EY702238

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH3B_PONAB (Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Pongo abelii GN=IDH3B PE=2 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 1.727e-47
Identity = 97/193 (50.26%), Postives = 138/193 (71.50%), Query Frame = 1

Query:   70 TLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIG-KGH-RSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEI 642
            T+ PGDG+GPE+  +VK+VF+ A VPVE++EH++ +E+          + L S++ NKV + G + TP+  KG   S ++ LR++L+L+ANV    SLPGY TR+++++L+ IRE TEGE S LEH+  RGV+E LKI+TR  S R+A++AF YA   GR +V A+HKANIM+  DGLFL+CC EVAE YP+I
Sbjct:   52 TMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHL-SEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGECSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRSKVIAVHKANIMKLGDGLFLQCCEEVAELYPKI 243          

HSP 2 Score: 73.559 bits (179), Expect = 1.794e-12
Identity = 35/60 (58.33%), Postives = 43/60 (71.67%), Query Frame = 3

Query:  621 CREV----P*DTYEEVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTP 788
            C EV    P   +E + IDNCCM LV+NP  FDVLVMPNLYG+II +L AG++GG G+ P
Sbjct:  233 CEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVP 292          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH1_YEAST (Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial OS=Saccharomyces cerevisiae GN=IDH1 PE=1 SV=2)

HSP 1 Score: 189.889 bits (481), Expect = 1.727e-47
Identity = 98/200 (49.00%), Postives = 136/200 (68.00%), Query Frame = 1

Query:   64 TATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGK-GHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEK-YPEIHMRKL 657
            T TL PGDG+G EI +SV+ +F    +P++WE       I         +E++ES++RNK+GLKG   TP  + GH SLN+ LRK+L++YANV    SL G KTR  D++LI IRENTEGE+SGLEH+ V GVVESLK++TR  + R+A +AF +AK + R+ V+A+HKANIM+  DGLF     E+ +K YP+I +  +
Sbjct:   30 TVTLIPGDGVGKEITDSVRTIFEAENIPIDWET----INIKQTDHKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSI 225          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_THET8 (Isocitrate dehydrogenase [NADP] OS=Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) GN=icd PE=1 SV=2)

HSP 1 Score: 149.828 bits (377), Expect = 1.065e-46
Identity = 75/194 (38.66%), Postives = 117/194 (60.31%), Query Frame = 1

Query:   70 TLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPR-TQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDD--VNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEI 642
            T+ PGDGIGPE  E+  +V   A+ P+ +E    G  +  R   S +  E++ES+R+ +V LKGP+ TP+G G +S N+TLRK    YANVRP    P   T Y    ++L+ +REN E  Y+G+EH     V ++LK+I+ + S ++  +AF  A+  GR++V    K+NIM+  +G   +   +VA++YP+I
Sbjct:   23 TVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESIRKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAGRGIDLVVVRENVEDLYAGIEHMQTPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVAQEYPDI 216          

HSP 2 Score: 58.9214 bits (141), Expect = 1.065e-46
Identity = 26/50 (52.00%), Postives = 34/50 (68.00%), Query Frame = 3

Query:  654 VXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNG 803
            + +DN    LVK P  F+V+V  N+ GDI+SDL +G+IGGLG  PS N G
Sbjct:  221 IIVDNAAHQLVKRPEQFEVIVTTNMNGDILSDLTSGLIGGLGFAPSANIG 270          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH1_KLULA (Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial OS=Kluyveromyces lactis GN=IDH1 PE=3 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 1.909e-46
Identity = 100/214 (46.73%), Postives = 143/214 (66.82%), Query Frame = 1

Query:   25 LLPRAFSSDITPITATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYV-GTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGK-GHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREV-AEKYPEIHMRKL 657
            LLP+ +    T    TL PGDG+G E+ +SV ++F    +P++WE   + G E     Q      ++ES++RNKVGLKG   TP  + GH SLN+ LRK+L+++ANV    S+PG KTR ++++++ IRENTEGEYSGLEH+ V GVVESLKI+TR  S R+A +AF +A  + R+ V A+HKANIM+  DGLF     E+ A +YPE+ ++ +
Sbjct:   21 LLPKKYGGRYT---VTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQ-----RAVESLKRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNI 226          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: LEU3_SULTO (3-isopropylmalate dehydrogenase OS=Sulfolobus tokodaii GN=leuB PE=1 SV=3)

HSP 1 Score: 132.494 bits (332), Expect = 3.537e-41
Identity = 76/202 (37.62%), Postives = 118/202 (58.42%), Query Frame = 1

Query:   64 TATLFPGDGIGPEIAESVKQVFRTAE----VPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAE---KYPEIHM 648
            T  L  GDGIGPEI    K++         +P+E+ E   G     R    L  +SL+ + +  + LKGP    +G+    + + LR+  ++YAN+RP  S+PG  T+Y +V+++ +RENTE  Y G EH V  GV   +KIITR AS R+A+   ++A    R++V+ +HKAN+M+ TDGLF + CR V +   +Y E+++
Sbjct:    4 TVALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRALARYGEALPKDSLKIIDKADIILKGP----VGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGNVDILIVRENTEDLYKGFEHIVSDGVAVGMKIITRFASERIAKVGLNFA-LRRRKKVTCVHKANVMRITDGLFAEACRSVLKGKVEYSEMYV 200          

HSP 2 Score: 57.7658 bits (138), Expect = 3.537e-41
Identity = 25/54 (46.30%), Postives = 35/54 (64.81%), Query Frame = 3

Query:  645 YEEVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNGE 806
            Y E+ +D     LV+NP  FDV+V  N+YGDI+SD  + + G LG+ PS N G+
Sbjct:  195 YSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDEASQIAGSLGIAPSANIGD 248          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH3B_CAEEL (Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Caenorhabditis elegans GN=C37E2.1 PE=1 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 2.116e-37
Identity = 86/205 (41.95%), Postives = 133/205 (64.88%), Query Frame = 1

Query:   61 ITATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESV-RRNKVGLKGPM---ATPIGKGH-RSLNLTLRKELNLYANVRPCYSLPGYKTRYD-DVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEIHMRKL 657
            +  T+ PGDG+GPE+  +V+ + +   +P+E+EE ++      R+ S     ++ES+ R N V LKG +   A    +G  + LN+ LR+ L+L+ANV    +L G KTR+   ++ + +RE TEGEYS LEH++V GV+E LKI TR  + R+A++AF YA   GR++V+A+HKANIM+  DGLFL+ C  VA++YP+I    +
Sbjct:   43 LKVTIIPGDGVGPELIYTVQDIVKQTGIPIEFEEIFLSEVHYTRSSSIEN--AVESIGRNNNVALKGAIEESAVLHTEGELQGLNMRLRRSLDLFANVVHIKTLDGIKTRHGKQLDFVIVREQTEGEYSSLEHELVPGVIECLKISTRTKAERIAKFAFDYATKTGRKKVTAVHKANIMKLGDGLFLRTCEGVAKQYPKIQFESM 245          

HSP 2 Score: 67.781 bits (164), Expect = 9.845e-11
Identity = 30/60 (50.00%), Postives = 41/60 (68.33%), Query Frame = 3

Query:  624 REVP*DTYEEVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNG 803
            ++ P   +E + IDN CM LV  P  FDV+VMPNLYG+II +L AG++GG G+ P  + G
Sbjct:  235 KQYPKIQFESMIIDNTCMQLVSKPEQFDVMVMPNLYGNIIDNLAAGLVGGAGVVPGQSVG 294          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_RICBR (Isocitrate dehydrogenase [NADP] OS=Rickettsia bellii (strain RML369-C) GN=icd PE=3 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 2.340e-36
Identity = 84/202 (41.58%), Postives = 129/202 (63.86%), Query Frame = 1

Query:   46 SDITPITATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSF-LTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSL-PGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEIH 645
            ++ TPIT     GDGIGPEI E+V  + R AE  +  E   VG ++  +  S  ++ +S ES+ R  V LK P+ TP G G++SLN+T+RK L L+AN+RP  S  P  KT + ++NL  IREN E  Y+G+E++    + ES+K+I+R    ++  YAF YA  + R++V+ + K NIM+ +DG+F K   E+A++YP+I+
Sbjct:    2 AEFTPITIAY--GDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYVKHYSSGISEQSWESIERTGVILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPSVSFYPFTKTLHPNLNLTIIRENEEDLYAGIEYRQTHNMYESVKLISRTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHKVFNEIAKEYPQIN 201          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: LEU3_SULSO (3-isopropylmalate dehydrogenase OS=Sulfolobus solfataricus GN=leuB PE=3 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 6.810e-36
Identity = 65/187 (34.76%), Postives = 104/187 (55.61%), Query Frame = 1

Query:   73 LFPGDGIGPEIAESVKQVFRTA----EVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREV 621
            + PGDGIGPE+ E  K++         + ++  E   G     +    L   +L+ + +  + LKGP    +G+    + + LR+  ++YAN+RP  SLP  +++Y +V+L+ +RENTE  Y G E     GV  ++K+ T  AS R+   A +YA    R +V+ +HKAN+M+ TDGLF   CRE+
Sbjct:    7 VIPGDGIGPELYEGSKRIIAKLIEKYNLDIDLIEVEAGDVALNKYGEALPRHTLDVIEKADMILKGP----VGETAMDVVVKLRQMYDMYANIRPAKSLPNVQSKYPNVDLVIVRENTEDLYKGFEFVTSTGVTIAIKVTTEFASKRIVNVALNYALMR-RRKVTCVHKANVMRVTDGLFASVCREI 188          

HSP 2 Score: 57.7658 bits (138), Expect = 6.810e-36
Identity = 28/64 (43.75%), Postives = 41/64 (64.06%), Query Frame = 3

Query:  621 CREVP*D--TYEEVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNGE 806
            CRE+      +EE+ +D     LV++P+ FDV+V  N+YGDI+SD  + + G LGL PS N G+
Sbjct:  185 CREILKGKVNFEEMYVDAAAANLVRDPTRFDVIVTSNVYGDILSDEASQIAGSLGLAPSANIGD 248          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_RICCN (Isocitrate dehydrogenase [NADP] OS=Rickettsia conorii GN=icd PE=3 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 1.516e-35
Identity = 100/280 (35.71%), Postives = 155/280 (55.36%), Query Frame = 1

Query:   46 SDITPITATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQ-SFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSL-PGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEIHMRKLXSTIAA*CL*RIPAL------SMCW*CLTSMVTSLVTYVLG*LVDWA*PLVAIMGKEDCPA*TGHGSTPDIAGK 861
            ++ TPIT     GDGIGPEI E+V  + R AE  +  E   VG ++  +   S ++ ES ES++R  + LK P+ TP G G++SLN+T+RK L L+AN+RP  SL P  +T + ++NL  IREN E  Y+G+E++    + ES+K+I+     ++  YAF YA  + R++V  + K NIM+ +DG+  K   E+A++YP+I+       I    L   P +      S  +  + S V + ++  +G          A +G+        HGS PDIAGK
Sbjct:    2 AEFTPITIAY--GDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYKKHYTSGISEESWESIQRTGIILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPAVSLHPFTRTLHPNLNLTIIRENEEDLYAGIEYRQTHNMYESMKLISHTGCEKIIRYAFEYAVKNNRKKVMCLSKDNIMKFSDGVLHKVFNEIAKEYPQINNAHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGS------ANIGQHYAMFEAVHGSAPDIAGK 273          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_RICFE (Isocitrate dehydrogenase [NADP] OS=Rickettsia felis GN=icd PE=3 SV=2)

HSP 1 Score: 149.828 bits (377), Expect = 1.981e-35
Identity = 100/280 (35.71%), Postives = 154/280 (55.00%), Query Frame = 1

Query:   46 SDITPITATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQ-SFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSL-PGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEIHMRKLXSTIAA*CL*RIPAL------SMCW*CLTSMVTSLVTYVLG*LVDWA*PLVAIMGKEDCPA*TGHGSTPDIAGK 861
            ++ TPIT     GDGIGPEI E+V  + R AE  +  E   VG ++  +   S ++ ES ES++R  + LK P+ TP G G++SLN+T+RK L L+AN+RP  S  P   T +  +NL  IREN E  Y+G+E++    + ES+K+I+     ++  YAF YA  + R++V+ + K NIM+ +DG+F K   E+A++YP+I+       I    L   P +      S  +  + S V + ++  +G          A +G+        HGS PDIAGK
Sbjct:    2 AEFTPITIAY--GDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYKKHYTSGISEESWESIQRTGIILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPSVSFHPFTMTLHPHLNLTIIRENEEDLYAGIEYRQTHNMYESIKLISHTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGVFHKIFNEIAKEYPQINNEHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGS------ANIGQHYAMFEAVHGSAPDIAGK 273