DR908378

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51A_RAT (Lanosterol 14-alpha demethylase OS=Rattus norvegicus GN=Cyp51a1 PE=2 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 4.321e-35
Identity = 82/194 (42.27%), Postives = 118/194 (60.82%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAG-AFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELISPF 579
            GRP T+ E+ G+LI  L AGQHTSS TS W G +L + K        EQK +  +    + ++ L ++++L RCIKE LRL PP++ ++R +    T QT  G  Y IP GH V  SP    RL   +     ++PDR+    +++ A+G  F+Y+ FG GRH C+GE FAY+QIK IWS +LR +EF+LI+ +
Sbjct:  293 GRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGEDLPPLTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAK---TPQTVAG--YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLINGY 478          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_MYCTU (Lanosterol 14-alpha demethylase OS=Mycobacterium tuberculosis GN=cyp51 PE=1 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 6.898e-33
Identity = 76/185 (41.08%), Postives = 114/185 (61.62%), Query Frame = 1

Query:   22 EVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELISP 576
            E+TG+ I+ +FAG HTSS T++WT   L+++++  +AV +E   L    G+ V    L ++  L   +KE LRLHPPLI+L+R +  +F VQ        I +G +V  SPA +NR+P  + +P  + P R+   R+ED     +++I FG GRH C+G  FA +QIKAI+S LLR +EFE+  P
Sbjct:  245 EITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGD-GRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHR-----IHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQP 422          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_MYCBO (Lanosterol 14-alpha demethylase OS=Mycobacterium bovis GN=cyp51 PE=3 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 6.898e-33
Identity = 76/185 (41.08%), Postives = 114/185 (61.62%), Query Frame = 1

Query:   22 EVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELISP 576
            E+TG+ I+ +FAG HTSS T++WT   L+++++  +AV +E   L    G+ V    L ++  L   +KE LRLHPPLI+L+R +  +F VQ        I +G +V  SPA +NR+P  + +P  + P R+   R+ED     +++I FG GRH C+G  FA +QIKAI+S LLR +EFE+  P
Sbjct:  245 EITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGD-GRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHR-----IHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQP 422          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_USTMA (Lanosterol 14-alpha demethylase OS=Ustilago maydis GN=ERG11 PE=3 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 2.807e-26
Identity = 80/226 (35.40%), Postives = 115/226 (50.88%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKK-HG--KRVDHDIL-AEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTV----------QTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGRE--------EDK--------AAGAFS-YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELISPFPE 585
            GR  +  E+  ++IA L AGQHTSS TS+W    L    E +  + EEQ ++    HG  + +D++     + +L   +KE LRLHPPL  ++R   SD  V          ++     Y IPKGH +  +P  +   P I+K+ D +DP R+             EDK        + GA S Y+ FG GRH C+GE FAYLQI  I +  +R F++ L S FP+
Sbjct:  307 GRALSGVEIAHMMIALLMAGQHTSSATSSWAFLRLASRPEIIEELYEEQLNVYSDGHGGLRELDYETQKTSVPLLDAVVKETLRLHPPLHSIMRYVKSDLAVPPTLSSPTSTKSEPDAHYVIPKGHYIMAAPGVSQVDPQIWKSSDQFDPHRWLDATTAAAMQDSGEDKQDFGFGMISTGANSPYLPFGAGRHRCIGEQFAYLQIGVILATFVRIFKWHLDSKFPD 532          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_TRYCR (Sterol 14-alpha demethylase OS=Trypanosoma cruzi GN=CYP51 PE=1 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 3.666e-26
Identity = 65/186 (34.95%), Postives = 114/186 (61.29%), Query Frame = 1

Query:   22 EVTGLLIAALFAGQHTSSITSTWTGAYLL--KYKEYLSAVQEEQKHLMKKHGKRVDHD-ILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELI 570
            EV G+++AA+FAGQHTS+IT++W+  +L+  K K++L  + +E    + +   ++++D ++ EM    RC++E++R  PPL+M++R   ++  V +     Y +PKG I+  SP  ++     + NP  +DP+R      ++K  GAF  I FG G H C+G+ FA LQ+K I +   R ++F+L+
Sbjct:  280 EVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKE----IDEFPAQLNYDNVMDEMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGS-----YVVPKGDIIACSPLLSHHDEEAFPNPRLWDPER------DEKVDGAF--IGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLL 448          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_ASHGO (Lanosterol 14-alpha demethylase OS=Ashbya gossypii GN=ERG11 PE=3 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 4.788e-26
Identity = 69/201 (34.33%), Postives = 103/201 (51.24%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRF--------APGREEDKAAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEF 561
            G   T+ ++  LLI  L  GQHTS+ TS W   +L +  +    + EEQ  ++    K + +++L EM +L + IKE LR+H PL  L R    D  V       Y IPK H V  SP F +     + N   ++P R+        + G + D   GA S      Y+ FGGGRH C+GE FAY+Q+  I+S ++R+ ++
Sbjct:  294 GVKMTDQQIANLLIGVLMGGQHTSAATSAWVLLHLAERPDIQEELYEEQMRVLDGGAKELTYELLQEMPLLNQVIKETLRMHHPLHSLFRKVTRDMPV---PNTSYVIPKDHYVLASPGFCHLSEEYFPNAKEFNPHRWDNDAASSVSTGEKVDYGFGAISKGVSSPYLPFGGGRHRCIGEGFAYMQLGTIFSVVVRSMKW 491          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_CUNEL (Lanosterol 14-alpha demethylase OS=Cunninghamella elegans GN=CYP51 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 1.820e-25
Identity = 67/207 (32.37%), Postives = 103/207 (49.76%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREE------------DKAAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFEL 567
            G    +  + G++IA LF GQHTS+ TS WT   L    + + A++EEQ   +      +  D L ++ +L   I+E LRLHPP+  ++R   +D  V  + G E  IPKG+ +  +P      P  +  P +Y+P R+    +             D   GA        ++ FG GRH C+GE F YLQ+K + S  +R F+F+L
Sbjct:  279 GTHIPDHHIAGMMIAVLFGGQHTSATTSAWTILELANRPDIIKALREEQIEKLGSLKADLTFDNLKDLPLLEAAIRETLRLHPPIFQMMRRVVADKIVYEKNGME--IPKGNFICAAPGVTQVDPTYFNEPTTYNPYRWIEKTDPVHQLEQGDDANIDYGFGAVGISSKSPFLPFGAGRHRCIGEQFGYLQLKTVISTFIRTFDFDL 483          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_YEAST (Lanosterol 14-alpha demethylase OS=Saccharomyces cerevisiae GN=ERG11 PE=1 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 7.645e-24
Identity = 68/201 (33.83%), Postives = 98/201 (48.76%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDR--------FAPGREEDKAAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEF 561
            G   T+ E+  LLI  L  GQHTS+ TS W   +L +  +    + EEQ  ++    K + +D+L EM +L + IKE LR+H PL  L R    D  V       Y IP G+ V  SP + +     + N   ++  R        ++ G E D   GA S      Y+ FGGGRH C+GE FAY Q+  + S  +R  ++
Sbjct:  296 GVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHV---PNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKW 493          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_CANGA (Lanosterol 14-alpha demethylase OS=Candida glabrata GN=ERG11 PE=3 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 8.452e-23
Identity = 65/202 (32.18%), Postives = 97/202 (48.02%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRF---------APGREEDKAAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEF 561
            G   T+ E+  LLI  L  GQHTS+ TS W   +L +  +    + +EQ  ++    K + +D L  M +L + IKE LRLH PL  L R    D  +       Y +P+ + V  SP + +     +  P+ ++  R+         A G E D   GA S      Y+ FGGGRH C+GE FAY Q+  + S  +R  ++
Sbjct:  297 GTKMTDQEIANLLIGVLMGGQHTSAATSAWCLLHLAERPDVQEELYQEQMRVLNNDTKELTYDDLQNMPLLNQMIKETLRLHHPLHSLFRKVMRDVAI---PNTSYVVPRDYHVLVSPGYTHLQEEFFPKPNEFNIHRWDGDAASSSAAGGDEVDYGFGAISKGVSSPYLPFGGGRHRCIGELFAYCQLGVLMSIFIRTMKW 495          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_SCHPO (Lanosterol 14-alpha demethylase erg11 OS=Schizosaccharomyces pombe GN=erg11 PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 2.459e-22
Identity = 66/209 (31.58%), Postives = 100/209 (47.85%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAA-------------GAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELISPFPEL 588
            GRP  E E+ G++IA L AGQHTS+ T  W  A L    E +  + EEQK ++ ++   +  D   +M +L   I+E LRLHPP+   +R    D  V    G +  IP  + +  +P         + +   +DP R+     ED+ A              A  Y+ FG GRH C+GE FAY+ +  I S  + ++ + LI   P +
Sbjct:  270 GRPLKEHEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGEN-LELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPV---PGSKIVIPANNYLLAAPGLTATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYMHLSTIISKFVHDYTWTLIGKVPNV 474