EY702238

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: LEU3_METJA (3-isopropylmalate/3-methylmalate dehydrogenase OS=Methanocaldococcus jannaschii GN=leuB PE=1 SV=2)

HSP 1 Score: 110.153 bits (274), Expect = 7.352e-35
Identity = 67/191 (35.08%), Postives = 105/191 (54.97%), Query Frame = 1

Query:   82 GDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYA---KTHGRE-RVSAIHKANIMQKTDGLFLKCCREVAEKYPEI 642
            GDGIG E+  +  QV     +P E+     G E+  RT   L  E++E+       L G      G+    + + LR  L+ YAN+RP  +  G K    D++ + +RENTEG Y G+E ++  G+  + ++IT +A  R+  +AF+ A   K  G+E +V+  HKAN+++ TDGLF K   +VAE+Y +I
Sbjct:    9 GDGIGKEVVPATIQVLEATGLPFEFVYAEAGDEVYKRTGKALPEETIETALDCDAVLFGAA----GETAADVIVKLRHILDTYANIRPVKAYKGVKCLRPDIDYVIVRENTEGLYKGIEAEIDEGITIATRVITEKACERIFRFAFNLARERKKMGKEGKVTCAHKANVLKLTDGLFKKIFYKVAEEYDDI 195          

HSP 2 Score: 58.9214 bits (141), Expect = 7.352e-35
Identity = 27/53 (50.94%), Postives = 35/53 (66.04%), Query Frame = 3

Query:  648 EEVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNGE 806
            E+  ID   M ++  P  FDV+V  NL+GDI+SD  AG +GGLGL PS N G+
Sbjct:  198 EDYYIDAMNMYIITKPQVFDVVVTSNLFGDILSDGAAGTVGGLGLAPSANIGD 250          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_RICTY (Isocitrate dehydrogenase [NADP] OS=Rickettsia typhi GN=icd PE=3 SV=1)

HSP 1 Score: 145.976 bits (367), Expect = 2.860e-34
Identity = 97/280 (34.64%), Postives = 152/280 (54.29%), Query Frame = 1

Query:   46 SDITPITATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQ-SFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSL-PGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEIHMRKLXSTIAA*CL*RIPAL------SMCW*CLTSMVTSLVTYVLG*LVDWA*PLVAIMGKEDCPA*TGHGSTPDIAGK 861
            ++ TPIT     GDGIGPEI ++V  + R AE  +  E   VG ++  +   S ++ ES   ++R  + LK P+ TP   G++SLN+T+RK L L+AN+RP  S  P  +T + ++NL  IREN E  YSG+E++    + ESLK+I+     ++  YAF YA  + R++V+ + K NIM+ +DG+F +   E+A++YP+I        I    L   P +      S  +  + S V + ++  +G          A +G+        HGS PDIAGK
Sbjct:    2 AEFTPITIAY--GDGIGPEIMDAVLYILRQAEARISLETIEVGEKLYKKHYTSGISEESWNVIQRTGIILKAPITTPQSGGYKSLNVTIRKTLQLFANIRPAVSFHPFTRTLHPNLNLTIIRENEEDLYSGIEYRQTHNMYESLKLISHTGCKKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHRVFNEIAKEYPQIDNEHYIIDIGTAKLATTPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGS------ANIGQHYAMFEAVHGSAPDIAGK 273          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_ARCFU (Isocitrate dehydrogenase [NADP] OS=Archaeoglobus fulgidus GN=icd PE=1 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 6.071e-34
Identity = 74/214 (34.58%), Postives = 113/214 (52.80%), Query Frame = 1

Query:   76 FPGDGIGPEIAESVKQVFRTAE----VPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKT---RYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKI----------------------ITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEK 630
            F GDGIG ++  +  +V   A       V W + Y G +      ++L  ++L +++  +V LKGP+ TP+G G+RSLN+T+R+ L+LYANVRP Y L G  +     + VN +  RENTE  Y+G+E    RG  E+LK+                      I+  A+ R+   A  YA  + R+ V+ +HK NIM+ T+G F     EVA++
Sbjct:   33 FEGDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNYLPDDTLNAIKEFRVALKGPLTTPVGGGYRSLNVTIRQVLDLYANVRPVYYLKGVPSPIKHPEKVNFVIFRENTEDVYAGIEWP--RGSEEALKLIRFLKNEFGVTIREDSGIGIKPISEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVAKQ 244          

HSP 2 Score: 50.447 bits (119), Expect = 6.071e-34
Identity = 21/49 (42.86%), Postives = 30/49 (61.22%), Query Frame = 3

Query:  663 DNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNGEG 809
            DN    ++     +DV+ +PNL GD +SD  A +IGGLG+ P  N G+G
Sbjct:  277 DNMFQQILTRTDEYDVIALPNLNGDYLSDAAAALIGGLGIAPGSNIGDG 325          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_RICPR (Isocitrate dehydrogenase [NADP] OS=Rickettsia prowazekii GN=icd PE=3 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 8.321e-34
Identity = 97/277 (35.02%), Postives = 152/277 (54.87%), Query Frame = 1

Query:   55 TPITATLFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQ-SFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSL-PGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEIHMRKLXSTIAA*CL*RIPAL------SMCW*CLTSMVTSLVTYVLG*LVDWA*PLVAIMGKEDCPA*TGHGSTPDIAGK 861
            TPIT     GDGIGPEI E+V  + R AE  +  E   VG ++  +   S ++ ES + ++R  + LK P+ TP   G++SLN+T+RK L L+AN+RP  S  P  +T + ++NL  IREN E  YSG+E++    + ES+K+I+     ++  YAF YA  + R++V+ + K NIM+ +DG+F +   E+A++YP+I+       I    L   P +      S  +  + S V + ++  +G          A +G+        HGS PDIAGK
Sbjct:    5 TPITIAY--GDGIGPEIMEAVLYILRKAEARISLETIEVGEKLYKKHYTSGISEESWDVIQRTGIILKAPITTPQSGGYKSLNVTIRKTLQLFANIRPVVSFYPFTRTLHPNLNLTIIRENEEDLYSGVEYRQTHNMYESMKLISHTGCKKIIRYAFEYAIKNNRKKVTCLTKDNIMKFSDGIFHRVFNEIAKEYPQINNEHYIIDIGTAKLATKPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGS------ANIGQHYAMFEAVHGSAPDIAGK 273          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: LEU3_ARCFU (3-isopropylmalate dehydrogenase OS=Archaeoglobus fulgidus GN=leuB PE=3 SV=1)

HSP 1 Score: 139.813 bits (351), Expect = 2.050e-32
Identity = 76/190 (40.00%), Postives = 115/190 (60.53%), Query Frame = 1

Query:   73 LFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEI 642
            + PGDGIG E+ E+   +    ++P E+  +  G E   +    L  E+LE+ R++   L G      G+    + + LR+EL  +ANVRP  ++ G +  Y  ++++ +RENTE  Y G E      V E++++ITR+AS R+A YAF  AK  GR++V+A+HKAN+M+KT GLF   CREVA+ YPEI
Sbjct:    6 VIPGDGIGKEVMEAAMLILEKLDLPFEYSYYDAGDEALEKYGKALPDETLEACRKSDAVLFGAA----GETAADVIVRLRRELGTFANVRPAKAIEGIECLYPGLDIVVVRENTECLYMGFEFGF-GDVTEAIRVITREASERIARYAFELAKREGRKKVTALHKANVMKKTCGLFRDVCREVAKDYPEI 190          

HSP 2 Score: 72.7886 bits (177), Expect = 3.060e-12
Identity = 36/66 (54.55%), Postives = 44/66 (66.67%), Query Frame = 3

Query:  621 CREVP*D----TYEEVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNGE 806
            CREV  D     Y +  ID  CM LV +P  FDV+V  N++GDI+SDL AG++GGLGL PS N GE
Sbjct:  180 CREVAKDYPEIQYNDYYIDAACMYLVMDPFRFDVIVTTNMFGDIVSDLAAGLVGGLGLAPSANVGE 245          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_STRSL (Isocitrate dehydrogenase [NADP] OS=Streptococcus salivarius GN=icd PE=3 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 5.836e-31
Identity = 72/216 (33.33%), Postives = 115/216 (53.24%), Query Frame = 1

Query:   82 GDGIGPEIAESVKQVF-RTAEVP------VEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKT---RYDDVNLITIRENTEGEYSGLEHQV----VRGVVE-------------------SLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEK 630
            GDG+G +I ++ + +F +  EV       +EW+E   G +   +T  +L  E+LE++R + V +KGP+ TP+G G RSLN+ LR+EL+LYA VRP     G  +     +  N+   RENTE  Y+G+E +     V+ V+E                    +K I+ + S R+   A  YA  +  ++V+ +HK NI + T+G F K   EVA++
Sbjct:   25 GDGVGHDIWKNAQAIFDKAVEVAYEGKRHIEWQELLAGKKAYDKTGEWLPKETLEAIRESLVAIKGPLETPVGGGIRSLNVALRQELDLYACVRPVRYFDGVASPLKEPEKTNITIFRENTEDIYAGIEWEAGTADVKRVIEFLQTEMNVNKIRFPESSSIGIKPISIEGSKRLIRSAIDYALKNNLKKVTLVHKGNIQKFTEGGFRKWGYEVAQE 240          

HSP 2 Score: 46.9802 bits (110), Expect = 5.836e-31
Identity = 19/49 (38.78%), Postives = 29/49 (59.18%), Query Frame = 3

Query:  651 EVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCN 797
            ++  DN    ++ NP  FDV+ + NL GD  SD  A  +GG+G++P  N
Sbjct:  255 DIIADNFLQQILLNPEKFDVVALTNLNGDYASDALAAQVGGIGISPGAN 303          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH_AQUAE (Isocitrate dehydrogenase [NADP] OS=Aquifex aeolicus GN=icd PE=3 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 9.883e-31
Identity = 71/216 (32.87%), Postives = 109/216 (50.46%), Query Frame = 1

Query:   82 GDGIGPEIAESVKQVFRTA-------EVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKT---RYDDVNLITIRENTEGEYSGLEH-------QVVR------------GVVESLKIITRQAS----LRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEK 630
            GDGIGPEI +++  +  TA          + W E   G + + +T   L  E+L+ ++ + VG+KGP+ TP+GKG RS+N  LR+  + Y+ VRP Y + G  T     + V+L+  RENT+  Y+G+E        + VR            G  E + I  +  S     R    A  YA  + ++ V+ I K NIM+ T+G F+    EVAE+
Sbjct:   46 GDGIGPEITQAMLLIINTAVEKTYNGSKKIYWVELLAGDKAEEKTGERLPQETLDVLKESIVGIKGPLGTPVGKGVRSINSALRRAFDYYSAVRPVYWM-GQATPIPNPERVDLVVFRENTDDVYAGVEFFAGTPEAKKVREFLIKEMGAKEEGFPEDVGITVKPMSEFKTKRHVRKALRYALENNKKNVAVIGKGNIMKATEGAFINWAFEVAEE 260          

HSP 2 Score: 53.9138 bits (128), Expect = 9.883e-31
Identity = 26/53 (49.06%), Postives = 33/53 (62.26%), Query Frame = 3

Query:  651 EVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNGEG 809
            +V  D   M LV  P A+DV++  NL GD +SDL A +IGG G  PS N G+G
Sbjct:  284 KVITDQMLMQLVLKPEAWDVIIAQNLNGDYVSDLAASLIGGPGFVPSGNIGDG 336          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: AKSF_METJA (Homoisocitrate dehydrogenase OS=Methanocaldococcus jannaschii GN=aksF PE=1 SV=3)

HSP 1 Score: 94.7449 bits (234), Expect = 1.681e-30
Identity = 68/198 (34.34%), Postives = 109/198 (55.05%), Query Frame = 1

Query:   82 GDGIGPE-IAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIG---KGHRSLNLTLRKELNLYANVRPCYS-----LPGYKTRYD-----DVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKY 633
            GDGIG E I E++K +    E  +   E   G E   +  + L  +++E  +   + L G + +P     K ++S  +TLRK  +LYANVRP  +     L G    Y+     +++++ IRENTE  Y G E ++      + ++ITR+ S R+  +AF YA  + R++VS IHKAN+++ TDGLFL+   E+ + Y
Sbjct:    9 GDGIGKEVIPEAIKILNELGEFEIIKGE--AGLECLKKYGNALPEDTIEKAKEADIILFGAITSPKPGEVKNYKSPIITLRKMFHLYANVRPINNFGIGQLIGKIADYEFLNAKNIDIVIIRENTEDLYVGRE-RLENDTAIAERVITRKGSERIIRFAFEYAIKNNRKKVSCIHKANVLRITDGLFLEVFNEIKKHY 203          

HSP 2 Score: 59.6918 bits (143), Expect = 1.681e-30
Identity = 25/53 (47.17%), Postives = 38/53 (71.70%), Query Frame = 3

Query:  648 EEVXIDNCCMMLVKNPSAFDVLVMPNLYGDIISDLCAGVIGGLGLTPSCNNGE 806
            ++  +D+  M L+K+P  FDV+V  N++GDI+SD  + +IGGLGL PS N G+
Sbjct:  208 DDYLVDSTAMNLIKHPEKFDVIVTTNMFGDILSDEASALIGGLGLAPSANIGD 260          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: IDH4_ARATH (Putative isocitrate dehydrogenase [NAD] subunit-like 4 OS=Arabidopsis thaliana GN=IDH4 PE=5 SV=1)

HSP 1 Score: 132.88 bits (333), Expect = 2.505e-30
Identity = 74/193 (38.34%), Postives = 119/193 (61.66%), Query Frame = 1

Query:   91 IGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKI-ITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQK-TDGLFLKCCREVAEKYPEIHMRKLXS 663
            I   +  +V QV    + PV +E +     I  +  + LTWE ++S+R+NKV L G +   +  G        RKEL+L+A++  C++L G  +R+++V+++ IRENTEGEY+G EH+VV GV+ES ++ +T+  S R+A+YAF YA    R++V+A+H     +K  D  FL+ C+EVA+ YP I   ++ S
Sbjct:    8 IDSNVTNAVHQVMDAMQAPVYFETYI----IKGKNMNHLTWEVVDSIRKNKVCLNGRVNNSLCGG-------ARKELDLFASLVDCFNLNGQPSRHENVDIVVIRENTEGEYAGREHEVVPGVIESFQVTMTKFWSDRIAKYAFEYAHFSKRKKVTAVHNNGKYEKLADAFFLESCQEVAKMYPNITYNEIAS 189          

BLAST of EY702238 vs. ExPASy Swiss-Prot
Match: LEU3_METTH (3-isopropylmalate dehydrogenase OS=Methanobacterium thermoautotrophicum GN=leuB PE=3 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 4.274e-30
Identity = 92/271 (33.95%), Postives = 141/271 (52.03%), Query Frame = 1

Query:   73 LFPGDGIGPEIAESVKQVFRTAEVPVEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVNLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEIHMRKLXSTIAA*CL*RIPALSMCW*CLTSMVTSLVTYVLG*LVDWA*PLV--------AIMGKEDCPA*TGHGSTPDIAGK 861
            + PGDGIG E+ E+   +  T ++ +E+     G     RT + L  E+LE+V   +  L G      G+    + + LR+E +L+AN+RP  SLPG    Y D++ + +RENTE  Y G E     G V   +IITR AS R++++AF YA+  G ++V+A+HKAN+++KTDG+F     +VA +YP++          A  L   P         T + T+L   +L    D A  L+        A +G+++      HGS P IAGK
Sbjct:    8 VIPGDGIGVEVMEAALHILNTLDLDLEFIHADAGDACLKRTGTALPEETLEAVGEARATLFGAA----GESAADVIVRLRREFDLFANLRPVKSLPGVPCLYPDLDFVIVRENTEDLYVGDEEYTPEGAVAK-RIITRTASRRISQFAFQYAQKEGMQKVTAVHKANVLKKTDGIFRDEFYKVASEYPQMEATDYYVDATAMYLITQPQEFQ-----TIVTTNLFGDILS---DEAAGLIGGLGLAPSANIGEKNALFEPVHGSAPQIAGK 265