EY659448

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: GRE3_YEAST (NADPH-dependent aldose reductase GRE3 OS=Saccharomyces cerevisiae GN=GRE3 PE=1 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 2.656e-17
Identity = 66/227 (29.07%), Postives = 107/227 (47.14%), Query Frame = 1

Query:    7 YKPDPL-VRVRASLXNLGVTYLDLYLMHWP---------ECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPML-KLSVVSEIADKHK-KTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDI 651
            + PD + + ++ +L ++G+ YLDLY +H+P         E    GF    D   K           +   ++ LE  VD GL+++IGVSNF  S I++LL+  +I P   Q+E HP+  Q+ LV+FC+   I V A++  G                       I      +   P L +  V+ +++  H   T  Q +LRW  QRG +V+P   K +R+  N++I
Sbjct:   84 HHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHV--PIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSF-------------------IEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEI 289          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: Y4149_MYCPA (Uncharacterized oxidoreductase MAP_4149 OS=Mycobacterium paratuberculosis GN=MAP_4149 PE=3 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 3.469e-17
Identity = 62/225 (27.56%), Postives = 102/225 (45.33%), Query Frame = 1

Query:   34 RASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDS---GLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            + SL  LG+ YLDLYL+HWP  +                        L K  +  EG++++   G VR+IGVSNF    +  +++    +PAVNQVELHP   Q EL +      +   +++PLGV                                G +++   V+ IA ++ +TP Q ++RW LQ    V+    KP+R+ +N+D+F ++L  +    +  +
Sbjct:  102 KESLDRLGLDYLDLYLIHWPAPT------------------------LGKYVESFEGMIEARERGHVRSIGVSNFTEDLLATVIEETNEVPAVNQVELHPRLNQAELRQVHAQHDVTTQSYSPLGV--------------------------------GRLIEEPTVTTIAAEYGRTPAQVLVRWNLQLDNVVVSRSSKPERVAENLDVFDFTLEPEHMEAIEGL 270          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: I3ACR_SCHPO (NAD/NADP-dependent indole-3-acetaldehyde reductase OS=Schizosaccharomyces pombe GN=SPAC19G12.09 PE=1 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.722e-16
Identity = 63/222 (28.38%), Postives = 102/222 (45.95%), Query Frame = 1

Query:   40 SLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHP--FWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            SL  LG  YLDLYL+H P      F +   P              + + WK +E  + +GLV ++GVSNF +  ++ELLK + I P VNQ+E HP  +     LV+FCQSKGI V  + PL                      P +     R   GP+ + +    +  K+  +  Q +L+W   +G   +    K +R+++ ++  S++L   + + L  +
Sbjct:   94 SLRKLGTDYLDLYLLHSP----IPFYEKKIP--------------ISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYGPLS---------------------PLV-----RDAQGPVAEFT--KSLESKYHVSDTQILLKWAYSKGVIPITTTSKIERMKECLNFDSFTLDKADIDELGTL 269          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 3.836e-16
Identity = 63/223 (28.25%), Postives = 108/223 (48.43%), Query Frame = 1

Query:   40 SLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLK--FAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXIE 702
            SL  L + Y+DLYL+H+P     G  D   P  + G+     ++ L   W+ +E   D+GL ++IGVSNF   Q++++L     K  P  NQVE H +  Q +L+ +C+   I + A+  LG                      R  +  +      +L   ++  +A K+K+TP    LR+ L+RG   L      +RIR+N+ +F + L++D+   L+ ++
Sbjct:  102 SLRKLNLDYVDLYLIHFPVSLKPG--DELLPQDEHGNLILDTVD-LCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGT--------------------QRYKYCINEDT-PVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQVFDFQLASDDMEILDNLD 300          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: AK1CL_RAT (Aldo-keto reductase family 1 member C21 OS=Rattus norvegicus GN=Akr1c21 PE=2 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 1.116e-15
Identity = 65/209 (31.10%), Postives = 99/209 (47.37%), Query Frame = 1

Query:   31 VRASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFA--KIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDI 651
            +  SL  L + Y+DLYL+H+P   A   GD   P  + G      ++ L   W+ +E   D+GL ++IGVSNF   Q++++L     K  P  NQVE H +  Q +L+ FC++ GI + A+  LG                                   +L   V+S +A K+ +TP    LR  LQRG  VL   LK +RI++N+ +
Sbjct:   99 LECSLKKLQLDYVDLYLIHFP--MALKPGDENFPVDEHGKLLFDTVD-LCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFCKTNGIILVAYGVLGTQRYNGWVDQNSPV---------------------LLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTSLKEERIKENMKL 283          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: AKC1H_MOUSE (Aldo-keto reductase family 1 member C18 OS=Mus musculus GN=Akr1c18 PE=2 SV=2)

HSP 1 Score: 82.8037 bits (203), Expect = 3.247e-15
Identity = 63/223 (28.25%), Postives = 106/223 (47.53%), Query Frame = 1

Query:   40 SLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLK--FAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXIE 702
            SL  L + Y+DLYL+H+P     G  +   P  + G+     ++ L   W+ +E   D+GL ++IGVSNF   Q++ +L     K  P  NQVE H +  Q +L+ +C+   I + A+  LG                      R  +  +      +L   V+  +A K+K+TP    LR+ L RG   L      +RIR+N+ +F + L++D+   L+ ++
Sbjct:  102 SLRKLNLDYVDLYLIHFPVSLKPG--NELLPKDEHGNLIFDTVD-LCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGT--------------------QRYKYCINEDT-PVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMKILDGLD 300          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: YJ66_YEAST (Uncharacterized oxidoreductase YJR096W OS=Saccharomyces cerevisiae GN=YJR096W PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 7.234e-15
Identity = 58/215 (26.98%), Postives = 96/215 (44.65%), Query Frame = 1

Query:   55 GVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLKFAKI--MPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLN 693
            G+ Y+DL L+H P                 GS+ R       + W+ ++  VD GLV++IGVSN+G   I ELL + ++   P VNQ+E+ P+  + EL  +C+SKG+ V A  PL                                 HG  +    + ++  +  + P Q ++RW LQ G   LP      R+  N+  +++ LS+++   L+
Sbjct:  105 GLQYIDLLLIHSP---------------LEGSKLRL------ETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELADYCKSKGLVVEAFAPL--------------------------------CHGYKMTNPDLLKVCKEVDRNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYNFELSDEQMKFLD 266          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: Y3816_MYCA1 (Uncharacterized oxidoreductase MAV_3816 OS=Mycobacterium avium (strain 104) GN=MAV_3816 PE=3 SV=2)

HSP 1 Score: 78.9518 bits (193), Expect = 4.689e-14
Identity = 56/224 (25.00%), Postives = 93/224 (41.52%), Query Frame = 1

Query:   37 ASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDS---GLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            ASL  LG+ Y+DLYL+HWP  +   + ++                          G++ S   G  R+IGVSNF    +  ++    + PAVNQ+ELHP   Q+ L K      +   ++TPL +                                G +     V+ +A ++ KT  Q +LRW LQ G +V+      + I  + D+F + L+ +  + +N +
Sbjct:  101 ASLERLGLDYVDLYLIHWPAPALGTYVNS------------------------FGGMIQSRGNGHARSIGVSNFTEEYLTTVIDLTFVTPAVNQIELHPLLNQEALRKTNAEHNVVTQSYTPLAL--------------------------------GKLNDHPTVNSVAAEYGKTASQVLLRWNLQLGNAVIFRSANAEHIASDFDVFDFELAAEHMDAINAL 268          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: DIDH_RAT (3-alpha-hydroxysteroid dehydrogenase OS=Rattus norvegicus GN=Akr1c9 PE=1 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 1.045e-13
Identity = 63/235 (26.81%), Postives = 111/235 (47.23%), Query Frame = 1

Query:    7 YKPDPLVR--VRASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDSGLVRAIGVSNFGVSQIKELLK--FAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            ++P+ LVR  +  +L +  + Y+DLY++H+P   A   GD   P  + G    + ++ +   W+ +E   D+GL ++IGVSNF   Q++ +L     K  P  NQVE H +  Q +++ +C+SK I + ++  LG                                   +L   V+  IA K+K+TP    LR+ LQRG   L       RI++   +F + L++++   L+ +
Sbjct:   90 HRPE-LVRTCLEKTLKSTQLDYVDLYIIHFP--MALQPGDIFFPRDEHGKLLFETVD-ICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPV---------------------LLDDPVLCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGL 299          

BLAST of EY659448 vs. ExPASy Swiss-Prot
Match: Y3007_MYCPA (Uncharacterized oxidoreductase MAP_3007 OS=Mycobacterium paratuberculosis GN=MAP_3007 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 2.327e-13
Identity = 55/224 (24.55%), Postives = 92/224 (41.07%), Query Frame = 1

Query:   37 ASLXNLGVTYLDLYLMHWPECSASGFGDATDPPSKSGSERRQFLNRLKKAWKFLEGLVDS---GLVRAIGVSNFGVSQIKELLKFAKIMPAVNQVELHPFWRQDELVKFCQSKGIHVSAHTPLGVXXXXXXXXXXXXXXXXXXXXPRISFXRSRSVHGPMLKLSVVSEIADKHKKTPEQGILRWGLQRGTSVLPCXLKPDRIRKNIDIFSWSLSNDEWNRLNXI 699
            ASL  LG+ Y+DLYL+HWP  +   + ++                          G++ S   G  R+IGVSNF    +  ++    + PAVNQ+ELHP   Q+ L K      +   ++TPL +                                G +     V+ +A ++ KT  Q +LRW LQ   +V+      + I  + D+F + L+ +  + +N +
Sbjct:   98 ASLERLGLDYVDLYLIHWPAPALGTYVNS------------------------FGGMIQSRGNGHARSIGVSNFTEEYLTTVIDLTFVTPAVNQIELHPLLNQEALRKTNAEHNVVTQSYTPLAL--------------------------------GKLNDHPTVNSVAAEYGKTASQVLLRWNLQLSNAVIFRSANAEHIASDFDVFDFELAAEHMDAINAL 265