CN185621

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: NUAK2_PONAB (NUAK family SNF1-like kinase 2 OS=Pongo abelii GN=NUAK2 PE=2 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 2.515e-46
Identity = 100/224 (44.64%), Postives = 143/224 (63.84%), Query Frame = 1

Query:   94 IERHNVSENPRAQAANALFGKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFN 762
            ++RH+   N R         +YE  + LG G + KV  AR+  +GR VA+K I K+KI     + +I+REI IM  LNHPHI+ ++EV    SKI  VME+   G+L+  I+ + + SE  +R +F+Q++SAV YCH   V HRDLK EN+LLD NGN+K++DFGLS +  Q +    L T CG+P Y +PEI++ K Y G +VD WS GV+L++L  G +PF+
Sbjct:   40 VKRHHHKHNLRH--------RYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFD 251          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: NUAK2_HUMAN (NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 2.515e-46
Identity = 100/224 (44.64%), Postives = 143/224 (63.84%), Query Frame = 1

Query:   94 IERHNVSENPRAQAANALFGKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFN 762
            ++RH+   N R         +YE  + LG G + KV  AR+  +GR VA+K I K+KI     + +I+REI IM  LNHPHI+ ++EV    SKI  VME+   G+L+  I+ + + SE  +R +F+Q++SAV YCH   V HRDLK EN+LLD NGN+K++DFGLS +  Q +    L T CG+P Y +PEI++ K Y G +VD WS GV+L++L  G +PF+
Sbjct:   40 VKRHHHKHNLRH--------RYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFD 251          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: SIK1_MOUSE (Serine/threonine-protein kinase SIK1 OS=Mus musculus GN=Sik1 PE=1 SV=2)

HSP 1 Score: 185.267 bits (469), Expect = 3.284e-46
Identity = 96/209 (45.93%), Postives = 138/209 (66.03%), Query Frame = 1

Query:  151 GKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKI-AKGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNL 774
            G Y++ + LG G FA V  AR  +    VA+K+I+K ++ SSNL   I RE+ +M+ LNHP+I+KLY+V+ TK  +Y V EF K GE+F  + + G  SE+ +R+ F Q++SAV YCH+  + HRDLK ENLLLD N ++K++DFG     +  +    L T  G+P Y APE+   K Y+G ++D+WS GV+L+VL  G LPF+ PNL
Sbjct:   25 GFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNL-EKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHIVHRDLKTENLLLDSNMDIKLADFGFG---NFYKPGEPLSTCVGSPPYAAPEVFEGKEYEGPQLDVWSLGVVLYVLVCGSLPFDGPNL 229          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: MRKA_DICDI (Probable serine/threonine-protein kinase MARK-A OS=Dictyostelium discoideum GN=mrkA PE=3 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 5.602e-46
Identity = 96/211 (45.50%), Postives = 134/211 (63.51%), Query Frame = 1

Query:  151 GKYELGKLLGCGAFAKV---YHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFA-KIAKGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPN 771
            G Y + K +G G F KV   YH +  +    VA+K+INK K+    L   ++RE+ IM+ L+HP+I++LYEV+ T   +Y +ME+   GE+    IA G  +E  +R +F Q++SA+ YCHS+   HRDLKPENLLLD N  +K+ DFGLS V         L T CG+P Y +PE++ +K Y+G  VD+WS GV+LFVL  GYLPF+  N
Sbjct:  107 GNYLVIKTIGRGQFGKVKLGYHKK--IPNEKVAIKIINKGKLDPETL-KMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNV---FTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLPFDGDN 311          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: Y7165_DICDI (Probable serine/threonine-protein kinase DDB_G0277165 OS=Dictyostelium discoideum GN=DDB_G0277165 PE=3 SV=1)

HSP 1 Score: 183.341 bits (464), Expect = 1.248e-45
Identity = 91/210 (43.33%), Postives = 136/210 (64.76%), Query Frame = 1

Query:  151 GKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSS-NLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFNDPNL 774
            G + +GK LG G   KV        G  V +K+INK  +++  ++   I+REI +M+ ++HP+ +K+YEV  T   ++ ++E+V+GGELF  +  KG      +  +FQQ+I  + YCHSR + HRDLKPENLLL  +  +K++DFG+ ++   +R D LLHT CG+P Y +PE++S   YDG K D+WSCGVIL+ L  G LPF+D N+
Sbjct:    7 GPFIIGKTLGQGTTGKVKLGFHKDTGFKVGIKIINKELLINKPSMRRKIEREIVLMKLIDHPNAMKMYEVYETSKYLFLILEYVEGGELFDYLVEKGGLESGEALFFFQQIIIGLEYCHSRNICHRDLKPENLLLSGDKRIKIADFGMGSI---VRKDMLLHTSCGSPHYASPEVVSGIDYDGQKADVWSCGVILYALLTGKLPFDDENI 213          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: NUAK2_RAT (NUAK family SNF1-like kinase 2 OS=Rattus norvegicus GN=Nuak2 PE=1 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 2.129e-45
Identity = 97/224 (43.30%), Postives = 144/224 (64.29%), Query Frame = 1

Query:   94 IERHNVSENPRAQAANALFGKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFN 762
            ++RH+   N R         +YE  + LG G + KV  AR+  +GR VA+K I K+KI     + +I+REI IM  LNHPHI+ ++EV    SKI  VME+   G+L+  I+ + R +E  +R +F+Q++SA+ YCH  G+ HRDLK EN+LLD +GN+K++DFGLS +  + +    L T CG+P Y +PEI++ K Y G +VD WS GV+L++L  G +PF+
Sbjct:   44 VKRHHHKHNLRH--------RYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLNERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDASGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFD 255          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: MRKC_DICDI (Probable serine/threonine-protein kinase MARK-C OS=Dictyostelium discoideum GN=mrkC PE=3 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 6.194e-45
Identity = 97/207 (46.86%), Postives = 134/207 (64.73%), Query Frame = 1

Query:  151 GKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKSK---IYCVMEFVKGGELFAKI-AKGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPF 759
            G YE+GK LG G F KV    ++    +VA+K I  NK+ S        REI IM+ L+HP+IVKL +V+  + +    Y ++E+V GGELF  I A+    E  +RK+F+Q+ISA+ YCH+  + HRDLKPENLLLD NG++K+SDFGLS   + I+   LL + CG+P Y APEIL  + Y G  VD+WS GVI++ +  G LP+
Sbjct:   44 GSYEVGKTLGNGTFGKVKLGTNICTKENVAIKFIKNNKL-SGKQKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFDYIVAREYIKEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGDIKISDFGLS---NNIQPGKLLESFCGSPLYAAPEILKAEKYLGPPVDIWSLGVIMYAVLCGNLPW 246          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: GIN4_YEAST (Serine/threonine-protein kinase GIN4 OS=Saccharomyces cerevisiae GN=GIN4 PE=1 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.057e-44
Identity = 98/221 (44.34%), Postives = 139/221 (62.90%), Query Frame = 1

Query:  151 GKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSN--------------LVSNIKREISIMRRLNHPHIVKLYEVLATKSKIYCVMEFVKGGELF-AKIAKGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDG-LLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFND 765
            G ++LG+ LG G+  KV  AR+   G+  AVKVI+K    + N              L   I+REI IM+ LNHP++++LY+V  T + +Y V+E+ + GELF   + +G   E  + ++F+Q+I  V YCH+ G+ HRDLKPENLLLD   N+K++DFG++A    + T+G LL T CG+P Y APEI+S   Y G   D+WSCGVILF L  G LPF++
Sbjct:   17 GPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAA----LETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDE 233          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: NUAK2_MOUSE (NUAK family SNF1-like kinase 2 OS=Mus musculus GN=Nuak2 PE=2 SV=2)

HSP 1 Score: 178.333 bits (451), Expect = 4.015e-44
Identity = 99/232 (42.67%), Postives = 144/232 (62.07%), Query Frame = 1

Query:   94 IERHNVSENPRAQAANALFGKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEV--------LATKSKIYCVMEFVKGGELFAKIA-KGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPFN 762
            ++RH+   N R         +YE  + LG G + KV  AR+  +GR VA+K I K+KI     + +I+REI IM  LNHPHI+ ++EV            SKI  VME+   G+L+  I+ + R SE  +R +F+Q++SA+ YCH  G+ HRDLK EN+LLD NGN+K++DFGLS +  + +    L T CG+P Y +PEI++ K Y G +VD WS GV+L++L  G +PF+
Sbjct:   44 VKRHHHKHNLRH--------RYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFD 263          

BLAST of CN185621 vs. ExPASy Swiss-Prot
Match: MRKB_DICDI (Probable serine/threonine-protein kinase MARK-B OS=Dictyostelium discoideum GN=mrkB PE=3 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 4.015e-44
Identity = 94/206 (45.63%), Postives = 133/206 (64.56%), Query Frame = 1

Query:  151 GKYELGKLLGCGAFAKVYHARDVLNGRSVAVKVINKNKIMSSNLVSNIKREISIMRRLNHPHIVKLYEVLATKS--KIYCVMEFVKGGELFAKI-AKGRFSEDLSRKYFQQLISAVGYCHSRGVFHRDLKPENLLLDENGNLKVSDFGLSAVKDQIRTDGLLHTLCGTPAYVAPEILSKKGYDGAKVDLWSCGVILFVLTAGYLPF 759
            G Y LGK +G G  +KV    ++L G+  A+K+    +I        I+REISI++RL H +I++L++ +      +I  ++E V GGELF  I A+GR SE   RK+F+Q++  + YCHS  V HRDLK ENLL+DE+GNLK+SDFG S +   I+   LL T CG+P Y  PEIL +K Y+G +VD+WS GVIL+ +  G LP+
Sbjct:   63 GNYLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERK---EIEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNI---IKPGNLLSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMVTGQLPW 262