CX300749

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: SIK3_HUMAN (Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3)

HSP 1 Score: 129.028 bits (323), Expect = 1.669e-29
Identity = 67/148 (45.27%), Postives = 95/148 (64.19%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFA 549
            Y + R +G G F+VVK A HL T  K A+KI+ K +L +E+ + +  E+QI+  L HPHII+L++  +     Y+VTE  +GGE+FD +VA     EKEAR   K ++  + + H   IVHRDLK ENLLL +   + +IKIADFGF+
Sbjct:    8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDA---NLNIKIADFGFS 152          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: SIK2_CHICK (Serine/threonine-protein kinase SIK2 OS=Gallus gallus GN=SIK2 PE=2 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 2.179e-29
Identity = 73/177 (41.24%), Postives = 99/177 (55.93%), Query Frame = 1

Query:   52 SAASANKMHVGNKKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIKDLSPKET 582
            SAA    + VG       Y + R LG G F+VVKLA H  T  + A+KI+ K +L   + + +  E+QI+  L+HPHIIKL++  +     YIVTE    GE+FD + +  H +E EAR     +L  + Y H   IVHRDLK ENLLL +   + +IK+ADFGF    K   P  T
Sbjct:   14 SAAQPRPLRVGF------YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDA---NMNIKLADFGFGNFYKSGEPLST 181          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: KS6A2_HUMAN (Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens GN=RPS6KA2 PE=1 SV=2)

HSP 1 Score: 128.642 bits (322), Expect = 2.179e-29
Identity = 66/166 (39.76%), Postives = 103/166 (62.05%), Query Frame = 1

Query:   70 KMHVGNKKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSEL-DHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSD-IKIADFGFAKRIK 561
            ++H  N  F   Y +  ++G G++SV K  +H  T  + AVKI+ K K    +      EI+IL     HP+II L + YD+G   Y+V EL+ GGEL DRI+ + +++E+EA D++  + +TM Y+H  G+VHRDLKP N+L   E+   + I++ DFGFAK+++
Sbjct:  403 QLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE------EIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLR 562          

HSP 2 Score: 95.9005 bits (237), Expect = 1.565e-19
Identity = 51/156 (32.69%), Postives = 88/156 (56.41%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHL---ETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIKD 564
            + L + LG G++  V L   +   + GQ  A+K++ K  L   D     ME  IL+E++HP I+KL   +      Y++ + + GG+LF R+  +  +TE++ +  +  +   + ++H +GI++RDLKPEN+LL    ++  IKI DFG +K   D
Sbjct:   59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILL---DEEGHIKITDFGLSKEAID 211          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: CDPK4_PLAYO (Calcium-dependent protein kinase 4 OS=Plasmodium yoelii yoelii GN=CPK4 PE=3 SV=3)

HSP 1 Score: 128.642 bits (322), Expect = 2.179e-29
Identity = 67/168 (39.88%), Postives = 109/168 (64.88%), Query Frame = 1

Query:   85 NKKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDE-DYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLL-CSETDDSDIKIADFG------FAKRIKD 564
            N  F + Y   + LG G+F  V L+    TG + A+K++SKK +  + D Q+L+ E+++L  LDH +I+KL+E +++   +Y+V+++ +GGELFD I+++  + E +A  +IK +L  + YMHK  +VHRDLKPEN+LL     +D  IKI DFG      ++K++KD
Sbjct:   63 NVVFNEQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKD 230          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: CDPK4_PLABA (Calcium-dependent protein kinase 4 OS=Plasmodium berghei (strain Anka) GN=CPK4 PE=1 SV=2)

HSP 1 Score: 128.642 bits (322), Expect = 2.179e-29
Identity = 67/168 (39.88%), Postives = 109/168 (64.88%), Query Frame = 1

Query:   85 NKKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDE-DYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLL-CSETDDSDIKIADFG------FAKRIKD 564
            N  F + Y   + LG G+F  V L+    TG + A+K++SKK +  + D Q+L+ E+++L  LDH +I+KL+E +++   +Y+V+++ +GGELFD I+++  + E +A  +IK +L  + YMHK  +VHRDLKPEN+LL     +D  IKI DFG      ++K++KD
Sbjct:   63 NVVFNEQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKD 230          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: CDPK2_ARATH (Calcium-dependent protein kinase 2 OS=Arabidopsis thaliana GN=CPK2 PE=1 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 2.179e-29
Identity = 69/180 (38.33%), Postives = 107/180 (59.44%), Query Frame = 1

Query:   34 NQRKMGSAASANKMHVGNK--KFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKL-SDEDYQALMMEIQILSEL-DHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIK 561
            + R++ SA    +  +  K   F + Y L R+LG G F    L +   TG + A K +SK+KL +DED + +  EIQI+  L  HP++I +   Y++    ++V EL +GGELFDRI+ + HYTE++A +L + ++  +   H +G++HRDLKPEN L  S  +DS +K  DFG +   K
Sbjct:  160 HMRRVSSAGLRTESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCLEKGTGNEYACKSISKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMELCSGGELFDRIIQRGHYTERKAAELARTIVGVLEACHSLGVMHRDLKPENFLFVSREEDSLLKTIDFGLSMFFK 339          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: SIK1_HUMAN (Serine/threonine-protein kinase SIK1 OS=Homo sapiens GN=SIK1 PE=1 SV=2)

HSP 1 Score: 128.257 bits (321), Expect = 2.846e-29
Identity = 68/159 (42.77%), Postives = 92/159 (57.86%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIKDLSPKET 582
            Y + R LG G F+VVKLA H  T  + A+KI+ K +L   + + +  E+Q++  L+HPHIIKL++  +     YIVTE    GE+FD + +  H +E EAR     +L  + Y H   IVHRDLK ENLLL     + DIK+ADFGF    K   P  T
Sbjct:   27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLL---DGNMDIKLADFGFGNFYKSGEPLST 182          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: KS6A2_MOUSE (Ribosomal protein S6 kinase alpha-2 OS=Mus musculus GN=Rps6ka2 PE=2 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 2.846e-29
Identity = 67/166 (40.36%), Postives = 102/166 (61.45%), Query Frame = 1

Query:   70 KMHVGNKKFAQNYMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSEL-DHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSD-IKIADFGFAKRIK 561
            ++H  N  F   Y +  ++G G++SV K  +H  T  + AVKI+ K K    +      EI+IL     HP+II L + YD+G   Y+V EL+ GGEL DRI+ +  ++E+EA D++  +  TM Y+H  G+VHRDLKP N+L   E+ + + I+I DFGFAK+++
Sbjct:  403 QLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPSE------EIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLR 562          

HSP 2 Score: 95.9005 bits (237), Expect = 1.565e-19
Identity = 51/156 (32.69%), Postives = 88/156 (56.41%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHL---ETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAKRIKD 564
            + L + LG G++  V L   +   + GQ  A+K++ K  L   D     ME  IL+E++HP I+KL   +      Y++ + + GG+LF R+  +  +TE++ +  +  +   + ++H +GI++RDLKPEN+LL    ++  IKI DFG +K   D
Sbjct:   59 FELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILL---DEEGHIKITDFGLSKEATD 211          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: BRSK2_HUMAN (BR serine/threonine-protein kinase 2 OS=Homo sapiens GN=BRSK2 PE=1 SV=3)

HSP 1 Score: 128.257 bits (321), Expect = 2.846e-29
Identity = 66/148 (44.59%), Postives = 93/148 (62.84%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFA 549
            Y L + LG G   +VKL +H  T QK A+KIV+++KLS+     +  EI IL  ++HPH++KL + Y+     Y+V E V+GGELFD +V K   T KEAR   + ++  + + H   I HRDLKPENLLL    + ++I+IADFG A
Sbjct:   19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLL---DEKNNIRIADFGMA 163          

BLAST of CX300749 vs. ExPASy Swiss-Prot
Match: MYLKG_DICDI (Probable myosin light chain kinase DDB_G0275057 OS=Dictyostelium discoideum GN=DDB_G0275057 PE=3 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 3.717e-29
Identity = 63/149 (42.28%), Postives = 94/149 (63.09%), Query Frame = 1

Query:  106 YMLARELGSGAFSVVKLAMHLETGQKAAVKIVSKKKLSDEDYQALMMEIQILSELDHPHIIKLFETYDEGTDFYIVTELVAGGELFDRIVAKAHYTEKEARDLIKIMLETMAYMHKMGIVHRDLKPENLLLCSETDDSDIKIADFGFAK 552
            Y++ +ELG GAFSVV+      T  K A+K + KK +  +  + L  EI I+ ++ H +++ L E ++  +   +V ELV GGELF +IV +  +TEK AR++++ +   + Y+H  GI HRDLKPENLL   E +D  IKIADFG +K
Sbjct:   56 YVVGKELGRGAFSVVREGTRKTTSDKVALKYIEKKFVKKKHIEQLRREIDIMKKVKHENVLSLKEIFESDSHLTLVMELVTGGELFYKIVERGSFTEKGARNVVRQVCAGVEYLHSQGIAHRDLKPENLLCNGEGEDMTIKIADFGLSK 204