DR908274

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: TYSY_BOVIN (Thymidylate synthase OS=Bos taurus GN=TYMS PE=2 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 1.853e-63
Identity = 80/114 (70.18%), Postives = 92/114 (80.70%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            WD N SR++LD +G +DR EGDLGPVYGFQWR+FGA Y +M ++YSGQG DQL  VI+ IK NPNDRRI+L AWNP DL LMALPPCH   QFY+ NGELSCQ+YQRS DMG G
Sbjct:  112 WDANGSRDFLDGLGFSDRAEGDLGPVYGFQWRHFGAEYKDMDSEYSGQGVDQLQKVIDTIKTNPNDRRIILCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLG 225          

HSP 2 Score: 82.4185 bits (202), Expect = 1.853e-63
Identity = 35/48 (72.92%), Postives = 41/48 (85.42%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQ 483
            LGVPFNIASYALLT MIAH+ DL PGDF+H +GDAH+Y NH+ PL+ Q
Sbjct:  224 LGVPFNIASYALLTYMIAHITDLKPGDFVHTLGDAHIYLNHIEPLKTQ 271          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: TYSY_AGABI (Thymidylate synthase OS=Agaricus bisporus GN=tms1 PE=3 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 3.663e-60
Identity = 76/120 (63.33%), Postives = 89/120 (74.17%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYM------ANGELSCQMYQRSADMGPG 344
            WDGN S+ +L+S GL  R EGDLGPVYGFQWR+FGA Y +  ADY+G+G DQL + I KIK NP DRRI+LSAWNP D+  MALPPCHM  QFY+      A  ELSC M+QRSAD+G G
Sbjct:   85 WDGNGSKAFLESRGLGHRREGDLGPVYGFQWRHFGAEYEDCDADYAGKGVDQLRECIRKIKENPTDRRIILSAWNPKDIPSMALPPCHMLCQFYVHLPADTAKPELSCLMFQRSADLGLG 204          

HSP 2 Score: 78.1814 bits (191), Expect = 3.663e-60
Identity = 38/60 (63.33%), Postives = 45/60 (75.00%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILK 519
            LG+PFNIASYALLT MIAHV      + I  +GDAHVYR+HV  LE QLQ+ P+PFP L+
Sbjct:  203 LGIPFNIASYALLTHMIAHVTGTTARELIIQLGDAHVYRDHVEALEVQLQREPRPFPKLR 262          

HSP 3 Score: 33.113 bits (74), Expect = 3.663e-60
Identity = 14/27 (51.85%), Postives = 18/27 (66.67%), Query Frame = 3

Query:  537 DIDSFVAEDFKLIGYDPHQKIEMKMAV 617
            DI+ F   DF + GY+PH  I MKM+V
Sbjct:  270 DIEDFEYSDFVIEGYNPHPSIAMKMSV 296          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: DRTS_PLACH (Bifunctional dihydrofolate reductase-thymidylate synthase OS=Plasmodium chabaudi PE=3 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 4.054e-60
Identity = 70/114 (61.40%), Postives = 87/114 (76.32%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            W+ N +RE+LD+  L  RE  DLGP+YGFQWR+FGA YT+MHADY  +G DQL ++IN IKN+P  RRI+L AWN  DL  MALPPCH+  QFY+ +G+LSC MYQRS D+G G
Sbjct:  379 WEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTDMHADYKDKGVDQLKNIINLIKNDPTCRRIILCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLG 492          

HSP 2 Score: 95.5153 bits (236), Expect = 4.054e-60
Identity = 43/66 (65.15%), Postives = 52/66 (78.79%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKINPEKK 537
            LGVPFNIASY++ T MIA VC+L P +FIHV+G+AHVY NHV  L+ QL + P PFP LK+NPE K
Sbjct:  491 LGVPFNIASYSIFTYMIAQVCNLQPAEFIHVLGNAHVYNNHVESLKVQLNRTPYPFPTLKLNPEIK 556          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: DRTS_PLAVI (Bifunctional dihydrofolate reductase-thymidylate synthase OS=Plasmodium vivax PE=1 SV=2)

HSP 1 Score: 154.451 bits (389), Expect = 5.751e-59
Identity = 69/114 (60.53%), Postives = 85/114 (74.56%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            W+ N +RE+LD+  L  RE  DLGP+YGFQWR+FGA YTNMH +Y  +G DQL +VI+ IKN P  RRI+L AWN  DL  MALPPCH+  QFY+ +G+LSC MYQRS D+G G
Sbjct:  419 WEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMHDNYEDKGVDQLKNVIHLIKNEPTSRRIILCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLG 532          

HSP 2 Score: 94.7449 bits (234), Expect = 5.751e-59
Identity = 42/66 (63.64%), Postives = 52/66 (78.79%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKINPEKK 537
            LGVPFNIASY++ T MIA VC+L P  FIH++G+AHVY NHV  L+ QL ++P PFP LK+NPE K
Sbjct:  531 LGVPFNIASYSIFTHMIAQVCNLQPAQFIHILGNAHVYNNHVDSLKVQLNRIPYPFPTLKLNPEVK 596          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: TYSY_VZVO (Thymidylate synthase OS=Varicella-zoster virus (strain Oka vaccine) GN=ORF13 PE=3 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 1.913e-58
Identity = 66/114 (57.89%), Postives = 82/114 (71.93%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            WD   S ++L+  G   R  GDLGP+YGFQWR+FGA Y +  ++Y  QG DQL  VI+ IK NP  RR+++S+WNP D+ LM LPPCH   QFY+ANGELSCQ+YQRS DMG G
Sbjct:   97 WDIYGSSKFLNRNGFHKRHTGDLGPIYGFQWRHFGAEYKDCQSNYLQQGIDQLQTVIDTIKTNPESRRMIISSWNPKDIPLMVLPPCHTLCQFYVANGELSCQVYQRSGDMGLG 210          

HSP 2 Score: 85.1149 bits (209), Expect = 1.913e-58
Identity = 39/61 (63.93%), Postives = 46/61 (75.41%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKI 522
            LGVPFNIA YALLT ++AHV  L  GD IH +GDAH+Y NH+  L+ QL + PKPFP LKI
Sbjct:  209 LGVPFNIAGYALLTYIVAHVTGLKTGDLIHTMGDAHIYLNHIDALKVQLARSPKPFPCLKI 269          

HSP 3 Score: 33.113 bits (74), Expect = 1.913e-58
Identity = 13/27 (48.15%), Postives = 21/27 (77.78%), Query Frame = 3

Query:  537 DIDSFVAEDFKLIGYDPHQKIEMKMAV 617
            DI+ F  +DF+L GY+PH  ++M+MA+
Sbjct:  275 DINDFKWDDFQLDGYNPHPPLKMEMAL 301          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: TYSY_VZVD (Thymidylate synthase OS=Varicella-zoster virus (strain Dumas) GN=ORF13 PE=3 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 1.913e-58
Identity = 66/114 (57.89%), Postives = 82/114 (71.93%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            WD   S ++L+  G   R  GDLGP+YGFQWR+FGA Y +  ++Y  QG DQL  VI+ IK NP  RR+++S+WNP D+ LM LPPCH   QFY+ANGELSCQ+YQRS DMG G
Sbjct:   97 WDIYGSSKFLNRNGFHKRHTGDLGPIYGFQWRHFGAEYKDCQSNYLQQGIDQLQTVIDTIKTNPESRRMIISSWNPKDIPLMVLPPCHTLCQFYVANGELSCQVYQRSGDMGLG 210          

HSP 2 Score: 85.1149 bits (209), Expect = 1.913e-58
Identity = 39/61 (63.93%), Postives = 46/61 (75.41%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKI 522
            LGVPFNIA YALLT ++AHV  L  GD IH +GDAH+Y NH+  L+ QL + PKPFP LKI
Sbjct:  209 LGVPFNIAGYALLTYIVAHVTGLKTGDLIHTMGDAHIYLNHIDALKVQLARSPKPFPCLKI 269          

HSP 3 Score: 33.113 bits (74), Expect = 1.913e-58
Identity = 13/27 (48.15%), Postives = 21/27 (77.78%), Query Frame = 3

Query:  537 DIDSFVAEDFKLIGYDPHQKIEMKMAV 617
            DI+ F  +DF+L GY+PH  ++M+MA+
Sbjct:  275 DINDFKWDDFQLDGYNPHPPLKMEMAL 301          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: DRTS_TRYBB (Bifunctional dihydrofolate reductase-thymidylate synthase OS=Trypanosoma brucei brucei PE=3 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 2.828e-58
Identity = 70/114 (61.40%), Postives = 88/114 (77.19%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            WDGN SR +LDS GLTD +E DLGPVYGFQWR+FGA Y +   D  G+G DQ+ +++  +  NP+DRR++ +AWNP+ L  MALPPCHM AQFY++NGELSC +YQRS DMG G
Sbjct:  323 WDGNGSRAFLDSRGLTDYDEMDLGPVYGFQWRHFGADYISCKVDSEGKGVDQIANIVKSLIENPDDRRMICTAWNPAALPRMALPPCHMMAQFYVSNGELSCMLYQRSCDMGLG 436          

HSP 2 Score: 85.5001 bits (210), Expect = 2.828e-58
Identity = 36/66 (54.55%), Postives = 49/66 (74.24%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKINPEKK 537
            LGVPFNIASYALLT ++A    L PG+ +H +GDAHVY NHV P  +QL+++P+PFP +    +K+
Sbjct:  435 LGVPFNIASYALLTFLMAKASGLRPGELVHTLGDAHVYSNHVEPCRKQLKRVPRPFPFIVFKQDKE 500          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: DRTS_PLAFK (Bifunctional dihydrofolate reductase-thymidylate synthase OS=Plasmodium falciparum (isolate K1 / Thailand) PE=1 SV=2)

HSP 1 Score: 153.68 bits (387), Expect = 3.683e-58
Identity = 68/114 (59.65%), Postives = 86/114 (75.44%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            W+ N +RE+LD+  L  RE  DLGP+YGFQWR+FGA YTNM+ +Y  +G DQL ++IN IKN+P  RRI+L AWN  DL  MALPPCH+  QFY+ +G+LSC MYQRS D+G G
Sbjct:  404 WEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLG 517          

HSP 2 Score: 92.8189 bits (229), Expect = 3.683e-58
Identity = 41/66 (62.12%), Postives = 52/66 (78.79%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKINPEKK 537
            LGVPFNIASY++ T MIA VC+L P  FIHV+G+AHVY NH+  L+ QL ++P PFP LK+NP+ K
Sbjct:  516 LGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIK 581          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: DRTS_PLABA (Bifunctional dihydrofolate reductase-thymidylate synthase OS=Plasmodium berghei (strain Anka) PE=3 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 8.884e-57
Identity = 67/114 (58.77%), Postives = 86/114 (75.44%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYMANGELSCQMYQRSADMGPG 344
            W+ N +RE+LD+  L  RE  DLGP+YGFQWR+FGA YT+MH +Y  +G DQL ++IN IKN+P  RRI+L AWN  +L  MALPPCH+  QFY+ +G+LSC MYQRS D+G G
Sbjct:  383 WEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTDMHDNYKDKGVDQLKNIINLIKNDPTCRRIILCAWNVKNLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLG 496          

HSP 2 Score: 90.5077 bits (223), Expect = 8.884e-57
Identity = 40/66 (60.61%), Postives = 51/66 (77.27%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKINPEKK 537
            LGVPFNIASY++ T MIA VC+L   +FIHV+G+AHVY NH+  L+ QL + P PFP LK+NP+ K
Sbjct:  495 LGVPFNIASYSIFTYMIAQVCNLQAAEFIHVLGNAHVYNNHIESLKIQLNRTPYPFPTLKLNPDIK 560          

BLAST of DR908274 vs. ExPASy Swiss-Prot
Match: DRTS_LEIMA (Bifunctional dihydrofolate reductase-thymidylate synthase OS=Leishmania major PE=1 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.512e-56
Identity = 71/116 (61.21%), Postives = 88/116 (75.86%), Query Frame = 3

Query:    3 WDGNASREYLDSVGLTDREEGDLGPVYGFQWRNFGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQFYM--ANGELSCQMYQRSADMGPG 344
            WDGN SRE+LDS GLT+ +E DLGPVYGFQWR+FGA Y    A+Y G+G DQ+  ++  IK NPNDRR++++AWNP  L+ MALPPCH+ AQFY+     ELSC +YQRS DMG G
Sbjct:  314 WDGNGSREFLDSRGLTENKEMDLGPVYGFQWRHFGADYKGFEANYDGEGVDQIKLIVETIKTNPNDRRLLVTAWNPCALQKMALPPCHLLAQFYVNTDTSELSCMLYQRSCDMGLG 429          

HSP 2 Score: 83.1889 bits (204), Expect = 1.512e-56
Identity = 38/66 (57.58%), Postives = 48/66 (72.73%), Query Frame = 1

Query:  340 LGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNHVRPLEEQLQKLPKPFPILKINPEKK 537
            LGVPFNIASYALLT +IA    L PG+ +H +GDAHVYRNHV  L+ QL+++P  FP L    E++
Sbjct:  428 LGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYRNHVDALKAQLERVPHAFPTLIFKEERQ 493