CX300749

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: BRSK1_MOUSE (BR serine/threonine-protein kinase 1 OS=Mus musculus GN=Brsk1 PE=2 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 2.574e-30
Identity = 68/148 (45.95%), Postives = 94/148 (63.51%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFA 549
            Y L + LG G   +VKL +H  TGQK AVKIV+++KLS+     +  EI IL  ++HPH++KL + Y+     Y+V E V+GGELFD +V K   T KEAR   + ++  + + H   I HRDLKPENLLL    + ++I+IADFG A
Sbjct:   34 YRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL---DEKNNIRIADFGMA 178          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: KCC4_RAT (Calcium/calmodulin-dependent protein kinase type IV OS=Rattus norvegicus GN=Camk4 PE=1 SV=3)

HSP 1 Score: 131.339 bits (329), Expect = 3.362e-30
Identity = 69/147 (46.94%), Postives = 97/147 (65.99%), Query Frame = 1

Query:  121 ELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIK 561
            ELG GA S+V       T +  A+K++ K      D + +  EI +L  L HP+IIKL E ++  T+  +V ELV GGELFDRIV K +Y+E++A D +K +LE +AY+H+ GIVHRDLKPENLL  +   D+ +KIADFG +K ++
Sbjct:   47 ELGRGATSIVYRCKQKGTQKPYALKVLKKTV----DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVE 189          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: KCC4_HUMAN (Calcium/calmodulin-dependent protein kinase type IV OS=Homo sapiens GN=CAMK4 PE=1 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 3.362e-30
Identity = 69/147 (46.94%), Postives = 97/147 (65.99%), Query Frame = 1

Query:  121 ELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIK 561
            ELG GA S+V       T +  A+K++ K      D + +  EI +L  L HP+IIKL E ++  T+  +V ELV GGELFDRIV K +Y+E++A D +K +LE +AY+H+ GIVHRDLKPENLL  +   D+ +KIADFG +K ++
Sbjct:   51 ELGRGATSIVYRCKQKGTQKPYALKVLKKTV----DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVE 193          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: BRSK1_HUMAN (BR serine/threonine-protein kinase 1 OS=Homo sapiens GN=BRSK1 PE=1 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 3.362e-30
Identity = 67/148 (45.27%), Postives = 94/148 (63.51%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFA 549
            Y L + LG G   +VKL +H  TGQK A+KIV+++KLS+     +  EI IL  ++HPH++KL + Y+     Y+V E V+GGELFD +V K   T KEAR   + ++  + + H   I HRDLKPENLLL    + ++I+IADFG A
Sbjct:   50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL---DEKNNIRIADFGMA 194          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: MARK3_RAT (MAP/microtubule affinity-regulating kinase 3 OS=Rattus norvegicus GN=Mark3 PE=2 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 4.391e-30
Identity = 66/149 (44.30%), Postives = 96/149 (64.43%), Query Frame = 1

Query:  103 NYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFA 549
            NY L + +G G F+ VKLA H+ TG++ A+KI+ K +L+    Q L  E++I+  L+HP+I+KLFE  +     Y++ E  +GGE+FD +VA     EKEAR   + ++  + Y H+  IVHRDLK ENLLL +   D +IKI DFGF+
Sbjct:   55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA---DMNIKITDFGFS 200          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: KCC1A_HUMAN (Calcium/calmodulin-dependent protein kinase type 1 OS=Homo sapiens GN=CAMK1 PE=1 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 7.490e-30
Identity = 67/143 (46.85%), Postives = 98/143 (68.53%), Query Frame = 1

Query:  124 LGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAK 552
            LG+GAFS V LA    T +  A+K ++K+ L  ++  ++  EI +L ++ HP+I+ L + Y+ G   Y++ +LV+GGELFDRIV K  YTE++A  LI  +L+ + Y+H +GIVHRDLKPENLL  S  +DS I I+DFG +K
Sbjct:   26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKE-GSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSK 167          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: MRKC_DICDI (Probable serine/threonine-protein kinase MARK-C OS=Dictyostelium discoideum GN=mrkC PE=3 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 9.782e-30
Identity = 74/167 (44.31%), Postives = 101/167 (60.48%), Query Frame = 1

Query:   73 MHVGNKKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYD----EGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIK 561
            MHVG+      Y + + LG+G F  VKL  ++ T +  A+K +   KLS +  +    EI I+  LDHP+I+KL +  D    EGT  Y++ E V+GGELFD IVA+ +  EKEAR   + M+  + Y H   IVHRDLKPENLLL S   + DIKI+DFG +  I+
Sbjct:   41 MHVGS------YEVGKTLGNGTFGKVKLGTNICTKENVAIKFIKNNKLSGKQKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTT-YLIVEYVSGGELFDYIVAREYIKEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDS---NGDIKISDFGLSNNIQ 197          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: KIN11_ARATH (SNF1-related protein kinase catalytic subunit alpha KIN11 OS=Arabidopsis thaliana GN=KIN11 PE=1 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 9.782e-30
Identity = 70/162 (43.21%), Postives = 101/162 (62.35%), Query Frame = 1

Query:   82 GNKKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSD-EDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIKD 564
            G +    NY L + LG G+F  VK+A H+ TG K A+KI++++K+ + E  + +  EI+IL    HPHII+ +E  +  +D Y+V E V  GELFD IV K    E EAR+  + ++  + Y H+  +VHRDLKPENLLL S     +IKIADFG +  ++D
Sbjct:   12 GVESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSR---CNIKIADFGLSNVMRD 170          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: CHK2_MOUSE (Serine/threonine-protein kinase Chk2 OS=Mus musculus GN=Chek2 PE=2 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 9.782e-30
Identity = 71/171 (41.52%), Postives = 106/171 (61.99%), Query Frame = 1

Query:   88 KKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLS------DEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIKDLSPKET 582
            K+    Y++++ LGSGA   VK+A   +T QK A+KI+SK++ +       +   ++  EI+IL +L+HP IIK+ + +D   D+YIV EL+ GGELFDR+V      E   +     ML  + Y+H+ GI+HRDLKPEN+LL S+ +D  IKI DFG +K + + S   T
Sbjct:  218 KELRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFD-AEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRT 387          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: SIK3_MOUSE (Serine/threonine-protein kinase SIK3 OS=Mus musculus GN=Sik3 PE=1 SV=3)

HSP 1 Score: 129.413 bits (324), Expect = 1.278e-29
Identity = 67/148 (45.27%), Postives = 95/148 (64.19%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFA 549
            Y + R +G G F+VVK A HL T  K A+KI+ K +L +E+ + +  E+QI+  L HPHII+L++  +     Y+VTE  +GGE+FD +VA     EKEAR   K ++  + + H   IVHRDLK ENLLL +   + +IKIADFGF+
Sbjct:    8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDA---NLNIKIADFGFS 152