVKRVQQYLHQNTESELIAKCEKVLIEKHVEVIWNE-FQTLLEKDKIPDLTRMYSLLSRIPRGLEPLRTTLEKHVQNVGLQAVSSIATNGVI----EPKVYIETLLKVFKKYNELVTGAFRSDTGFVASLDKACRRFINENAVTIAAKSSSKSPELLARFTDFLLKKSPNNPEESEMEQLLNDVMIVFKYIEDKDVFQDFYSKMLAKRLIHG 468          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL3_SCHPO (Cullin-3 OS=Schizosaccharomyces pombe GN=cul3 PE=1 SV=2)

HSP 1 Score: 112.849 bits (281), Expect = 2.539e-24
Identity = 77/249 (30.92%), Postives = 120/249 (48.19%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDK---GFTMLMDGHRTEDLQRMYSLFSRVN-ALESLRQALAMYIRRTGHGIVMDEEKDKDMVSSL----LEFKASLDTIWEQ---------------SFSKNEAFCNTIKDAFEYLINLRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKV 680
            FL  T  FY  E    +    V +YLK  E R  EE ER   YL      PL++  E +LL +H+  +L+    GF  ++D    E LQ +Y  FSRV   ++SL++ LA Y+    HG +++E   + +   +    L   A++ T+W Q               +   + +  N++ DAF   ++    R  E I+ F+D+ L+   +   E  +E TL   + LFRFI  KDVFE +YK  L K++
Sbjct:  232 FLSYTRNFYEIESSTVIGVFGVVEYLKKAEKRFEEEKERSKNYLFTKIASPLLSVVEDELLSKHLDDLLENQSTGFFSMIDSSNFEGLQLVYESFSRVELGVKSLKKYLAKYVAH--HGKLINETTSQALEGKMAVGRLSSNATMATLWVQKVLALWDRLNTIISTTMDADRSILNSLSDAFVTFVD-GYTRAPEYISLFIDDNLKKDARKAIEGSIEATLQNSVTLFRFISEKDVFEKYYKTHLAKRL 477          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL4_SCHPO (Cullin-4 OS=Schizosaccharomyces pombe GN=cul4 PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 4.331e-24
Identity = 76/269 (28.25%), Postives = 130/269 (48.33%), Query Frame = 3

Query:    3 FLECTSEFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDVSTRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSRVNALESLRQALAMYIRRTGHGIVMDEEKDKDMVSSLLEFKASLDTIWEQSFSKNEAFCNTIKDAFEYLIN----LRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKVTVGE--------RLLPLMQKNL*XPS*RLDGGTQFTNKL 773
            +L   S FY  E  + +Q+  + +YL++    L  E      +  V  +K +  T +R L+  H+   L KG +  ++       + +Y+L    +  E L Q  +  +   G  +V DE KD  +V  LL F   L  + ++SF  +E     ++ AFE  IN     ++  PA LIAK++D  LR G + +  + L+    ++L LFR+I  KD+FEA+YK D+ K++ + +         LL +++K           G+QFT+ L
Sbjct:  207 YLVMLSRFYDTESSQKIQELPLEEYLEYAMSSLEREDAYVEKFDIVRDKKSIRETVQRCLITSHLDT-LTKGISQFIEKRDAHSCKLLYALLQFNHETEYLIQPWSDCLVDVGFKLVNDESKDDTLVQELLSFHKFLQVVVDESFLHDETLSYAMRKAFETFINGAKGSQREAPARLIAKYIDYLLRVGEQASGGKPLKEVFSEILDLFRYIASKDIFEAYYKLDIAKRLLLNKSASAQNELMLLDMLKKTC---------GSQFTHSL 465          

BLAST of EY680325 vs. ExPASy Swiss-Prot
Match: CUL4_CAEEL (Cullin-4 OS=Caenorhabditis elegans GN=cul-4 PE=1 SV=3)

HSP 1 Score: 108.997 bits (271), Expect = 3.666e-23
Identity = 79/257 (30.74%), Postives = 138/257 (53.70%), Query Frame = 3

Query:   21 EFYAAEGMKYMQQSDVPDYLKHVEIRLHEEHERCLLYLDV-STRKPLIATAERQLLERHISAILDKGFTMLMDGHRTEDLQRMYSLFSR-VNALESLRQALAMYIRRTGHGIVMDEEKDKDMVSSLLEFKASLDTIWEQSF-SKNEA--FCNTIKDAFEYLINLRQNRPAELIAKFLDEKLRAGNKGTSEEE-LEGTLDKVLVLFRFIQGKDVFEAFYKKDLCKKVTVGERLLPLMQKNL*XPS*RLDGGTQFTNKL 773
            E Y  E +  + + +  DY+++ E +++   +   +  D  S  K + AT    L+++ I  IL   F  L+D     D+ RM++L  + V   + +R   + Y+++ G  ++     D+D+VS LL FK  +D I   SF S N+       + DAFE  +N + +R AELI+K     L + NK  S++  L+  +D+ +VLFR+++GKDVFEA+YK+ L K++ + ER   +  + +     + + G+ FT KL
Sbjct:  308 EHYNNERIDKVPKMNCNDYMEYCEDQINRYSQLVKVNFDEPSALKDVQATVTNCLIQQAIPEILTHDFDDLIDSDNISDIGRMFNLCRQCVGGEDEVRTQFSKYLKKRGEKLIATCP-DEDLVSELLAFKKKVDFIMTGSFKSANDPVKMRQCLSDAFESFVNKQVDRSAELISKHFHTLLHSSNKNVSDDTTLDQMVDEAIVLFRYLRGKDVFEAYYKRGLAKRLFL-ERSASVDAEKMVLCKLKTECGSAFTYKL 562