EY649583

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51A_PIG (Lanosterol 14-alpha demethylase OS=Sus scrofa GN=CYP51A1 PE=2 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 5.108e-31
Identity = 74/215 (34.42%), Postives = 115/215 (53.49%), Query Frame = 2

Query:  113 MPISSKRLPPIVKGYPLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVY-QFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKWGDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFP-YLPIPSHXRRDPARKKLADIFANII 751
            +P  +K  P I    P +G  + F K PI  +   Y K G VF+  +  +  T+L+G + +A  F +   DL+ ++VY +   P FG GV +DV   +  EQ +     L +   + +V  +  E ++YF  WG+SGE +L   L  LIILTAS CL G+E+R +L + V+ L+     G    + L P +LP+PS  RRD A +++ +IF   I
Sbjct:   54 LPAGAKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFRQHVSIIEKETKEYFQSWGESGERNLFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAI 268          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_MYCTU (Lanosterol 14-alpha demethylase OS=Mycobacterium tuberculosis GN=cyp51 PE=1 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 6.904e-28
Identity = 72/211 (34.12%), Postives = 110/211 (52.13%), Query Frame = 2

Query:  119 ISSKRLPPIVKGYPLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVYQFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKWGDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLADIFANII 751
            +S+  LP +  G+   G L +F   PI +++    + G V T  L  + +  L G   +  FF+A + DL Q + Y F  P FG GVVFD     R+E       ALR  ++KG+   +  +     + WG++GE+DL      L I T+S CL+G++ RD+L    + L+H    G  P++ + PYLPI S  RRD AR  L  + A+I+
Sbjct:    1 MSAVALPRVSGGHDEHGHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAYPFMTPIFGEGVVFDASPERRKEMLH--NAALRGEQMKGHAATIEDQVRRMIADWGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIM 209          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_MYCBO (Lanosterol 14-alpha demethylase OS=Mycobacterium bovis GN=cyp51 PE=3 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 6.904e-28
Identity = 72/211 (34.12%), Postives = 110/211 (52.13%), Query Frame = 2

Query:  119 ISSKRLPPIVKGYPLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVYQFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKWGDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLADIFANII 751
            +S+  LP +  G+   G L +F   PI +++    + G V T  L  + +  L G   +  FF+A + DL Q + Y F  P FG GVVFD     R+E       ALR  ++KG+   +  +     + WG++GE+DL      L I T+S CL+G++ RD+L    + L+H    G  P++ + PYLPI S  RRD AR  L  + A+I+
Sbjct:    1 MSAVALPRVSGGHDEHGHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAYPFMTPIFGEGVVFDASPERRKEMLH--NAALRGEQMKGHAATIEDQVRRMIADWGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIM 209          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_USTMA (Lanosterol 14-alpha demethylase OS=Ustilago maydis GN=ERG11 PE=3 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 9.969e-27
Identity = 77/240 (32.08%), Postives = 122/240 (50.83%), Query Frame = 2

Query:   62 LLIMATIVVAKLISSLVMPISSKRLPPIVKGY-PLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVY-QFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFS--------KWGDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLADIFANII 751
            L+++  + V   ++S ++  + K  PP+V  + P+IG  + +   P     E   K G VFT  L  R IT  +GP+ S   F A    ++ ++ Y     P FG  VV+DV  ++  EQ +F    L +   + YV Q+V E  +Y          K   +  VD+   +  LIILTASR L G+EVR  L    + L+H    G  PI+ + P LP+PS+ +RD A+KK++  + +I+
Sbjct:   35 LVLLPLLAVVLNVASQLLLATPKNHPPVVFHFVPVIGSAIYYGIDPYKFFFECREKYGDVFTFVLLGRKITVALGPKGSNLVFNAKHQQVTAEDAYTHLTTPVFGKEVVYDVPNAVFMEQKKFVKVGLSIENFRVYVPQIVDEVREYIKSDARFSALKTRKTITVDIFQAMSELIILTASRTLQGKEVRQGLDKSFAQLYHDLDSGFTPINFVIPNLPLPSNFKRDRAQKKMSQFYQDIV 274          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_MYCVP (Lanosterol 14-alpha demethylase OS=Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) GN=cyp51 PE=3 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.440e-25
Identity = 68/208 (32.69%), Postives = 105/208 (50.48%), Query Frame = 2

Query:  128 KRLPPIVKGYPLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVYQFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKWGDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLADIFANII 751
            K +P +  G    G L +F   PI +++    + G V    L ++ +  L G E +  FF++ +S+L+Q E Y F  P FG GVVFD D   R E       ALR   +KG+   +  E       WG+SGE+DL      L I T++ CL+G + R++L    ++ +H    G  P+  + PYLPI S   RD AR  L ++  +++
Sbjct:    5 KEVPRVSGGEEEHGHLEEFRTDPIGLMKRVREECGDVGWFQLADKQVILLSGAEANEFFFRSSDSELNQAEAYPFMTPIFGEGVVFDADPERRAEMLH--NTALRGEHMKGHATTIEAEVRKMIEGWGESGEIDLLEFFAELTIYTSTACLIGLKFRNQLDSRFANYYHLLERGTDPLCYVDPYLPIESFRIRDEARAGLVELVQDVM 210          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_SCHPO (Lanosterol 14-alpha demethylase erg11 OS=Schizosaccharomyces pombe GN=erg11 PE=1 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.141e-22
Identity = 71/237 (29.96%), Postives = 115/237 (48.52%), Query Frame = 2

Query:   68 IMATIVVAKLISSLVMPISSK--RLPPIVKGY-PLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVYQ-FNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKW-----GDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLADIFANII 751
            I+ +I +A  +  ++  ++S+  + PPIV  + P +G  V +   P V  RE  +K G VFT     R +T  +G + +   F    +DL+ +E Y     P FG  VV+D+   +  E  +F    L  ++ + YV  ++ E + + S       G  G  DL   +  + I TASR L G EVR       + L+H    G  P++ +FP+LP+P + RRD A K +   +  II
Sbjct:    8 ILLSIALAWYVGYIINQLTSRNSKRPPIVFHWIPFVGSAVAYGMDPYVFFRECRAKYGDVFTFVCMGRKMTAFLGVQGNDFLFNGKLADLNAEEAYSHLTTPVFGKDVVYDIPNHVFMEHKKFIKSGLGFSQFRSYVPLILNEMDAFLSTSPDFGPGKEGVADLLKTMPVMTIYTASRTLQGAEVRKGFDAGFADLYHDLDQGFSPVNFVFPWLPLPRNRRRDRAHKIMQKTYLKII 244          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_YEAST (Lanosterol 14-alpha demethylase OS=Saccharomyces cerevisiae GN=ERG11 PE=1 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 9.656e-22
Identity = 69/237 (29.11%), Postives = 110/237 (46.41%), Query Frame = 2

Query:   65 LIMATIVVAKLISSLVMPISSKRLPPIVKGYPLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVY-QFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKWGD-------SGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLADIFANII 751
            LI+    +  ++  L+  +   R P +    P +G  V +   P     E   K G +F+  L  R +T  +GP+     F A  +D+S +  Y     P FG GV++D   S   EQ +F   AL     K YV  +  E   YF    +       +G +D+      + I TASR LLG+E+R KL  D + L+     G  PI+ +FP LP+  + +RD A+K ++  + ++I
Sbjct:   33 LIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLI 269          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_CANTR (Lanosterol 14-alpha demethylase OS=Candida tropicalis GN=ERG11 PE=3 SV=2)

HSP 1 Score: 103.605 bits (257), Expect = 1.647e-21
Identity = 72/247 (29.15%), Postives = 111/247 (44.94%), Query Frame = 2

Query:   29 MDETNKFYNVGLLIMATIVVA-----KLISSLVMPISSKRLPPIVKGYPLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVY-QFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYF-------SKWGDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLA 730
            +D  N F ++ L    TI+V       +   L+  +   R+P +    P  G    +   P     +   K G VF+  L  + +T  +GP+     + A  SD+S +E Y     P FG GV++D   S   EQ +F   AL     K YV ++  E  +YF       +K  D G   +      + I TASRCL G E+R       + L+     G  PI+ +FP LP+P + RRD A++K++
Sbjct:    8 IDGINYFLSLSLTQQITILVVFPFIYNIAWQLLYSLRKDRVPMVFYWIPWFGSAASYGMQPYEFFEKCRLKYGDVFSFMLLGKVMTVYLGPKGHEFIYNAKLSDVSAEEAYTHLTTPVFGKGVIYDCPNSRLMEQKKFAKFALTTDSFKTYVPKIREEVLNYFVNDVSFKTKERDHGVASVMKTQPEITIFTASRCLFGDEMRKSFDRSFAQLYADLDKGFTPINFVFPNLPLPHYWRRDAAQRKIS 254          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_CANGA (Lanosterol 14-alpha demethylase OS=Candida glabrata GN=ERG11 PE=3 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 1.394e-20
Identity = 67/237 (28.27%), Postives = 109/237 (45.99%), Query Frame = 2

Query:   65 LIMATIVVAKLISSLVMPISSKRLPPIVKGYPLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVYQ-FNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKW-------GDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIPSHXRRDPARKKLADIFANII 751
            +++A   V  +   L+  +   R P +    P +G  + +   P     +   K G +F+  L  R +T  +GP+     F A  +D+S +  Y     P FG GV++D       EQ +F   AL       YV  +  E   YF           +SG VD+      + I TASR LLG+E+RDKL  D + L+     G  PI+ +FP LP+  + +RD A++ ++  + ++I
Sbjct:   34 IMVALPFVYTITWQLLYSLRKDRPPLVFYWIPWVGSAIPYGTKPYEFFEDCQKKYGDIFSFMLLGRIMTVYLGPKGHEFIFNAKLADVSAEAAYSHLTTPVFGKGVIYDCPNHRLMEQKKFVKGALTKEAFVRYVPLIAEEIYKYFRNSKNFKINENNSGIVDVMVSQPEMTIFTASRSLLGKEMRDKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQQAISGTYMSLI 270          

BLAST of EY649583 vs. ExPASy Swiss-Prot
Match: CP51_PENIT (Eburicol 14-alpha-demethylase OS=Penicillium italicum GN=CYP51 PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 3.106e-20
Identity = 66/221 (29.86%), Postives = 103/221 (46.61%), Query Frame = 2

Query:   47 FYNVGLLIMATIVVAKLISSLVMPISSKRLPPIVKGY-PLIGGLVKFLKGPIVMIREEYSKLGSVFTVNLCNRNITFLIGPEVSAHFFKAPESDLSQQEVY-QFNVPTFGPGVVFDVDYSIRQEQFRFFTEALRVTKLKGYVDQMVVEAEDYFSKW----GDSGEVDLKFELEHLIILTASRCLLGREVRDKLFDDVSSLFHXP*HGMLPISVLFPYLPIP 691
            +Y  GL +++  +V  +I  L+    +++ PP+V  + P IG  + +   P        +K G +FT  L  +  T  +G E +         D++ +EVY +   P FG  VV+D   S   EQ +F    L    L+ YV  +  E   Y        G SG +DL   +  + I TA+R L G EVR KL  + + LFH    G  PI+ + P+ P+P
Sbjct:   16 YYTTGLFLVS--IVLNVIKQLIF--YNRKEPPVVFHWIPFIGSTIAYGMDPYQFFFASRAKYGDIFTFILLGKKTTVYLGVEGNEFILNGKLKDVNAEEVYGKLTTPVFGSDVVYDCPNSKLMEQKKFIKYGLSQEALESYVPLIADETNAYIKSSPNFKGQSGTIDLAAAMAEITIFTAARTLQGEEVRSKLTSEFADLFHDLDLGFSPINFMLPWAPLP 232