EY659448

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 1.358e-29
Identity = 74/209 (35.41%), Postives = 115/209 (55.02%), Query Frame = 1

Query:   40 SLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSL 666
            +L +LG+ YLDLYL+HWP      F   ++    SGS + +F++ +++ W+ +E LVD+GLV++IG+SNF V  + E+L +A+I PA NQVELHPF  Q EL KFC    IH++A++PLG                                +G  +    V  IA K+ KT    + +W +Q+  SV+P    P R+ +N D+F++ +
Sbjct:   97 TLSDLGLQYLDLYLVHWPVA----FEYTSNDIQTSGSTQ-EFVS-IRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLG--------------------------------NGAFVDNEEVGAIAKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEI 267          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: AK1A1_PONAB (Alcohol dehydrogenase [NADP+] OS=Pongo abelii GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 1.358e-29
Identity = 81/227 (35.68%), Postives = 122/227 (53.74%), Query Frame = 1

Query:   31 VRASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGP----MLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            ++ +L +L + YLDLYLMHWP   A   GD   P +  G+      +  K+ WK LE LV  GLVRA+G+SNF   QI ++L  A + PAV QVE HP+  Q+EL+  CQ++G+ V+A++PLG                             R+   P    +L+  VV  +A+K+  +P Q +LRW +QR    +P  + P RI +NI +F ++ S +E  +LN +
Sbjct:   95 LQKTLADLQLEYLDLYLMHWPY--AFERGDNPFPKNADGTICYDSTH-YKETWKALEALVAKGLVRALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLAVTAYSPLG--------------------------SSDRAWRDPDEPVLLEEPVVLALAEKYGGSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNAL 292          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: AK1BA_HUMAN (Aldo-keto reductase family 1 member B10 OS=Homo sapiens GN=AKR1B10 PE=1 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 2.316e-29
Identity = 84/227 (37.00%), Postives = 125/227 (55.07%), Query Frame = 1

Query:   19 PLVR--VRASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSE---RRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFA--KIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDE 678
            PLVR     +L +L ++YLD+YL+HWP+   SG  D   P    G+    +  FL+    AW+ +E LVD GLV+A+GVSNF   QI++LL     K  P  NQVE HP+  Q++L+++C SKGI V+A++PLG                            ++     +L+   + EIA KHKKT  Q ++R+ +QR   V+P  + P RI +NI +F + LS++E
Sbjct:   87 PLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSG--DDLFPKDDKGNAIGGKATFLD----AWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPW----------------------AKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEE 285          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: ALD1_MOUSE (Aldose reductase-related protein 1 OS=Mus musculus GN=Akr1b7 PE=2 SV=4)

HSP 1 Score: 127.872 bits (320), Expect = 8.802e-29
Identity = 78/220 (35.45%), Postives = 122/220 (55.45%), Query Frame = 1

Query:   40 SLXNLGVTYLDLYLMHWPECSASGF--GDATDPPSKSGS---ERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFA--KIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDE 678
            +L +L + YLDLYL+HWP+    GF  G+A  P    G     +  FL+    AW+ +E LVD GLV+A+G+SNF   QI+ LL     K  P  NQ+E HP+  Q++L+++CQSKGI V+A++PLG                            ++     ++++  + EIA KHKKT  Q ++R+ +QR   V+P  + P RI++N+ +F + LS ++
Sbjct:   96 TLSDLKLDYLDLYLVHWPQ----GFQAGNALLPKDNKGKVLLSKSTFLD----AWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLGSPDRPY----------------------AKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEED 285          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: XYL1_ASPNG (NAD(P)H-dependent D-xylose reductase OS=Aspergillus niger GN=xyrA PE=3 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 2.561e-28
Identity = 75/240 (31.25%), Postives = 124/240 (51.67%), Query Frame = 1

Query:   34 RASLXNLGVTYLDLYLMHWPECSASGFGDATDPPS-KSGSERRQFLNR-LKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHG----PMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXIEPXVCLFGNEPL 735
            R  L + G+ Y DLY++H+P            PP  KS  +  +F N  +++ W  +E LVD  L R+IG+SNF    + +LL++A+I PA  Q+E HP+  Q  LV++ Q +G+ V+A++  G                       +SF      +     P+ +  +V  IA+KH +TP Q +LRW  QRG +V+P    P R+++N+D+  W+L  +E   ++ ++    L  N+PL
Sbjct:   95 RKQLADWGIDYFDLYIVHFPISLKYVDPAVRYPPGWKSEKDELEFGNATIQETWTAMESLVDKKLARSIGISNFSAQLVMDLLRYARIRPATLQIEHHPYLTQTRLVEYAQKEGLTVTAYSSFG----------------------PLSFLELSVQNAVDSPPLFEHQLVKSIAEKHGRTPAQVLLRWATQRGIAVIPKSNNPQRLKQNLDVTGWNLEEEEIKAISGLDRG--LRFNDPL 310          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: ALDR_RABIT (Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3)

HSP 1 Score: 125.176 bits (313), Expect = 5.706e-28
Identity = 79/224 (35.27%), Postives = 122/224 (54.46%), Query Frame = 1

Query:   40 SLXNLGVTYLDLYLMHWPECSASGFGDATD--PPSKSGS---ERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFA--KIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRL 690
            +L +L + YLDLYL+HWP    +GF   ++  P   +G+       FL+     W+ +EGLVD GLV++IGVSNF   QI+ +L     K  PAVNQ+E HP+  Q++L+++C SKGI V+A++PLG                            ++     +L+   +  IADKHKKT  Q ++R+ +QR   V+P  + P RI +N  +F + LS+++   L
Sbjct:   96 TLNDLKLDYLDLYLIHWP----TGFKHGSEYFPLDAAGNVIPSDTDFLD----TWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPW----------------------AKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVVIPKSVTPARIAENFQVFDFELSSEDMTTL 289          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: YTBE_BACSU (Uncharacterized oxidoreductase ytbE OS=Bacillus subtilis GN=ytbE PE=1 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 7.452e-28
Identity = 72/228 (31.58%), Postives = 111/228 (48.68%), Query Frame = 1

Query:   16 DPLVRVRASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            + L     SL  LG+ YLDLYL+HWP                          + K+AW+ LE L   G ++AIGVSNF +  +++L+  A+I P +NQVE HP   Q EL+++CQ++GI + A +PL                                + G +L   V+++IA  + K+  Q ILRW LQ G   +P   K  RI++N  +F + L+ D+ NR++ +
Sbjct:   93 ETLAAFETSLSKLGLDYLDLYLIHWP-----------------------VEGKYKEAWRALETLYKEGRIKAIGVSNFQIHHLEDLMTAAEIKPMINQVEFHPRLTQKELIRYCQNQGIQMEAWSPL--------------------------------MQGQLLDHPVLADIAQTYNKSVAQIILRWDLQHGIITIPKSTKEHRIKENASVFDFELTQDDMNRIDAL 265          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: GR_BACSU (Glyoxal reductase OS=Bacillus subtilis GN=yvgN PE=1 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 9.732e-28
Identity = 77/226 (34.07%), Postives = 109/226 (48.23%), Query Frame = 1

Query:   22 LVRVRASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            L     SL  L + YLDLYL+HWP                         ++ K  W+ LE L   G +RAIGVSNF V  ++ELLK A+I P VNQVE HP   Q EL  +C+ +GI + A +PL                                + G +L   V+++IA+KH K+  Q ILRW LQ G   +P  +K  RI +N DIF + LS ++ ++++ +
Sbjct:   91 LAAFEKSLERLQLDYLDLYLIHWPG-----------------------KDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAWSPL--------------------------------MQGQLLDNEVLTQIAEKHNKSVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDAL 261          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: YPR1_YEAST (Putative reductase 1 OS=Saccharomyces cerevisiae GN=YPR1 PE=1 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.271e-27
Identity = 79/239 (33.05%), Postives = 121/239 (50.63%), Query Frame = 1

Query:   16 DPLVRVRASLXNLGVTYLDLYLMHWPECSASGFGDATD------PPSKSGS---ERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFA--KIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            DP   +  SL  LG+ Y+DLYLMHWP    +     TD      P  + G+   + +++     K W+ ++ L  +G  +A+GVSNF ++ IKELL+    K++PA NQ+E+HP   QDEL+ FC+ KGI V A++P G                              S + P+LK   + ++A KH   P Q I+ W +QRG  VL   + P+RI  N  IF  +L  D++  ++ +
Sbjct:   89 DPEAALNKSLKRLGLDYVDLYLMHWPVPLKTD--RVTDGNVLCIPTLEDGTVDIDTKEW--NFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFG------------------------------SANAPLLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIF--TLPEDDFKTISNL 291          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: ALD2_MOUSE (Aldose reductase-related protein 2 OS=Mus musculus GN=Akr1b8 PE=1 SV=2)

HSP 1 Score: 124.02 bits (310), Expect = 1.271e-27
Identity = 77/216 (35.65%), Postives = 118/216 (54.63%), Query Frame = 1

Query:   40 SLXNLGVTYLDLYLMHWPECSASGFG-DATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFA--KIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDE 678
            +L +L + YLDLYL+HWP+    G      D   +  + +  FL    +AW+ +E LVD GLV+A+GVSNF   QI+ LL     K  P  NQVE HP+  Q++L+++C SKGI V+A++PLG                            ++     +L+   + EIA KH+KT  Q ++R+ +QR   V+P  + P RI++NI +F + LS++E
Sbjct:   96 TLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTFL----EAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDR----------------------PSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEE 285